| Basic information |
| Official Symbol | PVRIG |
| Description | poliovirus receptor related immunoglobulin domain containing |
| Other Aliases | C7orf15 |
| Other Description | poliovirus receptor-related immunoglobulin domain-containing protein; transmembrane protein PVRIG |
| Mutation type | Insert and frame-shift 23-24:H-R^GCCT, premature termination 200:P->TGA |
| Location | Scaffold000465_1:2806489 2805736 - |
| Wiki | Wikipedia GeneCard |
| Sequence |
| PVRIG |
ATGAGAACAGAAACACAGGTGCCGTCCGTGCAGCCCCCGGAGCCTGGGCT GGAGGGGTACCATGGGCAGCGACCCCTGGCCCTGCCCTGGGCGCTGCTGA CCCTCTGCATCACTGCTGGGACGCCTGAAGTGTGGGTGCAAGTTCAGATG GAGGACACTGAGCTCCCAACTTTCACTATCCACTGTGGGTTCCTAGGGTC TGGTTCTATCTCATTGGTGACTGTGAGCTGGGGGGGGCCTGACGGTGCTG GAGGGACCAGGCTGGCTGTGTTGCACCCAGAATTTGGCACCCAACAGTGG GCTCCTGCCCGCTGGGCCCGCTGGGAAACCGGAAGCAGCATTTCTCTCAG CCTGGAAGGGTCCAAGGCAAGAAGCCCCAGCTCCAATACCACCTTCTGCT GCAAGTTTGCTTCCTTCCCTGAGGGCTCCCAGGAAGCCTGCAGGAGCCAC CTGCCTGGCTCAGACCAAGGGTTTCCTGCCCCAACTCCAGCCCCCATTTT GCCGGCAGACCTGGCCGGGATTTTGGGGGTCTCAGGGGTCCTGCTCTTTG GCTGCATCTACCTCCTACACCTCCTGCGCCGGCAGAGACATTGGTGAGCC CCA |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 326 | 1 | 202 | Insert and frame-shift 23-24:H-R^GCCT, Premature termination 200:P->TGA |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
MetArgThrGluAlaGlnValProAlaLeuGlnProProGluProGlyLeuGluGlyAlaMe
|||||||||||| ||||||||| |||||||||||||||||||||||||||
MetArgThrGluThrGlnValProSerValGlnProProGluProGlyLeuGluGlyTyrHi
ATGAGAACAGAAACACAGGTGCCGTCCGTGCAGCCCCCGGAGCCTGGGCTGGAGGGGTACCA
tGlyHis----ArgThrLeuValLeuProTrpValLeuLeuThrLeuCysValThrAla{G}
||| ####||| ||| ||||||||| ||||||||||||||| ||||||{|}
sGlyGln####ArgProLeuAlaLeuProTrpAlaLeuLeuThrLeuCysIleThrAla{G}
TGGGCAGGCCTCGACCCCTGGCCCTGCCCTGGGCGCTGCTGACCCTCTGCATCACTGCT{G}
>>>> Target Intron 1 >>>> {ly}ThrProGluValTrpValGlnValArgMe
77 bp {||}|||||||||||||||||||||||| ||
++ ++{ly}ThrProGluValTrpValGlnValGlnMe
gt ag{GG}ACGCCTGAAGTGTGGGTGCAAGTTCAGAT
tGluAlaThrGluLeuSerSerPheThrIleArgCysGlyPheLeuGlySerGlySerIleS
|||| ||||||||| ||||||||| ||||||||||||||||||||||||||||
tGluAspThrGluLeuProThrPheThrIleHisCysGlyPheLeuGlySerGlySerIleS
GGAGGACACTGAGCTCCCAACTTTCACTATCCACTGTGGGTTCCTAGGGTCTGGTTCTATCT
erLeuValThrValSerTrpGlyGlyProAsnGlyAlaGlyGlyThrThrLeuAlaValLeu
||||||||||||||||||||||||||||| ||||||||||||||| ||||||||||||
erLeuValThrValSerTrpGlyGlyProAspGlyAlaGlyGlyThrArgLeuAlaValLeu
CATTGGTGACTGTGAGCTGGGGGGGGCCTGACGGTGCTGGAGGGACCAGGCTGGCTGTGTTG
HisProGluArgGlyIleArgGlnTrpAlaProAlaArgGlnAlaArgTrpGluThrGlnSe
||||||||| ||| |||||||||||||||||| ||||||||||||||| ||
HisProGluPheGlyThrGlnGlnTrpAlaProAlaArgTrpAlaArgTrpGluThrGlySe
CACCCAGAATTTGGCACCCAACAGTGGGCTCCTGCCCGCTGGGCCCGCTGGGAAACCGGAAG
rSerIleSerLeuIleLeuGluGlySerGlyAlaSerSerProCysAlaAsnThrThrPheC
||||||||||||| |||||||||||| ||| |||||| |||||||||||||
rSerIleSerLeuSerLeuGluGlySerLysAlaArgSerProSerSerAsnThrThrPheC
CAGCATTTCTCTCAGCCTGGAAGGGTCCAAGGCAAGAAGCCCCAGCTCCAATACCACCTTCT
ysCysLysPheAlaSerPheProGluGlySerTrpGluAlaCysGlySerLeuProProSer
|||||||||||||||||||||||||||||||| ||||||||| ||| |||
ysCysLysPheAlaSerPheProGluGlySerGlnGluAlaCysArgSerHisLeuProGly
GCTGCAAGTTTGCTTCCTTCCCTGAGGGCTCCCAGGAAGCCTGCAGGAGCCACCTGCCTGGC
SerAspPro{G} >>>> Target Intron 2 >>>> {ly}LeuSerAlaProProTh
|||||| {|} 70 bp {||} ||| |||||
SerAspGln{G}++ ++{ly}PheProAla---ProTh
TCAGACCAA{G}gt ag{GG}TTTCCTGCC---CCAAC
rProAlaProIleLeuArgAlaAspLeuAlaGlyIleLeuGlyValSerGlyValLeuLeuP
|||||||||||||||| |||||||||||||||||||||||||||||||||||||||||||
rProAlaProIleLeuProAlaAspLeuAlaGlyIleLeuGlyValSerGlyValLeuLeuP
TCCAGCCCCCATTTTGCCGGCAGACCTGGCCGGGATTTTGGGGGTCTCAGGGGTCCTGCTCT
heGlyCysValTyrLeuLeuHisLeuLeuArgArgHisLysHisArgProAlaPro
|||||||| |||||||||||||||||||||||| ||| ||||||
heGlyCysIleTyrLeuLeuHisLeuLeuArgArgGlnArgHisTrp***AlaPro
TTGGCTGCATCTACCTCCTACACCTCCTGCGCCGGCAGAGACATTGGTGAGCCCCA
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