| Basic information |
| Official Symbol | PPM1N |
| Description | protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative) |
| Other Aliases | NA |
| Other Description | probable protein phosphatase 1N |
| Mutation type | Insert and frame-shift 180-181:C-G^A, Insert and frame-shift 295-296:L-G^TG, Insert and frame-shift 326-327:F-P^C |
| Location | Scaffold000067_1:3375225 3377253 + |
| Wiki | Wikipedia GeneCard |
| Sequence |
| PPM1N |
AAGGAAGAGGAGGCCGAAGGACTCAGGGCCCCCAGCAAAAGTCGGTCTCT TCTGGACGTGAGGCGATGCGCTCAGCGGCCGCATGGGGGTGCGGCAGCGT CGTGGAGGCTGAGCTTCGGGGCGAGCGCCGTGCAGGGCTGGCGCGCACTA GTTGAGGATGCGCACTGCGCTTGGCTCGCGTTGCCTAGTCTGCCTCCAGG CTGGGCTTTCTTCGCCGTCCTCGACGGCCGCGGCGGGGCGCGAGCTGCCC GCTTTGTCGCGCGCCACCTGCCAGACCACGTGCCGGAGACTCTGGACCTG GCGCCGGACAAGCCCGAGGGCGTGCGTCAGGCTCTGCGCCGAGCCTTCTT GAGCGCCGACGAACGCCTGCGCGCTCTCTGGCTGTGGCGTTGCTTATCTC CCCGAGCTCTGTGTCCTGGCTCACTCCTGAGCCGCGCTGGCGCTGTCGCC TTCAGCACCGAGCACCGGCCCCTTCGGTCCCGGGAACGCGAGCGCATCCA CGATGCGGGCGGCATGATCTACCGCCGGCTCGTCGAGGACGCTCTAGCCG TGTCGCGAGCATTGGGCGACTTTGTCTACAAGGACGCCCTGGGGAGGCCC CCCGAGTTGTGGCTCCGTGCTGCGGAGCCTGAGGTGGCCGCACTGGCACG CTGGGATGAGGACGAATTCATGCTCCTAGCTTCTGACGGCGTGTGGGACT CGATGTCTGGTGCTGCTCTGGTGGAAGTGGTGGCGTCACGCCTCCGTGGC CTACCCCCAGAGCTTCTCTGTGCGCAGCTGTTGGACACGTGTCCACTCCA GGGCAGCCTGGACAACATGACCTGCATCCTGGTCTGCTCCCCGGGAGCAC CTAGGCCTTGCGAGGAGGCAGTCAGGAGGGAGCTAGAGCTGGACGCAGGC CTGGGCAGCAGAGTCCAGAAGCTGTGCACCTCTGCTCAGGAGCCCCTCTC CCTCTCCAGCCTAAATGCAGTTTTCAGGACTCTGGCCTCGAATGATAAAG GTGCCCCTCCTGAGGGCCTTCCTCTACTCCCCAGGGCCACTGTCATCTCT GAAGCCTATTCTCAGCTCTGCCAGGCCTCAGAAGAGTGCTGGGAA |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 430 | 29 | 408 | Insert and frame-shift 180-181:C-G^A, Insert and frame-shift 295-296:L-G^TG, Insert and frame-shift 326-327:F-P^C |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
GluGluGluGluGluAlaGlyArgArgAlaProGluGlyProArgSerLeuLeuThrAlaPr
||||||||| ||| ||||||||| ||||||||||||
LysGluGluGluAlaGluGlyLeuArgAlaProSerLysSerArgSerLeuLeuAspValAr
AAGGAAGAGGAGGCCGAAGGACTCAGGGCCCCCAGCAAAAGTCGGTCTCTTCTGGACGTGAG
oArgArgAlaGlnArgProHisGlyGlyAlaGluAlaSerGlyGlyLeuArgPheGlyAlaS
||| |||||||||||||||||||||||| |||||| ||| ||||||||||
gArgCysAlaGlnArgProHisGlyGlyAlaAlaAlaSerTrpArgLeuSerPheGlyAlaS
GCGATGCGCTCAGCGGCCGCATGGGGGTGCGGCAGCGTCGTGGAGGCTGAGCTTCGGGGCGA
erAlaAlaGlnGlyTrpArgAlaArgMetGluAspAlaHisCysThrTrpLeuSerLeuPro
||||| ||||||||||||||| ||||||||||||||| |||||| ||||||
erAlaValGlnGlyTrpArgAlaLeuValGluAspAlaHisCysAlaTrpLeuAlaLeuPro
GCGCCGTGCAGGGCTGGCGCGCACTAGTTGAGGATGCGCACTGCGCTTGGCTCGCGTTGCCT
GlyLeuProProGlyTrpAlaLeuPheAlaValLeuAspGlyHisGlyGlyAlaArgAlaAl
|||||||||||||||||| |||||||||||||||||| |||||||||||||||||
SerLeuProProGlyTrpAlaPhePheAlaValLeuAspGlyArgGlyGlyAlaArgAlaAl
AGTCTGCCTCCAGGCTGGGCTTTCTTCGCCGTCCTCGACGGCCGCGGCGGGGCGCGAGCTGC
aArgPheGlyAlaArgHisLeuProGlyHisValLeuGlnGluLeuGlyProGluProSerG
||||||| ||||||||||||||| |||||| ||| |||
aArgPheValAlaArgHisLeuProAspHisValProGluThrLeuAspLeuAlaProAspL
CCGCTTTGTCGCGCGCCACCTGCCAGACCACGTGCCGGAGACTCTGGACCTGGCGCCGGACA
luProGluGlyValArgGluAlaLeuArgArgAlaPheLeuSerAlaAspGluArgLeuArg
||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
ysProGluGlyValArgGlnAlaLeuArgArgAlaPheLeuSerAlaAspGluArgLeuArg
AGCCCGAGGGCGTGCGTCAGGCTCTGCGCCGAGCCTTCTTGAGCGCCGACGAACGCCTGCGC
SerLeuTrpProArgValGluThrGlyGlyCysThrAlaValValLeuLeuValSerProAr
|||||| ||||||||
AlaLeuTrp------------------------------LeuTrpArgCysLeuSerProAr
GCTCTCTGG------------------------------CTGTGGCGTTGCTTATCTCCCCG
gPheLeuTyrLeuAlaHisCys-GlyAspSerArgAlaValLeuSerArgAlaGlyAlaVal
| ||| |||# ||| |||||||||||||||||||||
gAlaLeu------------Cys#ProGlySer------LeuLeuSerArgAlaGlyAlaVal
AGCTCTG------------TGTACCTGGCTCA------CTCCTGAGCCGCGCTGGCGCTGTC
AlaPheSerThrGluAspHisArgProLeuArgProArgGluArgGluArgIleHisAlaAl
||||||||||||||| ||||||||||||||| ||||||||||||||||||||| ||
AlaPheSerThrGlu---HisArgProLeuArgSerArgGluArgGluArgIleHisAspAl
GCCTTCAGCACCGAG---CACCGGCCCCTTCGGTCCCGGGAACGCGAGCGCATCCACGATGC
aGlyGlyThrIleArgArgArgArgValGluGlySerLeuAlaValSerArgAlaLeuGlyA
||||||| ||| |||||| |||||| |||||||||||||||||||||||||
aGlyGlyMetIleTyrArgArgLeuValGluAspAlaLeuAlaValSerArgAlaLeuGlyA
GGGCGGCATGATCTACCGCCGGCTCGTCGAGGACGCTCTAGCCGTGTCGCGAGCATTGGGCG
spPheThrTyrLysGluAlaProGlyArgProProGluLeuGlnLeuValSerAlaGluPro
||||| |||||| ||| |||||||||||||||||| ||| |||||||||
spPheValTyrLysAspAlaLeuGlyArgProProGluLeuTrpLeuArgAlaAlaGluPro
ACTTTGTCTACAAGGACGCCCTGGGGAGGCCCCCCGAGTTGTGGCTCCGTGCTGCGGAGCCT
GluValAlaAlaLeuAlaArgGlnAlaGluAspGluPheMetLeuLeuAlaSerAspGlyVa
||||||||||||||||||||| |||||||||||||||||||||||||||||||||||
GluValAlaAlaLeuAlaArgTrpAspGluAspGluPheMetLeuLeuAlaSerAspGlyVa
GAGGTGGCCGCACTGGCACGCTGGGATGAGGACGAATTCATGCTCCTAGCTTCTGACGGCGT
lTrpAspThrValSerGlyAlaAlaLeuAlaGlyLeuValAlaSerArgLeuArgLeu--Gl
||||||| ||||||||||||||| |||||||||||||||||| ##||
lTrpAspSerMetSerGlyAlaAlaLeuValGluValValAlaSerArgLeuArg---##Gl
GTGGGACTCGATGTCTGGTGCTGCTCTGGTGGAAGTGGTGGCGTCACGCCTCCGT---TGGG
yLeuAlaProGluLeuLeuCysAlaGlnLeuLeuAspThrCysLeu >>>> Target In
|||| |||||||||||||||||||||||||||||||||||| 824
yLeuProProGluLeuLeuCysAlaGlnLeuLeuAspThrCysPro++
CCTACCCCCAGAGCTTCTCTGTGCGCAGCTGTTGGACACGTGTCCAgt
tron 1 >>>> CysLysGlySerLeuAspAsnMetThrCysIleLeuValCysPhe-Pro
bp |||||||||||||||||||||||||||||||||||| #|||
--LeuGlnGlySerLeuAspAsnMetThrCysIleLeuValCysSer#Pro
ctCTCCAGGGCAGCCTGGACAACATGACCTGCATCCTGGTCTGCTCCCCCG
GlyAlaProArgProSerGluGluAlaIleArgArgGluLeuAlaLeuAspAlaAlaLeuGl
||||||||||||||| ||||||||| |||||||||||| ||||||||| |||||
GlyAlaProArgProCysGluGluAlaValArgArgGluLeuGluLeuAspAlaGlyLeuGl
GGAGCACCTAGGCCTTGCGAGGAGGCAGTCAGGAGGGAGCTAGAGCTGGACGCAGGCCTGGG
yCysArgIleAla{G} >>>> Target Intron 2 >>>> {lu}LeuCysAlaSerA
| ||| { } 51 bp { }|||||| ||||
ySerArgValGln{L}+- ++{ys}LeuCysThrSerA
CAGCAGAGTCCAG{A}gg ag{AG}CTGTGCACCTCTG
laGlnLysPro<-><-><->ProSerLeuAsnThrValPheArgThrLeuAla{Se} >>>
||||| ||| ||||||||| ||||||||||||||||||{||}
laGlnGluProLeuSerLeuSerSerLeuAsnAlaValPheArgThrLeuAla{Se}-+
CTCAGGAGCCCCTCTCCCTCTCCAGCCTAAATGCAGTTTTCAGGACTCTGGCC{TC}ct
> Target Intron 3 >>>> {r}GluAspIleProAspLeuProProGlyGlyGlyLe
55 bp {|} ||| ||| ||| ||
-+{r}AsnAspLysGlyAlaProProGluGlyLeuProLe
gg{G}AATGATAAAGGTGCCCCTCCTGAGGGCCTTCCTCT
uAspCysLysAlaThrValIleAlaGluValTyrSerGlnIleCysGlnValSerGluGluC
| |||||||||||| ||| ||||||||| |||||| ||||||||||
uLeuProArgAlaThrValIleSerGluAlaTyrSerGlnLeuCysGlnAlaSerGluGluC
ACTCCCCAGGGCCACTGTCATCTCTGAAGCCTATTCTCAGCTCTGCCAGGCCTCAGAAGAGT
ysGlyGlu
|| |||
ysTrpGlu
GCTGGGAA
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