| Basic information |
| Official Symbol | PSMC1 |
| Description | proteasome (prosome, macropain) 26S subunit, ATPase, 1 |
| Other Aliases | P26S4, S4, p56 |
| Other Description | 26S protease regulatory subunit 4; 26S proteasome AAA-ATPase subunit RPT2; proteasome 26S ATPase subunit 1; proteasome 26S subunit ATPase 1; proteasome 26S subunit, ATPase, 1 |
| Mutation type | Insert and frame-shift 263-264:G-P^TGGG, Insert and frame-shift 409-410:E-R^TA, Insert and frame-shift 41-42:K-G^GAAG, Insert and frame-shift 419-420:F-K^A, Insert and frame-shift 72-73:L-L^C, premature termination 62:L->TGA |
| Location | Scaffold139943_1:2462608 2463915 + |
| Wiki | Wikipedia GeneCard |
| Sequence |
| PSMC1 |
ATGGGTCAAAGTCAGAGTGGCGGTCATAGTACTGGAGGTGGAAAGAAGGA TGACAAGGACAAGAAAAAGAAGTATGAATCTCCTGTCCCAACTAGAGTGG GGAAACAAAAGAAGGAAACAAAAGGACCAGATGCTACCAGCAAACTGCCA CTGGTGACACCTCACACACAGTGCCAGTTAAAATGATTGAAATTAGAGAG AATTAAAGACTACCTTGCATTGGAAGAAGAATTCATTAGAAATCAGGAAC AGATGAAACCATTAGAAGAAAAGCAAGAGGAGGAAAGATCAAAGGTGGAT AATCTGAGGGGGACCCCAATGTTAGTAGGAACCTTGGAAGAGATCATTGA TGACAATCATGCCATCGTGTCTACATCTGTGGGTTCAGAACACCATGTCA GCATTTTTTCACTTGTAGACAAGGATCTGTTGGAACCAGACTGCTCAGTC CCATTCAACTACAAGGTGCATGCAGTGATAGGGATGCTGATGGATGACAC GGATCCCTTGGTCACAGTGACGAAGGTGGAAAGGGCTCTGCAGGATACCT ATGCCAGTATTGGGGGTTTGGAAAACCAGATCCAGGAGATTAAGGAATCT GTGGAGCTTCCTCTCACCCATCCTGAATGTTATGAAGAGATGGGTATAAA GCCCCCCAAGGGGGTCATTCTTTATGGTCCCCCTCACACAGGAAAAACCT TGTTAGCCAAAGCAGTTGCAAACCAAACTTCAGCCACTTTCTTGAGAGTT GTTGGCTCTGAACTGATTCAGAAGTACCTGGGTGATGGACCCAAACTTGT ACGGGAACTCTTTCAAGTTGCTGAAGAGCATGCACCATCCATTGTGTTTA CTGATGAAATTGATGTGATTGGGACAAAAAGATATGACTCAAATTCTGGT GGTGAAAGAGAAATTCAGCAAACAATGTTGGAACTGTTGAACCAGCTGGA TGGATTTGATTCAAGGGGAGATGTGAAAGTTGTTATGGCCACACACCTAA TAGAGACTTTGGATCCAGTGCTTATTAGACCAGGCTGCATTGACAGGAAG ATTGAGTTCCCCTTGCCTGATGAAAAGACCAAGGAGCGCATATTTCAGAT TCACACAAGCAGGATGACGCTGGCCGATGATGTAACCCTGGATGACCTGA TGATGGCTAAGGATGACCTGTCTGGTGCCGACGTCAAAGCAGTTTGTACA GAAGCTGGTCTGATGGCCTTGAGAGTACGGAGAATGAAAGTAACAAATGA AGCCTTCAAAAAATCTAAAGGAAATGTTTTCTTTATGAAACAAGAA |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 440 | 1 | 432 | Insert and frame-shift 263-264:G-P^TGGG, Insert and frame-shift 409-410:E-R^TA, Insert and frame-shift 41-42:K-G^GAAG, Insert and frame-shift 419-420:F-K^A, Insert and frame-shift 72-73:L-L^C, Premature termination 62:L->TGA |
Instructions: *** -> premature termination codon; # -> frame shift Alignment: Human pep sequence ---> |||||||||||||||||||||| Treeshrew pep sequence ---> Treeshrew cds sequence ---> MetGlyGlnSerGlnSerGlyGlyHisGlyProGlyGlyGlyLysLysAspAspLysAspLy ||||||||||||||||||||||||||| ||||||||||||||||||||||||||||| MetGlyGlnSerGlnSerGlyGlyHisSerThrGlyGlyGlyLysLysAspAspLysAspLy ATGGGTCAAAGTCAGAGTGGCGGTCATAGTACTGGAGGTGGAAAGAAGGATGACAAGGACAA sLysLysLysTyrGluProProValProThrArgValGlyLysLysLysLysLysThrLys- |||||||||||||||| |||||||||||||||||||||||| |||||| ||||||# sLysLysLysTyrGluSerProValProThrArgValGlyLysGlnLysLysGluThrLys# GAAAAAGAAGTATGAATCTCCTGTCCCAACTAGAGTGGGGAAACAAAAGAAGGAAACAAAAG ---GlyProAspAlaAlaSerLysLeuProLeuValThrProHisThrGlnCysArgLeuLy ###|||||||||||| |||||||||||||||||||||||||||||||||||| ||||| ###GlyProAspAlaThrSerLysLeuProLeuValThrProHisThrGlnCysGlnLeuLy AAGGGACCAGATGCTACCAGCAAACTGCCACTGGTGACACCTCACACACAGTGCCAGTTAAA sLeuLeuLysLeuGluArgIleLysAspTyrLeu-LeuMetGluGluGluPheIleArgAsn | ||||||||||||||||||||||||||||||# ||||||||||||||||||||| s***LeuLysLeuGluArgIleLysAspTyrLeu#AlaLeuGluGluGluPheIleArgAsn ATGATTGAAATTAGAGAGAATTAAAGACTACCTTCGCATTGGAAGAAGAATTCATTAGAAAT GlnGluGlnMetLysProLeuGluGluLysGlnGluGluGluArgSerLysValAspAspLe ||||||||||||||||||||||||||||||||||||||||||||||||||||||||| || GlnGluGlnMetLysProLeuGluGluLysGlnGluGluGluArgSerLysValAspAsnLe CAGGAACAGATGAAACCATTAGAAGAAAAGCAAGAGGAGGAAAGATCAAAGGTGGATAATCT uArgGlyThrProMetSerValGlyThrLeuGluGluIleIleAspAspAsnHisAlaIleV |||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||| uArgGlyThrProMetLeuValGlyThrLeuGluGluIleIleAspAspAsnHisAlaIleV GAGGGGGACCCCAATGTTAGTAGGAACCTTGGAAGAGATCATTGATGACAATCATGCCATCG alSerThrSerValGlySerGluHisTyrValSerIleLeuSerPheValAspLysAspLeu |||||||||||||||||||||||||| ||||||||| ||| ||||||||||||||| alSerThrSerValGlySerGluHisHisValSerIlePheSerLeuValAspLysAspLeu TGTCTACATCTGTGGGTTCAGAACACCATGTCAGCATTTTTTCACTTGTAGACAAGGATCTG LeuGluProGlyCysSerValLeuLeuAsnHisLysValHisAlaValIleGlyValLeuMe ||||||||| ||||||||| ||| ||||||||||||||||||||| ||||| LeuGluProAspCysSerValProPheAsnTyrLysValHisAlaValIleGlyMetLeuMe TTGGAACCAGACTGCTCAGTCCCATTCAACTACAAGGTGCATGCAGTGATAGGGATGCTGAT tAspAspThrAspProLeuValThrValMetLysValGluLysAlaProGlnGluThrTyrA |||||||||||||||||||||||||||| ||||||||| ||| ||| ||||||| tAspAspThrAspProLeuValThrValThrLysValGluArgAlaLeuGlnAspThrTyrA GGATGACACGGATCCCTTGGTCACAGTGACGAAGGTGGAAAGGGCTCTGCAGGATACCTATG laAspIleGlyGlyLeuAspAsnGlnIleGlnGluIleLysGluSerValGluLeuProLeu || |||||||||||| |||||||||||||||||||||||||||||||||||||||||| laSerIleGlyGlyLeuGluAsnGlnIleGlnGluIleLysGluSerValGluLeuProLeu CCAGTATTGGGGGTTTGGAAAACCAGATCCAGGAGATTAAGGAATCTGTGGAGCTTCCTCTC ThrHisProGluTyrTyrGluGluMetGlyIleLysProProLysGlyValIleLeuTyrGl |||||||||||| ||||||||||||||||||||||||||||||||||||||||||||||| ThrHisProGluCysTyrGluGluMetGlyIleLysProProLysGlyValIleLeuTyrGl ACCCATCCTGAATGTTATGAAGAGATGGGTATAAAGCCCCCCAAGGGGGTCATTCTTTATGG yProProGlyThrGlyLysThrLeuLeuAlaLysAlaValAlaAsnGlnThrSerAlaThrP ||||||| |||||||||||||||||||||||||||||||||||||||||||||||||||| yProProHisThrGlyLysThrLeuLeuAlaLysAlaValAlaAsnGlnThrSerAlaThrP TCCCCCTCACACAGGAAAAACCTTGTTAGCCAAAGCAGTTGCAAACCAAACTTCAGCCACTT heLeuArgValValGlySerGluLeuIleGlnLysTyrLeuGlyAspGly----ProLysLe ||||||||||||||||||||||||||||||||||||||||||||||||||####|||||||| heLeuArgValValGlySerGluLeuIleGlnLysTyrLeuGlyAspGly####ProLysLe TCTTGAGAGTTGTTGGCTCTGAACTGATTCAGAAGTACCTGGGTGATGGATGGGCCCAAACT uValArgGluLeuPheArgValAlaGluGluHisAlaProSerIleValPheIleAspGluI |||||||||||||||| ||||||||||||||||||||||||||||||||| ||||||| uValArgGluLeuPheGlnValAlaGluGluHisAlaProSerIleValPheThrAspGluI TGTACGGGAACTCTTTCAAGTTGCTGAAGAGCATGCACCATCCATTGTGTTTACTGATGAAA leAspAlaIleGlyThrLysArgTyrAspSerAsnSerGlyGlyGluArgGluIleGlnArg ||||| ||||||||||||||||||||||||||||||||||||||||||||||||||| leAspValIleGlyThrLysArgTyrAspSerAsnSerGlyGlyGluArgGluIleGlnGln TTGATGTGATTGGGACAAAAAGATATGACTCAAATTCTGGTGGTGAAAGAGAAATTCAGCAA ThrMetLeuGluLeuLeuAsnGlnLeuAspGlyPheAspSerArgGlyAspValLysValIl |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| ThrMetLeuGluLeuLeuAsnGlnLeuAspGlyPheAspSerArgGlyAspValLysValVa ACAATGTTGGAACTGTTGAACCAGCTGGATGGATTTGATTCAAGGGGAGATGTGAAAGTTGT eMetAlaThrAsnArgIleGluThrLeuAspProAlaLeuIleArgProGlyArgIleAspA ||||||||| |||||||||||||||||| ||||||||||||||| ||||||| lMetAlaThrHisLeuIleGluThrLeuAspProValLeuIleArgProGlyCysIleAspA TATGGCCACACACCTAATAGAGACTTTGGATCCAGTGCTTATTAGACCAGGCTGCATTGACA rgLysIleGluPheProLeuProAspGluLysThrLysLysArgIlePheGlnIleHisThr |||||||||||||||||||||||||||||||||||||| ||||||||||||||||||||| rgLysIleGluPheProLeuProAspGluLysThrLysGluArgIlePheGlnIleHisThr GGAAGATTGAGTTCCCCTTGCCTGATGAAAAGACCAAGGAGCGCATATTTCAGATTCACACA SerArgMetThrLeuAlaAspAspValThrLeuAspAspLeuIleMetAlaLysAspAspLe |||||||||||||||||||||||||||||||||||||||||| ||||||||||||||||| SerArgMetThrLeuAlaAspAspValThrLeuAspAspLeuMetMetAlaLysAspAspLe AGCAGGATGACGCTGGCCGATGATGTAACCCTGGATGACCTGATGATGGCTAAGGATGACCT uSerGlyAlaAspIleLysAlaIleCysThrGluAlaGlyLeuMetAlaLeuArgGlu--Ar ||||||||||||| |||||| |||||||||||||||||||||||||||||| ##|| uSerGlyAlaAspValLysAlaValCysThrGluAlaGlyLeuMetAlaLeuArgVal##Ar GTCTGGTGCCGACGTCAAAGCAGTTTGTACAGAAGCTGGTCTGATGGCCTTGAGAGTATACG gArgMetLysValThrAsnGluAspPhe-LysLysSerLysGluAsnValLeuTyrLysLys |||||||||||||||||||||| |||#|||||||||||| |||||| ||| gArgMetLysValThrAsnGluAlaPhe#LysLysSerLysGlyAsnValPhePheMetLys GAGAATGAAAGTAACAAATGAAGCCTTCAAAAAAATCTAAAGGAAATGTTTTCTTTATGAAA GlnGlu |||||| GlnGlu CAAGAA // |