| Basic information |
| Official Symbol | PEX10 |
| Description | peroxisomal biogenesis factor 10 |
| Other Aliases | NALD, PBD6A, PBD6B, RNF69 |
| Other Description | RING finger protein 69; peroxin 10; peroxin-10; peroxisome assembly protein 10; peroxisome biogenesis factor 10 |
| Mutation type | premature termination 206:D->TGA, premature termination 220:Q->TAG |
| Location | Scaffold138365_1:127621 117443 - |
| Wiki | Wikipedia GeneCard |
| Sequence |
| PEX10 |
ATGGCACCTGCCGGCGCCAGTCCCCCGGAGGTGATCCGCGCGGCGCAGAA GGACGAGTACTACTGCGGGGGCCTGCGGAGCGCGGCGGGCGGGGCCCTGC ACAGCTTAGCGGGTGCAAAGAAATGGCTGGAATGGAGGAAAGAGATCGAG CTGCTCTCGGACGTGGCCTACTTTGGTCTCACCACACTTGCAGGCTATCA GACTCTCGGGGAGGAGTATGTCAGCATTGTCCAGGTGGACCCATCCCAGA GGCGCGTGCCCTCCAGGTTTCGCCGTGGTGTGCTGATTGCCCTGCACACT GTCCTGCCCTACCTGCTGGACAAGGCCCTGCTCCCTCTGGAGCAGGAGCT ACAGGCTGACGGTGACAGCACCCGGCCCTCACAAGGCAGCTTGGTTCCTG GCAGCCGTGGCCGGTCAGGGGCACGGCGCTGGGTGCGTCGCCATGTGGCC ACCTTGACAGAGCAGCAACGGAGGACACTCCAGCGGGCAGCTTTTGTCCT CCGGCAAGGCCTCACCTGCCTCCAGCGACTCCACATTGCCTGGTTTTACA TCAACGGTGCCTTCTACCACCTGGCCAAGAGGCTCACGGGGATCACTTAC GTAAGTAGCAGGTGCTGAGCGGGCACTGCCACGCTATGGGTTGTCCATCT GCTTTCATAGCTCCGCGTCAGCCACCTGCCTGGAGAGGACCTGAGGGCTC GCACAAGCTACCAGCTGCTGGGGTTCATCTCCCTCTTCCACCTGGCGCTC TCCGTGGGGCTGCAGCTGTACAGCTTCAGGCAGAGACAGCGAGCCAGGAA GGAGTGGAGGCTGCACCGCAACCTGTCTCACCGCAGGAGCTCTCTGGAAG AAAGAGCAGTTCCCAGAAACCCACTCTGCACCCTGTGCCTGGAGGAACGG AGGCATTCGACAGCCACGCCCTGCGGCCACCTGTTCTGCTGGGAGTGTAT CACCGAGTGGTGTAGCACCAAGACGGAGTGTCCCCTTTGCAGGGAGAAGT TTCCTCCCCAGAAGCTCGTCTACCTAAGGCACTACCGC |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 346 | 1 | 346 | Premature termination 206:D->TGA, Premature termination 220:Q->TAG |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
MetAlaProAlaAlaAlaSerProProGluValIleArgAlaAlaGlnLysAspGluTyr
|||||||||||| |||||||||||||||||||||||||||||||||||||||||||||
MetAlaProAlaGlyAlaSerProProGluValIleArgAlaAlaGlnLysAspGluTyr
ATGGCACCTGCCGGCGCCAGTCCCCCGGAGGTGATCCGCGCGGCGCAGAAGGACGAGTAC
TyrArgGlyGlyLeuArgSerAlaAlaGlyGlyAlaLeuHisSerLeuAla{G} >>>>
||| |||||||||||||||||||||||||||||||||||||||||||||{|}
TyrCysGlyGlyLeuArgSerAlaAlaGlyGlyAlaLeuHisSerLeuAla{G}++
TACTGCGGGGGCCTGCGGAGCGCGGCGGGCGGGGCCCTGCACAGCTTAGCG{G}gt
Target Intron 1 >>>> {ly}AlaArgLysTrpLeuGluTrpArgLysGluVal
4218 bp {||}||| ||||||||||||||||||||||||
++{ly}AlaLysLysTrpLeuGluTrpArgLysGluIle
ag{GT}GCAAAGAAATGGCTGGAATGGAGGAAAGAGATC
GluLeuLeuSerAspValAlaTyrPheGlyLeuThrThrLeuAla{G} >>>> Targe
|||||||||||||||||||||||||||||||||||||||||||||{|} 2
GluLeuLeuSerAspValAlaTyrPheGlyLeuThrThrLeuAla{G}++
GAGCTGCTCTCGGACGTGGCCTACTTTGGTCTCACCACACTTGCA{G}gt
t Intron 2 >>>> {ly}TyrGlnThrLeuGlyGluGluTyrValSerIleIleGln
247 bp {||}||||||||||||||||||||||||||||||||| |||
++{ly}TyrGlnThrLeuGlyGluGluTyrValSerIleValGln
ag{GC}TATCAGACTCTCGGGGAGGAGTATGTCAGCATTGTCCAG
ValAspProSerArgIleHisValProSerSerLeuArgArgGlyValLeuValThrLeu
|||||||||||| ||||||||| ||||||||||||||| |||
ValAspProSerGlnArgArgValProSerArgPheArgArgGlyValLeuIleAlaLeu
GTGGACCCATCCCAGAGGCGCGTGCCCTCCAGGTTTCGCCGTGGTGTGCTGATTGCCCTG
HisAlaValLeuProTyrLeuLeuAspLysAlaLeuLeuProLeuGluGlnGluLeuGln
||| ||||||||||||||||||||||||||||||||||||||||||||||||||||||
HisThrValLeuProTyrLeuLeuAspLysAlaLeuLeuProLeuGluGlnGluLeuGln
CACACTGTCCTGCCCTACCTGCTGGACAAGGCCCTGCTCCCTCTGGAGCAGGAGCTACAG
AlaAspProAspSerGlyArgProLeuGlnGlySerLeuGlyProGlyGlyArgGlyCys
|||||| |||||| |||||| |||||||||||| |||||| ||||||
AlaAspGlyAspSerThrArgProSerGlnGlySerLeuValProGlySerArgGlyArg
GCTGACGGTGACAGCACCCGGCCCTCACAAGGCAGCTTGGTTCCTGGCAGCCGTGGCCGG
SerGlyAlaArgArgTrpMetArgHisHisThrAlaThrLeuThrGluGlnGlnArgArg
|||||||||||||||||| ||| ||| |||||||||||||||||||||||||||
SerGlyAlaArgArgTrpValArgArgHisValAlaThrLeuThrGluGlnGlnArgArg
TCAGGGGCACGGCGCTGGGTGCGTCGCCATGTGGCCACCTTGACAGAGCAGCAACGGAGG
AlaLeuLeuArgAlaValPheValLeuArgGlnGlyLeuAlaCysLeuGlnArgLeuHis
||| |||||| ||||||||||||||||||||| ||||||||||||||||||
ThrLeuGlnArgAlaAlaPheValLeuArgGlnGlyLeuThrCysLeuGlnArgLeuHis
ACACTCCAGCGGGCAGCTTTTGTCCTCCGGCAAGGCCTCACCTGCCTCCAGCGACTCCAC
ValAlaTrpPheTyrIleHisGlyValPheTyrHisLeuAlaLysArgLeuThrGlyIle
||||||||||||||| ||| |||||||||||||||||||||||||||||||||
IleAlaTrpPheTyrIleAsnGlyAlaPheTyrHisLeuAlaLysArgLeuThrGlyIle
ATTGCCTGGTTTTACATCAACGGTGCCTTCTACCACCTGGCCAAGAGGCTCACGGGGATC
ThrTyrGlnAlaLeuArgProAspProLeuArgValLeu{Me} >>>> Target Int
|||||| ||| { } 1417 b
ThrTyrValSerSerArgCys***AlaGlyThrAlaThr{Le}+-
ACTTACGTAAGTAGCAGGTGCTGAGCGGGCACTGCCACG{CT}gc
ron 3 >>>> {t}SerValAlaProSerAlaLeuGlnLeuArgValArgSerLeuPro
p { } ||| ||||||||| ||||||
-+{u}TrpValValHisLeuLeuSer***LeuArgValSerHisLeuPro
tg{A}TGGGTTGTCCATCTGCTTTCATAGCTCCGCGTCAGCCACCTGCCT
GlyGluAspLeuArgAlaArgValSerTyrArgLeuLeuGlyValIleSerLeuLeuHis
||||||||||||||||||||| |||||| ||||||||| ||||||||| |||
GlyGluAspLeuArgAlaArgThrSerTyrGlnLeuLeuGlyPheIleSerLeuPheHis
GGAGAGGACCTGAGGGCTCGCACAAGCTACCAGCTGCTGGGGTTCATCTCCCTCTTCCAC
LeuValLeuSerMetGlyLeuGlnLeuTyrGlyPheArgGlnArgGlnArgAlaArgLys
||| |||||| ||||||||||||||| |||||||||||||||||||||||||||
LeuAlaLeuSerValGlyLeuGlnLeuTyrSerPheArgGlnArgGlnArgAlaArgLys
CTGGCGCTCTCCGTGGGGCTGCAGCTGTACAGCTTCAGGCAGAGACAGCGAGCCAGGAAG
GluTrpArgLeuHisArgGlyLeuSerHisArg{Ar} >>>> Target Intron 4
|||||||||||||||||| ||||||||||||{||} 109 bp
GluTrpArgLeuHisArgAsnLeuSerHisArg{Ar}++
GAGTGGAGGCTGCACCGCAACCTGTCTCACCGC{AG}gt
>>>> {g}AlaSerLeuGluGluArgAlaValSerArgAsnProLeuCysThrLeuCys
{|} ||||||||||||||||||||| ||||||||||||||||||||||||
++{g}SerSerLeuGluGluArgAlaValProArgAsnProLeuCysThrLeuCys
ag{G}AGCTCTCTGGAAGAAAGAGCAGTTCCCAGAAACCCACTCTGCACCCTGTGC
LeuGluGluArgArgHisProThrAlaThrProCysGlyHisLeuPheCysTrpGluCys
|||||||||||||||||| |||||||||||||||||||||||||||||||||||||||
LeuGluGluArgArgHisSerThrAlaThrProCysGlyHisLeuPheCysTrpGluCys
CTGGAGGAACGGAGGCATTCGACAGCCACGCCCTGCGGCCACCTGTTCTGCTGGGAGTGT
IleThrAlaTrpCysSerSerLys >>>> Target Intron 5 >>>> AlaGluC
|||||| ||||||||| ||| 1150 bp ||||
IleThrGluTrpCysSerThrLys++ ++ThrGluC
ATCACCGAGTGGTGTAGCACCAAGgt agACGGAGT
ysProLeuCysArgGluLysPheProProGlnLysLeuIleTyrLeuArgHisTyrArg
|||||||||||||||||||||||||||||||||||||| ||||||||||||||||||
ysProLeuCysArgGluLysPheProProGlnLysLeuValTyrLeuArgHisTyrArg
GTCCCCTTTGCAGGGAGAAGTTTCCTCCCCAGAAGCTCGTCTACCTAAGGCACTACCGC
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