| Basic information |
| Official Symbol | MYT1 |
| Description | myelin transcription factor 1 |
| Other Aliases | C20orf36, MTF1, MYTI, PLPB1 |
| Other Description | myelin transcription factor I; proteolipid protein binding protein; proteolipid protein-binding protein |
| Mutation type | premature termination 618:P->TAG, premature termination 632:S->TAG |
| Location | Scaffold144472_1:1225782 1258279 + |
| Wiki | Wikipedia GeneCard |
| Sequence |
| MYT1 |
AGCTGTCCCACCCCAGGGTGCACAGGCTCAGGACATGTCCGAGGCAAGTA CTCCAGACACCGAAGTTTACAGAGCTGCCCTCTGGCCAAGAAGAGGAAGC TGGCGGGTGCTGAGGCTGAGCACCTGGTGTCCAAGAGGAAGTCGCAGCCC CTGAAGCTGGCTCTGGGCGAGGGCTACGGCGTGGACAGCGAGGACAGTGA GGAGGCTGAGGTGAAGGGTGCCTCTGTTTCGGATGAATCGGAAGGGACTC TGGAGGAGGCCGAGGCCGGGATGTCAGGACAGGAGGAGATTCATCGCCCC GAACCAGCTGAAGGAAGAAGCCCCACCAAGGCCCATTTGGGATCCAACCC CATCAGCAGCGCCACTGGCTCCTCCCAGGGTAGCTATCGCAGTTACCAGG GGGTCATTGCCACCTCTCTCCTGCACTTGGGCCAAATTGTCCAGGAGGCC CGGGATGGGGAGGAGGCAGGCCAGGCAGTTGAGCCGGTGCCCGGTGTTGT GCACTTGCTGCCAGCAGAGGGGGCCACCAGCGATGAGGGTGAGAAGGACC TCTTCATCCAGCCAGAAGACGCAGAGGAAGTCATCGAAGTCACCAGCGAG CGTTCCCAAGAGCCATGTCCTCAGTCCCTGGCTGATGCAGCCGTTGAAGG GTCCAGCAAACAGAAAGGCATCCTGGGTCATGAAGAGGAGGATGAGGAGG AAGAAGAGGAGGAGGATGAGGAGGAAGAGGAAGAAGAGGAGGAAGAGGAG GAAGAAGATGAAGAGGAAGAGGAGGAGGAGGAAGAGGAGGAAGAGGAAGG GGAGGAGGGGTCAGCCCCAGATGTAATCTTTGAGGAGGGTGCCTCCCATG CCTCTGTCCAGCAGGCCCCTGAGCCTCCCAGCCCCAGGCCGGAGTACTCT GTGGTTGTGGAGGTCCGCTCCGACGAGGACAAAGAGGAAGACTCCCGCTC CCAGAAGTCCGCAGTCACCGACGAGTTGGAGATGTACGATGTGCTGACCC GTGGGAACCTGGGCCTCCTGGAGCAGGCGATCGCTCTGAAGGCGGAGCAG GTGCGTGCAGTCTGCGAGCCGGGCTGCCCACCCACCGAGCAGGGCCAGCT GGGCCCTGGCGAGCCAGGGAAGGCAGCGAAGCCCCTGGACACCGTGCGCA AGAGCTACTACAGCAAAGACCCTTCGAGAACGGAGAAGCGTGAGATTAAG TGTCCGACGCCAGGCTGTGACGGCACCGGCCATGTGACTGGGCTGTACCC TCACCACCGCAGCCTGTCTGGCTGTCCCCACAAGGACAGGATCCCCCCAG AGATCTTGGCCATGCATGAGAATGTGCTGAAGTGCCCCACCCCTGGCTGC ACGGGCCAGGGCCACGTGAACAGCAACCGCAACACACACAGGAGCTTGTC TGGATGTCCTATTGCAGCTGCCGAGAAATTAGCCAAATCTCATGAGAAGC AGCAGCCACAGACCGGAGACGCTTCCAAGAGCAGCCCCAGCTCAGATCGA ATCCTCAGGCCCATGTGCTTCGTGAAGCAGCTGGACGCCCCTCCATATGG GAGCTACAGGCCCAGCGCAGCCCCTGCCACGCCCAGGGCCAACTTGGCCA AGGAGCTGGAGAAGTTCTCCAAGGTCACCTTTGACTACGCAAGTTTCGAT GCTCAGGTTTTTGGCAAACGCATGCTTGCCCCAAAGATTCAGACCAGTGA AACCTCACCTAAAGCCTTTCAATGTAAGTAGGGGAGAATCGTTTCTCTTC CACAGCCCTCTGGTAGTCAGTAGTCGTGTGAGACACCCTCCCCCTCTTCT GCAGGCTTCGACTACTCACATGATGCCGAGGCTGCACACATGGCCGCCAC CGCCATCCTGAACCTCTCCACACGCTGCTGGGAGATGCCGGAGAACCTCA GCACGAAGCCACAGGACCTCCCCAGCAAGCCTGTGGACATCGAGGTGGAC GAGAATGGAACCCTGGACCTGAGCATGCACAAGCACCGCAGGCGGGACAA CGCCTTCCCGGGCGGTGGCAGCTGCAGCAGCAGCCCTGGTGTCAAGTCTC CTGACGCCTCCCAGCGCCAGAGCTGCGCCAGTGCTCCCAGCAGTTCCATG ACCTCTCCCCCATCCAGCCAGGCCTCCCGCCAGGATGAGTGGGACCGGCC CCTGGACTACACCAAGCCCAGCCGCCTGCGTGAGGAGGAGCCTGAGGAGT CAGAGCCTGCAGCCCATTCTTTTGCTTCTTCTGAAGCAGATGACCAGGAA GTGTCAGAAGAGAATTTCGAGGAGCGGAAGTACCCGGGGGAAGTCACCCT AACCAACTTTAAGCTGAAGTTTCTCTCCAAGGACATAAAGAAGGAGCTGC TCACCTGTCCCACCCCTGGCTGTGATGGCAGTGGCCACATCACCGGGAAC TATGCCTCCCACCGCAGCCTCTCTGGTTGCCCTCTTGCTGACAAGAGCCT CAGAAACCTCATGGCTGCCCACTCTGCTGACCTCAAGTGCCCCACGCCCG GCTGTGATGGCTCCGGTCACATAACAGGGAACTACGCTTCGCACCGGAGC TTGTCGGGCTGCCCTCGCGCCAAGAAGAGTGGAGTCAAGGTGGCACCCAC CAAGGACGATAAGGAGGACCCTGAGCTGATGAAGTGCCCAGTTCCAGGCT GCGTGGGGCTCGGTCACATCAGCGGCAAATACGCCTCTCACAGGAGTGCG TCCGGCTGCCCACTGGCTGCCCGGAGGCAGAAAGAGGGTTCCCTCAATGG CTCATCGTTCTCCTGGAAGTCGCTGAAGAACGAGGGGCCCACTTGCCCCA CCCCAGGCTGCGATGGTTCTGGCCACGCCAACGGGAGCTTCCTCACCCAC CGGAGTCTGTCTGGCTGTCCAAGAGCAACCTTTGCTGGAAAGAAGGGAAA ACTCTCAGGGGAGGAGGTTCTCAGTCCAAAGTTCAAGACCAGTGACGTGC TGGAGAATGACGAGGACATCAAACAGCTGAACCAGGAGATTCGAGACCTG AATGAGTCCAACTCGGAGATGGAGGCTGCCATGGTGCAGCTGCAGTCCCA GATCTCCTCCATGGAGAAGAATCTCAAGAGCATCGAGGAGGAGAACAAGC TAATCGAGGAGCAGAACGAGGCACTGTTTCTGGAGCTGTCTGGCCTGAGT CAGGCCCTCATCCAAAGTCTCGCCAACATCCGCCTTCCGCACATGGAGCC AATATGCGAACAGAATTTCGACGCCTACGTGAGCACCCTCACTGACATGT ACTCCAACCAGGAGTGCTACCAGGACCCGGAGCACAAGGACCTCTTGGAG AGCATCAAGCAGGCCGTGAGGGGCATCCAGGTC |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 1148 | 29 | 1148 | Premature termination 618:P->TAG, Premature termination 632:S->TAG |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
SerCysProThrProGlyCysThrGlySerGlyHisValArgGlyLysTyrSerArgHis
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
SerCysProThrProGlyCysThrGlySerGlyHisValArgGlyLysTyrSerArgHis
AGCTGTCCCACCCCAGGGTGCACAGGCTCAGGACATGTCCGAGGCAAGTACTCCAGACAC
Arg{Se} >>>> Target Intron 1 >>>> {r}LeuGlnSerCysProLeuAla
|||{||} 1427 bp {|}|||||||||||||||||||||
Arg{Se}++ ++{r}LeuGlnSerCysProLeuAla
CGA{AG}gt ag{T}TTACAGAGCTGCCCTCTGGCC
LysLysArgLysLeuGluGlyAlaGluAlaGluHisLeuValSerLysArgLysSerHis
||||||||||||||| |||||||||||||||||||||||||||||||||||||||
LysLysArgLysLeuAlaGlyAlaGluAlaGluHisLeuValSerLysArgLysSerGln
AAGAAGAGGAAGCTGGCGGGTGCTGAGGCTGAGCACCTGGTGTCCAAGAGGAAGTCGCAG
ProLeuLysLeuAlaLeuAspGluGlyTyrGlyValAspSerAspGlySerGluAspThr
|||||||||||||||||| ||||||||||||||||||||| ||||||
ProLeuLysLeuAlaLeuGlyGluGlyTyrGlyValAspSerGluAspSerGluGluAla
CCCCTGAAGCTGGCTCTGGGCGAGGGCTACGGCGTGGACAGCGAGGACAGTGAGGAGGCT
GluValLysAspAlaSerValSerAspGluSerGluGlyThrLeuGluGlyAlaGluAla
||||||||| |||||||||||||||||||||||||||||||||||| |||||||||
GluValLysGlyAlaSerValSerAspGluSerGluGlyThrLeuGluGluAlaGluAla
GAGGTGAAGGGTGCCTCTGTTTCGGATGAATCGGAAGGGACTCTGGAGGAGGCCGAGGCC
GluThrSerGlyGlnAspGluIleHisArgProGluThrAlaGlu{G} >>>> Targe
||||||||| |||||||||||||||||| ||||||{|} 2
GlyMetSerGlyGlnGluGluIleHisArgProGluProAlaGlu{G}++
GGGATGTCAGGACAGGAGGAGATTCATCGCCCCGAACCAGCTGAA{G}gt
t Intron 2 >>>> {ly}ArgSerProValLysSerHisPheGlySerAsnProIle
228 bp {||}||||||||| ||| ||| |||||||||||||||
++{ly}ArgSerProThrLysAlaHisLeuGlySerAsnProIle
ag{GA}AGAAGCCCCACCAAGGCCCATTTGGGATCCAACCCCATC
GlySerAlaThrAlaSerSerLysGlySerTyrSerSerTyrGlnGlyIleIleAlaThr
||||||||| |||||| ||||||||| |||||||||||| |||||||||
SerSerAlaThrGlySerSerGlnGlySerTyrArgSerTyrGlnGlyValIleAlaThr
AGCAGCGCCACTGGCTCCTCCCAGGGTAGCTATCGCAGTTACCAGGGGGTCATTGCCACC
SerLeuLeuAsnLeuGlyGlnIleAlaGluGluThrLeuValGluGluAspLeuGlyGln
||||||||| |||||||||||| ||| ||| ||||||
SerLeuLeuHisLeuGlyGlnIleValGlnGluAlaArgAspGlyGluGluAlaGlyGln
TCTCTCCTGCACTTGGGCCAAATTGTCCAGGAGGCCCGGGATGGGGAGGAGGCAGGCCAG
AlaAlaLysProGlyProGlyIleValHisLeuLeuGlnGluAlaAlaGluGlyAlaAla
||| ||| |||||| |||||||||||| ||||||||||||
AlaValGluProValProGlyValValHisLeuLeu------ProAlaGluGlyAlaThr
GCAGTTGAGCCGGTGCCCGGTGTTGTGCACTTGCTG------CCAGCAGAGGGGGCCACC
SerGluGluGlyGluLysGlyLeuPheIleGlnProGluAspAlaGluGluValValGlu
||| |||||||||||| ||||||||||||||||||||||||||||||||| |||
SerAspGluGlyGluLysAspLeuPheIleGlnProGluAspAlaGluGluValIleGlu
AGCGATGAGGGTGAGAAGGACCTCTTCATCCAGCCAGAAGACGCAGAGGAAGTCATCGAA
ValThrThrGluArgSerGlnAspLeuCysProGlnSerLeuGluAspAlaAlaSerGlu
|||||| |||||||||||| ||||||||||||||| ||||||||| |||
ValThrSerGluArgSerGlnGluProCysProGlnSerLeuAlaAspAlaAlaValGlu
GTCACCAGCGAGCGTTCCCAAGAGCCATGTCCTCAGTCCCTGGCTGATGCAGCCGTTGAA
GluSerSerLysGlnLysGlyIleLeuSerHisGluGluGluAspGluGluGluGluGlu
|||||||||||||||||||||||| ||||||||||||||||||||||||||||||
GlySerSerLysGlnLysGlyIleLeuGlyHisGluGluGluAspGluGluGluGluGlu
GGGTCCAGCAAACAGAAAGGCATCCTGGGTCATGAAGAGGAGGATGAGGAGGAAGAAGAG
GluGluGluGluGluGluGluAspGluGluGluGluGluGluGluGluGluGluGluGlu
|||||| |||||||||||||||||||||||||||||||||
GluGlu------------------AspGluGluGluGluGluGluGluGluGluGluGlu
GAGGAG------------------GATGAGGAGGAAGAGGAAGAAGAGGAGGAAGAGGAG
GluGluGluGluGluGluGluGluGluGluGluGluGluGluGluGluGluGluGluGlu
|||||| ||||||||||||||||||||||||||||||||||||||| ||||||
GluGluAspGluGluGluGluGluGluGluGluGluGluGluGluGluGlyGluGluGly
GAAGAAGATGAAGAGGAAGAGGAGGAGGAGGAAGAGGAGGAAGAGGAAGGGGAGGAGGGG
AlaAlaProAspValIlePheGlnGluAspThrSerHisThrSerAlaGlnLysAlaPro
|||||||||||||||||| ||| |||||| ||| ||| |||
SerAlaProAspValIlePheGluGluGlyAlaSerHisAlaSerValGlnGlnAla---
TCAGCCCCAGATGTAATCTTTGAGGAGGGTGCCTCCCATGCCTCTGTCCAGCAGGCC---
GluLeuArgGlyProGluSerProSerProLysProGluTyrSerValIleValGluVal
|||||| ||||||||| ||||||||||||||| |||||||||
------------ProGluProProSerProArgProGluTyrSerValValValGluVal
------------CCTGAGCCTCCCAGCCCCAGGCCGGAGTACTCTGTGGTTGTGGAGGTC
ArgSerAspAspAspLysAspGluAspThrHisSerArgLysSerThrValThrAspGlu
||||||||| |||||| |||||| ||| |||||| ||||||||||||
ArgSerAspGluAspLysGluGluAspSerArgSerGlnLysSerAlaValThrAspGlu
CGCTCCGACGAGGACAAAGAGGAAGACTCCCGCTCCCAGAAGTCCGCAGTCACCGACGAG
SerGluMetGlnAspMetMetThrArgGlyAsnLeuGlyLeuLeuGluGlnAlaIleAla
|||||| ||| |||||||||||||||||||||||||||||||||||||||
LeuGluMetTyrAspValLeuThrArgGlyAsnLeuGlyLeuLeuGluGlnAlaIleAla
TTGGAGATGTACGATGTGCTGACCCGTGGGAACCTGGGCCTCCTGGAGCAGGCGATCGCT
LeuLysAlaGluGlnValArgThrValCysGluProGlyCysProProAlaGluGlnSer
||||||||||||||||||||| |||||||||||||||||||||||| ||||||
LeuLysAlaGluGlnValArgAlaValCysGluProGlyCysProProThrGluGlnGly
CTGAAGGCGGAGCAGGTGCGTGCAGTCTGCGAGCCGGGCTGCCCACCCACCGAGCAGGGC
GlnLeuGlyLeuGlyGluProGlyLysAlaAlaLysProLeuAspThrValArgLysSer
||||||||| ||||||||||||||||||||||||||||||||||||||||||||||||
GlnLeuGlyProGlyGluProGlyLysAlaAlaLysProLeuAspThrValArgLysSer
CAGCTGGGCCCTGGCGAGCCAGGGAAGGCAGCGAAGCCCCTGGACACCGTGCGCAAGAGC
TyrTyrSerLys{A} >>>> Target Intron 3 >>>> {sp}ProSerArgAla
||||||||||||{|} 2120 bp {||}|||||||||
TyrTyrSerLys{A}++ ++{sp}ProSerArgThr
TACTACAGCAAA{G}gt ag{AC}CCTTCGAGAACG
GluLysArgGluIleLysCysProThrProGlyCysAspGlyThrGlyHisValThrGly
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GluLysArgGluIleLysCysProThrProGlyCysAspGlyThrGlyHisValThrGly
GAGAAGCGTGAGATTAAGTGTCCGACGCCAGGCTGTGACGGCACCGGCCATGTGACTGGG
LeuTyrProHisHisArgSerLeuSerGlyCysProHisLysAspArgIleProProGlu
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
LeuTyrProHisHisArgSerLeuSerGlyCysProHisLysAspArgIleProProGlu
CTGTACCCTCACCACCGCAGCCTGTCTGGCTGTCCCCACAAGGACAGGATCCCCCCAGAG
{I} >>>> Target Intron 4 >>>> {le}LeuAlaMetHisGluAsnValLeu
{|} 579 bp {||}||||||||||||||||||||||||
{I}++ ++{le}LeuAlaMetHisGluAsnValLeu
{A}gt ag{TC}TTGGCCATGCATGAGAATGTGCTG
LysCysProThrProGlyCysThrGlyGlnGlyHisValAsnSerAsnArgAsnThrHis
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
LysCysProThrProGlyCysThrGlyGlnGlyHisValAsnSerAsnArgAsnThrHis
AAGTGCCCCACCCCTGGCTGCACGGGCCAGGGCCACGTGAACAGCAACCGCAACACACAC
Arg{Se} >>>> Target Intron 5 >>>> {r}LeuSerGlyCysProIleAla
|||{||} 1090 bp {|}|||||||||||||||||||||
Arg{Se}++ ++{r}LeuSerGlyCysProIleAla
AGG{AG}gt ag{C}TTGTCTGGATGTCCTATTGCA
AlaAlaGluLysLeuAlaLysSerHisGluLysGlnGlnProGlnThrGlyAspProSer
|||||||||||||||||||||||||||||||||||||||||||||||||||||| |||
AlaAlaGluLysLeuAlaLysSerHisGluLysGlnGlnProGlnThrGlyAspAlaSer
GCTGCCGAGAAATTAGCCAAATCTCATGAGAAGCAGCAGCCACAGACCGGAGACGCTTCC
LysSerSerSerAsnSerAspArgIleLeu{Ar} >>>> Target Intron 6 >>>
||||||||| |||||||||||||||{||} 2582 bp
LysSerSerProSerSerAspArgIleLeu{Ar}++
AAGAGCAGCCCCAGCTCAGATCGAATCCTC{AG}gt
> {g}ProMetCysPheValLysGlnLeuGluValProProTyrGlySerTyrArgPro
{|}|||||||||||||||||||||||| ||||||||||||||||||||||||
++{g}ProMetCysPheValLysGlnLeuAspAlaProProTyrGlySerTyrArgPro
ag{G}CCCATGTGCTTCGTGAAGCAGCTGGACGCCCCTCCATATGGGAGCTACAGGCCC
AsnValAlaProAlaThrProArgAlaAsnLeuAlaLysGluLeuGluLysPheSerLys
||||||||||||||||||||||||||||||||||||||||||||||||||||||
SerAlaAlaProAlaThrProArgAlaAsnLeuAlaLysGluLeuGluLysPheSerLys
AGCGCAGCCCCTGCCACGCCCAGGGCCAACTTGGCCAAGGAGCTGGAGAAGTTCTCCAAG
ValThrPheAspTyrAlaSerPheAspAlaGlnValPheGlyLysArgMetLeuAlaPro
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ValThrPheAspTyrAlaSerPheAspAlaGlnValPheGlyLysArgMetLeuAlaPro
GTCACCTTTGACTACGCAAGTTTCGATGCTCAGGTTTTTGGCAAACGCATGCTTGCCCCA
LysIleGlnThrSerGluThrSerProLysAlaPheGlnSerLysProPheProLysAla
||||||||||||||||||||||||||||||||||||||| |||
LysIleGlnThrSerGluThrSerProLysAlaPheGlnCysLys***GlyArgIleVal
AAGATTCAGACCAGTGAAACCTCACCTAAAGCCTTTCAATGTAAGTAGGGGAGAATCGTT
SerSer{P} >>>> Target Intron 7 >>>> {ro}ArgHisSerProSerSer
||| {|} 1189 bp {||} ||| |||
SerLeu{P}-+ ++{ro}GlnProSerGlySerGln
TCTCTT{C}ct ag{CA}CAGCCCTCTGGTAGTCAG
SerTyrValArgSerThrSerSerSerSerAlaGlyPheAspTyrSerGlnAspAlaGlu
||| |||||||||||||||||||||||| |||||||||
***SerCysGluThrProSerProSerSerAlaGlyPheAspTyrSerHisAspAlaGlu
TAGTCGTGTGAGACACCCTCCCCCTCTTCTGCAGGCTTCGACTACTCACATGATGCCGAG
AlaAlaHisMetAlaAlaThrAlaIleLeuAsnLeuSerThrArgCysTrpGluMetPro
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
AlaAlaHisMetAlaAlaThrAlaIleLeuAsnLeuSerThrArgCysTrpGluMetPro
GCTGCACACATGGCCGCCACCGCCATCCTGAACCTCTCCACACGCTGCTGGGAGATGCCG
GluAsnLeuSerThrLysProGlnAspLeuProSerLys >>>> Target Intron
||||||||||||||||||||||||||||||||||||||| 461 bp
GluAsnLeuSerThrLysProGlnAspLeuProSerLys++
GAGAACCTCAGCACGAAGCCACAGGACCTCCCCAGCAAGgt
8 >>>> SerValAspIleGluValAspGluAsnGlyThrLeuAspLeuSerMetHisL
|||||||||||||||||||||||||||||||||||||||||||||||||
++ProValAspIleGluValAspGluAsnGlyThrLeuAspLeuSerMetHisL
agCCTGTGGACATCGAGGTGGACGAGAATGGAACCCTGGACCTGAGCATGCACA
ysHisArgLysArgGluAsnAlaPheProSerSerSerSerCysSerSerSerProGlyV
|||||||| ||| |||||||||||| ||||||||||||||||||||||
ysHisArgArgArgAspAsnAlaPheProGlyGlyGlySerCysSerSerSerProGlyV
AGCACCGCAGGCGGGACAACGCCTTCCCGGGCGGTGGCAGCTGCAGCAGCAGCCCTGGTG
alLysSerProAspAlaSerGlnArgHisSerSerThrSerAlaProSerSerSerMetT
|||||||||||||||||||||||||| ||| ||||||||||||||||||||||
alLysSerProAspAlaSerGlnArgGlnSerCysAlaSerAlaProSerSerSerMetT
TCAAGTCTCCTGACGCCTCCCAGCGCCAGAGCTGCGCCAGTGCTCCCAGCAGTTCCATGA
hrSerProGlnSerSerGlnAlaSerArgGlnAspGluTrpAspArgProLeuAspTyrT
|||||||| |||||||||||||||||||||||||||||||||||||||||||||||||
hrSerProProSerSerGlnAlaSerArgGlnAspGluTrpAspArgProLeuAspTyrT
CCTCTCCCCCATCCAGCCAGGCCTCCCGCCAGGATGAGTGGGACCGGCCCCTGGACTACA
hrLysProSerArgLeuArgGluGluGluProGluGlu >>>> Target Intron 9
|||||||||||||||||||||||||||||||||||||| 2340 bp
hrLysProSerArgLeuArgGluGluGluProGluGlu++
CCAAGCCCAGCCGCCTGCGTGAGGAGGAGCCTGAGGAGgt
>>>> SerGluProAlaAlaHisSerPheAlaSerSerGluAlaAspAspGlnGluVa
|||||||||||||||||||||||||||||||||||||||||||||||||||||
++SerGluProAlaAlaHisSerPheAlaSerSerGluAlaAspAspGlnGluVa
agTCAGAGCCTGCAGCCCATTCTTTTGCTTCTTCTGAAGCAGATGACCAGGAAGT
lSerGluGluAsnPheGluGluArgLysTyrProGlyGluValThrLeuThrAsnPheLy
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
lSerGluGluAsnPheGluGluArgLysTyrProGlyGluValThrLeuThrAsnPheLy
GTCAGAAGAGAATTTCGAGGAGCGGAAGTACCCGGGGGAAGTCACCCTAACCAACTTTAA
sLeuLysPheLeuSerLysAspIleLysLysGluLeuLeu{Th} >>>> Target In
||||||||||||||||||||||||||||||||||||||||{||} 936
sLeuLysPheLeuSerLysAspIleLysLysGluLeuLeu{Th}++
GCTGAAGTTTCTCTCCAAGGACATAAAGAAGGAGCTGCTC{AC}gt
tron 10 >>>> {r}CysProThrProGlyCysAspGlySerGlyHisIleThrGlyA
bp {|}|||||||||||||||||||||||||||||||||||||||||||
++{r}CysProThrProGlyCysAspGlySerGlyHisIleThrGlyA
ag{C}TGTCCCACCCCTGGCTGTGATGGCAGTGGCCACATCACCGGGA
snTyrAlaSerHisArg{Se} >>>> Target Intron 11 >>>> {r}LeuSer
|||||||||||||||||{||} 118 bp {|}||||||
snTyrAlaSerHisArg{Se}++ ++{r}LeuSer
ACTATGCCTCCCACCGC{AG}gt ag{C}CTCTCT
GlyCysProLeuAlaAspLysSerLeuArgAsnLeuMetAlaAlaHisSerAlaAspLeu
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GlyCysProLeuAlaAspLysSerLeuArgAsnLeuMetAlaAlaHisSerAlaAspLeu
GGTTGCCCTCTTGCTGACAAGAGCCTCAGAAACCTCATGGCTGCCCACTCTGCTGACCTC
{Ly} >>>> Target Intron 12 >>>> {s}CysProThrProGlyCysAspGl
{||} 4705 bp {|}|||||||||||||||||||||||
{Ly}++ ++{s}CysProThrProGlyCysAspGl
{AA}gt ag{G}TGCCCCACGCCCGGCTGTGATGG
ySerGlyHisIleThrGlyAsnTyrAlaSerHisArg{Se} >>>> Target Intro
|||||||||||||||||||||||||||||||||||||{||} 416 bp
ySerGlyHisIleThrGlyAsnTyrAlaSerHisArg{Se}++
CTCCGGTCACATAACAGGGAACTACGCTTCGCACCGG{AG}gt
n 13 >>>> {r}LeuSerGlyCysProArgAlaLysLysSerGlyValLysValAlaP
{|}||||||||||||||||||||||||||||||||||||||||||||||
++{r}LeuSerGlyCysProArgAlaLysLysSerGlyValLysValAlaP
ag{C}TTGTCGGGCTGCCCTCGCGCCAAGAAGAGTGGAGTCAAGGTGGCAC
roThrLysAspAspLysGluAspProGluLeuMet{Ly} >>>> Target Intron
|||||||||||||||||||||||||||||||||||{||} 3560 bp
roThrLysAspAspLysGluAspProGluLeuMet{Ly}++
CCACCAAGGACGATAAGGAGGACCCTGAGCTGATG{AA}gt
14 >>>> {s}CysProValProGlyCysValGlyLeuGlyHisIleSerGlyLysTyr
{|}||||||||||||||||||||||||||||||||||||||||||||||||
++{s}CysProValProGlyCysValGlyLeuGlyHisIleSerGlyLysTyr
ag{G}TGCCCAGTTCCAGGCTGCGTGGGGCTCGGTCACATCAGCGGCAAATAC
AlaSerHisArgSerAlaSerGlyCysProLeuAlaAlaArgArgGlnLysGluGlySer
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
AlaSerHisArgSerAlaSerGlyCysProLeuAlaAlaArgArgGlnLysGluGlySer
GCCTCTCACAGGAGTGCGTCCGGCTGCCCACTGGCTGCCCGGAGGCAGAAAGAGGGTTCC
LeuAsnGlySerSerPheSerTrpLysSerLeuLysAsnGluGlyProThrCysProThr
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
LeuAsnGlySerSerPheSerTrpLysSerLeuLysAsnGluGlyProThrCysProThr
CTCAATGGCTCATCGTTCTCCTGGAAGTCGCTGAAGAACGAGGGGCCCACTTGCCCCACC
ProGlyCysAspGlySerGlyHisAlaAsnGlySerPheLeuThrHisArg{Se} >>>
|||||||||||||||||||||||||||||||||||||||||||||||||||{||}
ProGlyCysAspGlySerGlyHisAlaAsnGlySerPheLeuThrHisArg{Se}++
CCAGGCTGCGATGGTTCTGGCCACGCCAACGGGAGCTTCCTCACCCACCGG{AG}gt
> Target Intron 15 >>>> {r}LeuSerGlyCysProArgAlaThrPheAlaGl
1753 bp {|}||||||||||||||||||||||||||||||||
++{r}LeuSerGlyCysProArgAlaThrPheAlaGl
ag{T}CTGTCTGGCTGTCCAAGAGCAACCTTTGCTGG
yLysLysGlyLysLeuSerGlyAspGluValLeuSerProLysPheLysThrSerAsp{V
|||||||||||||||||||||| |||||||||||||||||||||||||||||||||{|
yLysLysGlyLysLeuSerGlyGluGluValLeuSerProLysPheLysThrSerAsp{V
AAAGAAGGGAAAACTCTCAGGGGAGGAGGTTCTCAGTCCAAAGTTCAAGACCAGTGAC{G
} >>>> Target Intron 16 >>>> {al}LeuGluAsnAspGluGluIleLysG
} 771 bp {||}||||||||||||||| |||||||
}++ ++{al}LeuGluAsnAspGluAspIleLysG
}gt ag{TG}CTGGAGAATGACGAGGACATCAAAC
lnLeuAsnGlnGluIleArgAspLeuAsnGluSerAsnSerGluMetGluAlaAlaMetV
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
lnLeuAsnGlnGluIleArgAspLeuAsnGluSerAsnSerGluMetGluAlaAlaMetV
AGCTGAACCAGGAGATTCGAGACCTGAATGAGTCCAACTCGGAGATGGAGGCTGCCATGG
alGlnLeuGlnSerGln >>>> Target Intron 17 >>>> IleSerSerMetG
||||||||||||||||| 2319 bp |||||||||||||
alGlnLeuGlnSerGln++ ++IleSerSerMetG
TGCAGCTGCAGTCCCAGgt agATCTCCTCCATGG
luLysAsnLeuLysAsnIleGluGluGluAsnLysLeuIleGluGluGlnAsnGluAlaL
|||||||||||||| |||||||||||||||||||||||||||||||||||||||||||
luLysAsnLeuLysSerIleGluGluGluAsnLysLeuIleGluGluGlnAsnGluAlaL
AGAAGAATCTCAAGAGCATCGAGGAGGAGAACAAGCTAATCGAGGAGCAGAACGAGGCAC
euPheLeuGluLeuSerGlyLeuSerGlnAlaLeuIleGlnSerLeuAlaAsnIleArgL
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
euPheLeuGluLeuSerGlyLeuSerGlnAlaLeuIleGlnSerLeuAlaAsnIleArgL
TGTTTCTGGAGCTGTCTGGCCTGAGTCAGGCCCTCATCCAAAGTCTCGCCAACATCCGCC
euProHisMet >>>> Target Intron 18 >>>> GluProIleCysGluGlnA
||||||||||| 571 bp |||||||||||||||||||
euProHisMet++ ++GluProIleCysGluGlnA
TTCCGCACATGgt agGAGCCAATATGCGAACAGA
snPheAspAlaTyrValSerThrLeuThrAspMetTyrSerAsn<-><-><-><->GlnA
|||||||||||||||||||||||||||||||||||||||||||| ||||
snPheAspAlaTyrValSerThrLeuThrAspMetTyrSerAsnGlnGluCysTyrGlnA
ATTTCGACGCCTACGTGAGCACCCTCACTGACATGTACTCCAACCAGGAGTGCTACCAGG
spProGluAsnLysAspLeuLeuGluSerIleLysGlnAlaValArgGlyIleGlnVal
|||||||| ||||||||||||||||||||||||||||||||||||||||||||||||
spProGluHisLysAspLeuLeuGluSerIleLysGlnAlaValArgGlyIleGlnVal
ACCCGGAGCACAAGGACCTCTTGGAGAGCATCAAGCAGGCCGTGAGGGGCATCCAGGTC
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