| Basic information |
| Official Symbol | EPHB2 |
| Description | EPH receptor B2 |
| Other Aliases | CAPB, DRT, EK5, EPHT3, ERK, Hek5, PCBC, Tyro5 |
| Other Description | EPH-like kinase 5; developmentally-regulated Eph-related tyrosine kinase; elk-related tyrosine kinase; eph tyrosine kinase 3; ephrin type-B receptor 2; protein-tyrosine kinase HEK5; renal carcinoma antigen NY-REN-47; tyrosine-protein kinase TYRO5; tyrosine-protein kinase receptor EPH-3 |
| Mutation type | Insert and frame-shift 1001-1002:R-C^CG, Insert and frame-shift 1037-1038:G-I^T |
| Location | Scaffold000146_1:1075844 929083 - |
| Wiki | Wikipedia GeneCard |
| Sequence |
| EPHB2 |
CTCTCTGCTCTCCCCACAGAGACGCTGATGGACTCCACTACGGCGACAGC CGAGCTGGGCTGGATGGTGCATCCTCCGTCGGGGTGGGAAGAGGTGAGCG GCTACGACGAGAACATGAACACGATCCGCACGTACCAGGTGTGCAACGTG TTTGAGTCGAGCCAGAACAACTGGCTGCGGACCAAGTTCATCCGGCGCCG CGGCGCCCACCGCGTCCACGTGGAGATGAAGTTCTCGGTGCGCGACTGCA GCAGCATCCCCAGTGTGCCTGGATCCTGCAAGGAGACCTTCAACCTCTAC TACTATGAGGCCGACTTTGACTCGGCCACCAAGACCTTCCCCAACTGGAT GGAGAACCCGTGGGTGAAGGTGGACACCATCGCGGCCGACGAGAGCTTCT CCCAGGTGGACCTGGGCGGCCGGGTCATGAAGATCAACACCGAGGTGCGC AGCTTTGGACCCGTGTCCCGCAATGGCTTCTACCTGGCCTTCCAGGATTA TGGCGGCTGCATGTCCCTCATCGCTGTGCGTGTCTTCTACCGCAAGTGCC CCCGCGTCATCCAGAATGGCGCCATCTTTCAGGAGACGCTGTCGGGGGCC GAGAGCACTTCGCTGGTGGCCGCCCGGGGCAGCTGCATCTCCAATGCTGA GGAGGTGGACGTGCCCATCAAGCTCTACTGTAACGGCGACGGCGAGTGGN NNNNNNNNNGGGGGCGCTGCCTGTGCAAAGCCGGCTTTGAGGCCGTGGAG AACGGCACCGTCTGCCGAGGTTGTCCATCTGGAACTTTCAAGGCCAACCA GGGGGACGAGGCCTGCACCCACTGTCCCATCAACAGCCGGACCACCTCAG AAGGGGCCACCAACTGTGTCTGCCGCAATGGCTACTACAGAGCGGACCTG GACCCCCTGGACATGCCTTGCACGACCATCCCCTCTGCACCTCAGGCTGT GATCTCCAGCGTCAACGAGACGTCCCTCATGTTGGAGTGGACCCCTCCCC GCGACTCCGGAGGCCGGGAGGATCTGGTCTACAACATCATCTGCAAGAGC TGCGGCTCGGGCAGGGGCGCCTGCACCCGCTGCGGGGACAACGTGCAGTA CGCGCCACGCCAGCTGGGCCTGACCGAGCCGCGCATCTACATCAGCGACC TGCTGGCCCACACCCAGTACACCTTCGAGATCCAGGCCGTGAACGGCGTG ACTGACCAGAGCCCCTTCTCGCCGCAGTTCGCCTCCGTGAACATCACCAC CAACCAAGCAGCTCCGTCAGCTGTGTCCATCATGCACCAGGTGAGCCGCA CTGTGGACAGCATCACCCTGTCGTGGTCCCAGCCGGACCAGCCAAACGGT GTGATTCTGGACTACGAGCTGCAGTACTATGAGAAGGAGCTCAGTGAGTA CAACGCCACAGCCATAAAAAGCCCCACCAACACGGCCACTGTGCAGGGCC TCAAAGCCGGCGCCATCTATGTCTTCCAGGTGCGGGCTCGCACCGTGGCC GGCTATGGGCGCTACAGCGGCAAGATGTACTTCCAGACCATGACGGAAGC GGAGCCCCAGCCAAGCTCCCAGGAGACCCTGCCACTCATCGTCGGCTCCT CGGCCGCCGGCCTGGTCTTCCTCATCGCTGTGGTTGTCATCGCCATCGTG TGTAACAGACGGGGCTTTGAGCGTGCCGACTCGGAGTACACGGACAAGCT GCAGCACTACACCAGCGGCCACATGACCCCAGGCATGAAGATCTACATCG ACCCTTTCACCTACGAGGACCCCAATGAGGCCGTGCGGGAATTTGCCAAG GAAATTGACATCTCCTGTGTCAAAATTGAGCAGGTGATCGGAGCAGGGGA GTTTGGTGAGGTCTGCAGTGGCCACCTGAAGCTTCCAGGCAAGAGAGAAA TCTTCGTGGCCATCAAGACGCTCAAGTCAGGCTACACCGAGAAGCAGCGC CGGGACTTCCTGAGTGAGGCCTCCATTATGGGCCAGTTCGACCACCCCAA CGTCATCCACCTGGAGGGCGTTGTCACCAAGAGCACACCTGTGATGATCA TCACCGAGTTCATGGAGAATGGCTCCCTGGACTCCTTCCTCCGGCAAAAT GACGGGCAGTTCACAGTCATCCAGCTGGTGGGCATGCTGCGTGGCATCGC GGCCGGCATGAAGTACCTGGCGGACATGAACTACGTGCACCGCGACCTAG CCGCCCGCAACATCCTTGTCAACAGCAACCTGGTCTGCAAGGTGTCTGAC TTCGGGCTCTCACGCTTCCTGGAGGACGACACCTCAGACCCCACCTACAC CAGTGCCCTGGGTGGGAAGATCCCCATCCGCTGGACGGCCCCAGAAGCCA TCCAGTACCGGAAGTTCACCTCGGCCAGTGACGTGTGGAGCTACGGTATC GTCATGTGGGAAGTGATGTCCTATGGGGAGCGGCCCTACTGGGACATGAC CAACCAGGACGTAATCAACGCCATCGAGCAGGACTATCGGCTGCCGCCGC CCATGGACTGCCCGAGCGCCCTGCACCAGCTCATGCTGGACTGCTGGCAG AAGGACCGCAACCACCGGCCCAAGTTCGGCCAGATCGTCAACACGCTGGA CAAGATGATCCGCAACCCCAACAGCCTCAAAGCGATGGCGCCCCTCTCCT CCGGAATCAACCTGCCCCTGCTGGATCGCACGGTCCCCGACTACACCAGC TTTCACACGGTGGACGAGTGGCTGGAGGCCATCAAGATGGGGCAGTACAA GGAGAGCTTCGCCAGCGCCGGCTTCACCTCCTTCGATGTCGTGTCCCAGA TGATGATGGAGGACATTCTCCGGGTTGGGGTCACCTTGGCTGGCCACCAG AAGAAAATCCTGAACAGTATCCAGGTGATGCGGGCACAGATGAACCAGAT CCAGTCTGTGGAGGGCCAGCCACCTGCCAGGAGGCCACGGGCGACAGGAA GGACCGAGCAGCTGCAGCCACGGGATGTGACCAGGAACACACGCAACTCC AACGATGGAAAAAGGGAATGGGGAACAAAGAAAACCGATCCTGGGAGGGG GCGGGAAAGACAGGACATTTTTAAAGAGGATTCTCAAAAGGAAAGCGATG ACTGT |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 1055 | 15 | 1051 | Insert and frame-shift 1001-1002:R-C^CG, Insert and frame-shift 1037-1038:G-I^T |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
LeuLeuAlaAlaValGluGluThrLeuMetAspSerThrThrAlaThrAlaGluLeuG
||| ||| ||||||||||||||||||||||||||||||||||||||||
LeuSerAlaLeuProThrGluThrLeuMetAspSerThrThrAlaThrAlaGluLeuG
CTCTCTGCTCTCCCCACAGAGACGCTGATGGACTCCACTACGGCGACAGCCGAGCTGG
lyTrpMetValHisProProSerGly >>>> Target Intron 1 >>>> Trp
|||||||||||||||||||||||||| 2780 bp |||
lyTrpMetValHisProProSerGly++ ++Trp
GCTGGATGGTGCATCCTCCGTCGGGGgt agTGG
GluGluValSerGlyTyrAspGluAsnMetAsnThrIleArgThrTyrGlnValCysA
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GluGluValSerGlyTyrAspGluAsnMetAsnThrIleArgThrTyrGlnValCysA
GAAGAGGTGAGCGGCTACGACGAGAACATGAACACGATCCGCACGTACCAGGTGTGCA
snValPheGluSerSerGlnAsnAsnTrpLeuArgThrLysPheIleArgArgArgGl
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
snValPheGluSerSerGlnAsnAsnTrpLeuArgThrLysPheIleArgArgArgGl
ACGTGTTTGAGTCGAGCCAGAACAACTGGCTGCGGACCAAGTTCATCCGGCGCCGCGG
yAlaHisArgIleHisValGluMetLysPheSerValArgAspCysSerSerIlePro
|||||||||| |||||||||||||||||||||||||||||||||||||||||||||
yAlaHisArgValHisValGluMetLysPheSerValArgAspCysSerSerIlePro
CGCCCACCGCGTCCACGTGGAGATGAAGTTCTCGGTGCGCGACTGCAGCAGCATCCCC
SerValProGlySerCysLysGluThrPheAsnLeuTyrTyrTyrGluAlaAspPheA
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
SerValProGlySerCysLysGluThrPheAsnLeuTyrTyrTyrGluAlaAspPheA
AGTGTGCCTGGATCCTGCAAGGAGACCTTCAACCTCTACTACTATGAGGCCGACTTTG
spSerAlaThrLysThrPheProAsnTrpMetGluAsnProTrpValLysValAspTh
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
spSerAlaThrLysThrPheProAsnTrpMetGluAsnProTrpValLysValAspTh
ACTCGGCCACCAAGACCTTCCCCAACTGGATGGAGAACCCGTGGGTGAAGGTGGACAC
rIleAlaAlaAspGluSerPheSerGlnValAspLeuGlyGlyArgValMetLysIle
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
rIleAlaAlaAspGluSerPheSerGlnValAspLeuGlyGlyArgValMetLysIle
CATCGCGGCCGACGAGAGCTTCTCCCAGGTGGACCTGGGCGGCCGGGTCATGAAGATC
AsnThrGluValArgSerPheGlyProValSerArgSerGlyPheTyrLeuAlaPheG
|||||||||||||||||||||||||||||||||||| |||||||||||||||||||
AsnThrGluValArgSerPheGlyProValSerArgAsnGlyPheTyrLeuAlaPheG
AACACCGAGGTGCGCAGCTTTGGACCCGTGTCCCGCAATGGCTTCTACCTGGCCTTCC
lnAspTyrGlyGlyCysMetSerLeuIleAlaValArgValPheTyrArgLysCysPr
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
lnAspTyrGlyGlyCysMetSerLeuIleAlaValArgValPheTyrArgLysCysPr
AGGATTATGGCGGCTGCATGTCCCTCATCGCTGTGCGTGTCTTCTACCGCAAGTGCCC
oArgIleIleGlnAsnGlyAlaIlePheGlnGluThrLeuSerGlyAlaGluSerThr
|||| |||||||||||||||||||||||||||||||||||||||||||||||||||
oArgValIleGlnAsnGlyAlaIlePheGlnGluThrLeuSerGlyAlaGluSerThr
CCGCGTCATCCAGAATGGCGCCATCTTTCAGGAGACGCTGTCGGGGGCCGAGAGCACT
SerLeuValAlaAlaArgGlySerCysIleAlaAsnAlaGluGluValAspValProI
|||||||||||||||||||||||||||||| |||||||||||||||||||||||||
SerLeuValAlaAlaArgGlySerCysIleSerAsnAlaGluGluValAspValProI
TCGCTGGTGGCCGCCCGGGGCAGCTGCATCTCCAATGCTGAGGAGGTGGACGTGCCCA
leLysLeuTyrCysAsnGlyAspGlyGluTrpLeuValPro{I} >>>> Target
|||||||||||||||||||||||||||||||| { } 68
leLysLeuTyrCysAsnGlyAspGlyGluTrpUnkUnkUnk{U}--
TCAAGCTCTACTGTAACGGCGACGGCGAGTGGNNNNNNNNN{N}nn
Intron 2 >>>> {le}GlyArgCysMetCysLysAlaGlyPheGluAlaValGlu
6 bp { }||||||||| |||||||||||||||||||||||||||
-+{nk}GlyArgCysLeuCysLysAlaGlyPheGluAlaValGlu
ng{GG}GGGCGCTGCCTGTGCAAAGCCGGCTTTGAGGCCGTGGAG
AsnGlyThrValCysArg{G} >>>> Target Intron 3 >>>> {ly}CysP
||||||||||||||||||{|} 94249 bp {||}||||
AsnGlyThrValCysArg{G}++ ++{ly}CysP
AACGGCACCGTCTGCCGA{G}gt ag{GT}TGTC
roSerGlyThrPheLysAlaAsnGlnGlyAspGluAlaCysThrHisCysProIleAs
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
roSerGlyThrPheLysAlaAsnGlnGlyAspGluAlaCysThrHisCysProIleAs
CATCTGGAACTTTCAAGGCCAACCAGGGGGACGAGGCCTGCACCCACTGTCCCATCAA
nSerArgThrThrSerGluGlyAlaThrAsnCysValCysArgAsnGlyTyrTyrArg
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
nSerArgThrThrSerGluGlyAlaThrAsnCysValCysArgAsnGlyTyrTyrArg
CAGCCGGACCACCTCAGAAGGGGCCACCAACTGTGTCTGCCGCAATGGCTACTACAGA
AlaAspLeuAspProLeuAspMetProCysThr{T} >>>> Target Intron 4
|||||||||||||||||||||||||||||||||{|} 1011 bp
AlaAspLeuAspProLeuAspMetProCysThr{T}++
GCGGACCTGGACCCCCTGGACATGCCTTGCACG{A}gt
>>>> {hr}IleProSerAlaProGlnAlaValIleSerSerValAsnGluThrSe
{||}|||||||||||||||||||||||||||||||||||||||||||||||
++{hr}IleProSerAlaProGlnAlaValIleSerSerValAsnGluThrSe
ag{CC}ATCCCCTCTGCACCTCAGGCTGTGATCTCCAGCGTCAACGAGACGTC
rLeuMetLeuGluTrpThrProProArgAspSerGlyGlyArgGluAspLeuValTyr
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
rLeuMetLeuGluTrpThrProProArgAspSerGlyGlyArgGluAspLeuValTyr
CCTCATGTTGGAGTGGACCCCTCCCCGCGACTCCGGAGGCCGGGAGGATCTGGTCTAC
AsnIleIleCysLysSerCysGlySerGlyArgGlyAlaCysThrArgCysGlyAspA
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
AsnIleIleCysLysSerCysGlySerGlyArgGlyAlaCysThrArgCysGlyAspA
AACATCATCTGCAAGAGCTGCGGCTCGGGCAGGGGCGCCTGCACCCGCTGCGGGGACA
snValGlnTyrAlaProArgGlnLeuGlyLeuThrGluProArgIleTyrIleSerAs
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
snValGlnTyrAlaProArgGlnLeuGlyLeuThrGluProArgIleTyrIleSerAs
ACGTGCAGTACGCGCCACGCCAGCTGGGCCTGACCGAGCCGCGCATCTACATCAGCGA
pLeuLeuAlaHisThrGlnTyrThrPheGluIleGlnAlaValAsnGlyValThrAsp
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
pLeuLeuAlaHisThrGlnTyrThrPheGluIleGlnAlaValAsnGlyValThrAsp
CCTGCTGGCCCACACCCAGTACACCTTCGAGATCCAGGCCGTGAACGGCGTGACTGAC
GlnSerProPheSerProGlnPheAlaSerValAsnIleThrThrAsnGlnAla{A}
||||||||||||||||||||||||||||||||||||||||||||||||||||||{|}
GlnSerProPheSerProGlnPheAlaSerValAsnIleThrThrAsnGlnAla{A}+
CAGAGCCCCTTCTCGCCGCAGTTCGCCTCCGTGAACATCACCACCAACCAAGCA{G}g
>>>> Target Intron 5 >>>> {la}ProSerAlaValSerIleMetHisGl
18813 bp {||}||||||||||||||||||||||||||
+ ++{la}ProSerAlaValSerIleMetHisGl
t ag{CT}CCGTCAGCTGTGTCCATCATGCACCA
nValSerArgThrValAspSerIleThrLeuSerTrpSerGlnProAspGlnProAsn
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
nValSerArgThrValAspSerIleThrLeuSerTrpSerGlnProAspGlnProAsn
GGTGAGCCGCACTGTGGACAGCATCACCCTGTCGTGGTCCCAGCCGGACCAGCCAAAC
GlyValIleLeuAspTyrGluLeuGlnTyrTyrGluLys >>>> Target Intro
||||||||||||||||||||||||||||||||||||||| 8074 bp
GlyValIleLeuAspTyrGluLeuGlnTyrTyrGluLys++
GGTGTGATTCTGGACTACGAGCTGCAGTACTATGAGAAGgt
n 6 >>>> GluLeuSerGluTyrAsnAlaThrAlaIleLysSerProThrAsnThr
||||||||||||||||||||||||||||||||||||||||||||||||
++GluLeuSerGluTyrAsnAlaThrAlaIleLysSerProThrAsnThr
agGAGCTCAGTGAGTACAACGCCACAGCCATAAAAAGCCCCACCAACACG
ValThrValGlnGlyLeuLysAlaGlyAlaIleTyrValPheGlnValArgAlaArgT
|||||||||||||||||||||||||||||||||||||||||||||||||||||||
AlaThrValGlnGlyLeuLysAlaGlyAlaIleTyrValPheGlnValArgAlaArgT
GCCACTGTGCAGGGCCTCAAAGCCGGCGCCATCTATGTCTTCCAGGTGCGGGCTCGCA
hrValAlaGlyTyrGlyArgTyrSerGlyLysMetTyrPheGlnThrMetThrGlu{A
||||||||||||||||||||||||||||||||||||||||||||||||||||||||{|
hrValAlaGlyTyrGlyArgTyrSerGlyLysMetTyrPheGlnThrMetThrGlu{A
CCGTGGCCGGCTATGGGCGCTACAGCGGCAAGATGTACTTCCAGACCATGACGGAA{G
} >>>> Target Intron 7 >>>> {la}GluTyrGlnThrSerIleGlnGlu
} 1978 bp {||}||| ||| ||| ||||||
}++ ++{la}GluProGlnProSerSerGlnGlu
}gt ag{CG}GAGCCCCAGCCAAGCTCCCAGGAG
LysLeuProLeuIleIleGlySerSerAlaAlaGlyLeuValPheLeuIleAlaValV
|||||||||||| ||||||||||||||||||||||||||||||||||||||||
ThrLeuProLeuIleValGlySerSerAlaAlaGlyLeuValPheLeuIleAlaValV
ACCCTGCCACTCATCGTCGGCTCCTCGGCCGCCGGCCTGGTCTTCCTCATCGCTGTGG
alValIleAlaIleValCysAsn{Ar} >>>> Target Intron 8 >>>> {g
|||||||||||||||||||||||{||} 756 bp {|
alValIleAlaIleValCysAsn{Ar}++ ++{g
TTGTCATCGCCATCGTGTGTAAC{AG}gt ag{A
}ArgGlyPheGluArgAlaAspSerGluTyrThrAspLysLeuGlnHisTyrThrSer
}|||||||||||||||||||||||||||||||||||||||||||||||||||||||||
}ArgGlyPheGluArgAlaAspSerGluTyrThrAspLysLeuGlnHisTyrThrSer
}CGGGGCTTTGAGCGTGCCGACTCGGAGTACACGGACAAGCTGCAGCACTACACCAGC
GlyHis{M} >>>> Target Intron 9 >>>> {et}ThrProGlyMetLysI
||||||{|} 9024 bp {||}||||||||||||||||
GlyHis{M}++ ++{et}ThrProGlyMetLysI
GGCCAC{A}gt ag{TG}ACCCCAGGCATGAAGA
leTyrIleAspProPheThrTyrGluAspProAsnGluAlaValArgGluPheAlaLy
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
leTyrIleAspProPheThrTyrGluAspProAsnGluAlaValArgGluPheAlaLy
TCTACATCGACCCTTTCACCTACGAGGACCCCAATGAGGCCGTGCGGGAATTTGCCAA
sGluIleAspIleSerCysValLysIleGluGlnValIleGlyAla{G} >>>> Ta
||||||||||||||||||||||||||||||||||||||||||||||{|}
sGluIleAspIleSerCysValLysIleGluGlnValIleGlyAla{G}++
GGAAATTGACATCTCCTGTGTCAAAATTGAGCAGGTGATCGGAGCA{G}gt
rget Intron 10 >>>> {ly}GluPheGlyGluValCysSerGlyHisLeuLys
578 bp {||}|||||||||||||||||||||||||||||||||
++{ly}GluPheGlyGluValCysSerGlyHisLeuLys
ag{GG}GAGTTTGGTGAGGTCTGCAGTGGCCACCTGAAG
LeuProGlyLysArgGluIlePheValAlaIleLysThrLeuLysSerGlyTyrThrG
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
LeuProGlyLysArgGluIlePheValAlaIleLysThrLeuLysSerGlyTyrThrG
CTTCCAGGCAAGAGAGAAATCTTCGTGGCCATCAAGACGCTCAAGTCAGGCTACACCG
luLysGlnArgArgAspPheLeuSerGluAlaSerIleMetGlyGlnPheAspHisPr
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
luLysGlnArgArgAspPheLeuSerGluAlaSerIleMetGlyGlnPheAspHisPr
AGAAGCAGCGCCGGGACTTCCTGAGTGAGGCCTCCATTATGGGCCAGTTCGACCACCC
oAsnValIleHisLeuGluGlyValValThrLysSerThrProValMetIleIleThr
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
oAsnValIleHisLeuGluGlyValValThrLysSerThrProValMetIleIleThr
CAACGTCATCCACCTGGAGGGCGTTGTCACCAAGAGCACACCTGTGATGATCATCACC
GluPheMetGluAsnGlySerLeuAspSerPheLeuArg >>>> Target Intro
||||||||||||||||||||||||||||||||||||||| 1346 bp
GluPheMetGluAsnGlySerLeuAspSerPheLeuArg++
GAGTTCATGGAGAATGGCTCCCTGGACTCCTTCCTCCGGgt
n 11 >>>> GlnAsnAspGlyGlnPheThrValIleGlnLeuValGlyMetLeuAr
|||||||||||||||||||||||||||||||||||||||||||||||
++GlnAsnAspGlyGlnPheThrValIleGlnLeuValGlyMetLeuAr
agCAAAATGACGGGCAGTTCACAGTCATCCAGCTGGTGGGCATGCTGCG
gGlyIleAlaAlaGlyMetLysTyrLeuAlaAspMetAsnTyrValHisArgAspLeu
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
gGlyIleAlaAlaGlyMetLysTyrLeuAlaAspMetAsnTyrValHisArgAspLeu
TGGCATCGCGGCCGGCATGAAGTACCTGGCGGACATGAACTACGTGCACCGCGACCTA
AlaAlaArgAsnIleLeuValAsnSerAsnLeuValCysLysValSerAspPheGlyL
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
AlaAlaArgAsnIleLeuValAsnSerAsnLeuValCysLysValSerAspPheGlyL
GCCGCCCGCAACATCCTTGTCAACAGCAACCTGGTCTGCAAGGTGTCTGACTTCGGGC
euSerArgPheLeuGluAspAspThrSerAspProThrTyrThrSerAlaLeu >>>
|||||||||||||||||||||||||||||||||||||||||||||||||||||
euSerArgPheLeuGluAspAspThrSerAspProThrTyrThrSerAlaLeu++
TCTCACGCTTCCTGGAGGACGACACCTCAGACCCCACCTACACCAGTGCCCTGgt
> Target Intron 12 >>>> GlyGlyLysIleProIleArgTrpThrAlaPro
812 bp |||||||||||||||||||||||||||||||||
++GlyGlyLysIleProIleArgTrpThrAlaPro
agGGTGGGAAGATCCCCATCCGCTGGACGGCCCCA
GluAlaIleGlnTyrArgLysPheThrSerAlaSerAspValTrpSerTyrGlyIleV
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GluAlaIleGlnTyrArgLysPheThrSerAlaSerAspValTrpSerTyrGlyIleV
GAAGCCATCCAGTACCGGAAGTTCACCTCGGCCAGTGACGTGTGGAGCTACGGTATCG
alMetTrpGluValMetSerTyrGlyGluArgProTyrTrpAspMetThrAsnGlnAs
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
alMetTrpGluValMetSerTyrGlyGluArgProTyrTrpAspMetThrAsnGlnAs
TCATGTGGGAAGTGATGTCCTATGGGGAGCGGCCCTACTGGGACATGACCAACCAGGA
p >>>> Target Intron 13 >>>> ValIleAsnAlaIleGluGlnAspTyr
| 1039 bp |||||||||||||||||||||||||||
p++ ++ValIleAsnAlaIleGluGlnAspTyr
Cgt agGTAATCAACGCCATCGAGCAGGACTAT
ArgLeuProProProMetAspCysProSerAlaLeuHisGlnLeuMetLeuAspCysT
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ArgLeuProProProMetAspCysProSerAlaLeuHisGlnLeuMetLeuAspCysT
CGGCTGCCGCCGCCCATGGACTGCCCGAGCGCCCTGCACCAGCTCATGCTGGACTGCT
rpGlnLysAspArgAsnHisArgProLysPheGlyGlnIleValAsnThrLeuAspLy
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
rpGlnLysAspArgAsnHisArgProLysPheGlyGlnIleValAsnThrLeuAspLy
GGCAGAAGGACCGCAACCACCGGCCCAAGTTCGGCCAGATCGTCAACACGCTGGACAA
sMetIleArgAsnProAsnSerLeuLysAlaMetAlaProLeuSerSer{Gl} >>>
|||||||||||||||||||||||||||||||||||||||||||||||||{||}
sMetIleArgAsnProAsnSerLeuLysAlaMetAlaProLeuSerSer{Gl}++
GATGATCCGCAACCCCAACAGCCTCAAAGCGATGGCGCCCCTCTCCTCC{GG}gt
> Target Intron 14 >>>> {y}IleAsnLeuProLeuLeuAspArgThrIle
1961 bp {|}|||||||||||||||||||||||||||
++{y}IleAsnLeuProLeuLeuAspArgThrVal
ag{A}ATCAACCTGCCCCTGCTGGATCGCACGGTC
ProAspTyrThrSerPheAsnThrValAspGluTrpLeuGluAlaIleLysMetGlyG
|||||||||||||||||| |||||||||||||||||||||||||||||||||||||
ProAspTyrThrSerPheHisThrValAspGluTrpLeuGluAlaIleLysMetGlyG
CCCGACTACACCAGCTTTCACACGGTGGACGAGTGGCTGGAGGCCATCAAGATGGGGC
lnTyrLysGluSerPheAlaAsnAlaGlyPheThrSerPheAspValValSerGlnMe
|||||||||||||||||||| |||||||||||||||||||||||||||||||||||
lnTyrLysGluSerPheAlaSerAlaGlyPheThrSerPheAspValValSerGlnMe
AGTACAAGGAGAGCTTCGCCAGCGCCGGCTTCACCTCCTTCGATGTCGTGTCCCAGAT
tMetMet{Gl} >>>> Target Intron 15 >>>> {u}AspIleLeuArgVa
|||||||{||} 461 bp {|}||||||||||||||
tMetMet{Gl}++ ++{u}AspIleLeuArgVa
GATGATG{GA}gt ag{G}GACATTCTCCGGGT
lGlyValThrLeuAlaGlyHisGlnLysLysIleLeuAsnSerIleGlnValMetArg
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
lGlyValThrLeuAlaGlyHisGlnLysLysIleLeuAsnSerIleGlnValMetArg
TGGGGTCACCTTGGCTGGCCACCAGAAGAAAATCCTGAACAGTATCCAGGTGATGCGG
AlaGlnMetAsnGlnIleGlnSerValGlu >>>> Target Intron 16 >>>>
|||||||||||||||||||||||||||||| 86 bp
AlaGlnMetAsnGlnIleGlnSerValGlu++
GCACAGATGAACCAGATCCAGTCTGTGGAGgt
GlyGlnProLeuAlaArgArgProArgAlaThrGlyArgThrLysArg--CysGln
||||||||| |||||||||||||||||||||||||||||| ## |||
++GlyGlnProProAlaArgArgProArgAlaThrGlyArgThrGluGln##LeuGln
agGGCCAGCCACCTGCCAGGAGGCCACGGGCGACAGGAAGGACCGAGCAGCGCTGCAG
ProArgAspValThrLysLysThrCysAsnSerAsnAspGlyLysLysLysGlyMetG
||||||||||||||| ||| |||||||||||||||||| |
ProArgAspValThrArgAsnThrArgAsnSerAsnAspGlyLysArgGlu---TrpG
CCACGGGATGTGACCAGGAACACACGCAACTCCAACGATGGAAAAAGGGAA---TGGG
lyLysLysLysThrAspProGlyArgGlyArgGluIleGlnGly-IlePhePheLysG
|| |||||||||||||||||||||||||||||| ||| #||| |||||||
lyThrLysLysThrAspProGlyArgGlyArgGluArgGlnAsp#Ile---PheLysG
GAACAAAGAAAACCGATCCTGGGAGGGGGCGGGAAAGACAGGACTATT---TTTAAAG
luAspSerHisLysGluSerAsnAspCys
|||||||| ||||||||| ||||||
luAspSerGlnLysGluSerAspAspCys
AGGATTCTCAAAAGGAAAGCGATGACTGT
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