| Basic information |
| Official Symbol | PHF16 |
| Description | PHD finger protein 16 |
| Other Aliases | JADE3 |
| Other Description | protein Jade-3 |
| Mutation type | Insert and frame-shift 807-808:C-H^T |
| Location | Scaffold138400_2:329048 279345 - |
| Wiki | Wikipedia GeneCard |
| Sequence |
| PHF16 |
TCCCAGGTGTTCCGGAAGGACCTCATCAGTGCCATGAAACTTCCAGATTC TCACCACATTAATCCTGACAGTTATTACCTCTTTGCGGATACATGGAAGG AAGAATGGGAAAAGGGAGTCCAGGTACCAGTCAGTCCAGACACTGTTCCA GAGCCTTCTCTCAGGATTATAGCTGAAAAGGAAAAAGATGTTTTGTTTAT TCAACCTCGGAAATATATCCGCTGTTCTACACCAGAGGCCACAGAACCTG GCTCTATCAACATCTCGCATCTGGCAGCATCTGTATGCCGCTATGACCTG GATGACATGGACATCTTCTGGCTCCAGGAACTCAATGAAGACCTTACACA AATGGGTTGTGAGCCAGTTGATGAGACTCTTATGGAAAAGACAGTAGAAG TCCTGGAACGTCATTGCCATGAAAATATGAACCATGCTATTAAGACAGAG GAAGGGCTAGGCATAGAGTATGATGAAGATGTGATCTGTGATGTGTGCCG GTCTCCAGACAGTGAAGAAGGGAATGATATGGTATTCTGTGATAAGTGTA ACATCTGTGTGCATCAGGCCTGCTATGGCATCCTTAAGGTTCCAGAAGGC AGCTGGCTATGTCGTGCCTGTGTCATGGGCATTCATCCTCAGTGTCTGTT ATGTCCAAAGACTGGTGGAGCCATGAAGACCACCAGGACAGGGGATAAAT GGGCTCATGTCAGCTGTGCCCTGTGGATTCCAGAGGTCAACATTGCTTGT CCTGAGAGGATGGAACCAATTACAAAGATCTCTCACATCCCACCCAGTCG GTGGGCCTTAGTCTGCAACCTGTGCAAGATGAAAACAGGAGCTTGCATTC AGTGCTCAGTGAAAAGCTGTATAACTGCCTTCCATGTCACCTGTGCCTTT GAGCACAATCTCGAGATGAAGACCATTCTAGATGATGAGGATGAAGTGAA GTTCAAATCATACTGTCTTAAACATAGCCAAAACAGACAGAAGATTGGGG AAGCTGAGTACCCCCACCACTGGGCTGCAGAGCAAAGCCAAGCTAAAAGT GAGAAAACTAGCCTGCGGGCCCAGAAGCTTCGGGAGCTAGAAGAGGACTT CTACACCCTGGTCCGAGTAGAAGATGTGGCCAAAGAACTGGAGCTGCCCA TGCTAGTTGTGGATTTTATCTATAACTACTGGAAACTAAAGCGTAAAAGT AACTTCAATAAGCCATTATTCCCTCCAAAGGAGGACGAAGGAAATGGCCT GGTACAGCCAAAAGAGGAAAGTGTTCACACTCGTATGAGAATGTTTATGC ACCTTCGGCAAGACTTGGAAAGGGTCCGAAATCTGTGCTACATGATAAGC AGACGAGAGAAGATGAAATTGTCACAGAGCAGGCTACAGGAACAGATCTT CGGTTTGCAGGTTCAGCTTGTTAACCAAGAAATGGCTGCAGGACTTCCTT TGACCAATACACTAGAAAACTCATTGTTTTACCCACCACCGAGAATTACC TTAAAGTTAAAAATGCCCAGATCAGCTGCAGAAGACTGCAGAAACAGCTC TACAGAAACTGACCAACAATCCCACTCTACTGACAGTGGCTCCCCTGTTC ACAGTGTAAAGAGCATGCAGGTACCTCAGGAGTCACTAGAAATGAGAATG AAACCATATCCAAGGTACTCACTAGAAAGCAAGAATAATGGTTTGCTGGC CAGCCTCAACCATTCTAGGAGTGAAGAAAAGGATTCCAGTCCTGCTTGGA AAGCTCCATCTTCAGAGTTCTATCATGGGCAGTCATTGGGCAAACCTCTG GCCTTTCAGGCTGCCATCCATGGACAGTCTACTGTTGGGAATGGGAAAAG TCAACCAAACTCCAAGTTTACCAGATCCAATGGTCTGGAGGGCAGCTGGT CTGGGAATGTCACCCAAAAAGATAGCTCGAGTGAGATGTTCTATAACCAG GAGTCTATGCTTGGCTCCCACTTGGTCAGTCAGGGAAACTTGAGAAAATC TACCATGGAACACTTCAGCAGATCATTCAAGGAGGCCACCAACAGGTGGA TGAGAACCACAGCAGACCTCCAGTGCTATGTGAAGCCAACCAAGAATATG AGCCCCAAGGAGCAGTGCTGGGGTAGGCAGCTTCTCAGGCGGTCTGCAGG GAAAGCTCCATATCAGGAAAACGATGGATATTGCCCAGATTTGGAGCCGA GTGATTCAGAAGCAGAAGGTGATGAGAGTAAAGGAAAAGTCAGGGTAAGG AGAGATAACTCGGACAGGGAAAATCCTTCCCATGACTCCAGACGAGATTG TCACGTTAAAAACAAGACACAT |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 823 | 41 | 814 | Insert and frame-shift 807-808:C-H^T |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
AlaGluValPheArgLysAspLeuIleSerAlaMetLysLeuProAspSerHisHisIle
||||||||||||||||||||||||||||||||||||||||||||||||||||||
SerGlnValPheArgLysAspLeuIleSerAlaMetLysLeuProAspSerHisHisIle
TCCCAGGTGTTCCGGAAGGACCTCATCAGTGCCATGAAACTTCCAGATTCTCACCACATT
AsnProAspSerTyrTyrLeuPheAlaAspThrTrpLysGluGluTrpGluLysGlyVal
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
AsnProAspSerTyrTyrLeuPheAlaAspThrTrpLysGluGluTrpGluLysGlyVal
AATCCTGACAGTTATTACCTCTTTGCGGATACATGGAAGGAAGAATGGGAAAAGGGAGTC
GlnValProAlaSerProAspThrValProGlnProSerLeu{Ar} >>>> Target
||||||||| |||||||||||||||||| |||||||||{||} 121
GlnValProValSerProAspThrValProGluProSerLeu{Ar}++
CAGGTACCAGTCAGTCCAGACACTGTTCCAGAGCCTTCTCTC{AG}gt
Intron 1 >>>> {g}IleIleAlaGluLysValLysAspValLeuPheIleArgPro
11 bp {|}||||||||||||||| |||||||||||||||||| |||
++{g}IleIleAlaGluLysGluLysAspValLeuPheIleGlnPro
ag{G}ATTATAGCTGAAAAGGAAAAAGATGTTTTGTTTATTCAACCT
ArgLysTyrIleHisCysSerSerProAspThrThrGluProGlyTyrIleAsnIleMet
|||||||||||| |||||| ||| |||||||||||| |||||||||
ArgLysTyrIleArgCysSerThrProGluAlaThrGluProGlySerIleAsnIleSer
CGGAAATATATCCGCTGTTCTACACCAGAGGCCACAGAACCTGGCTCTATCAACATCTCG
GluLeuAlaAlaSerValCysArgTyrAspLeuAspAspMetAspIlePheTrpLeuGln
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||
HisLeuAlaAlaSerValCysArgTyrAspLeuAspAspMetAspIlePheTrpLeuGln
CATCTGGCAGCATCTGTATGCCGCTATGACCTGGATGACATGGACATCTTCTGGCTCCAG
GluLeuAsnGluAspLeuAlaGluMet{G} >>>> Target Intron 2 >>>> {
|||||||||||||||||| |||{|} 2946 bp {
GluLeuAsnGluAspLeuThrGlnMet{G}++ ++{
GAACTCAATGAAGACCTTACACAAATG{G}gt ag{
ly}CysGlyProValAspGluAsnLeuMetGluLysThrValGluValLeuGluArgHis
||}||| |||||||||||| ||||||||||||||||||||||||||||||||||||
ly}CysGluProValAspGluThrLeuMetGluLysThrValGluValLeuGluArgHis
GT}TGTGAGCCAGTTGATGAGACTCTTATGGAAAAGACAGTAGAAGTCCTGGAACGTCAT
CysHisGluAsnMetAsnHisAlaIleGluThrGluGluGlyLeuGlyIleGluTyrAsp
||||||||||||||||||||||||||| ||||||||||||||||||||||||||||||
CysHisGluAsnMetAsnHisAlaIleLysThrGluGluGlyLeuGlyIleGluTyrAsp
TGCCATGAAAATATGAACCATGCTATTAAGACAGAGGAAGGGCTAGGCATAGAGTATGAT
GluAspValIleCysAspValCysArgSerProAspSerGluGluGlyAsnAspMetVal
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GluAspValIleCysAspValCysArgSerProAspSerGluGluGlyAsnAspMetVal
GAAGATGTGATCTGTGATGTGTGCCGGTCTCCAGACAGTGAAGAAGGGAATGATATGGTA
PheCysAspLysCysAsnValCysValHisGln >>>> Target Intron 3 >>>>
|||||||||||||||||| |||||||||||| 7501 bp
PheCysAspLysCysAsnIleCysValHisGln++
TTCTGTGATAAGTGTAACATCTGTGTGCATCAGgt
AlaCysTyrGlyIleLeuLysValProGluGlySerTrpLeuCysArgSerCysValL
|||||||||||||||||||||||||||||||||||||||||||||||| ||||||
++AlaCysTyrGlyIleLeuLysValProGluGlySerTrpLeuCysArgAlaCysValM
agGCCTGCTATGGCATCCTTAAGGTTCCAGAAGGCAGCTGGCTATGTCGTGCCTGTGTCA
euGlyIleTyrProGlnCysValLeuCysProLysLysGlyGlyAlaLeuLysThrThrL
|||||| ||||||||| |||||||||||| ||||||||| |||||||||
etGlyIleHisProGlnCysLeuLeuCysProLysThrGlyGlyAlaMetLysThrThrA
TGGGCATTCATCCTCAGTGTCTGTTATGTCCAAAGACTGGTGGAGCCATGAAGACCACCA
ysThrGlyThrLysTrpAlaHisValSerCysAlaLeuTrpIleProGlu >>>> Tar
|||||| |||||||||||||||||||||||||||||||||||||||
rgThrGlyAspLysTrpAlaHisValSerCysAlaLeuTrpIleProGlu++
GGACAGGGGATAAATGGGCTCATGTCAGCTGTGCCCTGTGGATTCCAGAGgt
get Intron 4 >>>> ValSerIleAlaCysProGluArgMetGluProIleThrLy
11335 bp ||| |||||||||||||||||||||||||||||||||||
++ValAsnIleAlaCysProGluArgMetGluProIleThrLy
agGTCAACATTGCTTGTCCTGAGAGGATGGAACCAATTACAAA
sIleSerHisIleProProSerArgTrpAlaLeuValCysAsnLeuCysLysLeuLysTh
|||||||||||||||||||||||||||||||||||||||||||||||||||| |||||
sIleSerHisIleProProSerArgTrpAlaLeuValCysAsnLeuCysLysMetLysTh
GATCTCTCACATCCCACCCAGTCGGTGGGCCTTAGTCTGCAACCTGTGCAAGATGAAAAC
rGlyAlaCysIleGln >>>> Target Intron 5 >>>> CysSerIleLysSer
|||||||||||||||| 10221 bp |||||| ||||||
rGlyAlaCysIleGln++ ++CysSerValLysSer
AGGAGCTTGCATTCAGgt agTGCTCAGTGAAAAGC
CysIleThrAlaPheHisValThrCysAlaPheGluHisGlyLeuGluMetLysThrIle
||||||||||||||||||||||||||||||||||||||| ||||||||||||||||||
CysIleThrAlaPheHisValThrCysAlaPheGluHisAsnLeuGluMetLysThrIle
TGTATAACTGCCTTCCATGTCACCTGTGCCTTTGAGCACAATCTCGAGATGAAGACCATT
LeuAspGluGlyAspGluValLysPheLysSerTyrCysLeuLysHisSerGlnAsnArg
|||||| ||||||||||||||||||||||||||||||||||||||||||||||||
LeuAspAspGluAspGluValLysPheLysSerTyrCysLeuLysHisSerGlnAsnArg
CTAGATGATGAGGATGAAGTGAAGTTCAAATCATACTGTCTTAAACATAGCCAAAACAGA
GlnLysLeuGlyGluAlaGluTyrProHisHisArgAlaLysGluGlnSerGlnAlaLys
|||||| |||||||||||||||||||||||| ||| ||||||||||||||||||
GlnLysIleGlyGluAlaGluTyrProHisHisTrpAlaAlaGluGlnSerGlnAlaLys
CAGAAGATTGGGGAAGCTGAGTACCCCCACCACTGGGCTGCAGAGCAAAGCCAAGCTAAA
SerGluLysThrSerLeuArgAlaGlnLysLeuArgGluLeuGluGluGluPheTyrSer
|||||||||||||||||||||||||||||||||||||||||||||||| ||||||
SerGluLysThrSerLeuArgAlaGlnLysLeuArgGluLeuGluGluAspPheTyrThr
AGTGAGAAAACTAGCCTGCGGGCCCAGAAGCTTCGGGAGCTAGAAGAGGACTTCTACACC
LeuValArgValGluAspValAlaAlaGluLeuGlyMetProThrLeuAlaValAspPhe
|||||||||||||||||||||||| |||||| ||| ||| |||||||||
LeuValArgValGluAspValAlaLysGluLeuGluLeuProMetLeuValValAspPhe
CTGGTCCGAGTAGAAGATGTGGCCAAAGAACTGGAGCTGCCCATGCTAGTTGTGGATTTT
IleTyrAsnTyrTrpLysLeuLysArgLysSerAsnPheAsnLysProLeuPheProPro
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
IleTyrAsnTyrTrpLysLeuLysArgLysSerAsnPheAsnLysProLeuPheProPro
ATCTATAACTACTGGAAACTAAAGCGTAAAAGTAACTTCAATAAGCCATTATTCCCTCCA
LysGluAspGluGluAsnGlyLeuValGlnProLysGluGluSerIleHisThrArgMet
|||||||||||| |||||||||||||||||||||||||||||| ||||||||||||
LysGluAspGluGlyAsnGlyLeuValGlnProLysGluGluSerValHisThrArgMet
AAGGAGGACGAAGGAAATGGCCTGGTACAGCCAAAAGAGGAAAGTGTTCACACTCGTATG
ArgMetPheMetHisLeuArgGlnAspLeuGluArg >>>> Target Intron 6 >
|||||||||||||||||||||||||||||||||||| 1474 bp
ArgMetPheMetHisLeuArgGlnAspLeuGluArg++
AGAATGTTTATGCACCTTCGGCAAGACTTGGAAAGGgt
>>> ValArgAsnLeuCysTyrMetIleSerArgArgGluLysLeuLysLeuSerHisA
||||||||||||||||||||||||||||||||||||||| |||||||||
++ValArgAsnLeuCysTyrMetIleSerArgArgGluLysMetLysLeuSerGlnS
agGTCCGAAATCTGTGCTACATGATAAGCAGACGAGAGAAGATGAAATTGTCACAGA
snLysIleGlnGluGlnIlePheGlyLeuGlnValGlnLeuLeuAsnGlnGluIleAspA
||||||||||||||||||||||||||||||||| ||||||||| |
erArgLeuGlnGluGlnIlePheGlyLeuGlnValGlnLeuValAsnGlnGluMetAlaA
GCAGGCTACAGGAACAGATCTTCGGTTTGCAGGTTCAGCTTGTTAACCAAGAAATGGCTG
la{G} >>>> Target Intron 7 >>>> {ly}LeuProLeuThrAsnAlaLeuG
||{|} 1793 bp {||}||||||||||||||| ||||
la{G}++ ++{ly}LeuProLeuThrAsnThrLeuG
CA{G}gt ag{GA}CTTCCTTTGACCAATACACTAG
luAsnSerLeuPheTyrProProProArgIleThrLeuLysLeuLysMetProLysSerT
||||||||||||||||||||||||||||||||||||||||||||||||||||| |||
luAsnSerLeuPheTyrProProProArgIleThrLeuLysLeuLysMetProArgSerA
AAAACTCATTGTTTTACCCACCACCGAGAATTACCTTAAAGTTAAAAATGCCCAGATCAG
hrProGluAspHisArgAsnSerSerThrGluThrAspGlnGlnProHisSerProAspS
|||||| |||||||||||||||||||||||||||||| |||||| ||||
laAlaGluAspCysArgAsnSerSerThrGluThrAspGlnGlnSerHisSerThrAspS
CTGCAGAAGACTGCAGAAACAGCTCTACAGAAACTGACCAACAATCCCACTCTACTGACA
erSerSerSerValHisSerIleArgAsnMetGlnValProGlnGluSerLeuGluMetA
|| ||| ||||||||| |||||||||||||||||||||||||||||||
erGlySerProValHisSerValLysSerMetGlnValProGlnGluSerLeuGluMetA
GTGGCTCCCCTGTTCACAGTGTAAAGAGCATGCAGGTACCTCAGGAGTCACTAGAAATGA
rgThrLysSerTyrProArgTyrProLeuGluSerLysAsnAsnArgLeuLeuAlaSerL
|| ||| |||||||||||| |||||||||||||||||| |||||||||||||
rgMetLysProTyrProArgTyrSerLeuGluSerLysAsnAsnGlyLeuLeuAlaSerL
GAATGAAACCATATCCAAGGTACTCACTAGAAAGCAAGAATAATGGTTTGCTGGCCAGCC
euSerHisSerArgSerGluAlaLysGluSerSerProAlaTrpArgThrProSerSerG
|| ||||||||||||||| ||| ||||||||||||||| ||||||||||
euAsnHisSerArgSerGluGluLysAspSerSerProAlaTrpLysAlaProSerSerG
TCAACCATTCTAGGAGTGAAGAAAAGGATTCCAGTCCTGCTTGGAAAGCTCCATCTTCAG
luCysTyrHisGlyGlnSerLeuGlyLysProLeuValLeuGlnAlaAlaLeuHisGlyG
|| |||||||||||||||||||||||||||||| ||||||||| |||||||
luPheTyrHisGlyGlnSerLeuGlyLysProLeuAlaPheGlnAlaAlaIleHisGlyG
AGTTCTATCATGGGCAGTCATTGGGCAAACCTCTGGCCTTTCAGGCTGCCATCCATGGAC
lnSerSerIleGlyAsnGlyLysSerGlnProAsnSerLysPheAlaLysSerAsnGlyL
||||| ||||||||||||||||||||||||||||||||| ||||||||||
lnSerThrValGlyAsnGlyLysSerGlnProAsnSerLysPheThrArgSerAsnGlyL
AGTCTACTGTTGGGAATGGGAAAAGTCAACCAAACTCCAAGTTTACCAGATCCAATGGTC
euGluGlySerTrpSerGlyAsnValThrGlnLysAspSerSerSerGluMetPheCysA
||||||||||||||||||||||||||||||||||||||||||||||||||||||||
euGluGlySerTrpSerGlyAsnValThrGlnLysAspSerSerSerGluMetPheTyrA
TGGAGGGCAGCTGGTCTGGGAATGTCACCCAAAAAGATAGCTCGAGTGAGATGTTCTATA
spGlnGluProValPheSerProHisLeuValSerGlnGlySerPheArgLysSerThrV
|||||| |||||||||||||||||| ||||||||||||
snGlnGluSerMetLeuGlySerHisLeuValSerGlnGlyAsnLeuArgLysSerThrM
ACCAGGAGTCTATGCTTGGCTCCCACTTGGTCAGTCAGGGAAACTTGAGAAAATCTACCA
alGluHisPheSerArgSerPheLysGluThrThrAsnArgTrpValLysAsnThrGluA
||||||||||||||||||||||||||| |||||||||||| ||| |
etGluHisPheSerArgSerPheLysGluAlaThrAsnArgTrpMetArgThrThrAlaA
TGGAACACTTCAGCAGATCATTCAAGGAGGCCACCAACAGGTGGATGAGAACCACAGCAG
spLeuGlnCysTyrValLysProThrLysAsnMetSerProLysGluGlnPheTrpGlyA
|||||||||||||||||||||||||||||||||||||||||||||||||| |||||||
spLeuGlnCysTyrValLysProThrLysAsnMetSerProLysGluGlnCysTrpGlyA
ACCTCCAGTGCTATGTGAAGCCAACCAAGAATATGAGCCCCAAGGAGCAGTGCTGGGGTA
rgGlnValLeuArgArgSerAlaGlyArgAlaProTyrGlnGluAsnAspGlyTyrCysP
||||| |||||||||||||||||| |||||||||||||||||||||||||||||||
rgGlnLeuLeuArgArgSerAlaGlyLysAlaProTyrGlnGluAsnAspGlyTyrCysP
GGCAGCTTCTCAGGCGGTCTGCAGGGAAAGCTCCATATCAGGAAAACGATGGATATTGCC
roAspLeuGluLeuSerAspSerGluAlaGluSerAspGlyAsnLysGluLysValArgV
||||||||||| |||||||||||||||||| ||| ||| ||||||||||
roAspLeuGluProSerAspSerGluAlaGluGlyAspGluSerLysGlyLysValArgV
CAGATTTGGAGCCGAGTGATTCAGAAGCAGAAGGTGATGAGAGTAAAGGAAAAGTCAGGG
alArgLysAspSerSerAspArgGluAsnProProHisAspSerArgArgAspCys-His
||||| ||| |||||||||||||||||| |||||||||||||||||||||#|||
alArgArgAspAsnSerAspArgGluAsnProSerHisAspSerArgArgAspCys#His
TAAGGAGAGATAACTCGGACAGGGAAAATCCTTCCCATGACTCCAGACGAGATTGTTCAC
GlyLysSerLysThrHis
||| |||||||||
ValLysAsnLysThrHis
GTTAAAAACAAGACACAT
//
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