| Basic information |
| Official Symbol | RYBP |
| Description | RING1 and YY1 binding protein |
| Other Aliases | AAP1, DEDAF, YEAF1 |
| Other Description | APAP-1; DED-associated factor; RING1 and YY1-binding protein; YY1 and E4TF1 associated factor 1; YY1 and E4TF1-associated factor 1; apoptin-associating protein 1; death effector domain-associated factor; ring1 interactor RYBP |
| Mutation type | Insert and frame-shift 61-62:L-D^C, Insert and frame-shift 78-79:S-P^C |
| Location | Scaffold000570_1:590915 671304 + |
| Wiki | Wikipedia GeneCard |
| Sequence |
| RYBP |
CTTCCTGCGCCCGCCGCGGCCCTTCCCGGGGGCGCCGCCGCCGCCGCCGT CGCCGTCGCCTGGTGTGCGAGGCAGTCCGGCCCGGCCCCGGGTGCCGGTG GGGGAGCCCAGTTTCCTGCCCCGTTCCCTCTTCCAGCCCCCGAAGAGGGT AGGTGGGTGGTCGCCCGAGCGAAGTTTCCAGCAGATTTCGGCGAAATTAC GACGGCTCACCAGCGCCTGTGTTTTGCTGTCTCTCCCCCTTTTTCCTGTT CCCTGTCTGTTCCCTCCCCTTTCTCCCACTCCCCACTCCTCCGAAGGCCA AAAAGACAAGCGAAACCTGCGGCAGACGAAGGCTTTTGGGATTGTAGCGT CTGCACCTTCAGGAACAGCGCCGAAGCCTTTAAATGCAGCATCTGCGATG TGAGGAAAGGCACCTCCACCAGAAAACCTCGGATCAATTCTCAGCTGGTG GCACAACAGGTAGCACAGCAGTATGCCACTCCACCTCCCCCTAAGAAGGA GAAGAAGGAGAAGGTGGAAAAGCAAGACAAAGAGAAACCTGAGAAAGATA AGGAAATCAGTCCTAGTGTTACCAAGAAAAATACCAACAAAAAAACAAAA CCAAAGTCCGATATTCTGAAAGACCCTCCTAGCGAAGCAAACAGTATACA GTCTGCAAATGCTACAACAAAGACCAGCGACACGAATCACACCTCAAGGC CCCGGCTGAAAAACGTGGACAGGAGCACTGCACAGCAGTTGGCAGTAACT GTGGGCAACGTCACCGTCATTATCACAGACTTTAAAGAAAAGACTCGCTC CTCCTCGACGTCATCATCCACAGTGACCTCCAGTGCAGGGTCAGAACAGC AGAACCAGAGCAGCTCGGGGTCAGAGAGCACAGACAAGGGCTCCTCCCGT TCGTCCACGCCAAAAGGCGACATGTCAGCAGTAAATGATGAATCTTTC |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 316 | 1 | 316 | Insert and frame-shift 61-62:L-D^C, Insert and frame-shift 78-79:S-P^C |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
LeuProAlaProAlaAlaAlaLeuProGlyAlaProProProProProGlyValArgGly
||||||||||||||||||||||||||||||
LeuProAlaProAlaAlaAlaLeuProGlyGlyAlaAlaAlaAlaAlaValAlaValAla
CTTCCTGCGCCCGCCGCGGCCCTTCCCGGGGGCGCCGCCGCCGCCGCCGTCGCCGTCGCC
TyrProAlaArgAlaArgGly<->LeuGlnGlyAlaSerGlyGlyAlaArgPheProSer
|||||| ||| |||||| ||||||||| ||||||
TrpCysAlaArgGlnSerGlyProAlaProGlyAlaGlyGlyGlyAlaGlnPheProAla
TGGTGTGCGAGGCAGTCCGGCCCGGCCCCGGGTGCCGGTGGGGGAGCCCAGTTTCCTGCC
SerLeuSerLeuProValProGlyLysGlyGlyTrpValValSerArgAlaLysPhePro
|||||| ||| ||| ||||||||| |||||||||||||||
ProPheProLeuProAlaProGluGluGlyArgTrpValValAlaArgAlaLysPhePro
CCGTTCCCTCTTCCAGCCCCCGAAGAGGGTAGGTGGGTGGTCGCCCGAGCGAAGTTTCCA
AlaLeu-AspSerCysGluIleThrThrAlaHisProArgLeuCysPheAlaValSer-P
||| #||| |||||||||||||||||| |||||||||||||||||||||#|
Ala---#AspPheGlyGluIleThrThrAlaHisGlnArgLeuCysPheAlaValSer#P
GCA---CGATTTCGGCGAAATTACGACGGCTCACCAGCGCCTGTGTTTTGCTGTCTCTCC
roProPheSerCysSerLeuProLeuProSerLeuPheProHisSerProLeuLeuGlyA
|||||||||||||||||||| |||||| ||| ||||||||||||||| |
roProPheSerCysSerLeuSerValProSerProPheSerHisSerProLeuLeuArgA
CCCCTTTTTCCTGTTCCCTGTCTGTTCCCTCCCCTTTCTCCCACTCCCCACTCCTCCGAA
rgProLysArgGlnAlaLysProAlaAlaAspGluGlyPheTrpAspCysSerValCysT
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
rgProLysArgGlnAlaLysProAlaAlaAspGluGlyPheTrpAspCysSerValCysT
GGCCAAAAAGACAAGCGAAACCTGCGGCAGACGAAGGCTTTTGGGATTGTAGCGTCTGCA
hrPheArgAsnSerAlaGluAlaPheLysCysSerIleCysAspValArgLysGlyThrS
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hrPheArgAsnSerAlaGluAlaPheLysCysSerIleCysAspValArgLysGlyThrS
CCTTCAGGAACAGCGCCGAAGCCTTTAAATGCAGCATCTGCGATGTGAGGAAAGGCACCT
erThr{Ar} >>>> Target Intron 1 >>>> {g}LysProArgIleAsnSerG
|||||{||} 78938 bp {|}|||||||||||||||||||
erThr{Ar}++ ++{g}LysProArgIleAsnSerG
CCACC{AG}gt ag{A}AAACCTCGGATCAATTCTC
lnLeuValAlaGlnGlnValAlaGlnGlnTyrAlaThrProProProProLysLysGluL
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
lnLeuValAlaGlnGlnValAlaGlnGlnTyrAlaThrProProProProLysLysGluL
AGCTGGTGGCACAACAGGTAGCACAGCAGTATGCCACTCCACCTCCCCCTAAGAAGGAGA
ysLysGluLysValGluLysGlnAspLysGluLysProGluLysAspLysGluIleSerP
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ysLysGluLysValGluLysGlnAspLysGluLysProGluLysAspLysGluIleSerP
AGAAGGAGAAGGTGGAAAAGCAAGACAAAGAGAAACCTGAGAAAGATAAGGAAATCAGTC
roSerValThrLysLysAsnThrAsnLysLysThr{Ly} >>>> Target Intron
|||||||||||||||||||||||||||||||||||{||} 93 bp
roSerValThrLysLysAsnThrAsnLysLysThr{Ly}++
CTAGTGTTACCAAGAAAAATACCAACAAAAAAACA{AA}gt
2 >>>> {s}ProLysSerAspIleLeuLysAspProProSerGluAlaAsnSerIleG
{|}|||||||||||||||||||||||||||||||||||||||||||||||||
++{s}ProLysSerAspIleLeuLysAspProProSerGluAlaAsnSerIleG
ag{A}CCAAAGTCCGATATTCTGAAAGACCCTCCTAGCGAAGCAAACAGTATAC
lnSerAlaAsnAlaThrThrLysThrSerGluThrAsnHisThrSer{Ar} >>>> Ta
||||||||||||||||||||||||||||| |||||||||||||||{||}
lnSerAlaAsnAlaThrThrLysThrSerAspThrAsnHisThrSer{Ar}++
AGTCTGCAAATGCTACAACAAAGACCAGCGACACGAATCACACCTCA{AG}gt
rget Intron 3 >>>> {g}ProArgLeuLysAsnValAspArgSerThrAlaGlnG
409 bp {|}|||||||||||||||||||||||||||||||||||||
++{g}ProArgLeuLysAsnValAspArgSerThrAlaGlnG
ag{G}CCCCGGCTGAAAAACGTGGACAGGAGCACTGCACAGC
lnLeuAlaValThrValGlyAsnValThrValIleIleThrAspPheLysGluLysThrA
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
lnLeuAlaValThrValGlyAsnValThrValIleIleThrAspPheLysGluLysThrA
AGTTGGCAGTAACTGTGGGCAACGTCACCGTCATTATCACAGACTTTAAAGAAAAGACTC
rgSerSerSerThrSerSerSerThrValThrSerSerAlaGlySerGluGlnGlnAsnG
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
rgSerSerSerThrSerSerSerThrValThrSerSerAlaGlySerGluGlnGlnAsnG
GCTCCTCCTCGACGTCATCATCCACAGTGACCTCCAGTGCAGGGTCAGAACAGCAGAACC
lnSerSerSerGlySerGluSerThrAspLysGlySerSerArgSerSerThrProLysG
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
lnSerSerSerGlySerGluSerThrAspLysGlySerSerArgSerSerThrProLysG
AGAGCAGCTCGGGGTCAGAGAGCACAGACAAGGGCTCCTCCCGTTCGTCCACGCCAAAAG
lyAspMetSerAlaValAsnAspGluSerPhe
||||||||||||||||||||||||||||||||
lyAspMetSerAlaValAsnAspGluSerPhe
GCGACATGTCAGCAGTAAATGATGAATCTTTC
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