| Basic information |
| Official Symbol | EXOC7 |
| Description | exocyst complex component 7 |
| Other Aliases | 2-5-3p, EX070, EXO70, EXOC1, Exo70p, YJL085W |
| Other Description | exocyst complex component Exo70 |
| Mutation type | Delete and frame-shift 306:T->C |
| Location | Scaffold000159_1:5864606 5884890 + |
| Wiki | Wikipedia GeneCard |
| Sequence |
| EXOC7 |
ATGATCCCCCCGCAAGAGGCGTCCGCCCGGCGGCGGGAGATCGAGGACAAGCTGAAGCAG GAGGAGGAGACGCTGTCCTTCATCCGAGACAGCCTGGAGAAGAGCGACCAGCTCACCAAG AACATGGTGTCTATCCTGTCGTCCTTTGAGAGCCGCCTCATGAAGCTGGAGAACTCCATC ATCCCTGTGCACAAGCAGACAGAGAACCTGCAGCGGCTGCAGGAGAATGTAGAGAAGACA CTGTCCTGCCTAGACCATGTCATCAGCTACTACCACGTGGCCAGCGACACTGAGAAGATC ATCAGGGAGCCCACAGGTAGGCTGGAAGAGTACCTGGGGAGCATGGCCAAGATCCAGAAG GCTGTGGAATATTTCCAGGACAATAGCCCAGATAGTCCAGAGCTCAACAAAGTGAAGCTG CTGTTTGAGCGGGGAAAGGAGTCTCTGGAGTCCGAGTTCCGCAGCCTGATGACCCGGCAC AGTAAGGTCGTCTCCCCTGTGCTCATCCTGGATCTGATCAGTGGTGATGACGAGCTGGAC GTCTCGGAGGACGTGGTCCTGGAGCACCTGCCCGAGAGCGTGCTGCAGGATGTGATCCGC ATCTCCCGCTGGCTGGTGGAATACGGCCACAACCAATTCATGAATGTCTACTACCAGATT CGCTCCAGCCAGCTGGACCGCTCCATCAAGGGCCTGAAGGAGCATTTTCGGAAATGCAGT TCTTCTTCTGGGGTTCCCTACTCCCCTGCCATCCCCAACAAGAGGAAAGACACACCTACC AAGAAGCCAGTCAAGCGGCCAACGATCCGTAAGGCTCAGAACCTTCTGAAACAGTATTCC CAGCATGGTCTAGATGGGAAAAAGGGGGGCTCTAACCTCATTCCTCTGGAAGGTCTTCTT CCCGTTCCCCAAGGGGCAGCCGCCTGGCCCCTGGATAAACGCTGCTTGTGTTTGTGCGGC TGACATCTCGCTAGGTCACGAGCATGATTTCCGAGTTAAGCACCTGCCCGAGGCCCTGAA CGACAAGCACAGGCTGCTGGCCAGAGACGACACGCTGGACGTGGAGACCGACGCCTACAT CCACTGCGTCAGTGCCTTCGTCAGGCTGGCCCAGAGCGAGTACCAGCTGCTGACCGACGT CATCCCTGAGCACCACCAGAAGAAAACCTTCGACTCCTTGATACAGGACGCGCTGGACGG GCTGATCCTGGAGGGGGACAACATCGTGTGTGCCGCCCGCAAGGCCATCATGCGGCACGA CTTCCCCACGGTGCTCACCGTCTTCCCCATCCTGCGGCACCTCAAGCAGACCAAGCCCGA GTTCGACCAGGTGCTCCAGGGCACGGCCGCCAGCACCAAGAACAAACTGCCCAGCCTCAT CACCTCCATGGAGACCATCGGGGCGAAAGCGCTGGAGGACTTTGCCGACAACATCAAGAA TGACCCGGACAAGGAGTACAACATGCCCAAGGATGGCACCGTGCACGAGCTCACAAGCAA CGCCATCCTCTTCCTGCAGCAGCTTCTGGACTTCCAGGAGACAGCAGGTGCCATGCTGGC CTCCCAAACCAGCTCCTCGGCCACCAGCCACAGCTCCGTGGTCAGCAGGCGCCTGCTGAG CACCTACATCAAAGTCCTAGGCAACCTGCAGCTGAACTTGCTGAGCAAGTCCAAGGTGTA CGAGGACCCCGCTCTGAGCGCCATCTTCCTGCACAACAACTACAACTACATCCTCAAGTC CCTGGAGTCTGAGCTGATCCAGCTGGTGGCTGTGACCCAGAAGACAGCGGAGCGCTCCTA CCGGGAGCACATTGAGCAGCAGATCCAGACCTACCAGCGCTGGGTGAAGGTGACGGACTA CATCACAGAGAAGAACCTGCCTGTGTTCCAGCCTGGGGTCAAGCTCCGGGACAAGGAACG GCAGATGATCAAGGAGCGTTTTAAGGGTTTCAATGATGGTCTCGAAGAATTGTGCAAGAT CCAGAAAGCCTGGGCTATTCCCGACACGGAGCAGAGGGACAAGATTCGCCAGGCTCAGAA AAACGTTGTCAAGGAGACCTACGGGGCCTTCCTGCACTATGGTGGCGTGCCCTTCACCAA GAACCCCGAGAAGTACATCAAGTACCGTGTGGAGCAGGTGGGTGACATGATTGATCGACT CTTCGACACCTCCGCC |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 735 | 1 | 735 | Delete and frame-shift 306:T->C |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
MetIleProProGlnGluAlaSerAlaArgArgArgGluIleGluAspLysLeuLysGln
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
MetIleProProGlnGluAlaSerAlaArgArgArgGluIleGluAspLysLeuLysGln
ATGATCCCCCCGCAAGAGGCGTCCGCCCGGCGGCGGGAGATCGAGGACAAGCTGAAGCAG
>>>> Target Intron 1 >>>> GluGluGluThrLeuSerPheIleArgAspS
174 bp |||||||||||||||||||||||||||||||
++ ++GluGluGluThrLeuSerPheIleArgAspS
gt agGAGGAGGAGACGCTGTCCTTCATCCGAGACA
erLeuGluLysSerAspGlnLeuThrLysAsnMet >>>> Target Intron 2 >>
||||||||||||||||||||||||||||||||||| 1098 bp
erLeuGluLysSerAspGlnLeuThrLysAsnMet++
GCCTGGAGAAGAGCGACCAGCTCACCAAGAACATGgt
>> ValSerIleLeuSerSerPheGluSerArgLeuMetLysLeuGluAsnSerIleIl
||||||||||||||||||||||||||||||||||||||||||||||||||||||||
++ValSerIleLeuSerSerPheGluSerArgLeuMetLysLeuGluAsnSerIleIl
agGTGTCTATCCTGTCGTCCTTTGAGAGCCGCCTCATGAAGCTGGAGAACTCCATCAT
eProValHisLysGlnThrGluAsnLeuGlnArgLeuGlnGluAsnValGluLysThrLe
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
eProValHisLysGlnThrGluAsnLeuGlnArgLeuGlnGluAsnValGluLysThrLe
CCCTGTGCACAAGCAGACAGAGAACCTGCAGCGGCTGCAGGAGAATGTAGAGAAGACACT
uSerCysLeuAspHisValIleSerTyrTyrHisValAlaSerAspThrGluLysIleIl
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
uSerCysLeuAspHisValIleSerTyrTyrHisValAlaSerAspThrGluLysIleIl
GTCCTGCCTAGACCATGTCATCAGCTACTACCACGTGGCCAGCGACACTGAGAAGATCAT
eArgGlu{Gl} >>>> Target Intron 3 >>>> {y}ProThrGlyArgLeuGl
|||||||{||} 200 bp {|}|||||||||||||||||
eArgGlu{Gl}++ ++{y}ProThrGlyArgLeuGl
CAGGGAG{GG}gt ag{C}CCCACAGGTAGGCTGGA
uGluTyrLeuGlySerMetAlaLysIleGlnLysAlaValGluTyrPheGlnAspAsnSe
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
uGluTyrLeuGlySerMetAlaLysIleGlnLysAlaValGluTyrPheGlnAspAsnSe
AGAGTACCTGGGGAGCATGGCCAAGATCCAGAAGGCTGTGGAATATTTCCAGGACAATAG
rProAspSerProGluLeuAsnLysVal >>>> Target Intron 4 >>>> Lys
|||||||||||||||||||||||||||| 5765 bp |||
rProAspSerProGluLeuAsnLysVal++ ++Lys
CCCAGATAGTCCAGAGCTCAACAAAGTGgt agAAG
LeuLeuPheGluArgGlyLysGluAlaLeuGluSerGluPheArgSerLeuMetThrArg
|||||||||||||||||||||||| |||||||||||||||||||||||||||||||||
LeuLeuPheGluArgGlyLysGluSerLeuGluSerGluPheArgSerLeuMetThrArg
CTGCTGTTTGAGCGGGGAAAGGAGTCTCTGGAGTCCGAGTTCCGCAGCCTGATGACCCGG
HisSerLysValValSerProValLeuIleLeuAspLeuIleSerGlyAspAspAspLeu
|||||||||||||||||||||||||||||||||||||||||||||||||||||| |||
HisSerLysValValSerProValLeuIleLeuAspLeuIleSerGlyAspAspGluLeu
CACAGTAAGGTCGTCTCCCCTGTGCTCATCCTGGATCTGATCAGTGGTGATGACGAGCTG
GluAlaGlnGluAspValThrLeuGluHisLeuProGluSerValLeuGlnAspValIle
||||||||| |||||||||||||||||||||||||||||||||||||||
AspValSerGluAspValValLeuGluHisLeuProGluSerValLeuGlnAspValIle
GACGTCTCGGAGGACGTGGTCCTGGAGCACCTGCCCGAGAGCGTGCTGCAGGATGTGATC
ArgIleSerArgTrpLeuValGluTyrGlyArgAsnGln{A} >>>> Target Intr
|||||||||||||||||||||||||||||| ||||||{|} 1769 bp
ArgIleSerArgTrpLeuValGluTyrGlyHisAsnGln{A}++
CGCATCTCCCGCTGGCTGGTGGAATACGGCCACAACCAA{G}gt
on 5 >>>> {sp}PheMetAsnValTyrTyrGlnIleArgSerSerGlnLeuAspArg
{||}|||||||||||||||||||||||||||||||||||||||||||||
++{sp}PheMetAsnValTyrTyrGlnIleArgSerSerGlnLeuAspArg
ag{AC}TTCATGAATGTCTACTACCAGATTCGCTCCAGCCAGCTGGACCGC
SerIleLysGlyLeuLysGluHisPheHisLysSerSerSerSerSerGlyValProTyr
||||||||||||||||||||||||||| ||| ||||||||||||||||||||||||
SerIleLysGlyLeuLysGluHisPheArgLysCysSerSerSerSerGlyValProTyr
TCCATCAAGGGCCTGAAGGAGCATTTTCGGAAATGCAGTTCTTCTTCTGGGGTTCCCTAC
SerProAlaIleProAsnLysArgLysAspThrProThrLysLysProValLysArgPro
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
SerProAlaIleProAsnLysArgLysAspThrProThrLysLysProValLysArgPro
TCCCCTGCCATCCCCAACAAGAGGAAAGACACACCTACCAAGAAGCCAGTCAAGCGGCCA
{G} >>>> Target Intron 6 >>>> {ly}ThrIleArgLysAlaGlnAsnLeu
{|} 3015 bp {||}||||||||||||||||||||||||
{G}++ ++{ly}ThrIleArgLysAlaGlnAsnLeu
{G}gt ag{GG}ACGATCCGTAAGGCTCAGAACCTT
LeuLysGlnTyrSerGlnHisGlyLeuAspGlyLysLysGlyGlySerAsnLeuIlePro
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
LeuLysGlnTyrSerGlnHisGlyLeuAspGlyLysLysGlyGlySerAsnLeuIlePro
CTGAAACAGTATTCCCAGCATGGTCTAGATGGGAAAAAGGGGGGCTCTAACCTCATTCCT
LeuGluGly >>>> Target Intron 7 >>>> LeuLeuProCysThrProArgG
||||||||| 760 bp ||||||||| ||| |
LeuGluGly --LeuLeuProVal---ProLysG
CTGGAAGGTaa ggCTTCTTCCCGTTC##CCCAAGG
lyGlyLeuProGlyProTrpIleAsnAlaAlaCysValCysAlaAlaAspIleSerProG
|| |||||||||||||||||||||||||||||||||||||||||||||||| |
lyGlnProProGlyProTrpIleAsnAlaAlaCysValCysAlaAlaAspIleSerLeuG
GGCAGCCGCCTGGCCCCTGGATAAACGCTGCTTGTGTTTGTGCGGCTGACATCTCGCTAG
lyHisGluHisAspPheArgValLysHisLeuSerGluAlaLeuAsnAspLysHisGlyP
|||||||||||||||||||||||||||||||| |||||||||||||||||||||
lyHisGluHisAspPheArgValLysHisLeuProGluAlaLeuAsnAspLysHisArgL
GTCACGAGCATGATTTCCGAGTTAAGCACCTGCCCGAGGCCCTGAACGACAAGCACAGGC
roLeuAla{G} >>>> Target Intron 8 >>>> {ly}ArgAspAspMetLeuA
||||||{|} 957 bp {||}||||||||| ||||
euLeuAla{G}++ ++{ly}ArgAspAspThrLeuA
TGCTGGCC{G}gt ag{GG}AGAGACGACACGCTGG
spValGluThrAspAlaTyrIleHisCysValSerAlaPheValLysLeuAlaGlnSerG
|||||||||||||||||||||||||||||||||||||||||||| |||||||||||||
spValGluThrAspAlaTyrIleHisCysValSerAlaPheValArgLeuAlaGlnSerG
ACGTGGAGACCGACGCCTACATCCACTGCGTCAGTGCCTTCGTCAGGCTGGCCCAGAGCG
luTyrGlnLeuLeuAlaAspIleIleProGluHisHisGlnLysLysThrPheAspSerL
|||||||||||||| ||| |||||||||||||||||||||||||||||||||||||
luTyrGlnLeuLeuThrAspValIleProGluHisHisGlnLysLysThrPheAspSerL
AGTACCAGCTGCTGACCGACGTCATCCCTGAGCACCACCAGAAGAAAACCTTCGACTCCT
euIleGln >>>> Target Intron 9 >>>> AspAlaLeuAspGlyLeuMetLe
|||||||| 248 bp |||||||||||||||||| ||
euIleGln++ ++AspAlaLeuAspGlyLeuIleLe
TGATACAGgt agGACGCGCTGGACGGGCTGATCCT
uGluGlyGluAsnIleValSerAlaAlaArgLysAlaIleValArgHisAspPheSerTh
||||||| ||||||||| |||||||||||||||||| |||||||||||| ||
uGluGlyAspAsnIleValCysAlaAlaArgLysAlaIleMetArgHisAspPheProTh
GGAGGGGGACAACATCGTGTGTGCCGCCCGCAAGGCCATCATGCGGCACGACTTCCCCAC
rValLeuThrValPheProIleLeuArgHisLeuLysGlnThrLysProGluPheAspGl
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
rValLeuThrValPheProIleLeuArgHisLeuLysGlnThrLysProGluPheAspGl
GGTGCTCACCGTCTTCCCCATCCTGCGGCACCTCAAGCAGACCAAGCCCGAGTTCGACCA
nValLeuGln >>>> Target Intron 10 >>>> GlyThrAlaAlaSerThrLy
|||||||||| 617 bp ||||||||||||||||||||
nValLeuGln++ ++GlyThrAlaAlaSerThrLy
GGTGCTCCAGgt agGGCACGGCCGCCAGCACCAA
sAsnLysLeuProGlyLeuIleThrSerMetGluThrIleGlyAlaLysAlaLeuGluAs
||||||||||||| ||||||||||||||||||||||||||||||||||||||||||||
sAsnLysLeuProSerLeuIleThrSerMetGluThrIleGlyAlaLysAlaLeuGluAs
GAACAAACTGCCCAGCCTCATCACCTCCATGGAGACCATCGGGGCGAAAGCGCTGGAGGA
pPheAlaAspAsnIleLys >>>> Target Intron 11 >>>> AsnAspProAs
||||||||||||||||||| 282 bp |||||||||||
pPheAlaAspAsnIleLys++ ++AsnAspProAs
CTTTGCCGACAACATCAAGgt agAATGACCCGGA
pLysGluTyrAsnMetProLysAspGlyThrValHisGluLeuThrSerAsn >>>> T
||||||||||||||||||||||||||||||||||||||||||||||||||||
pLysGluTyrAsnMetProLysAspGlyThrValHisGluLeuThrSerAsn++
CAAGGAGTACAACATGCCCAAGGATGGCACCGTGCACGAGCTCACAAGCAACgt
arget Intron 12 >>>> AlaIleLeuPheLeuGlnGlnLeuLeuAspPheGlnGl
305 bp ||||||||||||||||||||||||||||||||||||||
++AlaIleLeuPheLeuGlnGlnLeuLeuAspPheGlnGl
agGCCATCCTCTTCCTGCAGCAGCTTCTGGACTTCCAGGA
uThrAlaGlyAlaMetLeuAlaSerGln{G} >>>> Target Intron 13 >>>>
||||||||||||||||||||||||||||{|} 1411 bp
uThrAlaGlyAlaMetLeuAlaSerGln{G}++ +
GACAGCAGGTGCCATGCTGGCCTCCCAA{G}gt a
{lu}ThrSerSerSerAlaThrSerTyrSerSerGluPheSerLysArgLeuLeuSerT
{||}||||||||||||||||||||| |||||| ||| |||||||||||||
+{lu}ThrSerSerSerAlaThrSerHisSerSerValValSerArgArgLeuLeuSerT
g{AG}ACCAGCTCCTCGGCCACCAGCCACAGCTCCGTGGTCAGCAGGCGCCTGCTGAGCA
hrTyrIle{C} >>>> Target Intron 14 >>>> {ys}LysValLeuGlyAsn
||||||||{|} 256 bp {||}|||||||||||||||
hrTyrIle{C}++ ++{ys}LysValLeuGlyAsn
CCTACATC{T}gt ag{GT}AAAGTCCTAGGCAAC
LeuGlnLeuAsnLeuLeuSerLysSerLysValTyrGluAspProAlaLeuSerAlaIle
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
LeuGlnLeuAsnLeuLeuSerLysSerLysValTyrGluAspProAlaLeuSerAlaIle
CTGCAGCTGAACTTGCTGAGCAAGTCCAAGGTGTACGAGGACCCCGCTCTGAGCGCCATC
PheLeuHisAsnAsnTyrAsnTyrIleLeuLysSerLeuGlu{Ly} >>>> Target
||||||||||||||||||||||||||||||||||||||||||{||} 18
PheLeuHisAsnAsnTyrAsnTyrIleLeuLysSerLeuGlu{Ly}++
TTCCTGCACAACAACTACAACTACATCCTCAAGTCCCTGGAG{AA}gt
Intron 15 >>>> {s}SerGluLeuIleGlnLeuValAlaValThrGlnLysThrAl
0 bp {|}|||||||||||||||||||||||||||||||||||||||||
++{s}SerGluLeuIleGlnLeuValAlaValThrGlnLysThrAl
ag{G}TCTGAGCTGATCCAGCTGGTGGCTGTGACCCAGAAGACAGC
aGluArgSerTyrArgGluHisIleGluGlnGlnIleGlnThrTyrGlnArg{Se} >>
||||||||||||||||||||||||||||||||||||||||||||||||||||{||}
aGluArgSerTyrArgGluHisIleGluGlnGlnIleGlnThrTyrGlnArg{Se}++
GGAGCGCTCCTACCGGGAGCACATTGAGCAGCAGATCCAGACCTACCAGCGC{AG}gt
>> Target Intron 16 >>>> {r}TrpLeuLysValThrAspTyrIleAlaGluL
499 bp {|}||| |||||||||||||||||| ||||
++{r}TrpValLysValThrAspTyrIleThrGluL
ag{C}TGGGTGAAGGTGACGGACTACATCACAGAGA
ysAsnLeuProValPheGlnProGlyValLys >>>> Target Intron 17 >>>>
|||||||||||||||||||||||||||||||| 212 bp
ysAsnLeuProValPheGlnProGlyValLys++
AGAACCTGCCTGTGTTCCAGCCTGGGGTCAAGgt
LeuArgAspLysGluArgGlnIleIleLysGluArgPheLys >>>> Target In
||||||||||||||||||||| |||||||||||||||||| 104
++LeuArgAspLysGluArgGlnMetIleLysGluArgPheLys++
agCTCCGGGACAAGGAACGGCAGATGATCAAGGAGCGTTTTAAGgt
tron 18 >>>> GlyPheAsnAspGlyLeuGluGluLeuCysLysIleGlnLysAlaT
bp ||||||||||||||||||||||||||||||||||||||||||||||
++GlyPheAsnAspGlyLeuGluGluLeuCysLysIleGlnLysAlaT
agGGTTTCAATGATGGTCTCGAAGAATTGTGCAAGATCCAGAAAGCCT
rpAlaIleProAspThrGluGlnArgAspArgIleArgGlnAlaGlnLysThrIleValL
||||||||||||||||||||||||||||| |||||||||||||||||| ||||
rpAlaIleProAspThrGluGlnArgAspLysIleArgGlnAlaGlnLysAsnValValL
GGGCTATTCCCGACACGGAGCAGAGGGACAAGATTCGCCAGGCTCAGAAAAACGTTGTCA
ysGluThrTyrGlyAlaPheLeuGln{Ly} >>>> Target Intron 19 >>>>
||||||||||||||||||||||| { } 228 bp
ysGluThrTyrGlyAlaPheLeuHis{Ar}++ ++
AGGAGACCTACGGGGCCTTCCTGCAC{AG}gt ag
{s}PheGlySerValProPheThrLysAsnProGluLysTyrIleLysTyrGlyValGlu
{ } ||| ||||||||||||||||||||||||||||||||||||||| ||||||
{g}TyrGlyGlyValProPheThrLysAsnProGluLysTyrIleLysTyrArgValGlu
{G}TATGGTGGCGTGCCCTTCACCAAGAACCCCGAGAAGTACATCAAGTACCGTGTGGAG
GlnValGlyAspMetIleAspArgLeuPheAspThrSerAla
||||||||||||||||||||||||||||||||||||||||||
GlnValGlyAspMetIleAspArgLeuPheAspThrSerAla
CAGGTGGGTGACATGATTGATCGACTCTTCGACACCTCCGCC
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