| Basic information |
| Official Symbol | USP33 |
| Description | ubiquitin specific peptidase 33 |
| Other Aliases | VDU1 |
| Other Description | VHL-interacting deubiquitinating enzyme 1; deubiquitinating enzyme 33; pVHL-interacting deubiquitinating enzyme 1; ubiquitin carboxyl-terminal hydrolase 33; ubiquitin thioesterase 33; ubiquitin thiolesterase 33; ubiquitin-specific-processing protease 33 |
| Mutation type | Insert and frame-shift 30-31:N-K^A |
| Location | Scaffold000164_1:4009533 3957128 - |
| Wiki | Wikipedia GeneCard |
| Sequence |
| USP33 |
GTATTACCTCATTTGAAAGGCCTTGGAAAAGAGGAAAAATTTTCTAACAA AATGTCAGCTTTTCGAAATCATTGTCCACATTTGGATTCAGTTGGTGAAA TAACAAAAGAAGATTTAATACAAAAATCTCATGGTACTTGTCAGGATTGT AAAGTCAGAGGACCAAATCTTTGGGCATGCCTGGAGAGTAGATGTTCGTA TGTTGGCTGTGGTGAGTCACAAGTCGATCATAGCACCATACATTCTCAGG AGACAAAGCATTATCTAACTGTGAACCTTACCACTCTTCGAGTATGGTGT TATGCTTGCAGCAAAGAAGTATTTTTGGATAGGAAATTAGGAACTCAGCC TTCATTGCCTCATGTAAGACAACTTCACCAAACACAAGAAAACAGTGTCC AGGATTTTAAAATACCTAGTAATACAACATTAAAAACGCCTCTGGTTGCT GTATTTGATGATCTGGATATAGAAGTAGAAGAAGAAGATGAACTTAAAGC AAGAGGTCTAACAGGTTTGAAAAATATTGGAAATACTTGTTATATGAATG CAGCCTTGCAGGCTCTTTCTAATTGCCCACCCTTGACACAATTTTTCCTT GACTGTGGAGGACTAGCTCGGACAGATAAGAAACCAGCCATTTGTAAAAG TTATCTCAAACTAATGACAGAGCTGTGGCATAAAAGCAGGCCAGGATCTG TTGTGCCTACTAACCTGTTTCAAGGAATTAAAACTGTAAATCCAACATTT CGGGGGTATTCTCAGCAGGATGCTCAAGAATTTCTTCGATGTTTAATGGA TTTGCTTCATGAAGAATTGAAAGAGCAGGTCATGGAAGTAGAGGAAGATC CTCAAACCATAAGCACCGAGGAGGCAATGGAAGATGACAAGAGCCAGTCA GATGTAGATTTTCAGTCCTGTGAATCTTCTAGCAACAGTGATAAAGCAGA AAATGAAAGTAACTCTAGAGCCTTTTCTGAAGATAATAATGAAACAGCAA TGTTAATCCAGGATGATGAGAACAATTCAGAAATGTCAAAAGACTGGCAA AAAGAGAAGATGTACAATATGATCAATAAAGTGAACTCTGAAGGAGAATT AAATAAAGATAGAGACTCTGTGTCTGAACCAGTCGACTTGAACAACCAGG AAACTGTCAAAGTGCAAATACACAGTAGAGCTTCAGAATATATCACTGAT GTCCATTTGAATGACCTGTCTACATCACAGATGCTTCCATCAAATGAAGT TGTTAATCCACGTTTATCAGCAAGCCCTCCTAAATCAGGCAACTTGTGGC CAGGATTGGCACCCACACATAAAAAAGCTCAATCTGCATCTCCAAAGAGG AAAAAACAGCACAAGAAATACAGAAGTGTTATTTCTGACATATTTGATGG AACAATCATTAGTTCAGTACAGTGTCTGACTTGTGACAGGGTATCTGTAA CCCTCGAGACCTTTCAGGATCTGTCCTTGCCAATTCCTGGCAAGGAAGAC CTTGCTAAGCTGCACTCTTCAAGCCATCCAACTTCCATAGTCAAAGCAGG ATCATGTGGCGAAGCGTATGCTCCACAAGGGTGGATAGCTTTTTTCATGG AATATGTGAAGAGGTTTGTTGTCTCATGTGTCCCTAGCTGGTTTTGGGGT CCAATAGTAACCTTGCAAGATTGTCTTGCTGCTTTCTTCGCCAGAGATGA ACTAAAAGGTGACAATATGTACAGTTGTGAAAAATGTAAAAAGTTGAGGA ATGGAGTAAAGTTTTGTAAAGTACAAAAGTTTCCTGAGATTTTGTGTATC CACCTTAAAAGATTCAGACATGAACTGATGTTTTCCACCAAAATCAGTAC CCACGTTTCATTTCCGCTGGAAGGTCTGGACCTTCAGCCATTTCTTGCTA AGGACAGTCCAGCTCAAATTGTGACATACGATCTTCTGTCAGTCATTTGT CATCACGGAACTGCAAGCAGCGGACACTATATAGCCTACTGCCGAAACAA TTTAAATAATCTCTGGTATGAATTTGATGATCAGAGCGTCACTGAAGTTT CAGAATCTACTGTACAAAATGCAGAAGCTTATGTTCTTTTCTATAGGAAA AGTAGTGAAGAGGCACAAAAAGAGAGGCGAAGGATATCAAATTTGTTGAA CATAATGGAACCAAGCCTCCTTCAGTTTTATATTTCTCGACAGTGGCTAA ATAAATTTAAGACCTTTGCTGAGCCTGGTCCTATTTCAAATAATGACTTT CTCTGTATTCATGGAGGTGTTCCTCCACGAAAAGCTAGTTATATCGAAGA CCTAGTTTTGATGCTGCCGCAGAATATTTGGGATAACCTTTATAGCAGGT ATGGAGGAGGACCAGCTGTCAACCATCTATACATTTGTCATACTTGCCAA ATTGAGGCAGAGAAAATAGAAAAAAGAAGAAAAACTGAATTGGAAATTTT TATTCGGCTCAACAGAGCATTCCAAGAGGAGGACTCCCCAGCTACTTTTT ATTGCATTAGTATGCAGTGGTTTAGAGAATGGGAAAGTTTTGTGAAAGGT AAAGATGGAGATCCACCAGGTCCTATTGACAACACTAAAATTGCGGTCAC TAAATGTGGTAATGTGATGCTCAGGCAAGGAGCAGATTCTGGTCAAATTT CTGAAGAAACGTGGAGTTTTCTACAGTCTATATATGGTGGAGGGCCTGAA GTTATCCTGCGACCTCCAGTTGTTCATGTTGATCCTGACATACTACAAGC AGAAGAGAAAATTGAAGTAGAAACTCGGTCTTTA |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 942 | 15 | 942 | Insert and frame-shift 30-31:N-K^A |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
ValLeuProHisPheGluSerLeuGlyLysGlnGluLysIleProAsn-LysMetSerAl
|||||||||||| ||||||||| |||||| |||#|||||||||||
ValLeuProHisLeuLysGlyLeuGlyLysGluGluLysPheSerAsn#LysMetSerAl
GTATTACCTCATTTGAAAGGCCTTGGAAAAGAGGAAAAATTTTCTAACAAAAATGTCAGC
aPheArgAsnHisCysProHisLeuAspSerValGlyGluIleThrLysGluAspLeuIl
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
aPheArgAsnHisCysProHisLeuAspSerValGlyGluIleThrLysGluAspLeuIl
TTTTCGAAATCATTGTCCACATTTGGATTCAGTTGGTGAAATAACAAAAGAAGATTTAAT
eGlnLysSerLeu >>>> Target Intron 1 >>>> GlyThrCysGlnAspCys
|||||||||| 180 bp ||||||||||||||||||
eGlnLysSerHis++ ++GlyThrCysGlnAspCys
ACAAAAATCTCATgt agGGTACTTGTCAGGATTGT
LysValGlnGlyProAsnLeuTrpAlaCysLeuGlu >>>> Target Intron 2 >
|||||| ||||||||||||||||||||||||||| 427 bp
LysValArgGlyProAsnLeuTrpAlaCysLeuGlu-+
AAAGTCAGAGGACCAAATCTTTGGGCATGCCTGGAGct
>>> AsnArgCysSerTyrValGlyCysGlyGluSerGlnValAspHisSerThrIleH
||||||||||||||||||||||||||||||||||||||||||||||||||||
++SerArgCysSerTyrValGlyCysGlyGluSerGlnValAspHisSerThrIleH
agAGTAGATGTTCGTATGTTGGCTGTGGTGAGTCACAAGTCGATCATAGCACCATAC
isSerGln >>>> Target Intron 3 >>>> GluThrLysHisTyrLeuThrVa
|||||||| 1948 bp |||||||||||||||||||||||
isSerGln++ ++GluThrLysHisTyrLeuThrVa
ATTCTCAGgt agGAGACAAAGCATTATCTAACTGT
lAsnLeuThrThrLeuArgValTrpCysTyrAlaCysSerLysGluValPheLeuAspAr
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
lAsnLeuThrThrLeuArgValTrpCysTyrAlaCysSerLysGluValPheLeuAspAr
GAACCTTACCACTCTTCGAGTATGGTGTTATGCTTGCAGCAAAGAAGTATTTTTGGATAG
gLysLeuGlyThrGlnProSerLeuProHisValArgGlnProHisGlnIleGlnGluAs
|||||||||||||||||||||||||||||||||||||||| |||||| ||||||||
gLysLeuGlyThrGlnProSerLeuProHisValArgGlnLeuHisGlnThrGlnGluAs
GAAATTAGGAACTCAGCCTTCATTGCCTCATGTAAGACAACTTCACCAAACACAAGAAAA
nSerValGln >>>> Target Intron 4 >>>> AspPheLysIleProSerAsn
|||||||||| 6617 bp |||||||||||||||||||||
nSerValGln++ ++AspPheLysIleProSerAsn
CAGTGTCCAGgt agGATTTTAAAATACCTAGTAAT
ThrThrLeuLysThrProLeuValAlaValPheAspAspLeuAspIleGluAlaAspGlu
||||||||||||||||||||||||||||||||||||||||||||||||||| |||
ThrThrLeuLysThrProLeuValAlaValPheAspAspLeuAspIleGluValGluGlu
ACAACATTAAAAACGCCTCTGGTTGCTGTATTTGATGATCTGGATATAGAAGTAGAAGAA
GluAspGluLeuArgAlaArg{G} >>>> Target Intron 5 >>>> {ly}Leu
|||||||||||| ||||||{|} 737 bp {||}|||
GluAspGluLeuLysAlaArg{G}++ ++{ly}Leu
GAAGATGAACTTAAAGCAAGA{G}gt ag{GT}CTA
ThrGlyLeuLysAsnIleGlyAsnThrCysTyrMetAsnAlaAlaLeuGlnAlaLeuSer
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ThrGlyLeuLysAsnIleGlyAsnThrCysTyrMetAsnAlaAlaLeuGlnAlaLeuSer
ACAGGTTTGAAAAATATTGGAAATACTTGTTATATGAATGCAGCCTTGCAGGCTCTTTCT
Asn{Cy} >>>> Target Intron 6 >>>> {s}ProProLeuThrGlnPhePhe
|||{||} 5284 bp {|}|||||||||||||||||||||
Asn{Cy}++ ++{s}ProProLeuThrGlnPhePhe
AAT{TG}gt ag{C}CCACCCTTGACACAATTTTTC
LeuAspCysGlyGlyLeuAlaArgThrAspLysLysProAlaIleCysLysSerTyrLeu
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
LeuAspCysGlyGlyLeuAlaArgThrAspLysLysProAlaIleCysLysSerTyrLeu
CTTGACTGTGGAGGACTAGCTCGGACAGATAAGAAACCAGCCATTTGTAAAAGTTATCTC
LysLeuMetThrGluLeuTrpHisLysSer{Ar} >>>> Target Intron 7 >>>
||||||||||||||||||||||||||||||{||} 1557 bp
LysLeuMetThrGluLeuTrpHisLysSer{Ar}++
AAACTAATGACAGAGCTGTGGCATAAAAGC{AG}gt
> {g}ProGlySerValValProThrThrLeuPheGlnGlyIleLysThrValAsnPro
{|}||||||||||||||||||||| ||||||||||||||||||||||||||||||
++{g}ProGlySerValValProThrAsnLeuPheGlnGlyIleLysThrValAsnPro
ag{G}CCAGGATCTGTTGTGCCTACTAACCTGTTTCAAGGAATTAAAACTGTAAATCCA
ThrPheArgGlyTyrSerGlnGln >>>> Target Intron 8 >>>> AspAlaG
|||||||||||||||||||||||| 2089 bp |||||||
ThrPheArgGlyTyrSerGlnGln++ ++AspAlaG
ACATTTCGGGGGTATTCTCAGCAGgt agGATGCTC
lnGluPheLeuArgCysLeuMetAspLeuLeuHisGluGluLeuLysGluGlnValMetG
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
lnGluPheLeuArgCysLeuMetAspLeuLeuHisGluGluLeuLysGluGlnValMetG
AAGAATTTCTTCGATGTTTAATGGATTTGCTTCATGAAGAATTGAAAGAGCAGGTCATGG
luValGluGluAspProGlnThrIleThrThrGluGluThrMetGluGluAspLysSerG
|||||||||||||||||||||||||| ||||||||| |||||| ||||||||||
luValGluGluAspProGlnThrIleSerThrGluGluAlaMetGluAspAspLysSerG
AAGTAGAGGAAGATCCTCAAACCATAAGCACCGAGGAGGCAATGGAAGATGACAAGAGCC
lnSerAspValAspPheGlnSerCysGluSerCysSerAsnSerAspArgAlaGluAsnG
|||||||||||||||||||||||||||||||| |||||||||||| ||||||||||
lnSerAspValAspPheGlnSerCysGluSerSerSerAsnSerAspLysAlaGluAsnG
AGTCAGATGTAGATTTTCAGTCCTGTGAATCTTCTAGCAACAGTGATAAAGCAGAAAATG
luAsnGlySerArgCysPheSerGluAspAsnAsnGluThrThrMetLeuIleGlnAspA
|| |||||| |||||||||||||||||||||||| ||||||||||||||||
luSerAsnSerArgAlaPheSerGluAspAsnAsnGluThrAlaMetLeuIleGlnAspA
AAAGTAACTCTAGAGCCTTTTCTGAAGATAATAATGAAACAGCAATGTTAATCCAGGATG
spGluAsnAsnSerGluMetSerLysAspTrpGlnLysGluLysMetCysAsnLysIleA
||||||||||||||||||||||||||||||||||||||||||||||| ||| ||||
spGluAsnAsnSerGluMetSerLysAspTrpGlnLysGluLysMetTyrAsnMetIleA
ATGAGAACAATTCAGAAATGTCAAAAGACTGGCAAAAAGAGAAGATGTACAATATGATCA
snLysValAsnSerGluGlyGluPheAspLysAspArgAspSerIleSerGluThrValA
||||||||||||||||||||||| ||||||||||||||| |||||| ||||
snLysValAsnSerGluGlyGluLeuAsnLysAspArgAspSerValSerGluProValA
ATAAAGTGAACTCTGAAGGAGAATTAAATAAAGATAGAGACTCTGTGTCTGAACCAGTCG
spLeuAsnAsnGlnGluThrValLysValGlnIleHisSerArgAlaSer{G} >>>>
||||||||||||||||||||||||||||||||||||||||||||||||||{|}
spLeuAsnAsnGlnGluThrValLysValGlnIleHisSerArgAlaSer{G}++
ACTTGAACAACCAGGAAACTGTCAAAGTGCAAATACACAGTAGAGCTTCA{G}gt
Target Intron 9 >>>> {lu}TyrIleThrAspValHisSerAsnAspLeuSerT
2810 bp {||}|||||||||||||||||| |||||||||||||
++{lu}TyrIleThrAspValHisLeuAsnAspLeuSerT
ag{AA}TATATCACTGATGTCCATTTGAATGACCTGTCTA
hrProGlnIleLeuProSerAsnGluGlyValAsnProArgLeuSerAlaSerProProL
|| ||| ||||||||||||||| |||||||||||||||||||||||||||||||
hrSerGlnMetLeuProSerAsnGluValValAsnProArgLeuSerAlaSerProProL
CATCACAGATGCTTCCATCAAATGAAGTTGTTAATCCACGTTTATCAGCAAGCCCTCCTA
ysSerGlyAsnLeuTrpProGlyLeuAlaProProHisLysLys{A} >>>> Target
|||||||||||||||||||||||||||||||| |||||||||{|} 2
ysSerGlyAsnLeuTrpProGlyLeuAlaProThrHisLysLys{A}++
AATCAGGCAACTTGTGGCCAGGATTGGCACCCACACATAAAAAA{G}gt
Intron 10 >>>> {la}GlnSerAlaSerProLysArgLysLysGlnHisLysLys
846 bp {||}|||||||||||||||||||||||||||||||||||||||
++{la}GlnSerAlaSerProLysArgLysLysGlnHisLysLys
ag{CT}CAATCTGCATCTCCAAAGAGGAAAAAACAGCACAAGAAA
TyrArgSerValIleSerAspIlePheAspGlyThrIleIleSerSerValGlnCysLeu
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
TyrArgSerValIleSerAspIlePheAspGlyThrIleIleSerSerValGlnCysLeu
TACAGAAGTGTTATTTCTGACATATTTGATGGAACAATCATTAGTTCAGTACAGTGTCTG
ThrCysAspArg >>>> Target Intron 11 >>>> ValSerValThrLeuGlu
|||||||||||| 2130 bp ||||||||||||||||||
ThrCysAspArg++ ++ValSerValThrLeuGlu
ACTTGTGACAGGgt agGTATCTGTAACCCTCGAG
ThrPheGlnAspLeuSerLeuProIleProGlyLysGluAspLeuAlaLysLeuHisSer
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ThrPheGlnAspLeuSerLeuProIleProGlyLysGluAspLeuAlaLysLeuHisSer
ACCTTTCAGGATCTGTCCTTGCCAATTCCTGGCAAGGAAGACCTTGCTAAGCTGCACTCT
SerSerHisProThrSerIleValLysAlaGlySerCysGlyGluAlaTyrAlaProGln
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
SerSerHisProThrSerIleValLysAlaGlySerCysGlyGluAlaTyrAlaProGln
TCAAGCCATCCAACTTCCATAGTCAAAGCAGGATCATGTGGCGAAGCGTATGCTCCACAA
GlyTrpIleAlaPhePheMetGluTyrValLys{Ar} >>>> Target Intron 12
|||||||||||||||||||||||||||||||||{||} 98 bp
GlyTrpIleAlaPhePheMetGluTyrValLys{Ar}++
GGGTGGATAGCTTTTTTCATGGAATATGTGAAG{AG}gt
>>>> {g}PheValValSerCysValProSerTrpPheTrpGlyProValValThrLe
{|}||||||||||||||||||||||||||||||||||||||| ||||||||
++{g}PheValValSerCysValProSerTrpPheTrpGlyProIleValThrLe
ag{G}TTTGTTGTCTCATGTGTCCCTAGCTGGTTTTGGGGTCCAATAGTAACCTT
uGlnAspCysLeuAlaAlaPhePheAlaArgAspGluLeuLys{G} >>>> Target
|||||||||||||||||||||||||||||||||||||||||||{|} 10
uGlnAspCysLeuAlaAlaPhePheAlaArgAspGluLeuLys{G}++
GCAAGATTGTCTTGCTGCTTTCTTCGCCAGAGATGAACTAAAA{G}gt
Intron 13 >>>> {ly}AspAsnMetTyrSerCysGluLysCysLys{Ly} >>>>
58 bp {||}||||||||||||||||||||||||||||||{||}
++{ly}AspAsnMetTyrSerCysGluLysCysLys{Ly}++
ag{GT}GACAATATGTACAGTTGTGAAAAATGTAAA{AA}gt
Target Intron 14 >>>> {s}LeuArgAsnGlyValLysPheCysLysValGln
2831 bp {|}|||||||||||||||||||||||||||||||||
++{s}LeuArgAsnGlyValLysPheCysLysValGln
ag{G}TTGAGGAATGGAGTAAAGTTTTGTAAAGTACAA
AsnPheProGlu >>>> Target Intron 15 >>>> IleLeuCysIleHisLeu
||||||||| 1335 bp ||||||||||||||||||
LysPheProGlu++ ++IleLeuCysIleHisLeu
AAGTTTCCTGAGgt agATTTTGTGTATCCACCTT
LysArgPheArgHisGluLeuMetPheSerThrLysIleSerThrHisValSerPhePro
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
LysArgPheArgHisGluLeuMetPheSerThrLysIleSerThrHisValSerPhePro
AAAAGATTCAGACATGAACTGATGTTTTCCACCAAAATCAGTACCCACGTTTCATTTCCG
LeuGluGlyLeuAspLeuGlnProPheLeuAlaLysAspSerProAlaGlnIleValThr
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
LeuGluGlyLeuAspLeuGlnProPheLeuAlaLysAspSerProAlaGlnIleValThr
CTGGAAGGTCTGGACCTTCAGCCATTTCTTGCTAAGGACAGTCCAGCTCAAATTGTGACA
TyrAspLeuLeuSerValIleCysHisHisGlyThrAlaSer{S} >>>> Target I
||||||||||||||||||||||||||||||||||||||||||{|} 209
TyrAspLeuLeuSerValIleCysHisHisGlyThrAlaSer{S}++
TACGATCTTCTGTCAGTCATTTGTCATCACGGAACTGCAAGC{A}gt
ntron 16 >>>> {er}GlyHisTyrIleAlaTyrCysArgAsnAsnLeuAsnAsnLe
7 bp {||}|||||||||||||||||||||||||||||||||||||||||
++{er}GlyHisTyrIleAlaTyrCysArgAsnAsnLeuAsnAsnLe
ag{GC}GGACACTATATAGCCTACTGCCGAAACAATTTAAATAATCT
uTrpTyrGluPheAspAspGlnSerValThrGluValSerGluSerThrValGlnAsnAl
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
uTrpTyrGluPheAspAspGlnSerValThrGluValSerGluSerThrValGlnAsnAl
CTGGTATGAATTTGATGATCAGAGCGTCACTGAAGTTTCAGAATCTACTGTACAAAATGC
aGluAlaTyrValLeuPheTyr{Ar} >>>> Target Intron 17 >>>> {g}L
||||||||||||||||||||||{||} 666 bp {|}|
aGluAlaTyrValLeuPheTyr{Ar}++ ++{g}L
AGAAGCTTATGTTCTTTTCTAT{AG}gt ag{G}A
ysSerSerGluGluAlaGlnLysGluArgArgArgIleSerAsnLeuLeuAsnIleMetG
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ysSerSerGluGluAlaGlnLysGluArgArgArgIleSerAsnLeuLeuAsnIleMetG
AAAGTAGTGAAGAGGCACAAAAAGAGAGGCGAAGGATATCAAATTTGTTGAACATAATGG
luProSerLeuLeuGlnPheTyrIleSerArgGlnTrpLeuAsnLysPheLysThrPheA
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
luProSerLeuLeuGlnPheTyrIleSerArgGlnTrpLeuAsnLysPheLysThrPheA
AACCAAGCCTCCTTCAGTTTTATATTTCTCGACAGTGGCTAAATAAATTTAAGACCTTTG
laGluProGlyProIleSerAsnAsnAspPheLeuCysIleHisGly{G} >>>> Tar
|||||||||||||||||||||||||||||||||||||||||||||||{|}
laGluProGlyProIleSerAsnAsnAspPheLeuCysIleHisGly{G}++
CTGAGCCTGGTCCTATTTCAAATAATGACTTTCTCTGTATTCATGGA{G}gt
get Intron 18 >>>> {ly}ValProProArgLysAlaGlyTyrIleGluAspLeu
879 bp {||}|||||||||||||||||| |||||||||||||||
++{ly}ValProProArgLysAlaSerTyrIleGluAspLeu
ag{GT}GTTCCTCCACGAAAAGCTAGTTATATCGAAGACCTA
ValLeuMetLeuProGlnAsnIleTrpAspAsnLeuTyrSer{Ar} >>>> Target
||||||||||||||||||||||||||||||||||||||||||{||} 20
ValLeuMetLeuProGlnAsnIleTrpAspAsnLeuTyrSer{Ar}++
GTTTTGATGCTGCCGCAGAATATTTGGGATAACCTTTATAGC{AG}gt
Intron 19 >>>> {g}TyrGlyGlyGlyProAlaValAsnHisLeuTyrIleCysHi
13 bp {|}|||||||||||||||||||||||||||||||||||||||||
++{g}TyrGlyGlyGlyProAlaValAsnHisLeuTyrIleCysHi
ag{G}TATGGAGGAGGACCAGCTGTCAACCATCTATACATTTGTCA
sThrCysGlnIleGluAlaGluLysIleGluLysArgArgLysThrGluLeuGluIlePh
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
sThrCysGlnIleGluAlaGluLysIleGluLysArgArgLysThrGluLeuGluIlePh
TACTTGCCAAATTGAGGCAGAGAAAATAGAAAAAAGAAGAAAAACTGAATTGGAAATTTT
eIleArg >>>> Target Intron 20 >>>> LeuAsnArgAlaPheGlnLysGl
||||||| 10514 bp |||||||||||||||||| ||
eIleArg++ ++LeuAsnArgAlaPheGlnGluGl
TATTCGGgt agCTCAACAGAGCATTCCAAGAGGA
uAspSerProAlaThrPheTyrCysIleSerMetGlnTrpPheArgGluTrpGluSerPh
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
uAspSerProAlaThrPheTyrCysIleSerMetGlnTrpPheArgGluTrpGluSerPh
GGACTCCCCAGCTACTTTTTATTGCATTAGTATGCAGTGGTTTAGAGAATGGGAAAGTTT
eValLysGlyLysAspGly{A} >>>> Target Intron 21 >>>> {sp}ProP
|||||||||||||||||||{|} 894 bp {||}||||
eValLysGlyLysAspGly{A}++ ++{sp}ProP
TGTGAAAGGTAAAGATGGA{G}gt ag{AT}CCAC
roGlyProIleAspAsnThrLysIleAlaValThrLysCysGlyAsnValMetLeuArgG
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
roGlyProIleAspAsnThrLysIleAlaValThrLysCysGlyAsnValMetLeuArgG
CAGGTCCTATTGACAACACTAAAATTGCGGTCACTAAATGTGGTAATGTGATGCTCAGGC
ln{G} >>>> Target Intron 22 >>>> {ly}AlaAspSerGlyGlnIleSer
||{|} 611 bp {||}|||||||||||||||||||||
ln{G}++ ++{ly}AlaAspSerGlyGlnIleSer
AA{G}gt ag{GA}GCAGATTCTGGTCAAATTTCT
GluGluThrTrpAsnPheLeuGlnSerIleTyrGlyGlyGlyProGluValIleLeuArg
|||||||||||| |||||||||||||||||||||||||||||||||||||||||||||
GluGluThrTrpSerPheLeuGlnSerIleTyrGlyGlyGlyProGluValIleLeuArg
GAAGAAACGTGGAGTTTTCTACAGTCTATATATGGTGGAGGGCCTGAAGTTATCCTGCGA
ProProValValHisValAspProAspIleLeuGlnAlaGluGluLysIleGluValGlu
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ProProValValHisValAspProAspIleLeuGlnAlaGluGluLysIleGluValGlu
CCTCCAGTTGTTCATGTTGATCCTGACATACTACAAGCAGAAGAGAAAATTGAAGTAGAA
ThrArgSerLeu
||||||||||||
ThrArgSerLeu
ACTCGGTCTTTA
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