| Basic information |
| Official Symbol | FAM63A |
| Description | family with sequence similarity 63, member A |
| Other Aliases | RP11-316M1.5 |
| Other Description | protein FAM63A |
| Mutation type | premature termination 27:W->TGA, premature termination 47:L->TAG |
| Location | Scaffold145814_1:1505591 1515124 + |
| Wiki | Wikipedia GeneCard |
| Sequence |
| FAM63A |
TTGGCCTATCAAGTGTGACTTAGGCAAGTCCCTGAGGTCAGTGAACACCT TCGGTGGCCCCTGGTTGACTTCTTTTAGACCATGGAACACCATCAGCCTG AATATCCAGTCCCTGGGAAGGCTAAGAATGCAGAAGAAGTCACCCCTGAA AACCAGGAGGTCCTGTCAGGACCAGAAGAGGACCATCAGGACGGGGATGC TAGAGATGCTGATGAGGTGCCTGTAGGACAGGAGCCAGGACACCAAGCCT TGCCGTCTGCCCGAGGTGGGGATAGCCTCGAATCCCCTCCACCTGAAGCT AGCTCAAGTCTACTGGGGCCAGCCCACGGGATATCACCCGAGGTAGAGAC GGTGGGGGCATGCTCTAGGCCTCAGGAGCTCCCCCAGTCTCCCAGGACCC GACAGCCTGAGCCAGATTTCTACTGTGTAAAGTGGATTCCCTGGAAGGGA GAGCGGACACCCATCATCACCCAGAGCACAAATGGTCCATGCCCCCTCCT TGCCATCATGAACATCCTCTTTCTTCAGTGGAAGGTGAAGCTGCCCCCCC AGAAGGAAGTGATCACGTCGGATGAGCTCATGACCCACCTTGGAAACTGC CTCCTGTCCATCAAGCCCCAGGAGAAGTCCGAAGGACTTCAGCTTAATTT TCAGCAGAATGTGAACGATGCGATGACAGTGCTGCCTAAACTGGCCACGG GCCTGGACGTCAACGTGAGGTTCACGGGTGTCTCCGACTTCGAGTACACG CCGGAGTGCAGTGTCTTTGACCTCCTAGGCATACCTCTATACCATGGCTG GCTGGTTGACCCACAGAGTCCTGAGGCGGTGAGTGCGGTGGGGAAGCTGA GCTACAACCAGCTGGTGGAGAAGATCATCACCTGCAAACACTCCAGCGAC ACCAACCTCGTGACGGAAGGCCTGATTGCAGAGCAGTTCCTGGAGACCAC GGCGGCGCAGCTGACCTACCATGGACTGTGCGAGCTAACGGCAGGCGCCA AGGGGGAGCTTAGCGTCTTTTTCCGAAACAACCACTTTAGCACTCTGACT AAACACAAGAGTCACTTGTACCTCCTGGTCACCGACCAGGGCTTTCTGCA GGAGGAGCAGGTGGTGTGGGAGAGCCTGCACAACGTGGATGGAGACAGCT GCTTCTGCGACTCCGACTTTCATCTAAGCCATTCCCTGGGCAAGGGGCCT GGAGTGGAAAGTGGGAGTAGCTCCCCAGAAAAGCAGCTGCAGGTGGACCA GGACTATCTGATTGCCCTGTCCCTGCAGCAGCAGCAGCCACAGGGCTCGC TGGCCCTGAGCGACTTGGAGCTGGCCCAGCAGCTTCCGCAGGGGGAGTCT TCAGGCAGCCCCGCCCAGCAGAGGTTGTGGGATGACCCATTGTCAAATCC CATACAGGGAAGAGGAGCCGCACCCGGCCGGCCAGGTGGGGAGCGTCGAC GGCCGAAGCACGAGTCAGACTGTGTCCTGCTG |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 517 | 22 | 517 | Premature termination 27:W->TGA, Premature termination 47:L->TAG |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
PheAlaSerGlnAlaTrpLeuArgGlnValProGluValSerLysHisLeuGlnCysPro
||| ||| |||||||||||||||||||||||| |||||| |||
LeuAlaTyrGlnVal***LeuArgGlnValProGluValSerGluHisLeuArgTrpPro
TTGGCCTATCAAGTGTGACTTAGGCAAGTCCCTGAGGTCAGTGAACACCTTCGGTGGCCC
SerAlaLysSerLeuLeuThrMetGluTyrHisGlnProGluAspProAlaProGlyLys
||||||||| |||||||||||| ||| |||||||||
LeuValAspPhePhe***ThrMetGluHisHisGlnProGluTyrProValProGlyLys
CTGGTTGACTTCTTTTAGACCATGGAACACCATCAGCCTGAATATCCAGTCCCTGGGAAG
AlaGlyThrAlaGluAlaValIleProGluAsnHisGluValLeuAlaGlyProAspGlu
||| |||||| ||| ||||||||| ||||||||| |||||| |||
AlaLysAsnAlaGluGluValThrProGluAsnGlnGluValLeuSerGlyProGluGlu
GCTAAGAATGCAGAAGAAGTCACCCCTGAAAACCAGGAGGTCCTGTCAGGACCAGAAGAG
HisProGlnAspThrAspAlaArgAspAlaAspGlyGluAlaArgGluArgGluProAla
|||||| |||||||||||||||||| ||||||
AspHisGlnAspGlyAspAlaArgAspAlaAspGluValProValGlyGlnGluProGly
GACCATCAGGACGGGGATGCTAGAGATGCTGATGAGGTGCCTGTAGGACAGGAGCCAGGA
AspGlnAlaLeuLeuProSerGlnCysGlyAspAsnLeuGluSerProLeuProGluAla
||||||||| |||||| |||||||||||| |||||||||
HisGlnAlaLeuProSerAlaArgGlyGlyAspSerLeuGluSerProProProGluAla
CACCAAGCCTTGCCGTCTGCCCGAGGTGGGGATAGCCTCGAATCCCCTCCACCTGAAGCT
SerSerAlaProProGlyProThrLeuGlyThrLeuProGluValGluThrIleArgAla
|||||| |||||| ||| ||||||||||||||| |||
SerSerSerLeuLeuGlyProAlaHisGlyIleSerProGluValGluThrValGlyAla
AGCTCAAGTCTACTGGGGCCAGCCCACGGGATATCACCCGAGGTAGAGACGGTGGGGGCA
CysSerMetProGlnGluLeuProGlnSerProArgThrArgGlnProGluProAspPhe
|||||| |||||||||||||||||||||||||||||||||||||||||||||||||||
CysSerArgProGlnGluLeuProGlnSerProArgThrArgGlnProGluProAspPhe
TGCTCTAGGCCTCAGGAGCTCCCCCAGTCTCCCAGGACCCGACAGCCTGAGCCAGATTTC
TyrCysValLysTrpIleProTrpLysGlyGluGlnThrProIleIleThrGlnSerThr
||||||||||||||||||||||||||||||||| ||||||||||||||||||||||||
TyrCysValLysTrpIleProTrpLysGlyGluArgThrProIleIleThrGlnSerThr
TACTGTGTAAAGTGGATTCCCTGGAAGGGAGAGCGGACACCCATCATCACCCAGAGCACA
AsnGlyProCysProLeuLeuAlaIleMetAsnIleLeuPheLeuGlnTrpLys >>>>
||||||||||||||||||||||||||||||||||||||||||||||||||||||
AsnGlyProCysProLeuLeuAlaIleMetAsnIleLeuPheLeuGlnTrpLys++
AATGGTCCATGCCCCCTCCTTGCCATCATGAACATCCTCTTTCTTCAGTGGAAGgt
Target Intron 1 >>>> ValLysLeuProProGlnLysGluValIleThrSerA
1029 bp |||||||||||||||||||||||||||||||||||||
++ValLysLeuProProGlnLysGluValIleThrSerA
agGTGAAGCTGCCCCCCCAGAAGGAAGTGATCACGTCGG
spGluLeuMetAlaHisLeu{G} >>>> Target Intron 2 >>>> {ly}AsnC
||||||||||| ||||||{|} 862 bp {||}||||
spGluLeuMetThrHisLeu{G}++ ++{ly}AsnC
ATGAGCTCATGACCCACCTT{G}gt ag{GA}AACT
ysLeuLeuSerIleLysProGlnGluLysSerGluGlyLeuGlnLeuAsnPheGlnGln
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ysLeuLeuSerIleLysProGlnGluLysSerGluGlyLeuGlnLeuAsnPheGlnGln+
GCCTCCTGTCCATCAAGCCCCAGGAGAAGTCCGAAGGACTTCAGCTTAATTTTCAGCAGg
>>>> Target Intron 3 >>>> AsnValAspAspAlaMetThrValLeuProLy
292 bp |||||| |||||||||||||||||||||||
+ ++AsnValAsnAspAlaMetThrValLeuProLy
t agAATGTGAACGATGCGATGACAGTGCTGCCTAA
sLeuAlaThrGlyLeuAspValAsnValArgPheThrGlyValSerAspPheGluTyrTh
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
sLeuAlaThrGlyLeuAspValAsnValArgPheThrGlyValSerAspPheGluTyrTh
ACTGGCCACGGGCCTGGACGTCAACGTGAGGTTCACGGGTGTCTCCGACTTCGAGTACAC
rProGluCysSerValPheAspLeuLeuGlyIleProLeuTyrHisGlyTrpLeuValAs
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
rProGluCysSerValPheAspLeuLeuGlyIleProLeuTyrHisGlyTrpLeuValAs
GCCGGAGTGCAGTGTCTTTGACCTCCTAGGCATACCTCTATACCATGGCTGGCTGGTTGA
pProGln >>>> Target Intron 4 >>>> SerProGluAlaValArgAlaVal
||||||| 2152 bp ||||||||||||||| ||||||
pProGln++ ++SerProGluAlaValSerAlaVal
CCCACAGgt agAGTCCTGAGGCGGTGAGTGCGGTG
GlyLysLeuSerTyrAsnGlnLeuValGluArgIleIleThrCysLysHisSerSerAsp
|||||||||||||||||||||||||||||| |||||||||||||||||||||||||||
GlyLysLeuSerTyrAsnGlnLeuValGluLysIleIleThrCysLysHisSerSerAsp
GGGAAGCTGAGCTACAACCAGCTGGTGGAGAAGATCATCACCTGCAAACACTCCAGCGAC
ThrAsnLeuValThrGlu{G} >>>> Target Intron 5 >>>> {ly}LeuIle
||||||||||||||||||{|} 621 bp {||}||||||
ThrAsnLeuValThrGlu{G}++ ++{ly}LeuIle
ACCAACCTCGTGACGGAA{G}gt ag{GC}CTGATT
AlaGluGlnPheLeuGluThrThrAlaAlaGlnLeuThrTyrHisGlyLeuCysGluLeu
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
AlaGluGlnPheLeuGluThrThrAlaAlaGlnLeuThrTyrHisGlyLeuCysGluLeu
GCAGAGCAGTTCCTGGAGACCACGGCGGCGCAGCTGACCTACCATGGACTGTGCGAGCTA
ThrAlaAlaAla{L} >>>> Target Intron 6 >>>> {ys}GluGlyGluLeu
|||||| |||{|} 32 bp {||} |||||||||
ThrAlaGlyAla{L}+- ++{ys}---GlyGluLeu
ACGGCAGGCGCC{A}ga ag{AG}---GGGGAGCTT
SerValPhePheArgAsnAsnHisPheSerThrMetThrLysHisLys >>>> Targe
||||||||||||||||||||||||||||||||| |||||||||||| 1
SerValPhePheArgAsnAsnHisPheSerThrLeuThrLysHisLys++
AGCGTCTTTTTCCGAAACAACCACTTTAGCACTCTGACTAAACACAAGgt
t Intron 7 >>>> SerHisLeuTyrLeuLeuValThrAspGlnGlyPheLeuGlnG
860 bp |||||||||||||||||||||||||||||||||||||||||||
++SerHisLeuTyrLeuLeuValThrAspGlnGlyPheLeuGlnG
agAGTCACTTGTACCTCCTGGTCACCGACCAGGGCTTTCTGCAGG
luGluGlnValValTrpGluSerLeuHisAsnValAspGlyAspSerCysPheCysAspS
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
luGluGlnValValTrpGluSerLeuHisAsnValAspGlyAspSerCysPheCysAspS
AGGAGCAGGTGGTGTGGGAGAGCCTGCACAACGTGGATGGAGACAGCTGCTTCTGCGACT
erAspPheHisLeuSerHisSerLeuGlyLysGlyProGlyAlaGluGlyGlySerGlyS
||||||||||||||||||||||||||||||||||||||||| ||| |||||| |
erAspPheHisLeuSerHisSerLeuGlyLysGlyProGlyValGluSerGlySerSerS
CCGACTTTCATCTAAGCCATTCCCTGGGCAAGGGGCCTGGAGTGGAAAGTGGGAGTAGCT
erProGluThrGlnLeuGlnValAspGln >>>> Target Intron 8 >>>> As
|||||||| |||||||||||||||||| 993 bp ||
erProGluLysGlnLeuGlnValAspGln++ ++As
CCCCAGAAAAGCAGCTGCAGGTGGACCAGgt agGA
pTyrLeuIleAlaLeuSerLeuGlnGlnGlnGlnProArgGlyProLeuGlyLeuThrAs
||||||||||||||||||||||||||||||||||||| ||| ||| ||| ||
pTyrLeuIleAlaLeuSerLeuGlnGlnGlnGlnProGlnGlySerLeuAlaLeuSerAs
CTATCTGATTGCCCTGTCCCTGCAGCAGCAGCAGCCACAGGGCTCGCTGGCCCTGAGCGA
pLeuGluLeuAlaGlnGlnLeuGlnGlnGluGluTyrGlnGlnGlnGlnAlaAla >>>
|||||||||||||||||||||| ||| ||| |||
pLeuGluLeuAlaGlnGlnLeuProGlnGlyGluSerSerGlySerProAlaGln+-
CTTGGAGCTGGCCCAGCAGCTTCCGCAGGGGGAGTCTTCAGGCAGCCCCGCCCAGgc
> Target Intron 9 >>>> GlnProValArgMetArgThrArgValLeuSerLeu
211 bp |||
--GlnArgLeuTrpAspAspProLeuSerAsnProIle
tcCAGAGGTTGTGGGATGACCCATTGTCAAATCCCATA
GlnGlyArgGlyAlaThrSerGlyArgProAlaGlyGluArgArgGlnArgProLysHis
||||||||||||||| ||||||||| |||||||||||| ||||||||||||
GlnGlyArgGlyAlaAlaProGlyArgProGlyGlyGluArgArg---ArgProLysHis
CAGGGAAGAGGAGCCGCACCCGGCCGGCCAGGTGGGGAGCGTCGA---CGGCCGAAGCAC
GluSerAspCysIleLeuLeu
|||||||||||| ||||||
GluSerAspCysValLeuLeu
GAGTCAGACTGTGTCCTGCTG
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