| Basic information |
| Official Symbol | KCNH6 |
| Description | potassium voltage-gated channel, subfamily H (eag-related), member 6 |
| Other Aliases | ERG2, HERG2, Kv11.2 |
| Other Description | ERG-2; eag related protein 2; eag-related gene member 2; eag-related protein 2; ether-a-go-go related gene potassium channel 2; ether-a-go-go-related gene potassium channel 2; ether-a-go-go-related protein 2; hERG-2; potassium voltage-gated channel subfamily H member 6; voltage-gated potassium channel subunit Kv11.2 |
| Mutation type | Insert and frame-shift 772-773:A-G^CG, premature termination 992:W->TAG |
| Location | Scaffold000187_1:5278469 5256451 - |
| Wiki | Wikipedia GeneCard |
| Sequence |
| KCNH6 |
ATGCCGGTCCGGAGGGGCCACGTCGCTCCCCAAAACACTTACCTGGACAC CATCATTCGCAAGTTCGAGGGCCAGAGTCGTAAGTTCCTGATTGCCAATG CTCAGATGGAGAACTGTGCCATCATTTACTGCAATGACGGCTTCTGCGAA CTCTTCGGCTACTCCCGCGTGGAGGTGATGCAGCGCCCCTGCACCTGCGA CTTCCTCACCGGCCCCAACACCCCAAGCAGTGCTGTGTCCCGGCTGGCGC AGGCCCTGCTGGGAGCCGAGGAGTGCAAGGTGGACATCCTCTACTACCGC AAAGATGCCTCCAGCTTCCGCTGCCTGGTGGATGTGGTGCCTGTGAAGAA CGAGGAAGGGGCAGTCATCATGTTCATCCTCAACTTCGAGGACCTGGCCC AGGTCCTGGCCAAGAATGAAGGTCGCAGCCTACCCCAGCGCCTGCTATCC CAGAGCTTCCTGGGCTCCGAGGGCTCCCGTGGCAGGCTGGGCGGGCAGGG CCCTGGCACCAGCAGGGGCAAGTACAAGACCATCAGCCAGATCCCGCAGT TCACTCTCAACTTCGTGGAGTTCAACCTGGAGAAGCACCGCTCGGGCTCC AACACAGAGATTGAGATCATCGCACCCCACAAGGTGGTGGAGCGGACGCA GAATGTCACTGAGAAGGTCACCCAGGTGCTGTCGCTGGGTGCGGACGTGC TGCCGGAGTACAAGCTGCAGGCGCCGCGCATCCACCGCTGGCCCATCCTG CACTACAGCCCCTTCAAGGCCGTGTGGGACTGGCTCATCCTGCTGCTGGT CATCTACACAGCCGTCTTCACGCCCTACTCGGCCGCCTTCCTGCTCAGCC ACCAGGATGAGTCACAGCGTGGCACCTGCGGCTACACCTGCAGTCCACTC ACCGTGGTGGACCTCATTGTGGACATCATGTTTGTCGTGGACATTGTCAT CAACTTCCGTACCACATATGTCAACACCAACGACGAAGTGGTCAGCCACC CCCGCCGCATCGCCGTGCACTACTTCAAGGGCTGGTTCCTCATCGACATG GTGGCTGCCATCCCCTTCGACCTGCTCATCTTCCGCACTGGCTCTGATGA GACCACGACCCTGATTGGGCTACTGAAGACAGCACGGCTGCTACGGCTGG TGCGCGTGGCCCGGAAGCTGGACCGCTACTCTGAGTACGGGGCGGCTGTG CTCTTCCTGCTCATGTGCACCTTCGCACTCATCGCGCACTGGCTGGCCTG CATCTGGTACGCCATCGGCAATGTGGAGCGGCCCTACCTGGAGCCCAAGA TTGGCTGGCTGGACAGCCTGGGCGTGCAGCTCGGCAAGCGCTACAATGGC AGCGACCCAGCCTCAGGCCCCTCGGTGCAGGACAAGTATGTCACGGCCCT GTACTTCACCTTCAGCAGCCTCACCAGCGTGGGCTTCGGCAACGTCTCCC CCAACACCAACTCTGAGAAGGTCTTCTCCATCTGCGTCATGCTCATCGGC TCCCTGATGTACGCCAGTATCTTCGGCAACGTGTCCGCCATCATCCAGCG CCTGTACTCGGGGACCGCGCGCTACCATGCACAGATGCTGCGCATCAAGG AGTTCATCCGCTTCCACCAGATTCCCAACCCGCTGCGACAGCGCCTGGAG GAGTACTTCCAGCACGCCTGGTCCTACACCAACGGCATCGACATGAACGC GGTGCTGAAGGGCTTCCCCGAGTGCCTGCAGGCCGACATCTGCCTGCACC TGCACCGCGCGCTGCTGCAGCACTGTCCAGCCTTTCGCGGCGCCAGCAAG GGCTGCCTGCGCGCGCTCGCTGTCAAGTTCAAGACCACGCACGCGCCGCC GGGGGACACGCTGGTGCACCTGGGCGACGTGCTCTCCACGCTCTACTTCA TTTCCCGCGGCTCCATCGAGATTCTGCGCGACGATGTGGTCGTGGCCATC CTAGGGAAGAACGACATCTTTGGGGAACCAGTTAGCCTCCATGCGCGGCC GGGCAAGTCCAGTGCAGACGTGCGGGCCCTGACCTACTGTGACCTGCACA AGATCCAGCGGGCAGACCTGCTGGAGGTCCTGGACATGTATCCTGCCTTT GCGGACAGCTTCTGGAGTAAGCTGGAGGTCACCTTCAACCTGCGGGACGC AGATGGGGGTCTTCAGTCATCACCCCAACAGGCTCCAGGCAATCAAGACC GCCAGAACTTCTTCCTTGACAACGACCAGGCAGGTCCCCCTTCAAAGCCA AGGACCCAGCTCTCTACCCAGGCTTATGTCCTCCTAGGTCCTGGAAACCA GAACTCCTTAGGGGGACCTTGCGCTCTAGGGCACCCAGGTACAGCACCTT CCCTGGGCATCTCAGATGCATCTGGCCTCTGGCCAGAGTTAATACAGCAA GTGCCTTCAAGGCATAGCCCCCCAAACCCTCAGGGAGACCCAGAACGCTG GCCTCGGGAACTAGGCTCCAGGCTAGAGCGGCTCCAGGCCCAGGTGAACA GGCTGGAGTCCCGCATGTCCTCAGATCTCAGCCGTATCCTGCAGCTCCTT CAGCAGCCCACACCCCCGGGCCACACTAGCTACATCCTAGGAGCCTCTGA CTCCAGCGACCTGGCCTTGTTTCCTGCAGCCTCGGCCACCCAGAGTCCGG GGCCCAGGCTGCCTCAGGGCCTTCTGGCCCCTGCACAGACTCTGAGCTAT GGCGACTTGGACAAGTATATGCCGGAGCACAGGAACTCCTCCAGTCTGCC TCACTTGGCTGTGGCAGTGGACAGAACTCTGACAGCCTCTTCAGAACAGG AGCATCCTGGCAGGCTCCTGACCCCCCTGGCTTTACCTCTGTGTCCCCTT GAGGTGCAGGGACTCATCTGTGGTCCTCGCTTCCCCTCTCTTCCTGAAGA TCTTGACTCTGTCCCCAAGCAGCTGGAGTTCCAGAGACATGGCTCAGACC CAGGATTTGCAGGGAGGTAGGGG |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 994 | 1 | 993 | Insert and frame-shift 772-773:A-G^CG, Premature termination 992:W->TAG |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
MetProValArgArgGlyHisValAlaProGlnAsnThrTyrLeuAspThrIleIleArg
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
MetProValArgArgGlyHisValAlaProGlnAsnThrTyrLeuAspThrIleIleArg
ATGCCGGTCCGGAGGGGCCACGTCGCTCCCCAAAACACTTACCTGGACACCATCATTCGC
LysPheGluGlyGln{S} >>>> Target Intron 1 >>>> {er}ArgLysPhe
|||||||||||||||{|} 756 bp {||}|||||||||
LysPheGluGlyGln{S}++ ++{er}ArgLysPhe
AAGTTCGAGGGCCAG{A}gt ag{GT}CGTAAGTTC
LeuIleAlaAsnAlaGlnMetGluAsnCysAlaIleIleTyrCysAsnAspGlyPheCys
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
LeuIleAlaAsnAlaGlnMetGluAsnCysAlaIleIleTyrCysAsnAspGlyPheCys
CTGATTGCCAATGCTCAGATGGAGAACTGTGCCATCATTTACTGCAATGACGGCTTCTGC
GluLeuPheGlyTyrSerArgValGluValMetGlnGlnProCysThrCysAspPheLeu
|||||||||||||||||||||||||||||||||||| |||||||||||||||||||||
GluLeuPheGlyTyrSerArgValGluValMetGlnArgProCysThrCysAspPheLeu
GAACTCTTCGGCTACTCCCGCGTGGAGGTGATGCAGCGCCCCTGCACCTGCGACTTCCTC
ThrGlyProAsnThrProSerSerAlaValSerArgLeuAlaGlnAlaLeuLeuGlyAla
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ThrGlyProAsnThrProSerSerAlaValSerArgLeuAlaGlnAlaLeuLeuGlyAla
ACCGGCCCCAACACCCCAAGCAGTGCTGTGTCCCGGCTGGCGCAGGCCCTGCTGGGAGCC
GluGluCysLysValAspIleLeuTyrTyrArgLysAsp{A} >>>> Target Intr
|||||||||||||||||||||||||||||||||||||||{|} 4832 bp
GluGluCysLysValAspIleLeuTyrTyrArgLysAsp{A}++
GAGGAGTGCAAGGTGGACATCCTCTACTACCGCAAAGAT{G}gt
on 2 >>>> {la}SerSerPheArgCysLeuValAspValValProValLysAsnGlu
{||}|||||||||||||||||||||||||||||||||||||||||||||
++{la}SerSerPheArgCysLeuValAspValValProValLysAsnGlu
ag{CC}TCCAGCTTCCGCTGCCTGGTGGATGTGGTGCCTGTGAAGAACGAG
AspGlyAlaValIleMetPheIleLeuAsnPheGluAspLeuAlaGlnLeuLeuAlaLys
||||||||||||||||||||||||||||||||||||||||||||| |||||||||
GluGlyAlaValIleMetPheIleLeuAsnPheGluAspLeuAlaGlnValLeuAlaLys
GAAGGGGCAGTCATCATGTTCATCCTCAACTTCGAGGACCTGGCCCAGGTCCTGGCCAAG
CysSerSerArgSerLeuSerGlnArgLeuLeuSerGlnSerPheLeuGlySer{G} >
||||||||| |||||||||||||||||||||||||||||||||{|}
AsnGluGlyArgSerLeuProGlnArgLeuLeuSerGlnSerPheLeuGlySer{G}++
AATGAAGGTCGCAGCCTACCCCAGCGCCTGCTATCCCAGAGCTTCCTGGGCTCC{G}gt
>>> Target Intron 3 >>>> {lu}GlySerHisGlyArgProGlyGlyProGly
85 bp {||}|||||| |||||| |||||| |||
++{lu}GlySerArgGlyArgLeuGlyGlyGlnGly
ag{AG}GGCTCCCGTGGCAGGCTGGGCGGGCAGGGC
ProGlyThrGlyArgGlyLysTyrArgThrIleSerGlnIleProGlnPheThrLeuAsn
||||||||| |||||||||||| |||||||||||||||||||||||||||||||||
ProGlyThrSerArgGlyLysTyrLysThrIleSerGlnIleProGlnPheThrLeuAsn
CCTGGCACCAGCAGGGGCAAGTACAAGACCATCAGCCAGATCCCGCAGTTCACTCTCAAC
PheValGluPheAsnLeuGluLysHisArgSerSerSerThrThrGluIleGluIleIle
||||||||||||||||||||||||||||||||| ||| ||||||||||||||||||
PheValGluPheAsnLeuGluLysHisArgSerGlySerAsnThrGluIleGluIleIle
TTCGTGGAGTTCAACCTGGAGAAGCACCGCTCGGGCTCCAACACAGAGATTGAGATCATC
AlaProHisLysValValGluArgThrGlnAsnValThrGluLysValThrGln >>>>
||||||||||||||||||||||||||||||||||||||||||||||||||||||
AlaProHisLysValValGluArgThrGlnAsnValThrGluLysValThrGln++
GCACCCCACAAGGTGGTGGAGCGGACGCAGAATGTCACTGAGAAGGTCACCCAGgt
Target Intron 4 >>>> ValLeuSerLeuGlyAlaAspValLeuProGluTyrL
3641 bp |||||||||||||||||||||||||||||||||||||
++ValLeuSerLeuGlyAlaAspValLeuProGluTyrL
agGTGCTGTCGCTGGGTGCGGACGTGCTGCCGGAGTACA
ysLeuGlnAlaProArgIleHisArgTrpThrIleLeuHisTyrSerProPheLysAlaV
||||||||||||||||||||||||||||| ||||||||||||||||||||||||||||
ysLeuGlnAlaProArgIleHisArgTrpProIleLeuHisTyrSerProPheLysAlaV
AGCTGCAGGCGCCGCGCATCCACCGCTGGCCCATCCTGCACTACAGCCCCTTCAAGGCCG
alTrpAspTrpLeuIleLeuLeuLeuValIleTyrThrAlaValPheThrProTyrSerA
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
alTrpAspTrpLeuIleLeuLeuLeuValIleTyrThrAlaValPheThrProTyrSerA
TGTGGGACTGGCTCATCCTGCTGCTGGTCATCTACACAGCCGTCTTCACGCCCTACTCGG
laAlaPheLeuLeuSerAspGlnAspGluSerArgArgGlyAlaCysSerTyrThrCysS
||||||||||||||||| |||||||||||| |||||| ||| ||||||||||
laAlaPheLeuLeuSerHisGlnAspGluSerGlnArgGlyThrCysGlyTyrThrCysS
CCGCCTTCCTGCTCAGCCACCAGGATGAGTCACAGCGTGGCACCTGCGGCTACACCTGCA
erProLeuThrValValAspLeuIleValAspIleMetPheValValAspIleValIleA
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
erProLeuThrValValAspLeuIleValAspIleMetPheValValAspIleValIleA
GTCCACTCACCGTGGTGGACCTCATTGTGGACATCATGTTTGTCGTGGACATTGTCATCA
snPheArgThrThrTyrValAsnThrAsnAspGluValValSerHisProArgArgIleA
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
snPheArgThrThrTyrValAsnThrAsnAspGluValValSerHisProArgArgIleA
ACTTCCGTACCACATATGTCAACACCAACGACGAAGTGGTCAGCCACCCCCGCCGCATCG
laValHisTyrPheLysGlyTrpPheLeuIleAspMetValAlaAlaIleProPheAspL
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
laValHisTyrPheLysGlyTrpPheLeuIleAspMetValAlaAlaIleProPheAspL
CCGTGCACTACTTCAAGGGCTGGTTCCTCATCGACATGGTGGCTGCCATCCCCTTCGACC
euLeuIlePheArgThrGlySerAspGlu >>>> Target Intron 5 >>>> Th
||||||||||||||||||||||||||||| 1358 bp ||
euLeuIlePheArgThrGlySerAspGlu++ ++Th
TGCTCATCTTCCGCACTGGCTCTGATGAGgt agAC
rThrThrLeuIleGlyLeuLeuLysThrAlaArgLeuLeuArgLeuValArgValAlaAr
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
rThrThrLeuIleGlyLeuLeuLysThrAlaArgLeuLeuArgLeuValArgValAlaAr
CACGACCCTGATTGGGCTACTGAAGACAGCACGGCTGCTACGGCTGGTGCGCGTGGCCCG
gLysLeuAspArgTyrSerGluTyrGlyAlaAlaValLeuPheLeuLeuMetCysThrPh
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
gLysLeuAspArgTyrSerGluTyrGlyAlaAlaValLeuPheLeuLeuMetCysThrPh
GAAGCTGGACCGCTACTCTGAGTACGGGGCGGCTGTGCTCTTCCTGCTCATGTGCACCTT
eAlaLeuIleAlaHisTrpLeuAlaCysIleTrpTyrAlaIleGlyAsnValGluArgPr
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
eAlaLeuIleAlaHisTrpLeuAlaCysIleTrpTyrAlaIleGlyAsnValGluArgPr
CGCACTCATCGCGCACTGGCTGGCCTGCATCTGGTACGCCATCGGCAATGTGGAGCGGCC
oTyrLeuGluHisLysIleGlyTrpLeuAspSerLeuGlyValGlnLeuGlyLysArgTy
|||||||||| |||||||||||||||||||||||||||||||||||||||||||||||
oTyrLeuGluProLysIleGlyTrpLeuAspSerLeuGlyValGlnLeuGlyLysArgTy
CTACCTGGAGCCCAAGATTGGCTGGCTGGACAGCCTGGGCGTGCAGCTCGGCAAGCGCTA
rAsnGlySerAspProAlaSerGlyProSerValGlnAspLysTyrValThrAlaLeuTy
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
rAsnGlySerAspProAlaSerGlyProSerValGlnAspLysTyrValThrAlaLeuTy
CAATGGCAGCGACCCAGCCTCAGGCCCCTCGGTGCAGGACAAGTATGTCACGGCCCTGTA
rPheThrPheSerSerLeuThrSerValGlyPheGlyAsnValSerProAsnThrAsnSe
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
rPheThrPheSerSerLeuThrSerValGlyPheGlyAsnValSerProAsnThrAsnSe
CTTCACCTTCAGCAGCCTCACCAGCGTGGGCTTCGGCAACGTCTCCCCCAACACCAACTC
rGluLysValPheSerIleCysValMetLeuIleGly{S} >>>> Target Intron
|||||||||||||||||||||||||||||||||||||{|} 1905 bp
rGluLysValPheSerIleCysValMetLeuIleGly{S}++
TGAGAAGGTCTTCTCCATCTGCGTCATGCTCATCGGC{T}gt
6 >>>> {er}LeuMetTyrAlaSerIlePheGlyAsnValSerAlaIleIleGlnAr
{||}|||||||||||||||||||||||||||||||||||||||||||||||
++{er}LeuMetTyrAlaSerIlePheGlyAsnValSerAlaIleIleGlnAr
ag{CC}CTGATGTACGCCAGTATCTTCGGCAACGTGTCCGCCATCATCCAGCG
gLeuTyrSerGlyThrAlaArgTyrHisThrGlnMetLeuArgValLysGluPheIleAr
|||||||||||||||||||||||||||| |||||||||||| ||||||||||||||
gLeuTyrSerGlyThrAlaArgTyrHisAlaGlnMetLeuArgIleLysGluPheIleAr
CCTGTACTCGGGGACCGCGCGCTACCATGCACAGATGCTGCGCATCAAGGAGTTCATCCG
gPheHisGlnIleProAsnProLeuArgGlnArgLeuGluGluTyrPheGlnHisAlaTr
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
gPheHisGlnIleProAsnProLeuArgGlnArgLeuGluGluTyrPheGlnHisAlaTr
CTTCCACCAGATTCCCAACCCGCTGCGACAGCGCCTGGAGGAGTACTTCCAGCACGCCTG
pSerTyrThrAsnGlyIleAspMetAsnAla >>>> Target Intron 7 >>>>
||||||||||||||||||||||||||||||| 137 bp
pSerTyrThrAsnGlyIleAspMetAsnAla++ ++
GTCCTACACCAACGGCATCGACATGAACGCGgt ag
ValLeuLysGlyPheProGluCysLeuGlnAlaAspIleCysLeuHisLeuHisArgAla
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ValLeuLysGlyPheProGluCysLeuGlnAlaAspIleCysLeuHisLeuHisArgAla
GTGCTGAAGGGCTTCCCCGAGTGCCTGCAGGCCGACATCTGCCTGCACCTGCACCGCGCG
LeuLeuGlnHisCysProAlaPheSerGlyAlaGlyLysGlyCysLeuArgAlaLeuAla
|||||||||||||||||||||||| |||||| ||||||||||||||||||||||||
LeuLeuGlnHisCysProAlaPheArgGlyAlaSerLysGlyCysLeuArgAlaLeuAla
CTGCTGCAGCACTGTCCAGCCTTTCGCGGCGCCAGCAAGGGCTGCCTGCGCGCGCTCGCT
ValLysPheLysThrThrHisAlaProProGlyAspThrLeuValHisLeuGlyAspVal
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ValLysPheLysThrThrHisAlaProProGlyAspThrLeuValHisLeuGlyAspVal
GTCAAGTTCAAGACCACGCACGCGCCGCCGGGGGACACGCTGGTGCACCTGGGCGACGTG
LeuSerThrLeuTyrPheIleSerArgGlySerIleGluIleLeuArgAspAspValVal
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
LeuSerThrLeuTyrPheIleSerArgGlySerIleGluIleLeuArgAspAspValVal
CTCTCCACGCTCTACTTCATTTCCCGCGGCTCCATCGAGATTCTGCGCGACGATGTGGTC
ValAlaIleLeu{G} >>>> Target Intron 8 >>>> {ly}LysAsnAspIle
||||||||||||{|} 3277 bp {||}||||||||||||
ValAlaIleLeu{G}++ ++{ly}LysAsnAspIle
GTGGCCATCCTA{G}gt ag{GG}AAGAACGACATC
PheGlyGluProValSerLeuHisAlaGlnProGlyLysSerSerAlaAspValArgAla
||||||||||||||||||||||||||| ||||||||||||||||||||||||||||||
PheGlyGluProValSerLeuHisAlaArgProGlyLysSerSerAlaAspValArgAla
TTTGGGGAACCAGTTAGCCTCCATGCGCGGCCGGGCAAGTCCAGTGCAGACGTGCGGGCC
LeuThrTyrCysAspLeuHisLysIleGlnArgAlaAspLeuLeuGluValLeuAspMet
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
LeuThrTyrCysAspLeuHisLysIleGlnArgAlaAspLeuLeuGluValLeuAspMet
CTGACCTACTGTGACCTGCACAAGATCCAGCGGGCAGACCTGCTGGAGGTCCTGGACATG
TyrProAlaPheAlaGluSerPheTrpSerLysLeuGluValThrPheAsnLeuArgAsp
||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
TyrProAlaPheAlaAspSerPheTrpSerLysLeuGluValThrPheAsnLeuArgAsp
TATCCTGCCTTTGCGGACAGCTTCTGGAGTAAGCTGGAGGTCACCTTCAACCTGCGGGAC
>>>> Target Intron 9 >>>> AlaAlaGlyGlyLeuHisSerSerProArgG
1460 bp ||| ||||||||| ||||||||| |
++ ++AlaAspGlyGlyLeuGlnSerSerProGlnG
gt agGCAGATGGGGGTCTTCAGTCATCACCCCAAC
lnAlaProGlySerGlnAspHisGlnGlyPhePheLeuSerAspAsnGlnSerGly >>
||||||||||| |||||| ||| ||||||||| ||| |||
lnAlaProGlyAsnGlnAspArgGlnAsnPhePheLeuAspAsnAspGlnAlaGly+-
AGGCTCCAGGCAATCAAGACCGCCAGAACTTCTTCCTTGACAACGACCAGGCAGGTgg
>> Target Intron 10 >>>> SerProHisGluLeuGlyProGlnPheProSerL
291 bp ||| |||
++ProProSerLysProArgThrGlnLeuSerThrG
agCCCCCTTCAAAGCCAAGGACCCAGCTCTCTACCC
ysGlyTyrSerLeuLeuGlyProGlySerGlnAsnSerMetGlyAla--GlyProCysAl
||| ||||||||||||||| ||||||||| ||| ##|||||||||||
lnAlaTyrValLeuLeuGlyProGlyAsnGlnAsnSerLeuGly---##GlyProCysAl
AGGCTTATGTCCTCCTAGGTCCTGGAAACCAGAACTCCTTAGGG---CGGGACCTTGCGC
aProGlyHisPro{A} >>>> Target Intron 11 >>>> {sp}AlaAlaProP
| |||||||||{ } 126 bp { } ||||||
aLeuGlyHisPro{G}++ ++{ly}ThrAlaProS
TCTAGGGCACCCA{G}gt ag{GT}ACAGCACCTT
roLeuSerIleSerAspAlaSerGlyLeuTrpProGluLeuLeuGlnGluMetProProA
||| ||||||||||||||||||||||||||||||||| ||| ||| |
erLeuGlyIleSerAspAlaSerGlyLeuTrpProGluLeuIleGlnGlnValProSerA
CCCTGGGCATCTCAGATGCATCTGGCCTCTGGCCAGAGTTAATACAGCAAGTGCCTTCAA
rgHisSerProGlnSerProGlnGluAspProAspCysTrpProLeuLysLeuGlySerA
||||||||||| |||||| |||||| |||||| ||||||||||
rgHisSerProProAsnProGlnGlyAspProGluArgTrpProArgGluLeuGlySerA
GGCATAGCCCCCCAAACCCTCAGGGAGACCCAGAACGCTGGCCTCGGGAACTAGGCTCCA
rgLeuGluGlnLeuGlnAlaGlnMetAsn{Ar} >>>> Target Intron 12 >>>
|||||||| |||||||||||| |||{||} 895 bp
rgLeuGluArgLeuGlnAlaGlnValAsn{Ar}++
GGCTAGAGCGGCTCCAGGCCCAGGTGAAC{AG}gt
> {g}LeuGluSerArgValSerSerAspLeuSerArgIleLeuGlnLeuLeuGlnLys
{|}|||||||||||| ||||||||||||||||||||||||||||||||||||
++{g}LeuGluSerArgMetSerSerAspLeuSerArgIleLeuGlnLeuLeuGlnGln
ag{G}CTGGAGTCCCGCATGTCCTCAGATCTCAGCCGTATCCTGCAGCTCCTTCAGCAG
ProMetProGlnGlyHisAlaSerTyrIleLeuGluAlaProAlaSerAsnAspLeuAla
||| ||| |||||| |||||||||||| ||| ||| |||||||||
ProThrProProGlyHisThrSerTyrIleLeuGlyAlaSerAspSerSerAspLeuAla
CCCACACCCCCGGGCCACACTAGCTACATCCTAGGAGCCTCTGACTCCAGCGACCTGGCC
LeuValProIleAlaSerGluThrThrSerProGlyProArgLeuProGlnGlyPheLeu
||| ||| |||||| ||| ||||||||||||||||||||||||||| |||
LeuPheProAlaAlaSerAlaThrGlnSerProGlyProArgLeuProGlnGlyLeuLeu
TTGTTTCCTGCAGCCTCGGCCACCCAGAGTCCGGGGCCCAGGCTGCCTCAGGGCCTTCTG
ProProAlaGln >>>> Target Intron 13 >>>> ThrProSerTyrGlyAsp
||||||||| 281 bp ||| ||||||||||||
AlaProAlaGln++ ++ThrLeuSerTyrGlyAsp
GCCCCTGCACAGgt agACTCTGAGCTATGGCGAC
LeuAspAspCysSerProLysHisArgAsnSerSerProArgMetProHisLeuAlaVal
|||||| ||| ||||||||||||||| |||||||||||||||
LeuAspLysTyrMetProGluHisArgAsnSerSer---SerLeuProHisLeuAlaVal
TTGGACAAGTATATGCCGGAGCACAGGAACTCCTCC---AGTCTGCCTCACTTGGCTGTG
AlaThrAspLysThrLeuAlaProSerSerGluGlnGluGlnProGluGlyLeuTrpPro
||| ||| |||||| ||||||||||||||| ||| |||
AlaValAspArgThrLeuThrAlaSerSerGluGlnGluHisProGlyArgLeuLeuThr
GCAGTGGACAGAACTCTGACAGCCTCTTCAGAACAGGAGCATCCTGGCAGGCTCCTGACC
ProLeuAlaSerProLeuHisProLeuGluValGlnGlyLeuIleCysGlyProCysPhe
||||||||| |||||| ||||||||||||||||||||||||||||||||| |||
ProLeuAlaLeuProLeuCysProLeuGluValGlnGlyLeuIleCysGlyProArgPhe
CCCCTGGCTTTACCTCTGTGTCCCCTTGAGGTGCAGGGACTCATCTGTGGTCCTCGCTTC
SerSerLeuProGluHisLeuGlySerValProLysGlnLeuAspPheGlnArgHisGly
|||||||||||| ||| |||||||||||||||||| |||||||||||||||
ProSerLeuProGluAspLeuAspSerValProLysGlnLeuGluPheGlnArgHisGly
CCCTCTCTTCCTGAAGATCTTGACTCTGTCCCCAAGCAGCTGGAGTTCCAGAGACATGGC
SerAspProGlyPheAlaGlySerTrpGly
||||||||||||||||||||| |||
SerAspProGlyPheAlaGlyArg***Gly
TCAGACCCAGGATTTGCAGGGAGGTAGGGG
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