| Basic information |
| Official Symbol | ZBTB7B |
| Description | zinc finger and BTB domain containing 7B |
| Other Aliases | RP11-307C12.9, THPOK, ZBTB15, ZFP-67, ZFP67, ZNF857B, c-KROX, hcKROX |
| Other Description | T-helper-inducing POZ/Krueppel-like factor; krueppel-related zinc finger protein cKrox; zinc finger and BTB domain containing 15; zinc finger and BTB domain-containing protein 7B; zinc finger protein 67 homolog; zinc finger protein 857B; zinc finger protein Th-POK |
| Mutation type | Delete and frame-shift 12:D->T, Delete and frame-shift 113:T->CG |
| Location | Scaffold000374_1:755537 761398 - |
| Wiki | Wikipedia GeneCard |
| Sequence |
| ZBTB7B |
CAACCTGGTTCTCGTCCTCCCTCACCCTGGCCCTGCTGCTGGAGAGGCCTACCCAGGCCC CTCTCGGGCTCCCTGGCAGAGCCGAGAAGAGAAGATGGGGAGCCCCGAGGATGACCTGAT TGGGATTCCGTTCCCCGACCACAGCAGCGAGCTCCTGAGCTGCCTCAATGAGCAGCGCCA GCTAGGCCACCTCTGCGACCTCACCATCCGGACGCAGGGCCTGGAATACCGTACCCACAG GGCCGGGCCGGCCGCCGGGGGTGCAGGGGCCGGAGTGTGCGAGCTGGACTTCGTAGGGCC GGAGGCGCTGGGCGCCCTGCTGGAGTTTGCCTACACAGCCACCCTGACTACCAGCAGCGC CAACATGCCGGCTGTGCTGCAGGCGGCCCGGCTGCTGGAGATCCCGTGCGTCATCGCCGC CTGCATGGAGATTCTGCAGGGCAGCGGGCTAGAAGCCCCCAGCCCCGACGAGGATGACTG TGAGCGAGCCCGCCAGTACCAGGAGGCCTTCCCCACAGCCACGGCCTCCGCCTCAGCCTC AGGAGTTCACAATGGTGAAGACAGCCCTCCACAGGTGCCCCTCCCGCCACCGCCACCACC ACCTAGGCCTGTCGCCCGCCGCAGCCGCAAGCCCCGCAAAGCTTTCCTGCAAACCAAGGG GGCCCGGGCGAACCACCTAGTACCAGAGGTGCCCTCGGTGCCTACACACCCCTTGACCTA TGAGGAGGAGGAAGTGGTGGGCAGAGGGGGCAGCAGTGGGGGCAGTGGGCTGGGGGACAG CTACAGCCCTCCCACAGGGACTGCCTCACCTCCTGAGGGGCCTCTGAGCTATGAGGCCTA TGAGGGGGAGGAAGAAGAGGAGGAGCTGGTCTACCCCCCTGCCTATGCCCTGGCACAGGG CAGTGGGCCTCCGCTGTCTCCAGAGGAGCTAGGCTCGGATGAAGATGCCATTGATCCTGA CCTGATGGCCTATCTAAGCTCCCTGCACCAGGATGCCCTAACACCGGGCTTGGACGGCCA GGACAAGCTGGTGCGCAAACGCCGCTCCCAGATGCCCCAGGAGTGCCCGGTCTGCCATAA GATCATCCACGGAGCAGGCAAGCTGCCGCGCCACATGCGAACCCACACGGGCGAGAAGCC CTTTGCCTGCGAAGTCTGCGGCGTCCGCTTCACAAACGACAAGCTCAAGATCCACATGCG GAAGCACACAGGAGAGCGCCCCTACTCGTGCCCGCACTGCCCGGCCCGCTTCCTGCACAG CTATGACCTCAAGAACCACATGCACCTGCACACGGGGGACCGGCCCTACGAGTGCCACCT GTGCCACAAGGCTTTCGCCAAGGAGGACCACCTGCAGCGCCACCTCAAGGGCCAGAACTG CCTGGAGGTGCGCACCCGGCGGCGCCGCAAGGACGATGCGCCACCCCACTATCCACCACC CTCCGCCACCACCCCTTCCCCGGCTGGTCTCGACCTCTCCAACGGCCACCTGGACTCCTT CCGCCTCTCTCTGGCTCGATTCTGGGAGCAGTCAGCCCCAACCGGGCCCCCGGTCTCCAC CCCGGGGCCTCCTGATGACGACGACGAGGAGGGAGCACCCACCACACCCCAGGCTGAAGG TGCCATGGAGTCCTCT |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 573 | 3 | 573 | Delete and frame-shift 12:D->T, Delete and frame-shift 113:T->CG |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
GlnProGlyProHisProProSerProGlnAlaAlaAlaProGlyGluAlaTrpProGly
||||||||| |||||||||||| ||| ||||||||| ||||||
GlnProGlySerArgProProSerPro---GlyProAlaAlaGlyGluAlaTyrProGly
CAACCTGGTTCTCGTCCTCCCTCACCCT##GGCCCTGCTGCTGGAGAGGCCTACCCAGGC
ProSerGlnAlaProTrpGlnSerLeuGlu >>>> Target Intron 1 >>>>
|||||| ||||||||||||||| ||| 3795 bp
ProSerArgAlaProTrpGlnSerArgGlu++ ++
CCCTCTCGGGCTCCCTGGCAGAGCCGAGAAgt ag
GluLysMetGlySerProGluAspAspLeuIleGlyIleProPheProAspHisSerSer
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GluLysMetGlySerProGluAspAspLeuIleGlyIleProPheProAspHisSerSer
GAGAAGATGGGGAGCCCCGAGGATGACCTGATTGGGATTCCGTTCCCCGACCACAGCAGC
GluLeuLeuSerCysLeuAsnGluGlnArgGlnLeuGlyHisLeuCysAspLeuThrIle
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GluLeuLeuSerCysLeuAsnGluGlnArgGlnLeuGlyHisLeuCysAspLeuThrIle
GAGCTCCTGAGCTGCCTCAATGAGCAGCGCCAGCTAGGCCACCTCTGCGACCTCACCATC
ArgThrGlnGlyLeuGluTyrArgThrHisArgAlaValLeuAlaAlaCysSerHis
||||||||||||||||||||||||||||||||||||
ArgThrGlnGlyLeuGluTyrArgThrHisArgAla---------------------
CGGACGCAGGGCCTGGAATACCGTACCCACAGGGCC---------------------
TyrPheLysLysLeuPheThrGluGlyGlyGlyGlyAlaValMetGlyAlaGlyThr
|||
---------------------------------------------------Gly---
---------------------------------------------------GGCCG#
AlaThrGlyGlyAlaGlyAlaGlyValCysGluLeuAspPheValGlyProGluAlaLeuGl
||| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
AlaAlaGlyGlyAlaGlyAlaGlyValCysGluLeuAspPheValGlyProGluAlaLeuGl
GCCGCCGGGGGTGCAGGGGCCGGAGTGTGCGAGCTGGACTTCGTAGGGCCGGAGGCGCTGGG
yAlaLeuLeuGluPheAlaTyrThrAlaThrLeuThrThrSerSerAlaAsnMetProAlaV
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
yAlaLeuLeuGluPheAlaTyrThrAlaThrLeuThrThrSerSerAlaAsnMetProAlaV
CGCCCTGCTGGAGTTTGCCTACACAGCCACCCTGACTACCAGCAGCGCCAACATGCCGGCTG
alLeuGlnAlaAlaArgLeuLeuGluIleProCysValIleAlaAlaCysMetGluIleLeu
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
alLeuGlnAlaAlaArgLeuLeuGluIleProCysValIleAlaAlaCysMetGluIleLeu
TGCTGCAGGCGGCCCGGCTGCTGGAGATCCCGTGCGTCATCGCCGCCTGCATGGAGATTCTG
GlnGlySerGlyLeuGluAlaProSerProAspGluAspAspCysGluArgAlaArgGlnTy
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GlnGlySerGlyLeuGluAlaProSerProAspGluAspAspCysGluArgAlaArgGlnTy
CAGGGCAGCGGGCTAGAAGCCCCCAGCCCCGACGAGGATGACTGTGAGCGAGCCCGCCAGTA
rLeuGluAlaPheAlaThrAlaThr<-><-><-><->AlaSerGlyValProAsnGlyGluA
| ||||||||| ||||||||| |||||||||||| ||||||||||
rGlnGluAlaPheProThrAlaThrAlaSerAlaSerAlaSerGlyValHisAsnGlyGluA
CCAGGAGGCCTTCCCCACAGCCACGGCCTCCGCCTCAGCCTCAGGAGTTCACAATGGTGAAG
spSerProProGlnValProLeuProProProProProProProProArgProValAlaArg
||||||||||||||||||||||| ||||||||||||||||||||||||||||||||||||
spSerProProGlnValProLeu---ProProProProProProProArgProValAlaArg
ACAGCCCTCCACAGGTGCCCCTC---CCGCCACCGCCACCACCACCTAGGCCTGTCGCCCGC
ArgSerArgLysProArgLysAlaPheLeuGlnThrLysGlyAlaArgAlaAsnHisLeuVa
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ArgSerArgLysProArgLysAlaPheLeuGlnThrLysGlyAlaArgAlaAsnHisLeuVa
CGCAGCCGCAAGCCCCGCAAAGCTTTCCTGCAAACCAAGGGGGCCCGGGCGAACCACCTAGT
lProGluValProThrValProAlaHisProLeuThrTyrGluGluGluGluValAlaGlyA
||||||||||||| |||||| |||||||||||||||||||||||||||||| ||||
lProGluValProSerValProThrHisProLeuThrTyrGluGluGluGluValValGlyA
ACCAGAGGTGCCCTCGGTGCCTACACACCCCTTGACCTATGAGGAGGAGGAAGTGGTGGGCA
rgValGlySerSerGlyGlySerGlyProGlyAspSerTyrSerProProThrGlyThrAla
|| ||||||||||||||||||||| |||||||||||||||||||||||||||||||||
rgGlyGlySerSerGlyGlySerGlyLeuGlyAspSerTyrSerProProThrGlyThrAla
GAGGGGGCAGCAGTGGGGGCAGTGGGCTGGGGGACAGCTACAGCCCTCCCACAGGGACTGCC
SerProProGluGlyProGlnSerTyrGluProTyrGluGlyGluGluGluGluGluGluLe
|||||||||||||||||| ||||||||| |||||||||||||||||||||||||||||
SerProProGluGlyProLeuSerTyrGluAlaTyrGluGlyGluGluGluGluGluGluLe
TCACCTCCTGAGGGGCCTCTGAGCTATGAGGCCTATGAGGGGGAGGAAGAAGAGGAGGAGCT
uValTyrProProAlaTyrGlyLeuAlaGlnGlyGlyGlyProProLeuSerProGluGluL
||||||||||||||||||| |||||||||||| |||||||||||||||||||||||||
uValTyrProProAlaTyrAlaLeuAlaGlnGlySerGlyProProLeuSerProGluGluL
GGTCTACCCCCCTGCCTATGCCCTGGCACAGGGCAGTGGGCCTCCGCTGTCTCCAGAGGAGC
euGlySerAspGluAspAlaIleAspProAspLeuMetAlaTyrLeuSerSerLeuHisGln
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
euGlySerAspGluAspAlaIleAspProAspLeuMetAlaTyrLeuSerSerLeuHisGln
TAGGCTCGGATGAAGATGCCATTGATCCTGACCTGATGGCCTATCTAAGCTCCCTGCACCAG
AspAsnLeuAlaProGlyLeuAspSerGlnAspLysLeuValArgLysArgArgSerGlnMe
||| ||| |||||||||||| |||||||||||||||||||||||||||||||||||
AspAlaLeuThrProGlyLeuAspGlyGlnAspLysLeuValArgLysArgArgSerGlnMe
GATGCCCTAACACCGGGCTTGGACGGCCAGGACAAGCTGGTGCGCAAACGCCGCTCCCAGAT
tProGlnGluCysProValCysHisLysIleIleHisGlyAlaGlyLysLeuProArgHisM
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
tProGlnGluCysProValCysHisLysIleIleHisGlyAlaGlyLysLeuProArgHisM
GCCCCAGGAGTGCCCGGTCTGCCATAAGATCATCCACGGAGCAGGCAAGCTGCCGCGCCACA
etArgThrHisThrGlyGluLysProPheAlaCysGluValCysGlyValArgPheThr{Ar
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||{||
etArgThrHisThrGlyGluLysProPheAlaCysGluValCysGlyValArgPheThr{Ar
TGCGAACCCACACGGGCGAGAAGCCCTTTGCCTGCGAAGTCTGCGGCGTCCGCTTCACA{CG
} >>>> Target Intron 1 >>>> {g}AsnAspLysLeuLysIleHisMetArgLy
} 429 bp {|}|||||||||||||||||||||||||||||
}++ ++{g}AsnAspLysLeuLysIleHisMetArgLy
}gt ag{G}AACGACAAGCTCAAGATCCACATGCGGAA
sHisThrGlyGluArgProTyrSerCysProHisCysProAlaArgPheLeuHisSerTyrA
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
sHisThrGlyGluArgProTyrSerCysProHisCysProAlaArgPheLeuHisSerTyrA
GCACACAGGAGAGCGCCCCTACTCGTGCCCGCACTGCCCGGCCCGCTTCCTGCACAGCTATG
spLeuLysAsnHisMetHisLeuHisThrGlyAspArgProTyrGluCysHisLeuCysHis
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
spLeuLysAsnHisMetHisLeuHisThrGlyAspArgProTyrGluCysHisLeuCysHis
ACCTCAAGAACCACATGCACCTGCACACGGGGGACCGGCCCTACGAGTGCCACCTGTGCCAC
LysAlaPheAlaLysGluAspHisLeuGlnArgHisLeuLysGlyGlnAsnCysLeuGluVa
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
LysAlaPheAlaLysGluAspHisLeuGlnArgHisLeuLysGlyGlnAsnCysLeuGluVa
AAGGCTTTCGCCAAGGAGGACCACCTGCAGCGCCACCTCAAGGGCCAGAACTGCCTGGAGGT
lArgThrArgArgArgArgLysAspAspAlaProProHisTyrProProProSerThrAlaA
|||||||||||||||||||||||||||||||||||||||||||||||||||||||
lArgThrArgArgArgArgLysAspAspAlaProProHisTyrProProProSerAlaThrT
GCGCACCCGGCGGCGCCGCAAGGACGATGCGCCACCCCACTATCCACCACCCTCCGCCACCA
laAlaSerProAlaGlyLeuAspLeuSerAsnGlyHisLeuAspThrPheArgLeuSerLeu
||||||||||||||||||||||||||||||||||||||| |||||||||||||||
hrProSerProAlaGlyLeuAspLeuSerAsnGlyHisLeuAspSerPheArgLeuSerLeu
CCCCTTCCCCGGCTGGTCTCGACCTCTCCAACGGCCACCTGGACTCCTTCCGCCTCTCTCTG
AlaArgPheTrpGluGlnSerAlaProThrGlyProProValSerThrProGlyProProAs
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
AlaArgPheTrpGluGlnSerAlaProThrGlyProProValSerThrProGlyProProAs
GCTCGATTCTGGGAGCAGTCAGCCCCAACCGGGCCCCCGGTCTCCACCCCGGGGCCTCCTGA
pAspAspGluGluGluGlyAlaProThrThrProGlnAlaGluGlyAlaMetGluSerSer
||||||| |||||||||||||||||||||||||||||||||||||||||||||||||||
pAspAspAspGluGluGlyAlaProThrThrProGlnAlaGluGlyAlaMetGluSerSer
TGACGACGACGAGGAGGGAGCACCCACCACACCCCAGGCTGAAGGTGCCATGGAGTCCTCT
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