| Basic information |
| Official Symbol | TNFSF13B |
| Description | tumor necrosis factor (ligand) superfamily, member 13b |
| Other Aliases | RP11-153I24.1, BAFF, BLYS, CD257, DTL, TALL-1, TALL1, THANK, TNFSF20, ZTNF4 |
| Other Description | ApoL related ligand TALL-1; B-cell-activating factor; B-lymphocyte stimulator; Delta4 BAFF; TNF and ApoL-related leukocyte expressed ligand 1; TNF homolog that activates apoptosis; delta BAFF; dendritic cell-derived TNF-like molecule; tumor necrosis factor (ligand) superfamily, member 20; tumor necrosis factor ligand superfamily member 13B; tumor necrosis factor-like protein ZTNF4 |
| Mutation type | Delete and frame-shift 20:E->AA |
| Location | Scaffold000644_1:3003242 3061092 + |
| Wiki | Wikipedia GeneCard |
| Sequence |
| TNFSF13B |
GACTCCACAGAAAGGGAGCAGCCACGCCTTCCTCCTGGCCCTAGGAAAAGGAAGAGATGA AATCAGTCACTCAAGACTGCTTGCAGCTGATAGCAGACAGCGACACGCCGACTATACGGA AATCTTTCACATTTGTTCCATGGCTTCTCAGCTTTAAAAGAGGAAGTGCCCTAGAAGAAA AAGAGAATAAAATTTTGGTCAAAGAAACCGGTTACTTCTTTATATATGGTCAGGTTTTGT ACACCGGTAATACCTTTGCCATGGGACACCTAATACAGAGGAAAAAAGTCCATGTCTTTG GGGATGAATTGAGTCTGGTGACTTTGTTCCGATGTATTCAAAATATGCCTGAAACTCTAC CCAATAATTCCTGTTATTCAGCTATTGCCAAGTTGGAAGAAGGAGATGAACTTCAACTTG CAATACCACGAGAAAACGCTCAAATATCCCAGGACGGAGACGGCACATTTTTCGGCGCTT TGAAGCTGCTG |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 285 | 3 | 285 | Delete and frame-shift 20:E->AA |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
AspSerThrGluArgGluGlnSerArgLeuThrSerCysLeuLysLysArgGluGluMetLys
||||||||||||||||||||| |||||| |||||| |||||||||
AspSerThrGluArgGluGlnProArgLeuProProGlyProArgLysArg---GluMetLys
GACTCCACAGAAAGGGAGCAGCCACGCCTTCCTCCTGGCCCTAGGAAAAGGAA#GAGATGAAA
ThrValThrGlnAspCysLeuGlnLeuIleAlaAspSerGluThrProThrIleGlnLys
|||||||||||||||||||||||||||||||||||| |||||||||||| |||
SerValThrGlnAspCysLeuGlnLeuIleAlaAspSerAspThrProThrIleArgLys
TCAGTCACTCAAGACTGCTTGCAGCTGATAGCAGACAGCGACACGCCGACTATACGGAAA
{G} >>>> Target Intron 1 >>>> {ly}SerTyrThrPheValProTrpLeu
{|} 16391 bp {||}||| ||||||||||||||||||
{G}++ ++{ly}SerPheThrPheValProTrpLeu
{G}gt ag{GT}TCTTTCACATTTGTTCCATGGCTT
LeuSerPheLysArgGlySerAlaLeuGluGluLysGluAsnLysIleLeuValLysGlu
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
LeuSerPheLysArgGlySerAlaLeuGluGluLysGluAsnLysIleLeuValLysGlu
CTCAGCTTTAAAAGAGGAAGTGCCCTAGAAGAAAAAGAGAATAAAATTTTGGTCAAAGAA
ThrGlyTyrPhePheIleTyrGlyGln >>>> Target Intron 2 >>>> ValL
||||||||||||||||||||||||||| 86 bp ||||
ThrGlyTyrPhePheIleTyrGlyGln++ ++ValL
ACCGGTTACTTCTTTATATATGGTCAGgt agGTTT
euTyrThrAspLysThrTyrAlaMetGlyHisLeuIleGlnArgLysLysValHisValP
|||||||| ||| ||||||||||||||||||||||||||||||||||||||||
euTyrThrGlyAsnThrPheAlaMetGlyHisLeuIleGlnArgLysLysValHisValP
TGTACACCGGTAATACCTTTGCCATGGGACACCTAATACAGAGGAAAAAAGTCCATGTCT
heGlyAspGluLeuSerLeuValThrLeuPheArgCysIleGlnAsnMetProGluThrL
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
heGlyAspGluLeuSerLeuValThrLeuPheArgCysIleGlnAsnMetProGluThrL
TTGGGGATGAATTGAGTCTGGTGACTTTGTTCCGATGTATTCAAAATATGCCTGAAACTC
euProAsnAsnSerCysTyrSerAla{G} >>>> Target Intron 3 >>>> {l
||||||||||||||||||||||||||{|} 5486 bp {|
euProAsnAsnSerCysTyrSerAla{G}++ ++{l
TACCCAATAATTCCTGTTATTCAGCT{G}gt ag{G
y}IleAlaLysLeuGluGluGlyAspGluLeuGlnLeuAlaIleProArgGluAsnAlaG
|}||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
y}IleAlaLysLeuGluGluGlyAspGluLeuGlnLeuAlaIleProArgGluAsnAlaG
C}ATTGCCAAGTTGGAAGAAGGAGATGAACTTCAACTTGCAATACCACGAGAAAACGCTC
lnIleSerLeuAspGlyAspValThrPhePheGlyAlaLeuLysLeuLeu
|||||||| ||||||||| |||||||||||||||||||||||||||
lnIleSerGlnAspGlyAspGlyThrPhePheGlyAlaLeuLysLeuLeu
AAATATCCCAGGACGGAGACGGCACATTTTTCGGCGCTTTGAAGCTGCTG
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