| Basic information |
| Official Symbol | FRRS1 |
| Description | ferric-chelate reductase 1 |
| Other Aliases | SDFR2, SDR2 |
| Other Description | SDR-2; stromal cell derived factor receptor 2 homolog; stromal cell-derived receptor 2 |
| Mutation type | premature termination 570:L->TGA, premature termination 618:S->TAA |
| Location | Scaffold146687_1:4362892 4330213 - |
| Wiki | Wikipedia GeneCard |
| Sequence |
| FRRS1 |
ATGGCAGTTCCTGGATTCACTCTGGGTATCTCTATACTTCTGCTGTACAC TAGTCCTGTGGCTAATTATCCCAATGGAAAAGTAGCACAGTCGTGCCATG GAATGGTTCCTGAACATGGTCACAGCCCACAGTCTTATCCTGTACACCGC CTTGCAGTGAGTCGGATGACGTTCAGACCCGGAGATCAAATCAAAGTTAC TTTGTCAGGGCGCCCATTTAAAGGCTTTCTCTTAGAAGCTCGTGATGCTG AGGATGTGAGTGGCCCTCCTGTCGGCTCCTTCACGTGGAATGGCAGTCAA GAGATACAGCTTCTGAACTGCAAAGATGTAGAGGGATCAGCGGTGAGTCA TACAAATCCATCCAAAAAAACAGAAATTGAAGTCTACTGGAATGCTCCCA GCAGTGCTTCTAATCACATACAGTTTCTAGTCACGGTTGTCGAGAAGTAT AAAATCTACTGGGTGAAGATTCCTGGCCCTGTAATTTCACAGCCGGATGC ACCTCCTTTTACACCTACAACAACAATCGTACCTTTGTCAACATTACTTC CTCCTGTCTCCCATTTAACCAAACCATTCAATGCTTCAGGCTGTGGGAAC AAGAAGTTCTGTATTAGGAGTCCTTTGAACTGTGACCCAGAGCAGGAGCA TGCCTGCGTCTTCTTGTCCTTCACAAGAGATGGCCACTCGGTGATGGTGG AAATGAGCGGACCCAGTAATGGCTACTTATCCTTTGCGTTTTCTCACGAC CGATGGATGGATGATGATGATGCATACTTGTGTATTCATGAAGATCAGAC TGTGGTCATACAGCCATCCCATTTGACTGGACGAAGTCCCCCTGTGATGG ACCCCAGGGGTCCTCTTGAGGATATGGCTTGGAGGCTGGCGGACGGTATT ATGCAGTGCTCTTTCAGAAGAAACATTACCCTTCCTGGGGTTAAGAATAG ATTTGATCTAAACACAAGCTACTACATATTTCTAGCAGATGGTGCAGCTA ATGATGGTAGAATTTATAAGCATACTCAGCACCCGTTGATTACATATGAA AAATATGACGTGACAGGTGATCCAAAAAACGTAGGAGGATCTCACTCTTC GCTTCTTTTGAAGGCTCATGGTGCCCTAATGTTTGTGGCGTGGATGACTA CTGTCAGCACAGGTGTACTGATTGCCCGGTTCTTCAGATCTGTTTGGTCG AAAGCTTTCTTCCTTGGTGAAGCAGCTTGGTTTCAGGTGCATCGGATGCT CATGTTCACTACATCCGCTCTCACCTGCGTTGCTTTTGTTATGCCTTTCG TATACAGAGGAGGCTGGAGCTGGCATGCAGGTTATCACCCCTACCTTGGT TGCATAGTGATGACTATTGCAGTTCTTCAGCCTTTTCTGGCAGCCTTCAG GCCACCTATACATGACCCAAGGAGGCAAATGTTTAACTGGACTCACTGGA GTATGGGAACAGCTGCTAGAATAATAGCAGTGGCAGCCATGTTCCTGGGA ATGGATTTACCAGGACTGAATCTTCCTTATCCACGGAAAACCTATGCCAT GATTGGATTTGTAGCCTGGCATGTTGGGACTGAAATTATTTTGGAGATAC ATGCTTACCGACTCTCTCGAAAAGGTAACGAACATGCTTATCTCTATTTT TCTTCCAGGGTCATGCTTTTAAAAAGGCAGTGTTGGCAATTTATGTCTGT GGAAATGTGACTTTTCTCATCATATTCTTATCTGCAATCAACCATCTATG AGCAAGTGAAATCTTGGGCTGTCGTAGGCCATGGGATAATTATCATCAAA CCAAAGAAACTTGAAGCCTGTACTGACTGCCTGGGGTATATTTATGAATT CTAATTTGAAAGGCCAGGATCATGTCTA |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 626 | 1 | 626 | Premature termination 570:L->TGA, Premature termination 618:S->TAA |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
MetAlaValSerGlyPheThrLeuGlyThrCysIleLeuLeuLeuHisIleSerTyrVal
||||||||| ||||||||||||||| |||||||||||| ||| |||
MetAlaValProGlyPheThrLeuGlyIleSerIleLeuLeuLeuTyrThrSerProVal
ATGGCAGTTCCTGGATTCACTCTGGGTATCTCTATACTTCTGCTGTACACTAGTCCTGTG
AlaAsnTyrProAsnGlyLysValThrGlnSerCysHisGlyMetIleProGluHisGly
|||||||||||||||||||||||| |||||||||||||||||| ||||||||||||
AlaAsnTyrProAsnGlyLysValAlaGlnSerCysHisGlyMetValProGluHisGly
GCTAATTATCCCAATGGAAAAGTAGCACAGTCGTGCCATGGAATGGTTCCTGAACATGGT
HisSerProGlnSerValProValHisAspIleTyrValSerGlnMetThrPheArgPro
||||||||||||||| ||||||||| |||||| |||||||||||||||
HisSerProGlnSerTyrProValHisArgLeuAlaValSerArgMetThrPheArgPro
CACAGCCCACAGTCTTATCCTGTACACCGCCTTGCAGTGAGTCGGATGACGTTCAGACCC
GlyAspGlnIleGlu{V} >>>> Target Intron 1 >>>> {al}ThrLeuSer
|||||||||||| {|} 1710 bp {||}|||||||||
GlyAspGlnIleLys{V}++ ++{al}ThrLeuSer
GGAGATCAAATCAAA{G}gt ag{TT}ACTTTGTCA
GlyHisProPheLysGlyPheLeuLeuGluAlaArgAsnAlaGluAspLeuAsnGlyPro
||| |||||||||||||||||||||||||||||| ||||||||| ||||||
GlyArgProPheLysGlyPheLeuLeuGluAlaArgAspAlaGluAspValSerGlyPro
GGGCGCCCATTTAAAGGCTTTCTCTTAGAAGCTCGTGATGCTGAGGATGTGAGTGGCCCT
ProIleGlySerPheThrLeuIleAspSerGluValSerGlnLeuLeuThrCysGluAsp
||| |||||||||||| ||| ||||||||| ||| |||
ProValGlySerPheThrTrpAsnGlySerGlnGluIleGlnLeuLeuAsnCysLysAsp
CCTGTCGGCTCCTTCACGTGGAATGGCAGTCAAGAGATACAGCTTCTGAACTGCAAAGAT
IleGln >>>> Target Intron 2 >>>> GlySerAlaValSerHisArgSerA
1299 bp ||||||||||||||||||
ValGlu++ ++GlySerAlaValSerHisThrAsnP
GTAGAGgt agGGATCAGCGGTGAGTCATACAAATC
laSerLysLysThrGluIleLysValTyrTrpAsnAlaProSerSerAlaProAsnHisT
|||||||||||||||||| ||||||||||||||||||||||||||| ||||||
roSerLysLysThrGluIleGluValTyrTrpAsnAlaProSerSerAlaSerAsnHisI
CATCCAAAAAAACAGAAATTGAAGTCTACTGGAATGCTCCCAGCAGTGCTTCTAATCACA
hrGlnPhe{Le} >>>> Target Intron 3 >>>> {u}ValThrValValGluL
||||||{||} 1106 bp {|}||||||||||||||||
leGlnPhe{Le}++ ++{u}ValThrValValGluL
TACAGTTT{CT}gt ag{A}GTCACGGTTGTCGAGA
ysTyrLysIleTyrTrpValLysIleProGlyProIleIleSerGlnProAsnAlaPheP
||||||||||||||||||||||||||||||||||| |||||||||||| ||| |
ysTyrLysIleTyrTrpValLysIleProGlyProValIleSerGlnProAspAlaProP
AGTATAAAATCTACTGGGTGAAGATTCCTGGCCCTGTAATTTCACAGCCGGATGCACCTC
roPheThrThrProLysAlaThrValValProLeuProThrLeuProProValSerHisL
|||||||| ||| |||||||||||||||||||
roPheThrProThrThrThrIleValProLeuSerThrLeuLeuProProValSerHisL
CTTTTACACCTACAACAACAATCGTACCTTTGTCAACATTACTTCCTCCTGTCTCCCATT
euThrLysPro >>>> Target Intron 4 >>>> PheSerAlaSerAspCysGl
||||||||||| 3490 bp ||| |||||| |||||
euThrLysPro++ ++PheAsnAlaSerGlyCysGl
TAACCAAACCAgt agTTCAATGCTTCAGGCTGTGG
yAsnLysLysPheCysIleArgSerProLeuAsnCysAspProGluLysGluAlaSerCy
|||||||||||||||||||||||||||||||||||||||||||||| ||| ||
yAsnLysLysPheCysIleArgSerProLeuAsnCysAspProGluGlnGluHisAlaCy
GAACAAGAAGTTCTGTATTAGGAGTCCTTTGAACTGTGACCCAGAGCAGGAGCATGCCTG
sValPheLeuSerPheThrArgAspAspGlnSerValMetValGluMetSerGlyProSe
||||||||||||||||||||||||| |||||||||||||||||||||||||||||
sValPheLeuSerPheThrArgAspGlyHisSerValMetValGluMetSerGlyProSe
CGTCTTCTTGTCCTTCACAAGAGATGGCCACTCGGTGATGGTGGAAATGAGCGGACCCAG
rLysGlyTyrLeuSerPheAlaLeuSerHisAspGlnTrpMet >>>> Target Int
| |||||||||||||||||| ||||||||| |||||| 3452 b
rAsnGlyTyrLeuSerPheAlaPheSerHisAspArgTrpMet++
TAATGGCTACTTATCCTTTGCGTTTTCTCACGACCGATGGATGgt
ron 5 >>>> GlyAspAspAspAlaTyrLeuCysIleHisGluAspGlnThrValTyr
p ||||||||||||||||||||||||||||||||||||||||||
--AspAspAspAspAlaTyrLeuCysIleHisGluAspGlnThrValVal
gtGATGATGATGATGCATACTTGTGTATTCATGAAGATCAGACTGTGGTC
IleGlnProSerHisLeuThrGlyArgSerHisProValMetAspSerArg >>>> Ta
|||||||||||||||||||||||||||||| |||||||||||| |||
IleGlnProSerHisLeuThrGlyArgSerProProValMetAspProArg++
ATACAGCCATCCCATTTGACTGGACGAAGTCCCCCTGTGATGGACCCCAGGgt
rget Intron 6 >>>> AspThrLeuGluAspMetAlaTrpArgLeuAlaAspGlyV
1189 bp |||||||||||||||||||||||||||||||||
++GlyProLeuGluAspMetAlaTrpArgLeuAlaAspGlyI
agGGTCCTCTTGAGGATATGGCTTGGAGGCTGGCGGACGGTA
alMetGlnCysSerPheArgArgAsnIleThrLeuProGlyValLysAsnArgPheAspL
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
leMetGlnCysSerPheArgArgAsnIleThrLeuProGlyValLysAsnArgPheAspL
TTATGCAGTGCTCTTTCAGAAGAAACATTACCCTTCCTGGGGTTAAGAATAGATTTGATC
euAsnThrSerTyrTyrIlePheLeuAlaAspGlyAlaAlaAsnAsp{G} >>>> Tar
|||||||||||||||||||||||||||||||||||||||||||||||{|}
euAsnThrSerTyrTyrIlePheLeuAlaAspGlyAlaAlaAsnAsp{G}++
TAAACACAAGCTACTACATATTTCTAGCAGATGGTGCAGCTAATGAT{G}gt
get Intron 7 >>>> {ly}ArgIleTyrLysHisSerGlnGlnProLeuIleThrT
5772 bp {||}||||||||||||||| ||| |||||||||||||
++{ly}ArgIleTyrLysHisThrGlnHisProLeuIleThrT
ag{GT}AGAATTTATAAGCATACTCAGCACCCGTTGATTACAT
yrGluLysTyrAspValThrAspSerProLysAsnIleGlyGlySerHisSerValLeuL
|||||||||||||||||||| ||||||||| ||||||||||||||| ||||
yrGluLysTyrAspValThrGlyAspProLysAsnValGlyGlySerHisSerSerLeuL
ATGAAAAATATGACGTGACAGGTGATCCAAAAAACGTAGGAGGATCTCACTCTTCGCTTC
euLeuLysValHis{G} >>>> Target Intron 8 >>>> {ly}AlaLeuMetP
|||||||| |||{|} 1595 bp {||}||||||||||
euLeuLysAlaHis{G}++ ++{ly}AlaLeuMetP
TTTTGAAGGCTCAT{G}gt ag{GT}GCCCTAATGT
heValAlaTrpMetThrThrValSerIleGlyValLeuValAlaArgPhePheLysProV
|||||||||||||||||||||||||| ||||||||| |||||||||||| |
heValAlaTrpMetThrThrValSerThrGlyValLeuIleAlaArgPhePheArgSerV
TTGTGGCGTGGATGACTACTGTCAGCACAGGTGTACTGATTGCCCGGTTCTTCAGATCTG
alTrpSerLysAlaPheLeuLeuGlyGluAlaAlaTrpPheGln >>>> Target In
||||||||||||||||| |||||||||||||||||||||||| 1546
alTrpSerLysAlaPhePheLeuGlyGluAlaAlaTrpPheGln++
TTTGGTCGAAAGCTTTCTTCCTTGGTGAAGCAGCTTGGTTTCAGgt
tron 9 >>>> ValHisArgMetLeuMetPheThrThrThrValLeuThrCysIleAl
bp ||||||||||||||||||||||||||| ||||||||| ||
++ValHisArgMetLeuMetPheThrThrSerAlaLeuThrCysValAl
agGTGCATCGGATGCTCATGTTCACTACATCCGCTCTCACCTGCGTTGC
aPheValMetProPheIleTyrArgGlyGlyTrpSerArg >>>> Target Intron
|||||||||||||||| |||||||||||||||||| 6186 bp
aPheValMetProPheValTyrArgGlyGlyTrpSerTrp++
TTTTGTTATGCCTTTCGTATACAGAGGAGGCTGGAGCTGGgt
10 >>>> HisAlaGlyTyrHisProTyrLeuGlyCysIleValMetThrLeuAlaVa
|||||||||||||||||||||||||||||||||||||||||| |||||
++HisAlaGlyTyrHisProTyrLeuGlyCysIleValMetThrIleAlaVa
agCATGCAGGTTATCACCCCTACCTTGGTTGCATAGTGATGACTATTGCAGT
lLeuGlnProLeuLeuAlaValPheArgProProLeuHisAspPro{Ar} >>>> Tar
|||||||||| |||||| |||||||||||| |||||||||{||}
lLeuGlnProPheLeuAlaAlaPheArgProProIleHisAspPro{Ar}++
TCTTCAGCCTTTTCTGGCAGCCTTCAGGCCACCTATACATGACCCA{AG}gt
get Intron 11 >>>> {g}ArgGlnMetPheAsnTrpThrHisTrpSerMetGlyT
251 bp {|}|||||||||||||||||||||||||||||||||||||
++{g}ArgGlnMetPheAsnTrpThrHisTrpSerMetGlyT
ag{G}AGGCAAATGTTTAACTGGACTCACTGGAGTATGGGAA
hrAlaAlaArgIleIleAla{V} >>>> Target Intron 12 >>>> {al}Ala
||||||||||||||||||||{|} 548 bp {||}|||
hrAlaAlaArgIleIleAla{V}++ ++{al}Ala
CAGCTGCTAGAATAATAGCA{G}gt ag{TG}GCA
AlaMetPheLeuGlyMetAspLeuProGlyLeuAsnLeuProAspSerTrpLysThrTyr
|||||||||||||||||||||||||||||||||||||||||| |||||||||
AlaMetPheLeuGlyMetAspLeuProGlyLeuAsnLeuProTyrProArgLysThrTyr
GCCATGTTCCTGGGAATGGATTTACCAGGACTGAATCTTCCTTATCCACGGAAAACCTAT
AlaMetThrGlyPheValAlaTrpHisValGlyThrGluValValLeuGluLeuLysTyr
|||||| |||||||||||||||||||||||||||||| ||||||
AlaMetIleGlyPheValAlaTrpHisValGlyThrGluIleIleLeuGluIleHisAla
GCCATGATTGGATTTGTAGCCTGGCATGTTGGGACTGAAATTATTTTGGAGATACATGCT
TrpMetMetThrGluPheArgSerPheSerHis{L} >>>> Target Intron 13
{ } 2658 bp
TyrArgLeuSerArgLysGlyAsnGluHisAla{T}+-
TACCGACTCTCTCGAAAAGGTAACGAACATGCT{T}ga
>>>> {eu}LeuGlnTrpLysGlnArgValMetLeuLeuLysArgGlnCysTrpGlnPh
{ }||| |||||||||||||||||||||||||||||||||||
+-{yr}LeuTyrPheSerSerArgValMetLeuLeuLysArgGlnCysTrpGlnPh
at{AT}CTCTATTTTTCTTCCAGGGTCATGCTTTTAAAAAGGCAGTGTTGGCAATT
eMetSerValGlyMetLeuLeuPheSerSerTyrPheTyrLeuGlnSerThrIleTyrGl
|||||||||| ||| ||||||||||||||| |||||||||||||||||||||||
eMetSerValGluMet***LeuPheSerSerTyrSerTyrLeuGlnSerThrIleTyrGl
TATGTCTGTGGAAATGTGACTTTTCTCATCATATTCTTATCTGCAATCAACCATCTATGA
uGlnAlaLysThrLeuAlaPheAlaGlyGlnValIleIleIleIleLysProLysLysLe
|||| ||| ||| ||| ||||||||||||||||||||||||||
uGlnValLysSerTrpAlaValValGlyHisGlyIleIleIleIleLysProLysLysLe
GCAAGTGAAATCTTGGGCTGTCGTAGGCCATGGGATAATTATCATCAAACCAAAGAAACT
uGluAlaCysProAspCysLeuGluHisIleCysGluPheSerLeuGlyArgLeuGlySe
|||||||||| ||||||||| ||| |||||| ||| |||||
uGluAlaCysThrAspCysLeuGlyTyrIleTyrGluPhe***PheGluArgProGlySe
TGAAGCCTGTACTGACTGCCTGGGGTATATTTATGAATTCTAATTTGAAAGGCCAGGATC
rCysLeu
|||||||
rCysLeu
ATGTCTA
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