| Basic information |
| Official Symbol | INTS1 |
| Description | integrator complex subunit 1 |
| Other Aliases | UNQ1821/PRO3434, INT1, NET28 |
| Other Description | NA |
| Mutation type | Insert and frame-shift 1152-1153:L-P^C |
| Location | Scaffold145208_1:2164816 2186877 + |
| Wiki | Wikipedia GeneCard |
| Sequence |
| INTS1 |
GGAGCTGCGAGAGGCAGAGGCAGGATGAACAGGGCCAAGCCCACCACCGT CCGGCGGCCCAGCGCTGCGGCCAAACCTTCAGGGCATCCCCCACCAGGAG ACTTCATTGCTCTGGGCTCAAAGAGTCAGGCCAGTGAGTCAAAAACAGCG TCCACTCTGCTGAAGCCAGCCCCGTCTGGCCTGCCTTCGGAGCGCAAGCG GGATGCTACGGCTGCTTTGTCTGGCTCTTCGGCTCTGACTGGTCTCACCA AACGCCCCAAACTCTCCTCCACACCACCTCTGAGTGCCCTGGGACGCCTG GCTGAAGCTGCAGTGGCAGAAAAACGAGCCATTTCTCCCTCAATTAAAGA ACCATCCGTGGTGCCAATCGAAGTTCTCCCCACAGTACTGCTGGATGAGA TAGAAGCCGCTGAGCTAGAGGGCAATGATGACAGGATTGAGGGAGTGCTG TGCGGGGCGGTGAAGCAGCTGAAGGTCACCCGGGCCAAGCCAGACGGCAC TCTGTACCTGAGCCTCATGTACCTGGCCAAGATCAAGCCCAACATCTTTG CCACAGAGGGTGTCATTGAGGCTCTTTGCAGCCTCCTGCGGAGGGATGCC TCCATCAACTTCAAGGCCAAGGGGAACAGTCTGGTGTCCGTGCTGGCCTG TAATCTTCTCATGGCCGCGTACGAGGAGGACGAGAACTGGCCCGAGATCT TTGTCAAGGTATACATCGAGGACTCCCTAGGGGAGCGGATCTGGGTGGAC AGCCCTCACTGCAAGACATTTGTGGACAACATCCAGACGGCGTTTAACAC CAAGATGCCCCCCAAGAGCATGCTGCTGCAGGGGGAGGTGGGGCGCAGTG GGGGGGACCTCGGTGCTGGGAGCAGCCCTCACCCCTCCCTCACAGAGGAG GAGGACAGCCAGACAGAGCTGCTGATCGCGGAGGAGAAGCTGAGCCCCGA GCAGGAGGGCCAGCTCATGCCCAGGTACGATGACCTCACAGAGAGTGTGG AGGAATATGTTCTAGACATGCTCCGGGACCAGCTCAACCGGCGCCAGCCC ATTGACAATGTCTCGAGGAACCTCCTGCGGCTTCTCACCTCCACCTGTGG CTATAAGGAGGTGCGGCTGATGGCAGTGCAGAAGTTGGAGATGTGGCTAC AGAACCCCAAGCTGACTAGGCCAGCCCAAGACCTGCTCATGTCCGTGTGC ATGAATTGCAACACGCACGGCTCGGAGGACATGGATGTCATTTCTCACCT GATCAAGATCCGCCTCAAGCCCAAGGTTCTCCTGAACCACTACATGCTGT GTGTCAGGGAGCTGCTGAGCGCTCACAAGGACAACTTGGGCACAACCATT AAGTTTGTGATCTTCAATGAACTTTCCAATGCCCGGAACCCAAACAACAT GCAGATCCTCTACACTGTGCTGCAGCACAGCTCGGAGCTGGCACCCAAGT TCCTGGCCATGGTGTTCCAGGACCTCCTGACCAACAAGGATGACTACCTG CGAGCCTCACGGGCCCTGCTCCGGGAAATCATCAAGCAGACCAAGCACGA GATCAATTTCCAGGCCTTCTGCCTCGGGCTCATGCAGGAGCGCAAAGAGC CCCAGTACCTGGACATGGAGTTCAAGGAGCGGTTTGTGGTCCACATTACA GACGTGCTGGCCGTGTCCATGATGCTGGGCATCACGGCTCAGGTGAAGGA GGCTGGTGTTGCCTGGGACAAAGGAGAAAAGAGGAATCTCGAAGTGCTGC GCTCGTTCCAGAACCAGATCGCTGCGATCCAGCGGGATGCTGTTTGGTGG CTTCACACAGTGGTCCCTTCCATCAGCAAACTCGCCCCCAAGGACTACGT GCACTGCCTCCACAAGGTGCTCTTCACAGAGCAGCCGGAGACCTACTACA AGTGGGACAACTGGCCTCCTGAGAGTGACCGCAACTTCTTCCTGCGCCTC TGCTCAGAGGTCCCCATTCTGGAGGACACACTGATGCGCATCCTAGTCAT CGGACTGTCTCGGGAGCTCCCGCTCGGCCCTGCAGACGCCATGGAGCTCG CTGACCACCTGGTGAAGCGTGCTGCAGCCGTGCAGGCGGATGATGTGGAA GTGCTCAAGGTGGAGAGAATCCAGTTGATCGATGCTGTACTGAACCTGTG CACCTACCATCATCCGGAGAACATCCAGCTCCCACCTGGATACCAGCCTC CGAACCTGGCCATCTCGACCCTCTACTGGAAGGCCTGGCCCCTCCTGCTG GTGGTCGCCGCGTTCAACCCCGAGAACATCGGCCTGGCTGCCTGGGAGGA GTACCCCACCCTGAAGATGCTCATGGAAATGGTAATGACCAATAACTACT CCTACCCCCCGTGCACCCTGACGGATGAGGAAACCCGGACAGAGATGATT AATCGAGAGTTGCAGATCTCCCAGCGAGAGAAGCAGGAAATCCTGGCATT TGAGGGACATCTGGCTGCTGCATCCACGAAGCAGACTATCACTGAGAGCA GCAGCCTCCTTCTGTCTCAGCTCACCAGCCTGGACCCCCAGTATGCACTG CATCCCTGCCCCCACCCCTGCCCCAGAAATGTAGGGCCCCCCCGGAGGCC TCCCCCTCACATCCTAGATCAGGTAAAAGGCCTCAACCAGTCCCTCCGCC TTGGACACCTCCTGTGTCGCAGTCGCAACCCTGACTTCCTCCTCAACATC ATCCAGAGGCAGGCCTCCTCACAGTCCATGCCCTGGCTGGCGGACCTGGT GCAGTCCAGCGAGGGCTCCCTGGACGTGCTGCCCGTGCAGTGCCTGTGCG AGTTCCTGCTGCACGATGCTGCTGACGATGCCACCTCCGGGGAGGAGGAG GATGAGGGCGAGAGCAGAGAGCAGAAGGCCAAGAAGCGGCAGAGGCAGCA GAAGCAGCGGCAGCTGTTGGGCCGCCTGCAGGACCTGCTACTGGGCCCAA AGGCTGACGAGCAGACCACGTGCGAGGTGCTTGACTACTTCCTGCGGCGC CTGGGCTCCTCCCAGGTGGCCTCCCGGGTGCTGGCCATGAAGGTGAGGGG CCTGCCGCTTGTCTCCGTGTCGGGCCCAGCTCTGTGCTGTCTGTTGCAGG GCTTGTCACTGGTGCTTTCGGAGGGCAGCCTACGGGATGGGGAAGAGAAA GAACCCCCCCTGGAAGAGGATTCAGGGGATGCCGACATGCTGCAGGGCTA CCAGTGGCTGCTGAGGGATCTGCCCAGGCTGCCTCTGTTTGACAGCGTGA GGACCACCACCGCCCTGGCACTGCAGCAGGCCATCCACATGGAGACCGAC CCACAGACCATCAGCGCCTACCTGGTCTACCTGTCCCAGCACACACCTGT GGAGGAACAAGGCCAGCACAGCGACCTGGCCCTGGATGTGGCTCGGCTCG TTGTGGAGCGTTCCACCATCATGTCACACCTCTTCTCGAAGCTGTCCTGC AGTGCTGCTTCAGATGCTGTGCTAGGTGCCCTGCTGTCCATCTTTTCCCG CTATGTGAGGCGCATGCGCAAGAGCAAGGAGGGGGAAGAAGTCTACAGCT GGTCGGAGTCTCAGGACCAGGTCTTCCTGCGCTGGACAAGTGGGGAGACC GCAACCATGCACATCCTCGTGGTGCACGCCATGGTCATCCTCCTTACACT GGGCCCACCCCGAGCTGGTGATGGCGAGTTCCATGCGTTGTTGGACATCT GGTTTCCGGAGAAGAAACCCCTGCCCACTGCCTTCCTGGTGGACACGTCT GAGGAGGCGCTGCTGCTGCCCGACTGGTTGAAGTTGCGCATGATTCGCTC AGAGGTCCCACGCCTGGTGGATGCTGCCCTGCAGGACCTGGAGCCCCAAC AGCTGCTGCTCTTCGTGCAGTCCTTTGGCATCCCCGTGTCCAGCATGAGC AAGCTTCTCCAGTACCTAGACCAGGCTGTGGCCCATGACCCCCAGACCCT GGAGCAGAACATCATGGATAAGAGTAAG |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 2394 | 121 | 1447 | Insert and frame-shift 1152-1153:L-P^C |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
GlySerArgGluGlyArgGlyArgMetAsnArgAlaLysProThrThrValArgArgPro
||| ||||||||||||||||||||||||||||||||||||||||||||||||
GlyAlaAlaArgGlyArgGlyArgMetAsnArgAlaLysProThrThrValArgArgPro
GGAGCTGCGAGAGGCAGAGGCAGGATGAACAGGGCCAAGCCCACCACCGTCCGGCGGCCC
SerAlaAlaAlaLysProSer{G} >>>> Target Intron 1 >>>> {ly}His
|||||||||||||||||||||{|} 888 bp {||}|||
SerAlaAlaAlaLysProSer{G}++ ++{ly}His
AGCGCTGCGGCCAAACCTTCA{G}gt ag{GG}CAT
ProProProGlyAspPheIleAlaLeuGlySerLysGlyGlnAlaAsnGluSerLysThr
|||||||||||||||||||||||||||||||||||| |||||| ||||||||||||
ProProProGlyAspPheIleAlaLeuGlySerLysSerGlnAlaSerGluSerLysThr
CCCCCACCAGGAGACTTCATTGCTCTGGGCTCAAAGAGTCAGGCCAGTGAGTCAAAAACA
AlaSerThrLeuLeuLysProAlaProSerGlyLeuProSerGluArgLysArgAspAla
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
AlaSerThrLeuLeuLysProAlaProSerGlyLeuProSerGluArgLysArgAspAla
GCGTCCACTCTGCTGAAGCCAGCCCCGTCTGGCCTGCCTTCGGAGCGCAAGCGGGATGCT
AlaAlaAlaLeuSerSerAlaSerAlaLeuThrGlyLeuThrLysArgProLysLeuSer
|||||||||||| |||||||||||||||||||||||||||||||||||||||
ThrAlaAlaLeuSerGlySerSerAlaLeuThrGlyLeuThrLysArgProLysLeuSer
ACGGCTGCTTTGTCTGGCTCTTCGGCTCTGACTGGTCTCACCAAACGCCCCAAACTCTCC
SerThrProProLeuSerAlaLeuGlyArgLeuAlaGluAlaAlaValAlaGluLysArg
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
SerThrProProLeuSerAlaLeuGlyArgLeuAlaGluAlaAlaValAlaGluLysArg
TCCACACCACCTCTGAGTGCCCTGGGACGCCTGGCTGAAGCTGCAGTGGCAGAAAAACGA
AlaIleSerProSerIleLysGluProSerValValProIleGlu{V} >>>> Targe
|||||||||||||||||||||||||||||||||||||||||||||{|}
AlaIleSerProSerIleLysGluProSerValValProIleGlu{V}++
GCCATTTCTCCCTCAATTAAAGAACCATCCGTGGTGCCAATCGAA{G}gt
t Intron 2 >>>> {al}LeuProThrValLeuLeuAspGluIleGluAlaAlaGlu
701 bp {||}|||||||||||||||||||||||||||||||||||||||
++{al}LeuProThrValLeuLeuAspGluIleGluAlaAlaGlu
ag{TT}CTCCCCACAGTACTGCTGGATGAGATAGAAGCCGCTGAG
LeuGluGlyAsnAspAspArgIleGluGlyValLeuCysGlyAlaValLysGlnLeuLys
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
LeuGluGlyAsnAspAspArgIleGluGlyValLeuCysGlyAlaValLysGlnLeuLys
CTAGAGGGCAATGATGACAGGATTGAGGGAGTGCTGTGCGGGGCGGTGAAGCAGCTGAAG
ValThrArgAlaLysProAspSerThrLeuTyrLeuSerLeuMetTyrLeuAlaLysIle
||||||||||||||||||||| ||||||||||||||||||||||||||||||||||||
ValThrArgAlaLysProAspGlyThrLeuTyrLeuSerLeuMetTyrLeuAlaLysIle
GTCACCCGGGCCAAGCCAGACGGCACTCTGTACCTGAGCCTCATGTACCTGGCCAAGATC
LysProAsnIlePheAlaThrGluGlyValIleGlu >>>> Target Intron 3 >
|||||||||||||||||||||||||||||||||||| 140 bp
LysProAsnIlePheAlaThrGluGlyValIleGlu++
AAGCCCAACATCTTTGCCACAGAGGGTGTCATTGAGgt
>>> AlaLeuCysSerLeuLeuArgArgAspAlaSerIleAsnPheLysAlaLysGlyA
|||||||||||||||||||||||||||||||||||||||||||||||||||||||
++AlaLeuCysSerLeuLeuArgArgAspAlaSerIleAsnPheLysAlaLysGlyA
agGCTCTTTGCAGCCTCCTGCGGAGGGATGCCTCCATCAACTTCAAGGCCAAGGGGA
snSerLeuValSerValLeuAlaCysAsnLeuLeuMetAlaAlaTyrGluGluAspGluA
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
snSerLeuValSerValLeuAlaCysAsnLeuLeuMetAlaAlaTyrGluGluAspGluA
ACAGTCTGGTGTCCGTGCTGGCCTGTAATCTTCTCATGGCCGCGTACGAGGAGGACGAGA
snTrpProGluIlePheValLys >>>> Target Intron 4 >>>> ValTyrIl
||||||||||||||||||||||| 305 bp ||||||||
snTrpProGluIlePheValLys+- ++ValTyrIl
ACTGGCCCGAGATCTTTGTCAAGgc agGTATACAT
eGluAspSerLeuGlyGluArgIleTrpValAspSerProHisCysLysThrPheValAs
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
eGluAspSerLeuGlyGluArgIleTrpValAspSerProHisCysLysThrPheValAs
CGAGGACTCCCTAGGGGAGCGGATCTGGGTGGACAGCCCTCACTGCAAGACATTTGTGGA
pAsnIleGlnThrAlaPheAsnThrArgMetProProArgSerValLeuLeuGlnGlyGl
||||||||||||||||||||||||| ||||||||| ||| ||||||||||||||
pAsnIleGlnThrAlaPheAsnThrLysMetProProLysSerMetLeuLeuGlnGlyGl
CAACATCCAGACGGCGTTTAACACCAAGATGCCCCCCAAGAGCATGCTGCTGCAGGGGGA
uAlaGlyArgValAlaGlyAspLeuGlyAla{G} >>>> Target Intron 5 >>>
| |||||| |||||||||||||||{|} 100 bp
uValGlyArgSerGlyGlyAspLeuGlyAla{G}++
GGTGGGGCGCAGTGGGGGGGACCTCGGTGCT{G}gt
> {ly}SerSerProHisProSerLeuThrGluGluGluAspSerGlnThrGluLeuLe
{||}|||||||||||||||||||||||||||||||||||||||||||||||||||||
++{ly}SerSerProHisProSerLeuThrGluGluGluAspSerGlnThrGluLeuLe
ag{GG}AGCAGCCCTCACCCCTCCCTCACAGAGGAGGAGGACAGCCAGACAGAGCTGCT
uIleAlaGluGluLysLeuSerProGluGlnGluGlyGlnLeuMetPro{Ar} >>>>
|||||||||||||||||||||||||||||||||||||||||||||||||{||}
uIleAlaGluGluLysLeuSerProGluGlnGluGlyGlnLeuMetPro{Ar}++
GATCGCGGAGGAGAAGCTGAGCCCCGAGCAGGAGGGCCAGCTCATGCCC{AG}gt
Target Intron 6 >>>> {g}TyrGluGluLeuAlaGluSerValGluGluTyrVa
110 bp {|}||| ||| ||||||||||||||||||||
++{g}TyrAspAspLeuThrGluSerValGluGluTyrVa
ag{G}TACGATGACCTCACAGAGAGTGTGGAGGAATATGT
lLeuAspMetLeuArgAspGlnLeuAsnArgArgGlnProIleAspAsnValSerArgAs
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
lLeuAspMetLeuArgAspGlnLeuAsnArgArgGlnProIleAspAsnValSerArgAs
TCTAGACATGCTCCGGGACCAGCTCAACCGGCGCCAGCCCATTGACAATGTCTCGAGGAA
nLeuLeuArgLeuLeuThrSerThrCysGlyTyrLysGluValArgLeuLeuAlaValGl
||||||||||||||||||||||||||||||||||||||||||||||||| ||||||||
nLeuLeuArgLeuLeuThrSerThrCysGlyTyrLysGluValArgLeuMetAlaValGl
CCTCCTGCGGCTTCTCACCTCCACCTGTGGCTATAAGGAGGTGCGGCTGATGGCAGTGCA
nLysLeuGluMetTrpLeuGlnAsnProLys >>>> Target Intron 7 >>>>
||||||||||||||||||||||||||||||| 94 bp
nLysLeuGluMetTrpLeuGlnAsnProLys++ ++
GAAGTTGGAGATGTGGCTACAGAACCCCAAGgt ag
LeuThrArgProAlaGlnAspLeuLeuMetSerValCysMetAsnCysAsnThrHisGly
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
LeuThrArgProAlaGlnAspLeuLeuMetSerValCysMetAsnCysAsnThrHisGly
CTGACTAGGCCAGCCCAAGACCTGCTCATGTCCGTGTGCATGAATTGCAACACGCACGGC
SerGluAspMetAspValIleSerHisLeuIleLysIleArgLeuLysProLysValLeu
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
SerGluAspMetAspValIleSerHisLeuIleLysIleArgLeuLysProLysValLeu
TCGGAGGACATGGATGTCATTTCTCACCTGATCAAGATCCGCCTCAAGCCCAAGGTTCTC
LeuAsnHisPheMetLeuCysIle{Ar} >>>> Target Intron 8 >>>> {g}
||||||||| ||||||||| {||} 411 bp {|}
LeuAsnHisTyrMetLeuCysVal{Ar}++ ++{g}
CTGAACCACTACATGCTGTGTGTC{AG}gt ag{G}
GluLeuLeuSerAlaHisLysAspAsnLeuGlyThrThrIleLysLeuValIlePheAsn
||||||||||||||||||||||||||||||||||||||||||||| ||||||||||||
GluLeuLeuSerAlaHisLysAspAsnLeuGlyThrThrIleLysPheValIlePheAsn
GAGCTGCTGAGCGCTCACAAGGACAACTTGGGCACAACCATTAAGTTTGTGATCTTCAAT
GluLeuSerSerAlaArgAsnProAsnAsnMetGlnValLeuTyrThrAlaLeuGlnHis
||||||||| |||||||||||||||||||||||| ||||||||| |||||||||
GluLeuSerAsnAlaArgAsnProAsnAsnMetGlnIleLeuTyrThrValLeuGlnHis
GAACTTTCCAATGCCCGGAACCCAAACAACATGCAGATCCTCTACACTGTGCTGCAGCAC
SerSerGluLeuAlaProLys >>>> Target Intron 9 >>>> PheLeuAlaM
||||||||||||||||||||| 1012 bp ||||||||||
SerSerGluLeuAlaProLys++ ++PheLeuAlaM
AGCTCGGAGCTGGCACCCAAGgt agTTCCTGGCCA
etValPheGlnAspLeuLeuThrAsnLysAspAspTyrLeuArgAlaSerArgAlaLeuL
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
etValPheGlnAspLeuLeuThrAsnLysAspAspTyrLeuArgAlaSerArgAlaLeuL
TGGTGTTCCAGGACCTCCTGACCAACAAGGATGACTACCTGCGAGCCTCACGGGCCCTGC
euArgGluIleIleLysGlnThrLysHisGluIleAsnPheGlnAlaPheCysLeuGlyL
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
euArgGluIleIleLysGlnThrLysHisGluIleAsnPheGlnAlaPheCysLeuGlyL
TCCGGGAAATCATCAAGCAGACCAAGCACGAGATCAATTTCCAGGCCTTCTGCCTCGGGC
euMetGlnGluArgLysGluProGlnTyrLeuGluMetGluPheLys >>>> Target
|||||||||||||||||||||||||||||||| |||||||||||| 2
euMetGlnGluArgLysGluProGlnTyrLeuAspMetGluPheLys++
TCATGCAGGAGCGCAAAGAGCCCCAGTACCTGGACATGGAGTTCAAGgt
Intron 10 >>>> GluArgPheValValHisIleThrAspValLeuAlaValSerM
70 bp |||||||||||||||||||||||||||||||||||||||||||
++GluArgPheValValHisIleThrAspValLeuAlaValSerM
agGAGCGGTTTGTGGTCCACATTACAGACGTGCTGGCCGTGTCCA
etMetLeuGlyIleThrAlaGlnValLysGluAlaGlyIleAlaTrpAspLysGlyGluL
|||||||||||||||||||||||||||||||||||||| |||||||||||||||||||
etMetLeuGlyIleThrAlaGlnValLysGluAlaGlyValAlaTrpAspLysGlyGluL
TGATGCTGGGCATCACGGCTCAGGTGAAGGAGGCTGGTGTTGCCTGGGACAAAGGAGAAA
ysArg{A} >>>> Target Intron 11 >>>> {sn}LeuGluValLeuArgSer
|||||{|} 677 bp {||}||||||||||||||||||
ysArg{A}++ ++{sn}LeuGluValLeuArgSer
AGAGG{A}gt ag{AT}CTCGAAGTGCTGCGCTCG
PheGlnAsnGlnIleAlaAlaIleGlnArgAspAlaValTrpTrpLeuHisThrValVal
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
PheGlnAsnGlnIleAlaAlaIleGlnArgAspAlaValTrpTrpLeuHisThrValVal
TTCCAGAACCAGATCGCTGCGATCCAGCGGGATGCTGTTTGGTGGCTTCACACAGTGGTC
ProSerIleSerLysLeuAlaProLysAspTyrValHis{Cy} >>>> Target Int
|||||||||||||||||||||||||||||||||||||||{||} 474 b
ProSerIleSerLysLeuAlaProLysAspTyrValHis{Cy}++
CCTTCCATCAGCAAACTCGCCCCCAAGGACTACGTGCAC{TG}gt
ron 12 >>>> {s}LeuHisLysValLeuPheThrGluGlnProGluThrTyrTyrLy
p {|}||||||||||||||||||||||||||||||||||||||||||||
++{s}LeuHisLysValLeuPheThrGluGlnProGluThrTyrTyrLy
ag{C}CTCCACAAGGTGCTCTTCACAGAGCAGCCGGAGACCTACTACAA
sTrpAspAsnTrpProProGluSerAspArg{As} >>>> Target Intron 13 >
|||||||||||||||||||||||||||||||{||} 866 bp
sTrpAspAsnTrpProProGluSerAspArg{As}++
GTGGGACAACTGGCCTCCTGAGAGTGACCGC{AA}gt
>>> {n}PhePheLeuArgLeuCysSerGluValProIleLeuGluAspThrLeuMetA
{|}||||||||||||||||||||||||||||||||||||||||||||||||||||
++{n}PhePheLeuArgLeuCysSerGluValProIleLeuGluAspThrLeuMetA
ag{C}TTCTTCCTGCGCCTCTGCTCAGAGGTCCCCATTCTGGAGGACACACTGATGC
rgIleLeuValIleGlyLeuSerArgGluLeuProLeuGlyProAlaAspAlaMetGluL
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
rgIleLeuValIleGlyLeuSerArgGluLeuProLeuGlyProAlaAspAlaMetGluL
GCATCCTAGTCATCGGACTGTCTCGGGAGCTCCCGCTCGGCCCTGCAGACGCCATGGAGC
euAlaAspHisLeuValLysArgAlaAlaAlaValGlnAlaAsp{A} >>>> Target
||||||||||||||||||||||||||||||||||||||||||||{|} 8
euAlaAspHisLeuValLysArgAlaAlaAlaValGlnAlaAsp{A}++
TCGCTGACCACCTGGTGAAGCGTGCTGCAGCCGTGCAGGCGGAT{G}gt
Intron 14 >>>> {sp}ValGluValLeuLysValGlyArgThrGlnLeuIleAsp
29 bp {||}|||||||||||||||||| ||| ||||||||||||
++{sp}ValGluValLeuLysValGluArgIleGlnLeuIleAsp
ag{AT}GTGGAAGTGCTCAAGGTGGAGAGAATCCAGTTGATCGAT
AlaValLeuAsnLeuCysThrTyrHisHisProGluAsnIleGlnLeuProPro{Gl}
||||||||||||||||||||||||||||||||||||||||||||||||||||||{||}
AlaValLeuAsnLeuCysThrTyrHisHisProGluAsnIleGlnLeuProPro{Gl}++
GCTGTACTGAACCTGTGCACCTACCATCATCCGGAGAACATCCAGCTCCCACCT{GG}gt
>>>> Target Intron 15 >>>> {y}TyrGlnProProAsnLeuAlaIleSerTh
3461 bp {|}|||||||||||||||||||||||||||||
++{y}TyrGlnProProAsnLeuAlaIleSerTh
ag{A}TACCAGCCTCCGAACCTGGCCATCTCGAC
rLeuTyrTrpLysAlaTrpProLeuLeuLeuValValAlaAlaPheAsnProGluAsnIl
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
rLeuTyrTrpLysAlaTrpProLeuLeuLeuValValAlaAlaPheAsnProGluAsnIl
CCTCTACTGGAAGGCCTGGCCCCTCCTGCTGGTGGTCGCCGCGTTCAACCCCGAGAACAT
e{G} >>>> Target Intron 16 >>>> {ly}LeuAlaAlaTrpGluGluTyrP
|{|} 206 bp {||}||||||||||||||||||||||
e{G}++ ++{ly}LeuAlaAlaTrpGluGluTyrP
C{G}gt ag{GC}CTGGCTGCCTGGGAGGAGTACC
roThrLeuLysMetLeuMetGluMetValMetThr{As} >>>> Target Intron
|||||||||||||||||||||||||||||||||||{||} 1315 bp
roThrLeuLysMetLeuMetGluMetValMetThr{As}++
CCACCCTGAAGATGCTCATGGAAATGGTAATGACC{AA}gt
17 >>>> {n}AsnTyrSerTyrProProCysThrLeuThrAspGluGluThrArgThr
{|}||||||||||||||||||||||||||||||||||||||||||||||||
++{n}AsnTyrSerTyrProProCysThrLeuThrAspGluGluThrArgThr
ag{T}AACTACTCCTACCCCCCGTGCACCCTGACGGATGAGGAAACCCGGACA
GluMetLeuAsnArgGluLeuGlnThrAlaGlnArgGluLysGlnGluIleLeuAlaPhe
|||||| ||||||||||||||| ||||||||||||||||||||||||||||||
GluMetIleAsnArgGluLeuGlnIleSerGlnArgGluLysGlnGluIleLeuAlaPhe
GAGATGATTAATCGAGAGTTGCAGATCTCCCAGCGAGAGAAGCAGGAAATCCTGGCATTT
GluGlyHisLeuAlaAlaAlaSerThrLysGlnThrIleThrGluSerSerSerLeuLeu
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GluGlyHisLeuAlaAlaAlaSerThrLysGlnThrIleThrGluSerSerSerLeuLeu
GAGGGACATCTGGCTGCTGCATCCACGAAGCAGACTATCACTGAGAGCAGCAGCCTCCTT
LeuSerGlnLeuThrSerLeuAspProGlnTyrAlaAlaHisThrAlaProProCysAla
|||||||||||||||||||||||||||||||||||| ||| |||
LeuSerGlnLeuThrSerLeuAspProGlnTyrAlaLeuHisProCysProHis---Pro
CTGTCTCAGCTCACCAGCCTGGACCCCCAGTATGCACTGCATCCCTGCCCCCAC---CCC
CysArgArgAsp{Le} >>>> Target Intron 18 >>>> {u}GlyProProAr
||| ||| { } 326 bp { }|||||||||||
CysProArgAsn{Va}+- ++{l}GlyProProAr
TGCCCCAGAAAT{GT}gg ag{A}GGGCCCCCCCG
gArgProProProHisIleLeuAspGlnValLysSerLeuAsnGlnSerLeuArgLeuGl
|||||||||||||||||||||||||||||||||| |||||||||||||||||||||||
gArgProProProHisIleLeuAspGlnValLysGlyLeuAsnGlnSerLeuArgLeuGl
GAGGCCTCCCCCTCACATCCTAGATCAGGTAAAAGGCCTCAACCAGTCCCTCCGCCTTGG
yHisLeuLeuCysArgSerArgAsnProAspPheLeuLeuHisIleIleGlnArgGln
|||||||||||||||||||||||||||||||||||||||| |||||||||||||||
yHisLeuLeuCysArgSerArgAsnProAspPheLeuLeuAsnIleIleGlnArgGln++
ACACCTCCTGTGTCGCAGTCGCAACCCTGACTTCCTCCTCAACATCATCCAGAGGCAGgt
>>>> Target Intron 19 >>>> AlaSerSerGlnSerMetProTrpLeuAlaAs
296 bp ||||||||||||||||||||||||||||||||
++AlaSerSerGlnSerMetProTrpLeuAlaAs
agGCCTCCTCACAGTCCATGCCCTGGCTGGCGGA
pLeuValGlnSer{Se} >>>> Target Intron 20 >>>> {r}GluGlySerL
|||||||||||||{||} 1475 bp {|}||||||||||
pLeuValGlnSer{Se}-- ++{r}GluGlySerL
CCTGGTGCAGTCC{AG}cg ag{C}GAGGGCTCCC
euAspValLeuProValGlnCysLeuCysGluPheLeuLeuHisAspAlaValAspAspA
|||||||||||||||||||||||||||||||||||||||||||||||||| |||||||
euAspValLeuProValGlnCysLeuCysGluPheLeuLeuHisAspAlaAlaAspAspA
TGGACGTGCTGCCCGTGCAGTGCCTGTGCGAGTTCCTGCTGCACGATGCTGCTGACGATG
laAlaSerGlyGluGluAspAspGluGlyGluSerLysGluGlnLysAlaLysLysArgG
|| |||||||||||| ||||||||||||||| ||||||||||||||||||||||
laThrSerGlyGluGluGluAspGluGlyGluSerArgGluGlnLysAlaLysLysArgG
CCACCTCCGGGGAGGAGGAGGATGAGGGCGAGAGCAGAGAGCAGAAGGCCAAGAAGCGGC
ln >>>> Target Intron 21 >>>> ArgGlnGlnLysGlnArgGlnLeuLeuG
|| 78 bp ||||||||||||||||||||||||||||
ln++ ++ArgGlnGlnLysGlnArgGlnLeuLeuG
AGgt agAGGCAGCAGAAGCAGCGGCAGCTGTTGG
lyArgLeuGlnAspLeuLeuLeuGlyProLysAlaAspGluGlnThrThrCysGluValL
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
lyArgLeuGlnAspLeuLeuLeuGlyProLysAlaAspGluGlnThrThrCysGluValL
GCCGCCTGCAGGACCTGCTACTGGGCCCAAAGGCTGACGAGCAGACCACGTGCGAGGTGC
euAspTyrPheLeuArgArgLeuGlySerSerGlnValAlaSerArgValLeuAlaMetL
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
euAspTyrPheLeuArgArgLeuGlySerSerGlnValAlaSerArgValLeuAlaMetL
TTGACTACTTCCTGCGGCGCCTGGGCTCCTCCCAGGTGGCCTCCCGGGTGCTGGCCATGA
ysGlyGluThrLeuProAlaLeuPro{Ly} >>>> Target Intron 22 >>>>
|| |||||| { } 759 bp
ysValArgGlyLeuProLeuValSer{Va}++ ++
AGGTGAGGGGCCTGCCGCTTGTCTCC{GT}gt ag
{s}AlaGlyProAlaHisGluCysLeu-ProGlnGlyLeuSerLeuValLeuSerGluGl
{ } ||||||||| ||||||# |||||||||||||||||||||||||||||
{l}SerGlyProAlaLeuCysCysLeu#LeuGlnGlyLeuSerLeuValLeuSerGluGl
{G}TCGGGCCCAGCTCTGTGCTGTCTGCTTGCAGGGCTTGTCACTGGTGCTTTCGGAGGG
ySerLeuArgAspGlyGluGluLysGluProProMetGluGluAspValGlyAspThrAs
|||||||||||||||||||||||||||||||||| ||||||||| |||||| ||
ySerLeuArgAspGlyGluGluLysGluProProLeuGluGluAspSerGlyAspAlaAs
CAGCCTACGGGATGGGGAAGAGAAAGAACCCCCCCTGGAAGAGGATTCAGGGGATGCCGA
pValLeuGlnGlyTyrGlnTrpLeuLeuArgAspLeuProArgLeuProLeuPheAspSe
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
pMetLeuGlnGlyTyrGlnTrpLeuLeuArgAspLeuProArgLeuProLeuPheAspSe
CATGCTGCAGGGCTACCAGTGGCTGCTGAGGGATCTGCCCAGGCTGCCTCTGTTTGACAG
rValArgSerThrThrAlaLeuAlaLeuGlnGln >>>> Target Intron 23 >>
||||||| |||||||||||||||||||||||| 79 bp
rValArgThrThrThrAlaLeuAlaLeuGlnGln++
CGTGAGGACCACCACCGCCCTGGCACTGCAGCAGgt
>> AlaIleHisMetGluThrAspProGlnThrIleSerAlaTyrLeuIleTyrLeuSe
||||||||||||||||||||||||||||||||||||||||||||| ||||||||
++AlaIleHisMetGluThrAspProGlnThrIleSerAlaTyrLeuValTyrLeuSe
agGCCATCCACATGGAGACCGACCCACAGACCATCAGCGCCTACCTGGTCTACCTGTC
rGlnHisThrProValGluGluGlnAlaGlnHisSerAspLeuAlaLeu >>>> Targ
||||||||||||||||||||||||| |||||||||||||||||||||
rGlnHisThrProValGluGluGlnGlyGlnHisSerAspLeuAlaLeu++
CCAGCACACACCTGTGGAGGAACAAGGCCAGCACAGCGACCTGGCCCTGgt
et Intron 24 >>>> AspValAlaArgLeuValValGluArgSerThrIleMetSe
1138 bp |||||||||||||||||||||||||||||||||||||||||
++AspValAlaArgLeuValValGluArgSerThrIleMetSe
agGATGTGGCTCGGCTCGTTGTGGAGCGTTCCACCATCATGTC
rHisLeuPheSerLysLeuSerProSerAlaAlaSerAspAlaValLeuSerAlaLeuLe
|||||||||||||||||||||| |||||||||||||||||||||||| ||||||||
rHisLeuPheSerLysLeuSerCysSerAlaAlaSerAspAlaValLeuGlyAlaLeuLe
ACACCTCTTCTCGAAGCTGTCCTGCAGTGCTGCTTCAGATGCTGTGCTAGGTGCCCTGCT
uSerIlePheSerArgTyrValArgArgMetArgGlnSerLysGluGlyGluGluValTy
|||||||||||||||||||||||||||||||||| |||||||||||||||||||||||
uSerIlePheSerArgTyrValArgArgMetArgLysSerLysGluGlyGluGluValTy
GTCCATCTTTTCCCGCTATGTGAGGCGCATGCGCAAGAGCAAGGAGGGGGAAGAAGTCTA
rSerTrp >>>> Target Intron 25 >>>> SerGluSerGlnAspGlnValPh
||||||| 77 bp |||||||||||||||||||||||
rSerTrp++ ++SerGluSerGlnAspGlnValPh
CAGCTGGgt agTCGGAGTCTCAGGACCAGGTCTT
eLeuArgTrpSerSerGlyGluThrAlaThrMetHisIleLeuValValHisAlaMetVa
|||||||||| |||||||||||||||||||||||||||||||||||||||||||||||
eLeuArgTrpThrSerGlyGluThrAlaThrMetHisIleLeuValValHisAlaMetVa
CCTGCGCTGGACAAGTGGGGAGACCGCAACCATGCACATCCTCGTGGTGCACGCCATGGT
lIleLeuLeuThrLeuGlyProProArg{A} >>>> Target Intron 26 >>>>
||||||||||||||||||||||||||||{|} 1145 bp
lIleLeuLeuThrLeuGlyProProArg{A}++ +
CATCCTCCTTACACTGGGCCCACCCCGA{G}gt a
{la}AspAspSerGluPheGlnAlaLeuLeuAspIleTrpPheProGluGluLysProL
{||} ||| |||||| ||||||||||||||||||||||||||| |||||||
+{la}GlyAspGlyGluPheHisAlaLeuLeuAspIleTrpPheProGluLysLysProL
g{CT}GGTGATGGCGAGTTCCATGCGTTGTTGGACATCTGGTTTCCGGAGAAGAAACCCC
euProThrAlaPheLeuValAspThrSerGluGluAlaLeuLeuLeuProAspTrpLeuL
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
euProThrAlaPheLeuValAspThrSerGluGluAlaLeuLeuLeuProAspTrpLeuL
TGCCCACTGCCTTCCTGGTGGACACGTCTGAGGAGGCGCTGCTGCTGCCCGACTGGTTGA
ysLeuArgMetIleArgSerGluValLeuArgLeuValAspAla{A} >>>> Target
|||||||||||||||||||||||||| |||||||||||||||{|} 8
ysLeuArgMetIleArgSerGluValProArgLeuValAspAla{A}++
AGTTGCGCATGATTCGCTCAGAGGTCCCACGCCTGGTGGATGCT{G}gt
Intron 27 >>>> {la}LeuGlnAspLeuGluProGlnGlnLeuLeuLeuPheVal
51 bp {||}|||||||||||||||||||||||||||||||||||||||
++{la}LeuGlnAspLeuGluProGlnGlnLeuLeuLeuPheVal
ag{CC}CTGCAGGACCTGGAGCCCCAACAGCTGCTGCTCTTCGTG
GlnSerPheGlyIleProValSerSerMetSerLysLeuLeuGlnPheLeuAspGlnAla
||||||||||||||||||||||||||||||||||||||||||||| ||||||||||||
GlnSerPheGlyIleProValSerSerMetSerLysLeuLeuGlnTyrLeuAspGlnAla
CAGTCCTTTGGCATCCCCGTGTCCAGCATGAGCAAGCTTCTCCAGTACCTAGACCAGGCT
ValAlaHisAspProGlnThrLeuGluGlnAsnIleMetAspLysSerLys
|||||||||||||||||||||||||||||||||||||||||||||||||||
ValAlaHisAspProGlnThrLeuGluGlnAsnIleMetAspLysSerLys
GTGGCCCATGACCCCCAGACCCTGGAGCAGAACATCATGGATAAGAGTAAG
//
|