| Basic information |
| Official Symbol | ZNF541 |
| Description | zinc finger protein 541 |
| Other Aliases | NA |
| Other Description | NA |
| Mutation type | premature termination 951:Q->TAG |
| Location | Scaffold000067_1:5387610 5413846 - |
| Wiki | Wikipedia GeneCard |
| Sequence |
| ZNF541 |
ATGGACCAGTACAGCCTTGGGGACGAGGGCACCCTTCCATCAGAAATGCACCTCCCTTCG TTTTCAGAGAGCCAAGGCCTCAACTGCAGTGACACCCTCAACCGAGAGTTGGGGCCCCAC ACGCGGGACCTGCTCTATGCTGGCCTGAGTGGTTTAGACCTGGACCCCAGTCTCCCAACG CCCGACGCACCCAGCGAGGCACTGGAGGACAACCTAGACACCCTGTCCCTGTACTCAGGG AAGGACAGTGATTCCGTGAAGCTGCTGGAAGAGTATGCAGATCCAGAATCTCAGACTTCC TTACCACTGGGGCTGGGTGCACTGAAGGTGCCCAAAGAGGCTGACGAAGGAGGCAGAGCC ACCTCAGGAAGTGCCCGGAAAGGCAAGCGGCAGCACGGTTCCCCTCAGAACCCACTTCTG GACTGCAGCCTCTGTGGGAAGGTGTTCAGCAGCGCCAGTTCTCTTAGCAAGCACTACCTG ACACACAGCCAGGAGAGGAAGCACGTCTGCAAGATCTGCAGCAAGGCCTTTAAGCGCCAG GATCATACCGGGCACATGCTCACCCACCAGAAGACCAAGCCCTTCGTGTGCATCGAGCAG GGCTGCAGCAAGAGCTACTGCGACTACCGCTCCCTGCGCCGCCACTACGAGGTCCAGCAC GGCCTGTGCGTCCTGAAGGAGGCCCCCCCAGAAGAGGAAGCCTGTGGGGACTCGCCCCAG GCCCCTGAGCCGGCCAGCCAGCCATCTGCCAGCAGCCTGCGGTCCCTGGTATCCCCGGAA GCTAGGTCCCCTGGCTCCCTCCTGCCCAACCGAGACCTCCTGCGCTGCATCGTGAGCAGC ATCGTCCACCAGAAGCTCCCTTCTCCAGGCCCTGCCCCAACCGGGCCTTCAGACAGTGAA GGGAAGAGTATGGCCTGTCCCTGCCTTCCCTCGTCAGGGGCCTCCTGCACCCCGGCCGGC ACCCCAGTGGCCCCAGGACCCCTGGGCACTGAGGTCCCTGAGGAGCTGCCTCCCACACAG AAGGAGCCAGCTGCTGACGTGTTCACAGCCGTCCATCCCAGGGTGAGCGAGAACAGTGCC CCTGACCCACCAGAGTCAGGGCCCCCGCTGCTCCAGCTCCCATCCACCCTGGAGGGCTGG CCCGAGGGCAGCTCCCTGCCTGCCTGCCTGCCTTTCCTGCGAGGCCAGACGGTCCCTGCC AGTTCCCAGCCATCGGGCCACAATTTCCAGTGGCTCCGGAACCTGCCGGGCTGCCCCAAG AGCAAAGGCAACAACGTGTTCGTGGTCCACAAGCCTTCCGTGGTGCCCGCCCGCGAGGGC TCCGAGTCTGGGCCTGGGTCCAGCAGCACCTGCCTGGCAGTGGAGCCCTCGTCTGGCTCA GGGGTCAGCCTGGAGGACATGCTACCCTTCCCCCCCACGCTCCCAAAGGCGCCCGGGGAG GTCTCCAGCGACCCCAGATACATCAGTGGGGAGGACGACTCCTGGGCTTCCAAGAAGAGT AGGTTGGACTGCGATTCGTACTCGTGGCAAAGCCCCGGGGAGCCTGGCCTGCAGGACGCC CAGAAACAGGGAGGGTTCCAGCCAGATGCCACACCACTTTTCCGGCAGCTGTTCCTGAAG TCGCAGGAGTCTCTGGTGAGCCACGAGCAGATGCAGGTGTTCCAGATGATCACCAAGTCC CAAAGGATCTTCTCCCACGCCCAGGTGGCGGCAGCCTCCTCCCAGCTCCCGGGGCCCGAG GGCAAGCAGGCTGCTGTGAAGCCACCGCAGGGGCCATGGCCGCTGCAGCCCCCACCACCG GCGTCCGCTGCTGACTCTCTTCATACCGGCCCTGGAAACCTGGGGCCAGAGGGATCCCCA GCCCGCAGGAGGAAAAACCTGCCAGTGGCTCCCAGAGAGACGTCCCCAGGCAGCACGAAG CGAGACTCAAAGGGAGGTCCAAAAGCGGCCACTGCTCTGCCTCCCCTCCCAGCGGCAGCC CTGGACCCTCCCGGGAACTCAGACCTCTCTTCCCTGGCCAAGCAGTTGCGATCATCGAAA GGGACCTTGGACCTGGGGGACATATTCCCTACTGCAGGCTCTCGGCAGCTGGGGGGCAAT GAGCTGGCGCCAGGAGCCCAGCTGTCCGGGAAGCAGGCCCAGTCCGAAAATGGCTCAACT TCTGGGGCCACAAAAGGTGAAAAGAGCCTAGCCTGCTCCCGGGGTGCAGGCTACAGGCTC TTCTCGGGCAGCTCCAGGGCCCAGCGGTTCTCAGGCTTCCGGAAAGAGAAGGTGAAGATG GACTTGTGCTGCGCGGCGTCGCCCAGCCAAGTAGCCATGGCCTCCTTCTCATCCGCCGGG CCGCCAGCCGACGCCCCCCGGGACTCGAAGTCCAAGCTGACAATATTCAACAGGATCCAG GGTGGAAACATCTACAGGCTCCCCCATCCGAAGGAGGAGAACGTGGCAGGCGGAAACCAG CAAAATGGGGGCCCCGCAGACTGGCCAGAGCCCAGGGGCACTTTCGTGTGCAAGAACTGC AGCCAGATGTTCTACACCGAGAAGGGGCTGAGCAGCCACATGTGTTTTCACAGCGAGCAG TGGCCGTCGCCTAGAGGCAAGCAGGAGCAGCAGATGTTTGGCATGGAGTTTTGCAAGCCA CCGAGGCAGGTGCTGAGGCCAGAGGGAGACGGACAGAGTCCCCCAGGAGCCAAGAAGCCC TTGGACAGCTCAGCCACAGCCCCTTTGGTTCCCCCCATGTCAGTCCCCATGGCTCCTGAA ATCCGACCCCCAGGGAGTTTGGCTGAGGTGGGTGCTCCCCAGAGATGGCCTCGAGTAACC ACACGTGGTTCTGTTCTCTAGGGACAAGAGAAAGACGGGGAGGAGAGAGATGGCAGGGAG AACAGCCAACACAGGAAGCGGAAGAAGCGCCCCCAGCCCTCTGGGGAGCCGGGTGCCGGA GGGTGCCACCAGAGCTGCCTGCGGTCTCCAGTGTTCCTGGTGGACCGCCTCCTGAAGGGC CTGTTCCAGTGCTCCCCCTACACGCCACCTCCCATGCTCAGCCCCATCCGGGAGGGCTCG GGGCTGTACTTCAGCACGCTCTGTTCCACGTCCACTCAGGCCAGTCCCGACCAGCTCGTC GGTTCTGCGTTTCACGTGGATGGCTCCTTTGACATCTGCGTGGTGAAGGATGACACCAAG ATCAGCATTGAACACATCAACCTCGGAAGCCGGTTCCAGGCCGAGATCCCGGAGCTCCAG GAGAGGTCACTGGCTGGGACTGACGAGCATGTCGCTTCTCTGGTCTGGAAGCCGTGGGGC GATGTGATGACCAACCCAGAGACGCAGGACAGAACAGAACTCTGCAACGTGGCGTGCTCT AGCGTGATGCCGGGCGGGGGCACCAACCTGGAGCTGGCACTGCACTGCCTGCACGACGCC CGGGGCGATGTGCAGGTGGCCTTGGAGACCCTCTTACTTGGAGGACCCCGGAAGCCTCGG GCTCACCCGCTCGCTGACTACCGCTACACATCAGACGTCTGGACACCCATGGAGAAGAGG CTCTTTAAGAAGGCGTTCTGTACCCACAAGAAGGACTTTTATCTGATACACAAGACGATC CAGACGAAGACCGTAGCCCAGTGCGTTGAGTATTACTACATCTGGAAAAAAATGATCAAG TTTGACTGCGGCCGAGCCCCAGGGCTAGAAAAGAGGGTTAAGAGAGAGCCAGATGAGGTA GAGAGGACAGAAGAAAAGATCCCTTGCAGCCCTCGAGAGAGACCCAGCCACCGTCCAACT CCCGAGCTAAAGATAAAGACCAAGAGTTACAGGAGGGAGTCCATTCTCAACTCCAGCCCC AGTGCAGGCCCCAAGCGGACCCCAGAGGCGCCAGGGAGTGTGGAGAGTCAGGGCGTGTTC CCCTGCAGAGAGTGTGAGGTGTTTGACAAGATCAAGAGTCGAAACGCCCACATGAAGCGG CACCGCCTTCAGGACCACGTGGAGCCTCTGGTCAGGGTGAAGTGGTCCGTGAAGCCCTTC CAGATTAAGGAGGAGGACGAGGAGGAGGAGGAGCTGGGCGCAGACATCAGCCCCCTGCAG TGG |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 1365 | 1 | 5189 | Premature termination 951:Q->TAG |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
MetAspGlnTyrSerLeuGlyAspGluGlyAlaLeuProSerGluMetHisLeuProSer
|||||||||||||||||||||||||||||| |||||||||||||||||||||||||||
MetAspGlnTyrSerLeuGlyAspGluGlyThrLeuProSerGluMetHisLeuProSer
ATGGACCAGTACAGCCTTGGGGACGAGGGCACCCTTCCATCAGAAATGCACCTCCCTTCG
PheSerGluSerGlnGlyLeuAsnCysSerAspThrLeuAsnArgAspLeuGlyProAsn
||||||||||||||||||||||||||||||||||||||||||||| |||||||||
PheSerGluSerGlnGlyLeuAsnCysSerAspThrLeuAsnArgGluLeuGlyProHis
TTTTCAGAGAGCCAAGGCCTCAACTGCAGTGACACCCTCAACCGAGAGTTGGGGCCCCAC
ThrArgGlyPheLeuTyrAlaGlyLeuSerGlyLeuAspProAspProSerLeuProThr
|||||| ||||||||||||||||||||||||||| ||||||||||||||||||
ThrArgAspLeuLeuTyrAlaGlyLeuSerGlyLeuAspLeuAspProSerLeuProThr
ACGCGGGACCTGCTCTATGCTGGCCTGAGTGGTTTAGACCTGGACCCCAGTCTCCCAACG
ProAspMetSerSerGluValLeuGluAspAsnLeuAspThrLeuSerLeuTyrSerGly
|||||| |||||| |||||||||||||||||||||||||||||||||||||||
ProAspAlaProSerGluAlaLeuGluAspAsnLeuAspThrLeuSerLeuTyrSerGly
CCCGACGCACCCAGCGAGGCACTGGAGGACAACCTAGACACCCTGTCCCTGTACTCAGGG
LysAspSerAspSerValLysLeuLeuGluGluTyrAlaAspSerGluSerGlnAlaSer
|||||||||||||||||||||||||||||||||||||||||| ||||||||| |||
LysAspSerAspSerValLysLeuLeuGluGluTyrAlaAspProGluSerGlnThrSer
AAGGACAGTGATTCCGTGAAGCTGCTGGAAGAGTATGCAGATCCAGAATCTCAGACTTCC
LeuGln{A} >>>> Target Intron 1 >>>> {sp}LeuGlyLeuGlyValLeu
||| {|} 2997 bp {||}|||||||||||| |||
LeuPro{A}++ ++{sp}LeuGlyLeuGlyAlaLeu
TTACCA{G}gt ag{AC}CTGGGGCTGGGTGCACTG
LysAla<->LysGluAlaAspGluGlyGlyArgAlaThrSerGlySerAlaArgLysGly
||| |||||||||||||||||||||||||||||||||||||||||||||||||||
LysValProLysGluAlaAspGluGlyGlyArgAlaThrSerGlySerAlaArgLysGly
AAGGTGCCCAAAGAGGCTGACGAAGGAGGCAGAGCCACCTCAGGAAGTGCCCGGAAAGGC
LysArgGlnHisSerSerProGlnAsnProLeuLeuAspCysSerLeuCysGlyLysVal
|||||||||||| |||||||||||||||||||||||||||||||||||||||||||||
LysArgGlnHisGlySerProGlnAsnProLeuLeuAspCysSerLeuCysGlyLysVal
AAGCGGCAGCACGGTTCCCCTCAGAACCCACTTCTGGACTGCAGCCTCTGTGGGAAGGTG
PheSerSerAlaSerSerLeuSerLysHisTyrLeuThrHisSerGlnGluArgLysHis
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
PheSerSerAlaSerSerLeuSerLysHisTyrLeuThrHisSerGlnGluArgLysHis
TTCAGCAGCGCCAGTTCTCTTAGCAAGCACTACCTGACACACAGCCAGGAGAGGAAGCAC
ValCysLysIleCysSerLysAlaPheLysArgGlnAspHis{Le} >>>> Target
||||||||||||||||||||||||||||||||||||||||||{||} 198
ValCysLysIleCysSerLysAlaPheLysArgGlnAspHis{Le}++
GTCTGCAAGATCTGCAGCAAGGCCTTTAAGCGCCAGGATCAT{CT}gt
Intron 2 >>>> {u}ThrGlyHisMetLeuThrHisGlnLysThrLysProPheVal
8 bp {|}||||||||||||||||||||||||||||||||||||||||||
++{u}ThrGlyHisMetLeuThrHisGlnLysThrLysProPheVal
ag{G}ACCGGGCACATGCTCACCCACCAGAAGACCAAGCCCTTCGTG
CysIleGluGlnGlyCysSerLysSerTyrCysAspTyrArgSerLeuArgArgHisTyr
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
CysIleGluGlnGlyCysSerLysSerTyrCysAspTyrArgSerLeuArgArgHisTyr
TGCATCGAGCAGGGCTGCAGCAAGAGCTACTGCGACTACCGCTCCCTGCGCCGCCACTAC
GluValHisHisGlyLeuCysIleLeuLysGluAlaProProGluGluGluAlaCysGly
|||||| |||||||||||| ||||||||||||||||||||||||||||||||||||
GluValGlnHisGlyLeuCysValLeuLysGluAlaProProGluGluGluAlaCysGly
GAGGTCCAGCACGGCCTGTGCGTCCTGAAGGAGGCCCCCCCAGAAGAGGAAGCCTGTGGG
AspSerProHisAlaHisGluSerAlaGlyGlnProProProSerSerLeuArgSerLeu
||||||||| ||| ||| ||| |||||| ||||||||||||||||||
AspSerProGlnAlaProGluProAlaSerGlnProSerAlaSerSerLeuArgSerLeu
GACTCGCCCCAGGCCCCTGAGCCGGCCAGCCAGCCATCTGCCAGCAGCCTGCGGTCCCTG
ValProProGluAlaArgSerProGlySerLeuLeuProHisArgAspLeuLeuArgArg
||| ||||||||||||||||||||||||||||||||| |||||||||||||||
ValSerProGluAlaArgSerProGlySerLeuLeuProAsnArgAspLeuLeuArgCys
GTATCCCCGGAAGCTAGGTCCCCTGGCTCCCTCCTGCCCAACCGAGACCTCCTGCGCTGC
IleValSerSerIleValHisGlnLysThrProSerProGlyProAlaProAlaGlyAla
||||||||||||||||||||||||||| ||||||||||||||||||||| |||
IleValSerSerIleValHisGlnLysLeuProSerProGlyProAlaProThrGlyPro
ATCGTGAGCAGCATCGTCCACCAGAAGCTCCCTTCTCCAGGCCCTGCCCCAACCGGGCCT
SerAspSerGluGlyArgAsnThrAlaCysProCysProAlaSerSerGlySerSerSer
||||||||||||||| |||||||||||| ||||||||| |||
SerAspSerGluGlyLysSerMetAlaCysProCysLeuProSerSerGly---AlaSer
TCAGACAGTGAAGGGAAGAGTATGGCCTGTCCCTGCCTTCCCTCGTCAGGG---GCCTCC
CysThrProAlaGlyProHisAlaAlaProAlaAlaLeuAspThrGluLeuProGluGlu
||||||||||||||| |||||| ||| |||||| |||||||||
CysThrProAlaGlyThrProValAlaProGlyProLeuGlyThrGluValProGluGlu
TGCACCCCGGCCGGCACCCCAGTGGCCCCAGGACCCCTGGGCACTGAGGTCCCTGAGGAG
ProCysLeuProGlnLysGluProAlaThrAspValPheThrAlaProAsnSerArgAla
||||||||||||||| ||||||||||||||| |||
LeuProProThrGlnLysGluProAlaAlaAspValPheThrAlaValHisProArgVal
CTGCCTCCCACACAGAAGGAGCCAGCTGCTGACGTGTTCACAGCCGTCCATCCCAGGGTG
AlaGluAsnGlyAlaProAspProProGluProGluProAspThrAlaLeuLeuGlnAla
|||||| |||||||||||||||||| ||| |||||||||
SerGluAsnSerAlaProAspProProGluSerGlyPro------ProLeuLeuGlnLeu
AGCGAGAACAGTGCCCCTGACCCACCAGAGTCAGGGCCC------CCGCTGCTCCAGCTC
ArgSerThrAlaGluCysTrpProGluGlyGlySerValProAlaCysLeuProLeuPhe
|||||| ||| |||||||||||| ||| |||||||||||||||
ProSerThrLeuGluGlyTrpProGluGlySerSerLeuProAlaCysLeuProPheLeu
CCATCCACCCTGGAGGGCTGGCCCGAGGGCAGCTCCCTGCCTGCCTGCCTGCCTTTCCTG
ArgGlyGlnThrValProAlaSerSerGlnProSerSerHisSerPheGlnTrpLeuArg
|||||||||||||||||||||||||||||||||||| ||| |||||||||||||||
ArgGlyGlnThrValProAlaSerSerGlnProSerGlyHisAsnPheGlnTrpLeuArg
CGAGGCCAGACGGTCCCTGCCAGTTCCCAGCCATCGGGCCACAATTTCCAGTGGCTCCGG
AsnLeuProGlyCysProLysSerLysGlyAsnAsnValPheValValHisLysProSer
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
AsnLeuProGlyCysProLysSerLysGlyAsnAsnValPheValValHisLysProSer
AACCTGCCGGGCTGCCCCAAGAGCAAAGGCAACAACGTGTTCGTGGTCCACAAGCCTTCC
AlaValProSerArgGluGlySerGluSerGlyProGlyProSerSerGlySerProSer
|||||| ||||||||||||||||||||||||||| ||||||
ValValProAlaArgGluGlySerGluSerGlyProGlySerSerSerThrCysLeuAla
GTGGTGCCCGCCCGCGAGGGCTCCGAGTCTGGGCCTGGGTCCAGCAGCACCTGCCTGGCA
GluGluSerProProGlyProGlyGlyGlyLeuGluAspAlaLeuProPheProAlaAla
||| ||| ||| ||||||||| ||||||||||||
ValGluProSerSerGlySerGlyValSerLeuGluAspMetLeuProPheProProThr
GTGGAGCCCTCGTCTGGCTCAGGGGTCAGCCTGGAGGACATGCTACCCTTCCCCCCCACG
LeuLeuArgValProAlaGluAlaProSerAspProArgSerAlaSerGlyGluAspAsp
||| ||| ||| |||||||||||| |||||||||||||||
LeuProLysAlaProGlyGluValSerSerAspProArgTyrIleSerGlyGluAspAsp
CTCCCAAAGGCGCCCGGGGAGGTCTCCAGCGACCCCAGATACATCAGTGGGGAGGACGAC
ProCysAlaProLysLysValLysValAspCysAspSerPheLeuCysGlnAsnProGly
||| |||||| |||||||||||| ||| ||||||
SerTrpAlaSerLysLysSerArgLeuAspCysAspSerTyrSerTrpGlnSerProGly
TCCTGGGCTTCCAAGAAGAGTAGGTTGGACTGCGATTCGTACTCGTGGCAAAGCCCCGGG
GluProGlyLeuGlnGluAlaGlnLysAlaGlyGlyLeuProAlaAspAlaSerProLeu
||||||||||||||| ||||||||| |||||| |||||| ||||||
GluProGlyLeuGlnAspAlaGlnLysGlnGlyGlyPheGlnProAspAlaThrProLeu
GAGCCTGGCCTGCAGGACGCCCAGAAACAGGGAGGGTTCCAGCCAGATGCCACACCACTT
PheArgGlnLeuPheLeuLysSerGlnGluProLeuValSerHisGluGlnMetGlnVal
|||||||||||||||||||||||||||||| |||||||||||||||||||||||||||
PheArgGlnLeuPheLeuLysSerGlnGluSerLeuValSerHisGluGlnMetGlnVal
TTCCGGCAGCTGTTCCTGAAGTCGCAGGAGTCTCTGGTGAGCCACGAGCAGATGCAGGTG
PheGlnMetIleThrLysSerGlnArgIlePheSerHisAlaGlnValAlaAlaValSer
|||||||||||||||||||||||||||||||||||||||||||||||||||||| |||
PheGlnMetIleThrLysSerGlnArgIlePheSerHisAlaGlnValAlaAlaAlaSer
TTCCAGATGATCACCAAGTCCCAAAGGATCTTCTCCCACGCCCAGGTGGCGGCAGCCTCC
SerGlnLeuProAlaProGluGlyLysProAlaAlaLeuArgProLeuGlnGlyProTrp
|||||||||||| |||||||||||| |||||| ||| ||||||||||||
SerGlnLeuProGlyProGluGlyLysGlnAlaAlaValLysProProGlnGlyProTrp
TCCCAGCTCCCGGGGCCCGAGGGCAAGCAGGCTGCTGTGAAGCCACCGCAGGGGCCATGG
ProGlnGlnProProProLeuAlaProAlaValAspSerLeuHisAlaGlyProGlyAsn
||| |||||||||||| ||| ||| |||||||||||| ||||||||||||
ProLeuGlnProProProProAlaSerAlaAlaAspSerLeuHisThrGlyProGlyAsn
CCGCTGCAGCCCCCACCACCGGCGTCCGCTGCTGACTCTCTTCATACCGGCCCTGGAAAC
ProGluAlaGluGlySerProAlaArgArgArgLysThrThrProGlyValProArgGlu
||||||||||||||||||||||||||| ||| |||||||||
LeuGlyProGluGlySerProAlaArgArgArgLysAsnLeuProValAlaProArgGlu
CTGGGGCCAGAGGGATCCCCAGCCCGCAGGAGGAAAAACCTGCCAGTGGCTCCCAGAGAG
AlaSerProGlySerThrArgArgAspAlaLysGlyGlyLeuLysValAlaAlaValPro
||||||||||||||| |||||| ||||||||| ||| |||
ThrSerProGlySerThrLysArgAspSerLysGlyGlyProLysAlaAlaThrAlaLeu
ACGTCCCCAGGCAGCACGAAGCGAGACTCAAAGGGAGGTCCAAAAGCGGCCACTGCTCTG
ThrProLeuAlaAlaProSerLeuAspProSerArgAsnProAspIleSerSerLeuAla
|||||| ||| ||||||||| ||| ||| ||||||||||||
ProProLeuProAlaAlaAlaLeuAspProProGlyAsnSerAspLeuSerSerLeuAla
CCTCCCCTCCCAGCGGCAGCCCTGGACCCTCCCGGGAACTCAGACCTCTCTTCCCTGGCC
LysGlnLeuArgSerSerLysGlyThrLeuAspLeuGluAspIlePheProSerThrGly
|||||||||||||||||||||||||||||||||||| |||||||||||| |||
LysGlnLeuArgSerSerLysGlyThrLeuAspLeuGlyAspIlePheProThrAlaGly
AAGCAGTTGCGATCATCGAAAGGGACCTTGGACCTGGGGGACATATTCCCTACTGCAGGC
GlnArgGlnThrGlnLeuGlyGlyGluGluProProGlyAlaSerLeuProGlyLysGln
|||||| ||| ||| ||||||||| ||| |||||||||
SerArgGlnLeuGly---GlyAsnGluLeuAlaProGlyAlaGlnLeuSerGlyLysGln
TCTCGGCAGCTGGGG---GGCAATGAGCTGGCGCCAGGAGCCCAGCTGTCCGGGAAGCAG
AlaProAlaGluAsnGlyAlaAlaSerArgIleThrLysGlyGluLysGlyPro
||| ||||||||| ||| |||||||||||||||
AlaGlnSerGluAsnGlySerThrSerGlyAlaThrLysGlyGluLysSerLeu
GCCCAGTCCGAAAATGGCTCAACTTCTGGGGCCACAAAAGGTGAAAAGAGCCTA
AlaCysSerArgGlyGlyGlyTyrArgLeuLeu<->GlyAsnProArgAlaProArgPhe
||||||||||||||| |||||||||||| ||| |||||| ||||||
AlaCysSerArgGlyAlaGlyTyrArgLeuPheSerGlySerSerArgAlaGlnArgPhe
GCCTGCTCCCGGGGTGCAGGCTACAGGCTCTTCTCGGGCAGCTCCAGGGCCCAGCGGTTC
SerGlyPheArgLysGluLysAlaLysMetAspMetCysCysAlaAlaSerProSerGln
||||||||||||||||||||| ||||||||| ||||||||||||||||||||||||
SerGlyPheArgLysGluLysValLysMetAspLeuCysCysAlaAlaSerProSerGln
TCAGGCTTCCGGAAAGAGAAGGTGAAGATGGACTTGTGCTGCGCGGCGTCGCCCAGCCAA
ValAlaMetAlaSerPheSerSerAlaGlyProProAlaAsp<-><-><->ProSerLys
|||||||||||||||||||||||||||||||||||||||||| ||||||
ValAlaMetAlaSerPheSerSerAlaGlyProProAlaAspAlaProArgAspSerLys
GTAGCCATGGCCTCCTTCTCATCCGCCGGGCCGCCAGCCGACGCCCCCCGGGACTCGAAG
SerLysLeuThrIlePheSerArgIleGln >>>> Target Intron 1 >>>> G
|||||||||||||||||| ||||||||| 2143 bp |
SerLysLeuThrIlePheAsnArgIleGln++ ++G
TCCAAGCTGACAATATTCAACAGGATCCAGgt agG
lyGlyAsnIleTyrArgLeuProHisProValLysGluGluAsnValAlaGlyArg{Gl}
||||||||||||||||||||||||||||| ||||||||||||||||||||| { }
lyGlyAsnIleTyrArgLeuProHisPro---LysGluGluAsnValAlaGlyGly{Cy}
GTGGAAACATCTACAGGCTCCCCCATCCG---AAGGAGGAGAACGTGGCAGGCGGA{TG}
>>>> Target Intron 2 >>>> {y}AsnGlnGlnAsnGlySerProThrAspT
258 bp { }||||||||||||||| ||| ||||
++ ++{s}AsnGlnGlnAsnGlyGlyProAlaAspT
gt ag{T}AACCAGCAAAATGGGGGCCCCGCAGACT
rpThrLysProArgSerThrPheValCysLysAsnCysSerGlnMetPheTyrThrGluL
|| |||||| |||||||||||||||||||||||||||||||||||||||||||
rpProGluProArgGlyThrPheValCysLysAsnCysSerGlnMetPheTyrThrGluL
GGCCAGAGCCCAGGGGCACTTTCGTGTGCAAGAACTGCAGCCAGATGTTCTACACCGAGA
ysGlyLeuSerSerHisMetCysPheHisSerAspGlnTrpProSerProArgGlyLysG
|||||||||||||||||||||||||||||||| |||||||||||||||||||||||||
ysGlyLeuSerSerHisMetCysPheHisSerGluGlnTrpProSerProArgGlyLysG
AGGGGCTGAGCAGCCACATGTGTTTTCACAGCGAGCAGTGGCCGTCGCCTAGAGGCAAGC
lnGluProGln >>>> Target Intron 3 >>>> ValPheGlyThrGluPheCy
||||| ||| 219 bp |||||| ||||||||
lnGluGlnGln++ ++MetPheGlyMetGluPheCy
AGGAGCAGCAGgt agATGTTTGGCATGGAGTTTTG
sLysProLeuArgGlnValLeuArgProGluGlyAspArgHisSerProProGlyThrLy
||||||| ||||||||||||||||||||||||||| |||||||||||| ||
sLysProProArgGlnValLeuArgProGluGlyAspGlyGlnSerProProGlyAlaLy
CAAGCCACCGAGGCAGGTGCTGAGGCCAGAGGGAGACGGACAGAGTCCCCCAGGAGCCAA
sLysProLeuAspProThrAlaAlaAlaProLeuValValProGlnSerIleProValVa
||||||||||||| ||| |||||||||||| ||| ||| |||
sLysProLeuAspSerSerAlaThrAlaProLeuValProProMetSerValProMetAl
GAAGCCCTTGGACAGCTCAGCCACAGCCCCTTTGGTTCCCCCCATGTCAGTCCCCATGGC
lProValThrArgHisIleGlySerMetAlaMetMetGluTrpCysSer >>>> Targ
||| ||| |||||| |||
aProGluIleArgProProGlySerLeuAlaGluValGlyAlaProGln--
TCCTGAAATCCGACCCCCAGGGAGTTTGGCTGAGGTGGGTGCTCCCCAGcc
et Intron 4 >>>> ArgTrpLeuGlnAlaThrThrCysGlySerLysLeuLeuGln
1145 bp |||||| |||||| |||||| |||
++ArgTrpProArgValThrThrArgGlySer---ValLeu***
agAGATGGCCTCGAGTAACCACACGTGGTTCT---GTTCTCTAG
GlyGlnGluLysAspGlyGluGluArgAspSerLysGluSerSerGlnGlnArgLysArg
|||||||||||||||||||||||||||||| ||| |||||| |||||||||
GlyGlnGluLysAspGlyGluGluArgAspGlyArgGluAsnSerGlnHisArgLysArg
GGACAAGAGAAAGACGGGGAGGAGAGAGATGGCAGGGAGAACAGCCAACACAGGAAGCGG
LysLysArgProProPro{Se} >>>> Target Intron 5 >>>> {r}ThrAla
|||||||||||| |||{ } 30 bp { }
LysLysArgProGlnPro{Ly}+- +-{s}---Ser
AAGAAGCGCCCCCAGCCC{AA}gg ac{G}---TCT
GlyGluProGlyProAlaGlyCysHisGlnSerArgLeuArgSerProMetPheLeuVal
|||||||||||| ||||||||||||||| |||||||||||| |||||||||
GlyGluProGlyAlaGlyGlyCysHisGlnSerCysLeuArgSerProValPheLeuVal
GGGGAGCCGGGTGCCGGAGGGTGCCACCAGAGCTGCCTGCGGTCTCCAGTGTTCCTGGTG
AspCysLeuLeuLysGlyLeuPheGlnCysSerProTyrThrProProProMetLeuSer
||| ||||||||||||||||||||||||||||||||||||||||||||||||||||||
AspArgLeuLeuLysGlyLeuPheGlnCysSerProTyrThrProProProMetLeuSer
GACCGCCTCCTGAAGGGCCTGTTCCAGTGCTCCCCCTACACGCCACCTCCCATGCTCAGC
ProIleArgGluGlySerGlyValTyrPheAsnThrLeuCysSerThrSerThrGlnAla
||||||||||||||||||||| |||||| |||||||||||||||||||||||||||
ProIleArgGluGlySerGlyLeuTyrPheSerThrLeuCysSerThrSerThrGlnAla
CCCATCCGGGAGGGCTCGGGGCTGTACTTCAGCACGCTCTGTTCCACGTCCACTCAGGCC
SerProAspGlnLeuIleSerSerMetLeu{A} >>>> Target Intron 6 >>>>
||||||||||||||| ||| { } 4353 bp
SerProAspGlnLeuValGlySerAlaPhe{G}++
AGTCCCGACCAGCTCGTCGGTTCTGCGTTT{G}gt
{sp}GlnValAspGlySerPheGlyIleCysValValLysAspAspThrLysIleSer
{ } ||||||||||||||| |||||||||||||||||||||||||||||||||
++{ly}HisValAspGlySerPheAspIleCysValValLysAspAspThrLysIleSer
ag{GT}CACGTGGATGGCTCCTTTGACATCTGCGTGGTGAAGGATGACACCAAGATCAGC
IleGlu{Pr} >>>> Target Intron 7 >>>> {o}HisIleAsnIleGlySer
||||||{||} 591 bp {|}||||||||| ||||||
IleGlu{Pr}++ ++{o}HisIleAsnLeuGlySer
ATTGAA{CC}gt ag{A}CACATCAACCTCGGAAGC
ArgPheGlnAlaGluIleProGluLeuGlnGluArgSerLeuAlaGlyThrAspGluHis
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ArgPheGlnAlaGluIleProGluLeuGlnGluArgSerLeuAlaGlyThrAspGluHis
CGGTTCCAGGCCGAGATCCCGGAGCTCCAGGAGAGGTCACTGGCTGGGACTGACGAGCAT
ValAlaSerLeuValTrpLysProTrpGlyAspMetMetIleSerSerGluThrGlnAsp
||||||||||||||||||||||||||||||||| ||| ||||||||||||
ValAlaSerLeuValTrpLysProTrpGlyAspValMetThrAsnProGluThrGlnAsp
GTCGCTTCTCTGGTCTGGAAGCCGTGGGGCGATGTGATGACCAACCCAGAGACGCAGGAC
Arg{V} >>>> Target Intron 8 >>>> {al}ThrGluLeuCysAsnValAla
|||{|} 491 bp {||}|||||||||||||||||||||
Arg{V}++ ++{al}ThrGluLeuCysAsnValAla
AGA{G}gt ag{TG}ACAGAACTCTGCAACGTGGCG
CysSerSerValMetProGlyGlyGlyThrAsnLeuGluLeuAlaLeuHisCysLeuHis
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
CysSerSerValMetProGlyGlyGlyThrAsnLeuGluLeuAlaLeuHisCysLeuHis
TGCTCTAGCGTGATGCCGGGCGGGGGCACCAACCTGGAGCTGGCACTGCACTGCCTGCAC
GluAlaGlnGlyAsnValGln >>>> Target Intron 9 >>>> ValAlaLeuG
||| ||| |||||| 870 bp ||||||||||
AspAlaArgGlyAspValGln++ ++ValAlaLeuG
GACGCCCGGGGCGATGTGCAGgt agGTGGCCTTGG
luThrLeuLeuLeuArgGlyProHisLysProArgThrHisLeuLeuAlaAspTyrArgT
|||||||||||||| |||||| ||||||||| ||| ||||||||||||||||
luThrLeuLeuLeuGlyGlyProArgLysProArgAlaHisProLeuAlaAspTyrArgT
AGACCCTCTTACTTGGAGGACCCCGGAAGCCTCGGGCTCACCCGCTCGCTGACTACCGCT
yrThr{G} >>>> Target Intron 10 >>>> {ly}SerAspValTrpThrPro
|||||{|} 821 bp {||}||||||||||||||||||
yrThr{G}++ ++{ly}SerAspValTrpThrPro
ACACA{G}gt ag{GA}TCAGACGTCTGGACACCC
IleGluLysArgLeuPheLysLysAlaPheTyrAlaHisLysLysAspPheTyrLeuIle
||||||||||||||||||||||||||| ||||||||||||||||||||||||
MetGluLysArgLeuPheLysLysAlaPheCysThrHisLysLysAspPheTyrLeuIle
ATGGAGAAGAGGCTCTTTAAGAAGGCGTTCTGTACCCACAAGAAGGACTTTTATCTGATA
HisLysMet >>>> Target Intron 11 >>>> IleGlnThrLysThrValAla
|||||| 5978 bp |||||||||||||||||||||
HisLysThr++ ++IleGlnThrLysThrValAla
CACAAGACGgt agATCCAGACGAAGACCGTAGCC
GlnCysValGluTyrTyrTyrIleTrpLysLysMetIleLysPheAspCysGlyArgAla
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GlnCysValGluTyrTyrTyrIleTrpLysLysMetIleLysPheAspCysGlyArgAla
CAGTGCGTTGAGTATTACTACATCTGGAAAAAAATGATCAAGTTTGACTGCGGCCGAGCC
ProGlyLeuGluLysArgValLysArgGluProGluGluValGluArgThrGluGluLys
||||||||||||||||||||||||||||||||| ||||||||||||||||||||||||
ProGlyLeuGluLysArgValLysArgGluProAspGluValGluArgThrGluGluLys
CCAGGGCTAGAAAAGAGGGTTAAGAGAGAGCCAGATGAGGTAGAGAGGACAGAAGAAAAG
>>>> Target Intron 12 >>>> ValProCysSerProArgGluArgProSer
143 bp |||||||||||||||||||||||||||
++ ++IleProCysSerProArgGluArgProSer
gt agATCCCTTGCAGCCCTCGAGAGAGACCCAGC
HisHisProThrPro<-><->LysLeuLysThrLysSerTyrArgArgGluSerIleLeu
||| ||||||||| ||| |||||||||||||||||||||||||||||||||
HisArgProThrProGluLeuLysIleLysThrLysSerTyrArgArgGluSerIleLeu
CACCGTCCAACTCCCGAGCTAAAGATAAAGACCAAGAGTTACAGGAGGGAGTCCATTCTC
SerSerSerProAsnAlaGlySerLysArgThrProGluLeuLeuGlySerAlaGluSer
||||||||| |||||| ||||||||||||||| |||||| ||||||
AsnSerSerProSerAlaGlyProLysArgThrProGluAlaProGlySerValGluSer
AACTCCAGCCCCAGTGCAGGCCCCAAGCGGACCCCAGAGGCGCCAGGGAGTGTGGAGAGT
GlnGlyIlePheProCysArgGluCysGlu{Ar} >>>> Target Intron 13 >>
|||||| |||||||||||||||||||||{||} 100 bp
GlnGlyValPheProCysArgGluCysGlu{Ar}++
CAGGGCGTGTTCCCCTGCAGAGAGTGTGAG{AG}gt
>> {g}ValPheAspLysIleLysSerArgAsnAlaHisMetLysArgHisArgLeuGl
{|}|||||||||||||||||||||||||||||||||||||||||||||||||||||
++{g}ValPheAspLysIleLysSerArgAsnAlaHisMetLysArgHisArgLeuGl
ag{G}GTGTTTGACAAGATCAAGAGTCGAAACGCCCACATGAAGCGGCACCGCCTTCA
nAspHisValGluProIleIleArgValLysTrpProValLysProPheGlnLeuLys<-
|||||||||||||||| |||||||||||| ||||||||||||||| |||
nAspHisValGluProLeuValArgValLysTrpSerValLysProPheGlnIleLysGl
GGACCACGTGGAGCCTCTGGTCAGGGTGAAGTGGTCCGTGAAGCCCTTCCAGATTAAGGA
><-><-><-><->GluGluGluLeuGlyAlaAspIleGlyProLeuGlnTrp
|||||||||||||||||||||||| ||||||||||||
uGluAspGluGluGluGluGluLeuGlyAlaAspIleSerProLeuGlnTrp
GGAGGACGAGGAGGAGGAGGAGCTGGGCGCAGACATCAGCCCCCTGCAGTGG
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