| Basic information |
| Official Symbol | SLC38A5 |
| Description | solute carrier family 38, member 5 |
| Other Aliases | PP7194, JM24, SN2, SNAT5, pp7194 |
| Other Description | sodium-coupled neutral amino acid transporter 5; system N transporter 2 |
| Mutation type | Insert and frame-shift 30-31:R-G^GG, Insert and frame-shift 72-73:A-M^CC, premature termination 250:Q->TAG, premature termination 313:Y->TAG, premature termination 394:V->TAG |
| Location | Scaffold143793_1:237995 250262 + |
| Wiki | Wikipedia GeneCard |
| Sequence |
| SLC38A5 |
GAATGCAAGGGCTTCCTGCCCAGCCGTGGTCCTGCTCCTGGGAGGAAACC GGTCCAGTTCATGGATTTCGAGGGGAAAACATCATTTGCAATGTCAGTGT TCAACCTCAGCAATGCTATCATGGGCAGTGGCATCATAATGGCCCACACA GGGGTGCTCTTCTTCCTGGCCCTGCTGCTGTGCATTACACTTCTGTCTTC ATACTCTATCCACCTCCTGCTGACTTGTGCTGGTGTTGTAGGCATCCGAG CCTATGAGCAGCTGGGACAGAAGGCATTTGGACCTGCAGGGAAGGCAGTA GTGGCTGGGTTCATCTGTCTGCATAATGTTGGGGCCATGTCCAGTTACCT GTTCATCATCAAATCTGAACTCCCCCTGGTTATTGGCACCTTCCTGCACA TGGACCCAAGGGGGGACTGGTTCTTGAAGGGAAACCTCCTCATCATCATT GTCAGTGTGCTTGTCATTCTGCCTCTGGCCCTCATGAAATACTTGGGCTA CCTGGGGTATACCAGTGGTCTCTCTCTGACCTGCATGCTGTTTTTCCTCA TTGTGCTCATCTATAAGAAGTTCCAGCTTGGCTATGCTGTTGGCCGCAAT GAGACAGCAATGGAGAGTGAATCCTCACCAGACCTCTCCGCCCAGGGGCT CAACAGTAGCTGTGAGGCCTAGTTGTTCACAGTAGACTCTCAGATGTCTT ACACAGTGCCCATTATGGCTTTTGCCTTTATCTGCCACTCTGAGGTGCTG CCCATCTACACAGAGCTCTGCCGGCCCTCCCAGCACAGGATGCAGGCTGT GGCCAACGTGTCCATTGGGGCCATGTTCTGCAGGTATGGGCTCACAGCAA CCTTTGGATAGCTCACTTTCTATAGCAGCATGGAGACAGAGATGCTGCTC ATGTACAGCAAGGAGGATGTGCTCATCCTCTGCGTGCGCCTGGCCATGCT GCTTGCCATGACCCTCACTGTACCACTTGTGCTGTTCCCTATCTGCTGGG CCCTGCAGCAGCTGTTTCTCCCTGCTTGTTTTGGGCAATGTCCTTGTCAT CTGTGTTCCAACCATCTGGGACATCTTTGGGGTTATTGTTGTTCTCAAAC TTAGGTTGACTTCTGTCCCTCCTTTCTGTCTCTAGGGTTGACCTCAGTCG CCAGCCTCATCTTCATCCTTCCCAGTGTCTTCTACCTCCGCATTGTACCC TCTGAGGTGGAGCCCTTCTTTTCCTGGCCCAAGATCCGGGCCCTGTGTTT TGGCATCCTGGGGGTCCTCTTCATGGCCATCAGTCTAGGCTTTATGTTTG CCAACTGGGTCACAGGCCAGAGCCATGTGTTTGGACAC |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 472 | 22 | 472 | Insert and frame-shift 30-31:R-G^GG, Insert and frame-shift 72-73:A-M^CC, Premature termination 250:Q->TAG, Premature termination 313:Y->TAG, Premature termination 394:V->TAG |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
GluArgGluGlyPheLeuProSerArg--GlyProAlaProGlySerLysProValGlnP
||| ||||||||||||||||||##||||||||||||||| |||||||||||||
GluCysLysGlyPheLeuProSerArg##GlyProAlaProGlyArgLysProValGlnP
GAATGCAAGGGCTTCCTGCCCAGCCGTGGGGTCCTGCTCCTGGGAGGAAACCGGTCCAGT
heMetAsp >>>> Target Intron 1 >>>> PheGluGlyLysThrSerPheGl
|||||||| 520 bp |||||||||||||||||||||
heMetAsp++ ++PheGluGlyLysThrSerPheAl
TCATGGATgt agTTCGAGGGGAAAACATCATTTGC
yMetSerValPheAsnLeuSerAsnAlaIleMetGlySerGlyIleLeuGlyLeuAlaTy
|||||||||||||||||||||||||||||||||||||||||||||
aMetSerValPheAsnLeuSerAsnAlaIleMetGlySerGlyIleIle-----------
AATGTCAGTGTTCAACCTCAGCAATGCTATCATGGGCAGTGGCATCATA-----------
rAla--MetAlaHisThrGlyValIlePhePhe{Le} >>>> Target Intron 2
##|||||||||||||||||| ||||||{||} 89 bp
----##MetAlaHisThrGlyValLeuPhePhe{Le}++
----CCATGGCCCACACAGGGGTGCTCTTCTTC{CT}gt
>>>> {u}AlaLeuLeuLeuCysIleAlaLeuLeuSerSerTyrSerIleHisLeuLeu
{|}|||||||||||||||||| ||||||||||||||||||||||||||||||
++{u}AlaLeuLeuLeuCysIleThrLeuLeuSerSerTyrSerIleHisLeuLeu
ag{G}GCCCTGCTGCTGTGCATTACACTTCTGTCTTCATACTCTATCCACCTCCTG
LeuThrCysAlaGlyIleAla{G} >>>> Target Intron 3 >>>> {ly}Ile
||||||||||||||| {|} 688 bp {||}|||
LeuThrCysAlaGlyValVal{G}++ ++{ly}Ile
CTGACTTGTGCTGGTGTTGTA{G}gt ag{GC}ATC
ArgAlaTyrGluGlnLeuGlyGlnArgAlaPheGlyProAlaGlyLysValValValAla
|||||||||||||||||||||||| ||||||||||||||||||||| |||||||||
ArgAlaTyrGluGlnLeuGlyGlnLysAlaPheGlyProAlaGlyLysAlaValValAla
CGAGCCTATGAGCAGCTGGGACAGAAGGCATTTGGACCTGCAGGGAAGGCAGTAGTGGCT
ThrValIleCysLeuHisAsnValGly{A} >>>> Target Intron 4 >>>> {
|||||||||||||||||||||{|} 136 bp {
GlyPheIleCysLeuHisAsnValGly{A}++ ++{
GGGTTCATCTGTCTGCATAATGTTGGG{G}gt ag{
la}MetSerSerTyrLeuPheIleIleLysSerGluLeuProLeuValIleGlyThrPhe
||}|||||||||||||||||||||||||||||||||||||||||||||||||||||||||
la}MetSerSerTyrLeuPheIleIleLysSerGluLeuProLeuValIleGlyThrPhe
CC}ATGTCCAGTTACCTGTTCATCATCAAATCTGAACTCCCCCTGGTTATTGGCACCTTC
LeuTyrMetAspProGlu{G} >>>> Target Intron 5 >>>> {ly}AspTrp
||| ||||||||| {|} 5310 bp {||}||||||
LeuHisMetAspProArg{G}++ --{ly}AspTrp
CTGCACATGGACCCAAGG{G}gt ta{GG}GACTGG
PheLeuLysGlyAsnLeuLeuIleIleIleValSerValLeuIleIleLeuProLeuAla
|||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
PheLeuLysGlyAsnLeuLeuIleIleIleValSerValLeuValIleLeuProLeuAla
TTCTTGAAGGGAAACCTCCTCATCATCATTGTCAGTGTGCTTGTCATTCTGCCTCTGGCC
LeuMetLysHisLeu{G} >>>> Target Intron 6 >>>> {ly}TyrLeuGly
||||||||| |||{|} 856 bp {||}|||||||||
LeuMetLysTyrLeu{G}++ ++{ly}TyrLeuGly
CTCATGAAATACTTG{G}gt ag{GC}TACCTGGGG
TyrThrSerGlyLeuSerLeuThrCysMetLeuPhePheLeuValSer >>>> Targe
||||||||||||||||||||||||||||||||||||||||||
TyrThrSerGlyLeuSerLeuThrCysMetLeuPhePheLeuIleVal++
TATACCAGTGGTCTCTCTCTGACCTGCATGCTGTTTTTCCTCATTGTGgt
t Intron 7 >>>> ValIleTyrLysLysPheGlnLeuGlyCysAlaIleGlyHisA
104 bp |||||||||||||||||||||||| ||| ||| |
++LeuIleTyrLysLysPheGlnLeuGlyTyrAlaValGlyArgA
agCTCATCTATAAGAAGTTCCAGCTTGGCTATGCTGTTGGCCGCA
snGluThrAlaMetGluSerGluAlaLeuValGlyLeuProSerGlnGlyLeuAsnSerS
||||||||||||||||||||||| ||| ||||||||||||||||
snGluThrAlaMetGluSerGluSerSerProAspLeuSerAlaGlnGlyLeuAsnSerS
ATGAGACAGCAATGGAGAGTGAATCCTCACCAGACCTCTCCGCCCAGGGGCTCAACAGTA
erCysGluAlaGlnMetPheThrValAspSerGln >>>> Target Intron 8 >>
||||||||||| |||||||||||||||||| 206 bp
erCysGluAla***LeuPheThrValAspSerGln++
GCTGTGAGGCCTAGTTGTTCACAGTAGACTCTCAGgt
>> MetSerTyrThrValProIleMetAlaPheAlaPheValCysHisProGluValLe
|||||||||||||||||||||||||||||||||||| |||||| ||||||||
++MetSerTyrThrValProIleMetAlaPheAlaPheIleCysHisSerGluValLe
agATGTCTTACACAGTGCCCATTATGGCTTTTGCCTTTATCTGCCACTCTGAGGTGCT
uProIleTyrThrGluLeuCys{Ar} >>>> Target Intron 9 >>>> {g}Pr
||||||||||||||||||||||{||} 1056 bp {|}||
uProIleTyrThrGluLeuCys{Ar}++ ++{g}Pr
GCCCATCTACACAGAGCTCTGC{CG}gt ag{G}CC
oSerLysArgArgMetGlnAlaValAlaAsnValSerIleGlyAlaMetPheCysMetTy
|||| ||||||||||||||||||||||||||||||||||||||||||||| ||
oSerGlnHisArgMetGlnAlaValAlaAsnValSerIleGlyAlaMetPheCysArgTy
CTCCCAGCACAGGATGCAGGCTGTGGCCAACGTGTCCATTGGGGCCATGTTCTGCAGGTA
rGlyLeuThrAlaThrPheGlyTyrLeuThrPheTyr{S} >>>> Target Intron
|||||||||||||||||||||| ||||||||||||{|} 222 bp
rGlyLeuThrAlaThrPheGly***LeuThrPheTyr{S}++
TGGGCTCACAGCAACCTTTGGATAGCTCACTTTCTAT{A}gt
10 >>>> {er}SerValLysAlaGluMetLeuHisMetTyrSerGlnLysAspProL
{||}||| ||||||||| ||||||||| ||| |
++{er}SerMetGluThrGluMetLeuLeuMetTyrSerLysGluAspValL
ag{GC}AGCATGGAGACAGAGATGCTGCTCATGTACAGCAAGGAGGATGTGC
euIleLeuCysValArgLeuAlaValLeuLeuAlaValThrLeuThrValProValValL
||||||||||||||||||||||| ||||||||| ||||||||||||||| ||||
euIleLeuCysValArgLeuAlaMetLeuLeuAlaMetThrLeuThrValProLeuValL
TCATCCTCTGCGTGCGCCTGGCCATGCTGCTTGCCATGACCCTCACTGTACCACTTGTGC
euPhePro >>>> Target Intron 11 >>>> IleArgArgAlaLeuGlnGlnL
|||||||| 1211 bp ||| |||||||||||||
euPhePro++ ++IleCysTrpAlaLeuGlnGlnL
TGTTCCCTgt agATCTGCTGGGCCCTGCAGCAGC
euLeuPheProGlyLysAlaPheSerTrpProArgHisValAlaIleAlaLeuIleLeuL
|| ||| ||| |||
euPheLeuProAlaCysPheGlyGlnCysProCysHisLeuCysSerAsnHisLeuGlyH
TGTTTCTCCCTGCTTGTTTTGGGCAATGTCCTTGTCATCTGTGTTCCAACCATCTGGGAC
euValLeuValAsn{Va} >>>> Target Intron 12 >>>> {l}LeuValIle
{ } 45 bp { }
isLeuTrpGlyTyr{Cy}++ --{s}CysSerGln
ATCTTTGGGGTTAT{TG}gt ct{T}TGTTCTCAA
CysValProThrIleArgAspIlePheGlyValIleGlySerThrSerAlaProSerLeu
||| ||| |||||| ||||||
Thr***ValAspPheCysProSerPheLeuSerLeuGlyLeuThrSerValAlaSerLeu
ACTTAGGTTGACTTCTGTCCCTCCTTTCTGTCTCTAGGGTTGACCTCAGTCGCCAGCCTC
IlePheIleLeuProSerIlePheTyrLeuArgIleValProSerGluValGluProPhe
|||||||||||||||||| |||||||||||||||||||||||||||||||||||||||
IlePheIleLeuProSerValPheTyrLeuArgIleValProSerGluValGluProPhe
ATCTTCATCCTTCCCAGTGTCTTCTACCTCCGCATTGTACCCTCTGAGGTGGAGCCCTTC
LeuSerTrpProLysIleGln >>>> Target Intron 13 >>>> AlaLeuCys
||||||||||||||| 483 bp |||||||||
PheSerTrpProLysIleArg++ ++AlaLeuCys
TTTTCCTGGCCCAAGATCCGGgt agGCCCTGTGT
PheGlyValLeuGlyValLeuPheMetAlaValSerLeuGlyPheMetPheAlaAsnTrp
|||||| ||||||||||||||||||||| |||||||||||||||||||||||||||
PheGlyIleLeuGlyValLeuPheMetAlaIleSerLeuGlyPheMetPheAlaAsnTrp
TTTGGCATCCTGGGGGTCCTCTTCATGGCCATCAGTCTAGGCTTTATGTTTGCCAACTGG
AlaThrGlyGlnSerArgMetSerGlyHis
|||||||||||| ||||||
ValThrGlyGlnSerHisValPheGlyHis
GTCACAGGCCAGAGCCATGTGTTTGGACAC
//
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