| Basic information |
| Official Symbol | DNAH11 |
| Description | dynein, axonemal, heavy chain 11 |
| Other Aliases | CILD7, DNAHBL, DNAHC11, DNHBL, DPL11 |
| Other Description | axonemal beta dynein heavy chain 11; axonemal dynein heavy chain 11; ciliary dynein heavy chain 11; dynein heavy chain 11, axonemal; dynein, axonemal, heavy polypeptide 11; dynein, ciliary, heavy chain 11 |
| Mutation type | premature termination 2237:V->TAG |
| Location | Scaffold000410_1:3951515 4154892 + |
| Wiki | Wikipedia GeneCard |
| Sequence |
| DNAH11 |
TCCCCCGTGGTAGCCCTGGAGGTGCTAGGCTTTCAGGAAGCCTCCCTTCG CCTCACCCCGGGCGCGGGTTTGGAGGCGGCGGACGTGATGGAGTTGGAGG AGGAGGACGAGGAAGAGGAGGCAGCGGCCGCCAGGAAAGCGCGGACTTTC GGCCAAGACACGCGGGTGCGCTTCCTCCGCGGCCGCCTGGAGCAGATGCT GAGGTGCCCGGAGGAGAAATGGAGCCAGTATTTGGAGAATGAGGACAACC GACAGGTCCTGGGGGACTTTCTGGAGAGCACCAACCCGACCTGTCTTGTA TTCAGCCTAGCCGCAGCCGGGAGACTTGCGGCCTTCCAGGAGATTCCAAG AGATGCAAAACATAAACTTGTTTATATTGCCAAGAAGGTTATGGAAAGCA CTGGAGTAAAGGATTTCTCTCAAACAGTTTTATTTGGAGAGTTACCTACA TCCTCTCTTGGATATGTAACTGCTTTCTTAGAAGAGATTTTAGTGCCAAT TCTTTCTAATAAGAACAACCATAAATCCTGGTCCTGTTTTACTTCGCAAG ATATGGAATGTCACATAGAAGTCATGAAGACTAAGATGCATATATTTAAG GGCCAAATGTCTAGAAGAACTCTGCTACCAATTCCTACTATTGCAGGAAA AATTGACCTAGATCAGAATTATTCAGAGACCAAGCTGCAGTCAGATGAAA GGATAATACTCCACACAATTGAATCCGTGATTATTAAATGGTCACATCAA ATCCAAGAAATTGTAGAAAAAGATTCAGTACAGTCTTTGCTGAATAGTCT TCACTCTAATCCTCAAACTGAGCTGGATTTCTGGACAATGAGAAGAGAGA ATCTATCATGCACTTACGATCAGCTTCAGACTCCTGTTGTCCTCAAAATG GTTAAGATCCTGAAAAAGAAACAAAGTAGCTATTTTCCTACTTTGAAGGG CATCCTCATGACTGTGGAAAATGCTCTTCTTGAAGCCCAAGATGTGGAAC TTTATCTGAGACCTCTGAGGAAACACATTCAGTCTCTCCAGGAGACGGAA TTCCCACAGATGCGCATATTAATCGCCCCATTGTTTCATACCATCTGTCT GATCTGGAGTCATTCCAAATTTTATAATACCCCTGCTCGGGTTATAGTTT TATTGCAAGAGTTTTGTAACCTCTTCATTGACCAGGCAATAGCTTATCTT TCTCCTGAGGACCTTTTGAAGGGAGAAATTGAAGACTCACTGGAAAAAGT ACAGGTGGCCATTAACATCTTAAAGACTTTCAAAGATTCTTTTTTCAACC ATAGAAGAAAATTGTCAAGCTATTTTACAGGAAATAAGGAGCTGCGACCC TGGGATTTTCAGTCTCATCTGGTGTTTTGCAGATTTGACCAATTTCTTGA CCGCTTAATGAAAATAGAGGATGTATTTGTCACCATATTGGAATTTGAAA AGCTGGAAAGATTGGAATTCGGCGGTACCAGGGGAGCCATTTTAAATGAA CAGATCCATGAGATGAATGAAGCATTTATGGAACTCTGTGAAGTATTTAA ACTGAGCACTTATGACCCATCTGATTGCAGTAACATGGAATTTGAAAATG ATTATGTTATGTTTAAATCTGAAACTTTGGATTTTGATAGAAGGCTTGGA ACAATTCTTTGTGAGGGTTTCTACAACTGCAATGGTTTAGAAGCTGCATT TAAGCTTTTGACCATATTTGGGAATTTTCTGGAGAAGCCAGTTGTCATGG AAATTTTCAGCCCACATTACAACACACTAGTGCACATGTTTATTGCAGAG CTGGATATGTGTAAGCAATTGTACAATGAACATGTGAAACAGATTGAACG TGGACATGCAGTTCTTAATAAGAACATGCCATTTACTTCAGGAAATATCA AATGGGCCAGAGAAGTCCTTGAACGACTTCAAACGTTTTGGTCCAACTTT GCATCTCTCCAGTATCTATTCTTGAACAGTCCTGAGGATGCCTTAGTTTA TCAGAAGTATGTTGAAATGACCACTTTGCTAGACCAATTTGAAAATCACA TCTATAACAAGTGGAAAAGTAATGTGGATGAAATCTGTGCATTTAATTTG AACCAACCCTTGGTTAAATTCAGTGCCATAAATGGTCTTCTCAGTGTCAA CTTTGACCCAAAGCTAGTGGCTGTGTTGAGAGAAGTAAAATACCTCTTAA TGTTGAAGAAACCAAACCTACCAGATTCAGCTTTAACCATCTTCAAAAAG AGAAACACCATTTTAAAGTACATTGGAAATCTTGAGCTTCTTGTACAAGG ATATAATAAGCTGAAACAGACTCTTCTGGAAGTTGAATACCCTCTGATTG AAGATGAGCTGAGGACCATAGATGAGCAATTAACAGCAGCCACAACATGG TTGACATGGCAGGATGACTGCTGGGAATATATTGAGGCAGTGACGATGGC CACCTCTGAGTTGGAGCACAGAGTGGAGCGCACACAGAACAATGTGAAAC TGATCCAGCAGACAATGAGGGCTTGGGCGGAGAACACATTCCTCCCCAGG AGAGAGCACAGAAGGGAGGCCACCTTGACTTTAGAGGACAAGGGCGATTT GTTTACAAAAAAATACAAGTTAATTCAAGAAGATGGCTGCAGGATACACA GCTTGGTGGAGGAAAACAGGGAGCTCTTCAAAGCCAGCGCCTCTCTGGAT ACCTGGAAAATTTATGTAGAATTCATTGATGACATCGTGGTGGAAGGCTT TTTTCAGGCTATAATGCATGACTTGGACTTTTTTCTGATGAATACAGAGA AACAATTGAAACCTGCTCCACTTTTTCAAGCTCAAATGATGCTAATGCCT CCCGAGATTGTGTTTAAACCTTCTTTAGAGAGAGAGGTTGCGGATGGCTT TTATGACCTAGTAGAAGAAATGTTGTGCAGTAGTTTCAGAATGTCTGCCC AGATGAAGCGAGTAGCAGCACATCTGGAAATAGCAAATTACCAGAACGAT ATGGATAACATGTTGGGCCTGGCAGAGGTCAGGCAGGAGATAATGAAGAG AGTGGCAAGTGTCATCGACAAAGTCTTGGATTTCAGAAATAGTCTAGATA TCTACGCTTACCTTTGGGTAGATGACCGAGCTGAGTTTATGAAGCATTTT CTCCTGTATGGCCATACTGTATCATCCGAAGAAGTGGATGCTCAGACCAG TGAAGAAATCCCTGAACAACCACCAACTCTTGAACAATTCAAAGAACAGA TCGACATTTATGAGGCATTGTATGTTCAGATGAGCAAGTTTGATGACTTC AGAGTGTTTGATAGTTGGTTCAGAGTGGACCTGAAGCCATTCAAAGTGAG CTTGCTAACCATTATTAAGAAATGGAGTTGGATGTTTCAGGAGCATCTTT TGAGATTTGTCATCAACAGTCTGAATGAGCTACAAGAATTTATCAAGGAG ACAGATATAGGACTCCAGAGAGAACTCAATGAAGGTGATCATGATGGTTT AGTTGACATCATGGGGCATCTTCTGGCTGTCAGAAGCCGACAGAGAACTA CAGATGAGCTTTTTGAACCCCTAAAAGAAACCATCACACTCTTGGAAAGC TATGGCCAGAAGATGCCTGAGCAAGTCTATATTCAGCTAGAGGAATTACC TGAAAGATGGGAAACTACCAAAAAAATTGCAGCAACTGTCAGACATGAAG TTTCACCTCTCCAAAATGCAGAAGTCACTCTTATAAGGAAAAAATGTGTT TTGTTTGATGGAAAGCAGGAAGAATTCAGAGAGAGATTCAAATGCTATGC CCCTCTTGGATTTGATGCAGAAAATCCATATGCAGTGCTTGATAAGGCAA ATGAAGAGCTTGAGGCATTAGAAGAAGAAATGTTGCAGATGCAAGAATCA ACTCGTCTTTTTGATGTTGCTCCTCCAGAGTACAAACAAATGAAGCAGTG TCGCAAAGAAATAAAACTACTGAAGGGACTCTGGGATGTCATTATTTATG TTAGAAGAAGCATTGATAATTGGACTAAAACCCAGTGGAGACAGATTAAT GTGGAACAGATGGATGTAGAACTCAGAAGGTTTGCCAAGGCGAGTTCCAT AACTGAAATTTGGTCACTAGACAAGGAAGTTCGTGTTTGGGATGCTTACT CAGGCCTGGAAGGTACAGTGAAGGACATGGCAACCTCTCTGAGAGCTGTC ACAGAATTACAAAGCCCTGCCCTCAGGGACAGGCATTGGCACCAGCTGAT GAAGGCCATTGGGGTCAAGTTTTCAATAAATGAAGACACCACCTTGGCAG ATCTGCTAGCGCTGCAGCTGCACAGAGTGGAAGATGACGTCCGAAGGATC GTGGACAAAGCGATGAAAGAACTGGGGACTGAGAAGGTTATTACTGAAAT CAATCAGACCTGGGCGACTATGGAGTTTTCTTATGAAGTTCACTATCGAA CAGGCATTCCGTTATTGAAGTCTGATGAACAACTCTTTGAAACTCTTGAG CATAACCAAGTTCAGTTGCAGACTCTTCTTCAAAGCAAGTATGTGGAATT TTTCATCGAACAAGTATTAAGCTGGCAAAATAAATTAAACATAGCAGACT CAGTGATCTTTACTTGGATGGAAGTCCAGCGAACTTGGTCTCACCTGGAA AGCATCTTTGTTTGTTCAGAAGATATTCGAATCCAGCTTGGGGAAGATGC TAGGAGATTCGATGGAGTAGATGCTGAATTTAAGGAGTTAATGTTCAAGA CAGCCAAAATAAAAAATGTTTTAGAAGCAACATGCAGACCTAATCTCTAT GAAAAACTTAAAGATTTACAGTACAGGCTTTCTTTTTGTGAAAAAGCTCT TGCTGAATACCTGGAAACCAAGCGTGTGGCTTTTCCTCGCTTCTATTTCA TCTCTTCTGTCGACTTGCTTGATATTCTCTCAAAGGGAGCTCAGCCTAAA CAGGTCACACGACACCTTGCCAAACTTTTTGACAGCCTCGCTGATCTGCA GTTTGATGATAATCACGATGTTTCTGCACATCGAGCAGTTGGAATGTACA GCAAAGAAAAGGAATATGTCCCATTCCAAGCTGAGTGTGAATGCATAGGC CATGTGGAAACATGGCTTCAGCAACTTGAACAGGCCATGCAAGAAACAGT GCGTCATTCTATCACAGAAGCCATAGCGGCCTATGAGGACAAACCCAGGG AACTGTGGATTTTTGATTTCCCAGCTCAAGTTGCCCTAACCAGCTCACAA ATATGGTGGACTACAGATGTAGGAATAGCCTTCAGTAGACTAGAGGAAGG CTATGAAACGGCTCTAAAGGATTTCCATAAAAAACAGATTTCCCAGTTGA ATACACTGATTACCCTTTTGCTCGGAGAACTCCCATCTGGAGACAGGCAG AAGATCATGGCAATTTGTACTATAGATGTCCATGCCAGAGATGTGGTGGC TAAACTTATTTCACAGAAGTTTCAGGTTGTCAGTCCCCAGGCTTTCGCTT GGCTATCTCAACTTCGTCACCAGTGGGAAGACACCCAGAAGCACTGTTAT GTCAATATTTGCGATGCCCAGTTCCAGTACTTCTATGAATACTTAGGAAA TAGTCCTCGATTGGTGATCACTCCTCTGACTGACAGATGTTATATTACCT TGACTCAGTCACTTCATCTGACCATGAGTGGGGCTCCAGCTGGCCCAGCT GGTACAGGGAAAACAGAAACCACCAAAGATCTGGGCCGTGCCCTTGGCAT GATGGTTTATGTCTTCAACTGTTCAGAGCAAATGGACTACAAATCCATAG GAAATATCTATAAGGGACTGGTGCAGACAGGAGCTTGGGGCTGTTTTGAT GAGTTCAATCGAATCGCTGTGGAAGTTCTGTCGGTGGTCGCAGTACAAGT GAAAATGATTCACGATGCTATCAGGAACAGGAAAAAGAGATTTGTATTTC TTGGGGAAGCTATCACGCTCAAGCCATCAGTTGGAATATTTATTACCATG AACCCAGGATACGCTGGTCGAACTGAATTACCAGAAAATCTCAAAGCTCT TTTCAGACCCTGTGCCATGGTGGCCCCTGACATTGAGCTAATATGTGAAA TCATGTTAGTTGCTGAAGGATTTGTGGATGCACGCTCTCTGGCCCGGAAA TTCATTACATTGTACACGCTCTGCAAAGAACTCCTCTCCAAGCAGGATCA TTATGATTGGGGACTTCGTGCTATTAAATCTGTCTTGGTTGTAGCCGGCT CTCTGAAACGAGGAGATAAAAATAGACCTGAAGATCAGGTACTCATGAGA GCACTGAGGGACTTCAATATGCCTAAAATAGTGACTGACGACATCCCAGT GTTTCTGGGCCTGATCAGTGACCTGTTTCCAGCCTTGGATGTGCCCCGGA GAAGGAAACTACACTTTGAACAGATGGTCAGGCAGTCTACCCTGGAGCTC CGCCTGCAGCCTGAAGATAGCTTCATCCTCAAAGTTGTCCAGCTTGAGGA GCTGTTGGCTGTGCGGCATTCTGTCTTTGTGGTTGGAAATGCGGGCACAG GAAAGAGCCAGATTTTGCGAACACTGAACCAAACATATGTTAACATGAAA CAGAAACCCGTTTGGAATGACTTAAACCCTAAAGCTGTAACAACAGATGA ACTCTTTGGTTTCATACATCATGCTACCCGAGAATGGAAAGATGGCAAAC ACTAGGATTGTTTACTTGTAGGTCTCTTCTCATCCATTCTGCGGGAACAA GCAAATCTTATGCATGATGGACCGAAATGGATAGTGCTGGATGGAGATAT TGACCCCATGTGGATTGAATCACTAAATACTGTCATGGATGACAACAAGG TGCTGACCCTCGCCAGCAATGAGCGTGTAGCCCTCACTCCTTTCATGAGG CTCCTGTTCGAGATAAGCCACTTGAGAACGGCAACCCCAGCGACTGTATC CAGAGCTGGTATTCTGTATGTGAACCCACAAGATTTGGGCTGGAATCCGT ATGTGGCCAGTTGGATAGACAGAAGGCAACATCAATCAGAAAAGGCTAAT TTAACTATCCTTTTCGATAAATACGTCCCTGCATGTTTGGATAAGCTGAG AACAAGCTTTAAGACTATCACTTCAATTCCAGAGAGTAGCCTGGTGCAGA CTCTCTGTGTTCTTTTGGAGTGTTTGTTGACTCCTGAAAATGTACCATCT GACAGCCCAAAAGAAATCTATGAAGTCTATTTTGTCTTTGCTTGTATCTG GGCCTTTGGAGGCACCCTGCTACAAGACCAGCTTTTTGATTATCAAGCTG ATTTCAGCCGGTGGTGGCATAAAGAGATGAAGGCGGTGAAGTTTCCATTC CAGGGGACAATCTTTGACTATTACTTGGACCATAAGACTAAGAAATTCTT GCCTTGGGCTGAAAAAATTCCCCAGTTTACTATGGAGCCTGATGTACCTC TTCAG |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 4523 | 3 | 2487 | Premature termination 2237:V->TAG |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
AlaGlnValAlaAlaArgGluAlaArgAspPheArgGluAlaProThrLeuArgLeuT
||| ||| ||| ||| |||||| ||||||||||
SerProValValAlaLeuGluValLeuGlyPheGlnGluAla---SerLeuArgLeuT
TCCCCCGTGGTAGCCCTGGAGGTGCTAGGCTTTCAGGAAGCC---TCCCTTCGCCTCA
hrSerGlyAlaGlyLeuGluAlaValGlyAlaValGluLeuGluGluGluGluGluAs
|| |||||||||||||||||| ||||||||||||||| |||
hrProGlyAlaGlyLeuGluAlaAlaAspValMetGluLeuGluGluGluAspGluGl
CCCCGGGCGCGGGTTTGGAGGCGGCGGACGTGATGGAGTTGGAGGAGGAGGACGAGGA
nGluGluGluAlaAlaAlaArgArgAlaArgSerPheAlaGlnAspAlaArgValArg
|||||| |||||||||||| |||||| ||| |||||| |||||||||
uGluGluAlaAlaAlaAlaArgLysAlaArgThrPheGlyGlnAspThrArgValArg
AGAGGAGGCAGCGGCCGCCAGGAAAGCGCGGACTTTCGGCCAAGACACGCGGGTGCGC
PheLeuGlyGlyArgLeuAlaMetMetLeuGlyPheThrGluGluLysTrpSerGlnT
|||||| ||||||||| |||||| |||||||||||||||||||
PheLeuArgGlyArgLeuGluGlnMetLeuArgCysProGluGluLysTrpSerGlnT
TTCCTCCGCGGCCGCCTGGAGCAGATGCTGAGGTGCCCGGAGGAGAAATGGAGCCAGT
yrLeuGluSerGluAspAsnArgGlnValLeuGlyGluPheLeuGluSerThrSerPr
|||||||| |||||||||||||||||||||||| ||||||||||||||| ||
yrLeuGluAsnGluAspAsnArgGlnValLeuGlyAspPheLeuGluSerThrAsnPr
ATTTGGAGAATGAGGACAACCGACAGGTCCTGGGGGACTTTCTGGAGAGCACCAACCC
oAlaCysLeuValPheSerPheAlaAlaSerGlyArgLeuAlaAlaSerGlnGlu >
| ||||||||||||||| |||||| ||||||||||||||| ||||||
oThrCysLeuValPheSerLeuAlaAlaAlaGlyArgLeuAlaAlaPheGlnGlu++
GACCTGTCTTGTATTCAGCCTAGCCGCAGCCGGGAGACTTGCGGCCTTCCAGGAGgt
>>> Target Intron 1 >>>> IleProArgAspAlaAsnHisLysLeuValPh
7734 bp ||||||||||||||| ||||||||||||
++IleProArgAspAlaLysHisLysLeuValTy
agATTCCAAGAGATGCAAAACATAAACTTGTTTA
eIleSerLysLysIleThrGluSerIleGlyValAsnAspPheSerGlnValValLeu
||| |||||| |||||| |||||| |||||||||||| ||||||
rIleAlaLysLysValMetGluSerThrGlyValLysAspPheSerGlnThrValLeu
TATTGCCAAGAAGGTTATGGAAAGCACTGGAGTAAAGGATTTCTCTCAAACAGTTTTA
PheGlyGluLeuProAlaLeuSerLeuGlyHisValSerAlaPheLeuAspGlu >>
||||||||||||||| ||||||||| ||| ||||||||| |||
PheGlyGluLeuProThrSerSerLeuGlyTyrValThrAlaPheLeuGluGlu++
TTTGGAGAGTTACCTACATCCTCTCTTGGATATGTAACTGCTTTCTTAGAAGAGgt
>> Target Intron 2 >>>> IleLeuValProValLeuSerAsnLysAsnAsn
9872 bp |||||||||||| ||||||||||||||||||
++IleLeuValProIleLeuSerAsnLysAsnAsn
agATTTTAGTGCCAATTCTTTCTAATAAGAACAAC
HisLysSerTrpSerCysPheThrSerGlnAspMetGluTyrHisIleGluValMetL
||||||||||||||||||||||||||||||||||||||| ||||||||||||||||
HisLysSerTrpSerCysPheThrSerGlnAspMetGluCysHisIleGluValMetL
CATAAATCCTGGTCCTGTTTTACTTCGCAAGATATGGAATGTCACATAGAAGTCATGA
ysLysLysMetTyrIlePheArgGlyLysMetSerArgArgThrLeuLeuProIlePr
|| |||||| |||||| ||| |||||||||||||||||||||||||||||
ysThrLysMetHisIlePheLysGlyGlnMetSerArgArgThrLeuLeuProIlePr
AGACTAAGATGCATATATTTAAGGGCCAAATGTCTAGAAGAACTCTGCTACCAATTCC
oThrValAlaGlyLysMetAspLeuAspGlnAsnCysSerGluAsn{Ly} >>>> T
|||| ||||||||| ||||||||||||||| |||||| {||}
oThrIleAlaGlyLysIleAspLeuAspGlnAsnTyrSerGluThr{Ly}++
TACTATTGCAGGAAAAATTGACCTAGATCAGAATTATTCAGAGACC{AA}gt
arget Intron 3 >>>> {s}ProProSerAsnGluArgIleIleLeuHisAlaI
1585 bp {|} ||| |||||||||||||||||| |
++{s}LeuGlnSerAspGluArgIleIleLeuHisThrI
ag{G}CTGCAGTCAGATGAAAGGATAATACTCCACACAA
leGluSerValValIleGluTrpSerHisGlnIleGlnGluIleIleGluArgAspSe
||||||||||| ||| |||||||||||||||||||||||| ||| |||||
leGluSerValIleIleLysTrpSerHisGlnIleGlnGluIleValGluLysAspSe
TTGAATCCGTGATTATTAAATGGTCACATCAAATCCAAGAAATTGTAGAAAAAGATTC
rValGlnArgLeuLeuAsnGlyLeuHisLeuSerProGlnAlaGluLeuAspPheTrp
||||||| ||||||||| |||||| |||||| |||||||||||||||
rValGlnSerLeuLeuAsnSerLeuHisSerAsnProGlnThrGluLeuAspPheTrp
AGTACAGTCTTTGCTGAATAGTCTTCACTCTAATCCTCAAACTGAGCTGGATTTCTGG
MetMetArgArgGluAsnLeuSerCysIleTyrAspGln >>>> Target Intro
|||||||||||||||||||||||| ||||||||| 1694 bp
ThrMetArgArgGluAsnLeuSerCysThrTyrAspGln++
ACAATGAGAAGAGAGAATCTATCATGCACTTACGATCAGgt
n 4 >>>> LeuGlnAlaProValValLeuLysMetValLysIleLeuThrThrLys
|||||| |||||||||||||||||||||||||||||| |||
++LeuGlnThrProValValLeuLysMetValLysIleLeuLysLysLys
agCTTCAGACTCCTGTTGTCCTCAAAATGGTTAAGATCCTGAAAAAGAAA
GlnSerSerTyrPheProThrLeuLysAspIlePheLeuAlaValGluAsn{A} >>
||||||||||||||||||||||||||| ||| |||||||||{|}
GlnSerSerTyrPheProThrLeuLysGlyIleLeuMetThrValGluAsn{A}++
CAAAGTAGCTATTTTCCTACTTTGAAGGGCATCCTCATGACTGTGGAAAAT{G}gt
>> Target Intron 5 >>>> {la}LeuLeuGluAlaGlnAspValGluLeuTy
4203 bp {||}|||||||||||||||||||||||||||||
++{la}LeuLeuGluAlaGlnAspValGluLeuTy
ag{CT}CTTCTTGAAGCCCAAGATGTGGAACTTTA
rLeuArgProLeuArgArgHisIleGlnCysLeuGlnGluThrGluPheProGlnThr
|||||||||||||||| ||||||||| ||||||||||||||||||||||||
rLeuArgProLeuArgLysHisIleGlnSerLeuGlnGluThrGluPheProGlnMet
TCTGAGACCTCTGAGGAAACACATTCAGTCTCTCCAGGAGACGGAATTCCCACAGATG
ArgIleLeuIleAlaProLeuPheHisThrIleCysLeuIleTrpSerHisSerLysP
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ArgIleLeuIleAlaProLeuPheHisThrIleCysLeuIleTrpSerHisSerLysP
CGCATATTAATCGCCCCATTGTTTCATACCATCTGTCTGATCTGGAGTCATTCCAAAT
heTyrAsnThrProAlaArgValIleValLeuLeuGlnGluPheCysAsnLeuPheIl
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
heTyrAsnThrProAlaArgValIleValLeuLeuGlnGluPheCysAsnLeuPheIl
TTTATAATACCCCTGCTCGGGTTATAGTTTTATTGCAAGAGTTTTGTAACCTCTTCAT
eAsnGln >>>> Target Intron 6 >>>> AlaThrAlaTyrLeuSerProG
| ||| 7705 bp ||| ||||||||||||||||
eAspGln++ ++AlaIleAlaTyrLeuSerProG
TGACCAGgt agGCAATAGCTTATCTTTCTCCTG
luAspLeuLeuArgGlyGluIleGluGluSerLeuGluLysValGlnValAlaValAs
||||||||||| |||||||||||| |||||||||||||||||||||||| ||
luAspLeuLeuLysGlyGluIleGluAspSerLeuGluLysValGlnValAlaIleAs
AGGACCTTTTGAAGGGAGAAATTGAAGACTCACTGGAAAAAGTACAGGTGGCCATTAA
nIleLeuLysThrPheLysAsnSerPhePheAsnTyrArgLysLysLeuAlaSerTyr
||||||||||||||||||| |||||||||||| ||| |||||| ||||||
nIleLeuLysThrPheLysAspSerPhePheAsnHisArgArgLysLeuSerSerTyr
CATCTTAAAGACTTTCAAAGATTCTTTTTTCAACCATAGAAGAAAATTGTCAAGCTAT
PheMetGlyArgLys<->LeuArgProTrpAspPheGlnSerHisLeuValPheCysA
||| ||| ||| ||||||||||||||||||||||||||||||||||||||||
PheThrGlyAsnLysGluLeuArgProTrpAspPheGlnSerHisLeuValPheCysA
TTTACAGGAAATAAGGAGCTGCGACCCTGGGATTTTCAGTCTCATCTGGTGTTTTGCA
rgPheAspLysPheLeuAspArgLeuIleLysIleGlu >>>> Target Intron
|||||||| ||||||||||||||| ||||||||| 1704 bp
rgPheAspGlnPheLeuAspArgLeuMetLysIleGlu++
GATTTGACCAATTTCTTGACCGCTTAATGAAAATAGAGgt
7 >>>> AspIlePheAlaThrThrLeuGluPheGluLysLeuGluArgLeuGluP
||| ||| ||| |||||||||||||||||||||||||||||||
++AspValPheValThrIleLeuGluPheGluLysLeuGluArgLeuGluP
agGATGTATTTGTCACCATATTGGAATTTGAAAAGCTGGAAAGATTGGAAT
heGlyGlyThrLysGlyAlaIleLeuAsnGlyGlnValHisGluMetSerGluGluLe
||||||||||| ||||||||||||||| ||| ||||||||| |||
heGlyGlyThrArgGlyAlaIleLeuAsnGluGlnIleHisGluMetAsnGluAlaPh
TCGGCGGTACCAGGGGAGCCATTTTAAATGAACAGATCCATGAGATGAATGAAGCATT
uMetGluLeuCysLysLeuPheLysGlnSerThrTyrAspProSerAspCysThrAsn
|||||||||||| |||||| |||||||||||||||||||||||| |||
eMetGluLeuCysGluValPheLysLeuSerThrTyrAspProSerAspCysSerAsn
TATGGAACTCTGTGAAGTATTTAAACTGAGCACTTATGACCCATCTGATTGCAGTAAC
Met >>>> Target Intron 8 >>>> GluPheGluSerAspTyrValAlaPh
||| 9079 bp ||||||||| ||||||||| ||
Met++ ++GluPheGluAsnAspTyrValMetPh
ATGgt agGAATTTGAAAATGATTATGTTATGTT
eLysSerLysThrLeuGluPheAspArgArgLeuGlyThrIleIleCysGluAlaPhe
||||||| |||||| |||||||||||||||||||||||| |||||| |||
eLysSerGluThrLeuAspPheAspArgArgLeuGlyThrIleLeuCysGluGlyPhe
TAAATCTGAAACTTTGGATTTTGATAGAAGGCTTGGAACAATTCTTTGTGAGGGTTTC
PheAsnCysAsnGlyLeuGluAlaAlaPheLys >>>> Target Intron 9 >>
|||||||||||||||||||||||||||||| 3523 bp
TyrAsnCysAsnGlyLeuGluAlaAlaPheLys++
TACAACTGCAATGGTTTAGAAGCTGCATTTAAGgt
>> LeuLeuThrIlePheGlyAsnPheLeuGluLysProValValMetGluIlePhe
||||||||||||||||||||||||||||||||||||||||||||||||||||||
++LeuLeuThrIlePheGlyAsnPheLeuGluLysProValValMetGluIlePhe
agCTTTTGACCATATTTGGGAATTTTCTGGAGAAGCCAGTTGTCATGGAAATTTTC
SerLeuHisTyrSerThrLeuValHisMetPheAsnThrGluLeuAspValCysLysG
||| |||||| |||||||||||||||||| ||||||||| |||||||
SerProHisTyrAsnThrLeuValHisMetPheIleAlaGluLeuAspMetCysLysG
AGCCCACATTACAACACACTAGTGCACATGTTTATTGCAGAGCTGGATATGTGTAAGC
lnLeuTyrAsnGluHisMetLysGln >>>> Target Intron 10 >>>> Il
||||||||||||||||| |||||| 321 bp ||
lnLeuTyrAsnGluHisValLysGln++ ++Il
AATTGTACAATGAACATGTGAAACAGgt agAT
eGluCysGlyHisValValLeuAsnLysAsnMetProPheThrSerGlyAsnMetLys
|||| |||||| |||||||||||||||||||||||||||||||||||| |||
eGluArgGlyHisAlaValLeuAsnLysAsnMetProPheThrSerGlyAsnIleLys
TGAACGTGGACATGCAGTTCTTAATAAGAACATGCCATTTACTTCAGGAAATATCAAA
TrpAlaGlnGlnValLeuGlnArgLeuGlnMetPheTrpSerAsnPheAlaSerLeuA
|||||| |||||| ||||||||| ||||||||||||||||||||||||
TrpAlaArgGluValLeuGluArgLeuGlnThrPheTrpSerAsnPheAlaSerLeuG
TGGGCCAGAGAAGTCCTTGAACGACTTCAAACGTTTTGGTCCAACTTTGCATCTCTCC
rgTyr{Le} >>>> Target Intron 11 >>>> {u}PheLeuGlyAsnProA
|||{||} 699 bp {|}|||||| |||
lnTyr{Le}++ ++{u}PheLeuAsnSerProG
AGTAT{CT}gt ag{A}TTCTTGAACAGTCCTG
spHisAlaLeuValTyrGlnLysTyrValGluMetThrThrLeuLeuAspGlnPheGl
|||||||||||||||||||||||||||||||||||||||||||||||||||||
luAspAlaLeuValTyrGlnLysTyrValGluMetThrThrLeuLeuAspGlnPheGl
AGGATGCCTTAGTTTATCAGAAGTATGTTGAAATGACCACTTTGCTAGACCAATTTGA
uSerArgIleTyrAsnGluTrpLysSerAsnValAspGluIleCysGluPheAsnLeu
| ||||||||| ||||||||||||||||||||||||||| |||||||||
uAsnHisIleTyrAsnLysTrpLysSerAsnValAspGluIleCysAlaPheAsnLeu
AAATCACATCTATAACAAGTGGAAAAGTAATGTGGATGAAATCTGTGCATTTAATTTG
AsnGlnProLeuValLysPheSerAlaIleAsnGlyLeuLeuCysValAsnPheAspP
|||||||||||||||||||||||||||||||||||||||||| |||||||||||||
AsnGlnProLeuValLysPheSerAlaIleAsnGlyLeuLeuSerValAsnPheAspP
AACCAACCCTTGGTTAAATTCAGTGCCATAAATGGTCTTCTCAGTGTCAACTTTGACC
roLys >>>> Target Intron 12 >>>> LeuValAlaValLeuArgGluVa
||||| 4359 bp |||||||||||||||||||||||
roLys++ ++LeuValAlaValLeuArgGluVa
CAAAGgt agCTAGTGGCTGTGTTGAGAGAAGT
lLysTyrLeuLeuMetLeuLysLysGlnAspIleProAspSerAlaLeuAlaIlePhe
||||||||||||||||||||||||| ||||||||||||||| ||||||
lLysTyrLeuLeuMetLeuLysLysProAsnLeuProAspSerAlaLeuThrIlePhe
AAAATACCTCTTAATGTTGAAGAAACCAAACCTACCAGATTCAGCTTTAACCATCTTC
LysLysArgAsnThrIleLeuLys >>>> Target Intron 13 >>>> TyrI
|||||||||||||||||||||||| 153 bp ||||
LysLysArgAsnThrIleLeuLys++ ++TyrI
AAAAAGAGAAACACCATTTTAAAGgt agTACA
leGlyAsnLeuAspLeuLeuValGlnGlyTyrAsnLysLeuLysGlnThrLeuLeuGl
||||||||||| ||||||||||||||||||||||||||||||||||||||||||||
leGlyAsnLeuGluLeuLeuValGlnGlyTyrAsnLysLeuLysGlnThrLeuLeuGl
TTGGAAATCTTGAGCTTCTTGTACAAGGATATAATAAGCTGAAACAGACTCTTCTGGA
uValGluTyrProLeuIleGluAspGluLeuArgAlaIleAspGluGlnLeuThrAla
|||||||||||||||||||||||||||||||||| |||||||||||||||||||||
uValGluTyrProLeuIleGluAspGluLeuArgThrIleAspGluGlnLeuThrAla
AGTTGAATACCCTCTGATTGAAGATGAGCTGAGGACCATAGATGAGCAATTAACAGCA
AlaThrThrTrpLeuThrTrpGlnAspAspCysTrpGlyTyrIleGluArgValArgA
|||||||||||||||||||||||||||||||||||| ||||||||| |||
AlaThrThrTrpLeuThrTrpGlnAspAspCysTrpGluTyrIleGluAlaValThrM
GCCACAACATGGTTGACATGGCAGGATGACTGCTGGGAATATATTGAGGCAGTGACGA
laAlaThrSerGluLeuGluHisArgValGluArgThrGlnLysAsnValLysValIl
||||||||||||||||||||||||||||||||||||||| ||||||||| ||
etAlaThrSerGluLeuGluHisArgValGluArgThrGlnAsnAsnValLysLeuIl
TGGCCACCTCTGAGTTGGAGCACAGAGTGGAGCGCACACAGAACAATGTGAAACTGAT
eGlnGlnThrMetArgGlyTrpAlaArgCysValLeuProProArgArgGluHisArg
|||||||||||||||| |||||| ||||||||||||||||||
eGlnGlnThrMetArgAlaTrpAlaGluAsnThrPheLeuProArgArgGluHisArg
CCAGCAGACAATGAGGGCTTGGGCGGAGAACACATTCCTCCCCAGGAGAGAGCACAGA
ArgGluAlaAlaPheThrLeuGluAspLysGlyAspLeuPheThrLysLysTyrLysL
||||||||| |||||||||||||||||||||||||||||||||||||||||||
ArgGluAlaThrLeuThrLeuGluAspLysGlyAspLeuPheThrLysLysTyrLysL
AGGGAGGCCACCTTGACTTTAGAGGACAAGGGCGATTTGTTTACAAAAAAATACAAGT
euIleGlnGlyAspGlyCysLysIleHisAsnLeuValGlu >>>> Target Int
|||||||| ||||||||| |||||| ||||||||| 7737
euIleGlnGluAspGlyCysArgIleHisSerLeuValGlu++
TAATTCAAGAAGATGGCTGCAGGATACACAGCTTGGTGGAGgt
ron 14 >>>> GluAsnArgLysLeuPheLysAlaAsnProSerLeuAspThrTrp
bp ||||||||| |||||||||||| |||||||||||||||
++GluAsnArgGluLeuPheLysAlaSerAlaSerLeuAspThrTrp
agGAAAACAGGGAGCTCTTCAAAGCCAGCGCCTCTCTGGATACCTGG
LysIleTyrValGluPheIleAspAspIleValValGluGlyPhePheGlnAlaIleM
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
LysIleTyrValGluPheIleAspAspIleValValGluGlyPhePheGlnAlaIleM
AAAATTTATGTAGAATTCATTGATGACATCGTGGTGGAAGGCTTTTTTCAGGCTATAA
etHisAspLeuAspPhePheLeuLysAsnThrGluLysGlnLeuLysProAlaProPh
||||||||||||||||||||||| ||||||||||||||||||||||||||||||
etHisAspLeuAspPhePheLeuMetAsnThrGluLysGlnLeuLysProAlaProLe
TGCATGACTTGGACTTTTTTCTGATGAATACAGAGAAACAATTGAAACCTGCTCCACT
ePheGlnAlaGlnMetIleLeuLeuProProGluIleValPheLysProSerLeuAsp
||||||||||||||| ||| ||||||||||||||||||||||||||||||
uPheGlnAlaGlnMetMetLeuMetProProGluIleValPheLysProSerLeuGlu
TTTTCAAGCTCAAATGATGCTAATGCCTCCCGAGATTGTGTTTAAACCTTCTTTAGAG
ArgGluAlaGlyAspGlyPheTyrAspLeuValGluGluMetLeuCysAsnSerPheA
|||||| |||||||||||||||||||||||||||||||||||| |||||||
ArgGluValAlaAspGlyPheTyrAspLeuValGluGluMetLeuCysSerSerPheA
AGAGAGGTTGCGGATGGCTTTTATGACCTAGTAGAAGAAATGTTGTGCAGTAGTTTCA
rgMetSerAlaGlnMetAsnArgIleAlaThrHisLeuGluIleLysAsnTyrGln
||||||||||||||||| ||| ||| |||||||||||| |||||||||
rgMetSerAlaGlnMetLysArgValAlaAlaHisLeuGluIleAlaAsnTyrGln++
GAATGTCTGCCCAGATGAAGCGAGTAGCAGCACATCTGGAAATAGCAAATTACCAGgt
>>>> Target Intron 15 >>>> AsnAspMetAspAsnMetLeuGlyLeuAla
221 bp ||||||||||||||||||||||||||||||
++AsnAspMetAspAsnMetLeuGlyLeuAla
agAACGATATGGATAACATGTTGGGCCTGGCA
GluValArgGlnGluIleMetAsnArgValValAsnValIleAsnLysValLeuAspP
||||||||||||||||||||| |||||| |||||| |||||||||||||
GluValArgGlnGluIleMetLysArgValAlaSerValIleAspLysValLeuAspP
GAGGTCAGGCAGGAGATAATGAAGAGAGTGGCAAGTGTCATCGACAAAGTCTTGGATT
heArgAsnThrLeuGluThrHisThrTyrLeuTrpValAspAspArgAlaGluPheMe
|||||||| ||| ||||||||||||||||||||||||||||||||
heArgAsnSerLeuAspIleTyrAlaTyrLeuTrpValAspAspArgAlaGluPheMe
TCAGAAATAGTCTAGATATCTACGCTTACCTTTGGGTAGATGACCGAGCTGAGTTTAT
tLysHisPheLeuLeuTyrGlyHisAlaValSerSerAspGluMetAspAlaHisAla
||||||||||||||||||||||||| ||||||||| ||| ||||||
tLysHisPheLeuLeuTyrGlyHisThrValSerSerGluGluValAspAlaGlnThr
GAAGCATTTTCTCCTGTATGGCCATACTGTATCATCCGAAGAAGTGGATGCTCAGACC
AsnGluGluIleProGluGlnProProThrLeuGluGlnPheLysGluGln >>>>
||||||||||||||||||||||||||||||||||||||||||||||||
SerGluGluIleProGluGlnProProThrLeuGluGlnPheLysGluGln+-
AGTGAAGAAATCCCTGAACAACCACCAACTCTTGAACAATTCAAAGAACAGgc
Target Intron 16 >>>> IleAspIleTyrGluAlaLeuTyrValGlnMetSe
80 bp |||||||||||||||||||||||||||||||||||
++IleAspIleTyrGluAlaLeuTyrValGlnMetSe
agATCGACATTTATGAGGCATTGTATGTTCAGATGAG
rLysPheGluAspPheArgValPheAspSerTrpPheLysValAspMetLysProPhe
||||||| ||||||||||||||||||||||||||| |||||| |||||||||
rLysPheAspAspPheArgValPheAspSerTrpPheArgValAspLeuLysProPhe
CAAGTTTGATGACTTCAGAGTGTTTGATAGTTGGTTCAGAGTGGACCTGAAGCCATTC
LysValSerLeuLeuThrIleIleLysLysTrpSerTrpMetPheGlnGluHisLeuL
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
LysValSerLeuLeuThrIleIleLysLysTrpSerTrpMetPheGlnGluHisLeuL
AAAGTGAGCTTGCTAACCATTATTAAGAAATGGAGTTGGATGTTTCAGGAGCATCTTT
euArgPheValIleAsp{Se} >>>> Target Intron 17 >>>> {r}LeuA
|||||||||||||| {||} 232 bp {|}||||
euArgPheValIleAsn{Se}++ ++{r}LeuA
TGAGATTTGTCATCAAC{AG}gt ag{T}CTGA
snGluLeuGlnGluPheIleLysGluThrAspSerGlyLeuGlnArgGluLeuAsnGl
|||||||||||||||||||||||||||||||| |||||||||||||||||||||||
snGluLeuGlnGluPheIleLysGluThrAspIleGlyLeuGlnArgGluLeuAsnGl
ATGAGCTACAAGAATTTATCAAGGAGACAGATATAGGACTCCAGAGAGAACTCAATGA
uGlyAspHisAspGlyLeuValAspIleMetValHisLeuLeuAlaValArgSerArg
||||||||||||||||||||||||||||||| ||||||||||||||||||||||||
uGlyAspHisAspGlyLeuValAspIleMetGlyHisLeuLeuAlaValArgSerArg
AGGTGATCATGATGGTTTAGTTGACATCATGGGGCATCTTCTGGCTGTCAGAAGCCGA
GlnArgAlaThrAspGluLeuPheGluProLeuLysGluThrIleThrLeuLeuGluS
|||||| |||||||||||||||||||||||||||||||||||||||||||||||||
GlnArgThrThrAspGluLeuPheGluProLeuLysGluThrIleThrLeuLeuGluS
CAGAGAACTACAGATGAGCTTTTTGAACCCCTAAAAGAAACCATCACACTCTTGGAAA
erTyrGlyGlnLysMetProGluGlnValTyrIleGlnLeuGlu >>>> Target
|||||||||||||||||||||||||||||||||||||||||||| 90
erTyrGlyGlnLysMetProGluGlnValTyrIleGlnLeuGlu++
GCTATGGCCAGAAGATGCCTGAGCAAGTCTATATTCAGCTAGAGgt
Intron 18 >>>> GluLeuProGluArgTrpGluThrThrLysLysIleAlaAla
23 bp ||||||||||||||||||||||||||||||||||||||||||
++GluLeuProGluArgTrpGluThrThrLysLysIleAlaAla
agGAATTACCTGAAAGATGGGAAACTACCAAAAAAATTGCAGCA
ThrValArgHisGluValSerProLeuHisAsnAlaGluValThrLeuIleArgLysL
||||||||||||||||||||||||||| ||||||||||||||||||||||||||||
ThrValArgHisGluValSerProLeuGlnAsnAlaGluValThrLeuIleArgLysL
ACTGTCAGACATGAAGTTTCACCTCTCCAAAATGCAGAAGTCACTCTTATAAGGAAAA
ysCysIleLeuPheAsp >>>> Target Intron 19 >>>> AlaLysGlnAl
||||| ||||||||| 372 bp ||||||
ysCysValLeuPheAsp++ ++GlyLysGlnGl
AATGTGTTTTGTTTGATgt agGGAAAGCAGGA
aGluPheArgGluArgPheArgHisTyrAlaProLeuGlyPheAsnAlaGluAsnPro
|||||||||||||||||| |||||||||||||||||| ||||||||||||
uGluPheArgGluArgPheLysCysTyrAlaProLeuGlyPheAspAlaGluAsnPro
AGAATTCAGAGAGAGATTCAAATGCTATGCCCCTCTTGGATTTGATGCAGAAAATCCA
TyrThrAlaLeuAspLys >>>> Target Intron 20 >>>> AlaAsnGluG
||| ||||||||| 9365 bp ||||||||||
TyrAlaValLeuAspLys++ ++AlaAsnGluG
TATGCAGTGCTTGATAAGgt agGCAAATGAAG
luLeuGluAlaLeuGluGluGluMetLeuGlnMetGlnGluSerThrArgLeuPheGl
||||||||||||||||||||||||||||||||||||||||||||||||||||||||
luLeuGluAlaLeuGluGluGluMetLeuGlnMetGlnGluSerThrArgLeuPheAs
AGCTTGAGGCATTAGAAGAAGAAATGTTGCAGATGCAAGAATCAACTCGTCTTTTTGA
uValAlaLeuProGluTyrLysGlnMetLysGlnCysArgLysGluIleLysLeuLeu
|||||| ||||||||||||||||||||||||||||||||||||||||||||||||
pValAlaProProGluTyrLysGlnMetLysGlnCysArgLysGluIleLysLeuLeu
TGTTGCTCCTCCAGAGTACAAACAAATGAAGCAGTGTCGCAAAGAAATAAAACTACTG
LysGlyLeuTrpAspValIleIleTyrValArg >>>> Target Intron 21 >
||||||||||||||||||||||||||||||||| 1497 bp
LysGlyLeuTrpAspValIleIleTyrValArg++
AAGGGACTCTGGGATGTCATTATTTATGTTAGAgt
>>> ArgSerIleAspAsnTrpThrLysThrGlnTrpArgGlnIleHisValGluGl
|||||||||||||||||||||||||||||||||||||||||| ||||||||
++ArgSerIleAspAsnTrpThrLysThrGlnTrpArgGlnIleAsnValGluGl
agAGAAGCATTGATAATTGGACTAAAACCCAGTGGAGACAGATTAATGTGGAACA
nMetAspValGluLeuArgArgPheAlaLysAlaSerSerIleThr >>>> Targe
||||||||||||||||||||||||||||||||||||||||||||||
nMetAspValGluLeuArgArgPheAlaLysAlaSerSerIleThr++
GATGGATGTAGAACTCAGAAGGTTTGCCAAGGCGAGTTCCATAACTgt
t Intron 22 >>>> GluIleTrpSerLeuAsnLysGluValArgValTrpAspA
1462 bp ||||||||||||||| ||||||||||||||||||||||
++GluIleTrpSerLeuAspLysGluValArgValTrpAspA
agGAAATTTGGTCACTAGACAAGGAAGTTCGTGTTTGGGATG
laTyrThrGlyLeuGluGlyThrValLysAspMetThrAlaSerLeuArgAlaIleTh
||||| ||||||||||||||||||||||||||| |||||||||||| ||
laTyrSerGlyLeuGluGlyThrValLysAspMetAlaThrSerLeuArgAlaValTh
CTTACTCAGGCCTGGAAGGTACAGTGAAGGACATGGCAACCTCTCTGAGAGCTGTCAC
rGluLeuGlnSerProAlaLeuArgAspArgHisTrpHisGlnLeuMetLysAlaIle
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
rGluLeuGlnSerProAlaLeuArgAspArgHisTrpHisGlnLeuMetLysAlaIle
AGAATTACAAAGCCCTGCCCTCAGGGACAGGCATTGGCACCAGCTGATGAAGGCCATT
Gly >>>> Target Intron 23 >>>> ValLysPheLeuIleAsnGluAlaT
||| 3769 bp ||||||||| ||||||||| |
Gly++ ++ValLysPheSerIleAsnGluAspT
GGGgt agGTCAAGTTTTCAATAAATGAAGACA
hrThrLeuAlaAspLeuLeuAlaLeuArgLeuHisArgValGluAspAspValArgAr
|||||||||||||||||||||||||| |||||||||||||||||||||||||||||
hrThrLeuAlaAspLeuLeuAlaLeuGlnLeuHisArgValGluAspAspValArgAr
CCACCTTGGCAGATCTGCTAGCGCTGCAGCTGCACAGAGTGGAAGATGACGTCCGAAG
gIleValAspLysAlaValLysGluLeuGlyThrGluLys >>>> Target Intr
|||||||||||||||| ||||||||||||||||||||| 1245 b
gIleValAspLysAlaMetLysGluLeuGlyThrGluLys++
GATCGTGGACAAAGCGATGAAAGAACTGGGGACTGAGAAGgt
on 24 >>>> ValIleThrGluIleSerGlnThrTrpAlaThrMetLysPheSerT
p ||||||||||||||| |||||||||||||||||| |||||||
++ValIleThrGluIleAsnGlnThrTrpAlaThrMetGluPheSerT
agGTTATTACTGAAATCAATCAGACCTGGGCGACTATGGAGTTTTCTT
yrGluValHisTyrArgThrGlyIleProLeuLeuLysSerAspGluGlnLeuPheGl
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
yrGluValHisTyrArgThrGlyIleProLeuLeuLysSerAspGluGlnLeuPheGl
ATGAAGTTCACTATCGAACAGGCATTCCGTTATTGAAGTCTGATGAACAACTCTTTGA
uThrLeuGluHisAsnGln >>>> Target Intron 25 >>>> ValGlnLeu
||||||||||||||||||| 1805 bp |||||||||
uThrLeuGluHisAsnGln++ ++ValGlnLeu
AACTCTTGAGCATAACCAAgt agGTTCAGTTG
GlnThrLeuLeuGlnSerLysTyrValGluTyrPheIleGluGlnValLeuSerTrpG
|||||||||||||||||||||||||||||| |||||||||||||||||||||||||
GlnThrLeuLeuGlnSerLysTyrValGluPhePheIleGluGlnValLeuSerTrpG
CAGACTCTTCTTCAAAGCAAGTATGTGGAATTTTTCATCGAACAAGTATTAAGCTGGC
lnAsnLysLeuAsnIleAlaAspLeuValIlePheThrTrpMetGluValGlnArgTh
||||||||||||||||||||||| ||||||||||||||||||||||||||||||||
lnAsnLysLeuAsnIleAlaAspSerValIlePheThrTrpMetGluValGlnArgTh
AAAATAAATTAAACATAGCAGACTCAGTGATCTTTACTTGGATGGAAGTCCAGCGAAC
rTrpSerHisLeuGluSerIlePheValCysSerGluAspIleArgIleGlnLeuVal
|||||||||||||||||||||||||||||||||||||||||||||||||||||||
rTrpSerHisLeuGluSerIlePheValCysSerGluAspIleArgIleGlnLeuGly
TTGGTCTCACCTGGAAAGCATCTTTGTTTGTTCAGAAGATATTCGAATCCAGCTTGGG
LysAspAlaArgArgPheAspGlyValAspAlaGluPheLys >>>> Target In
||||||||||||||||||||||||||||||||||||||| 863
GluAspAlaArgArgPheAspGlyValAspAlaGluPheLys++
GAAGATGCTAGGAGATTCGATGGAGTAGATGCTGAATTTAAGgt
tron 26 >>>> GluLeuMetPheLysThrAlaLysValGluAsnValLeuGluAl
bp |||||||||||||||||||||||| ||||||||||||||
++GluLeuMetPheLysThrAlaLysIleLysAsnValLeuGluAl
agGAGTTAATGTTCAAGACAGCCAAAATAAAAAATGTTTTAGAAGC
aThrCysArgProAsnLeuTyrGluLysLeuLysAspLeuGlnSer{Ar} >>>> T
||||||||||||||||||||||||||||||||||||||||||| {||}
aThrCysArgProAsnLeuTyrGluLysLeuLysAspLeuGlnTyr{Ar}++
AACATGCAGACCTAATCTCTATGAAAAACTTAAAGATTTACAGTAC{AG}gt
arget Intron 27 >>>> {g}LeuSerLeuCysGluLysAlaLeuAlaGluTyr
1962 bp {|}|||||| ||||||||||||||||||||||||
++{g}LeuSerPheCysGluLysAlaLeuAlaGluTyr
ag{G}CTTTCTTTTTGTGAAAAAGCTCTTGCTGAATAC
LeuGluThrLysArgIleAlaPheProArgPheTyrPheValSerSerAlaAspLeuL
||||||||||||||| ||||||||||||||||||||| |||||| |||||||
LeuGluThrLysArgValAlaPheProArgPheTyrPheIleSerSerValAspLeuL
CTGGAAACCAAGCGTGTGGCTTTTCCTCGCTTCTATTTCATCTCTTCTGTCGACTTGC
euAspIleLeuSerLysGlyAlaGlnProLysGln >>>> Target Intron 28
||||||||||||||||||||||||||||||||||| 23573 bp
euAspIleLeuSerLysGlyAlaGlnProLysGln++
TTGATATTCTCTCAAAGGGAGCTCAGCCTAAACAGgt
>>>> ValThrCysHisLeuAlaLysLeuPheAspSerIleAlaAspLeuGlnPhe
|||||| |||||||||||||||||||||||| |||||||||||||||
++ValThrArgHisLeuAlaLysLeuPheAspSerLeuAlaAspLeuGlnPhe
agGTCACACGACACCTTGCCAAACTTTTTGACAGCCTCGCTGATCTGCAGTTT
GluAspAsnGlnAspValSerAlaHisArgAlaValGlyMetTyrSerLysGluLysG
|||||| ||||||||||||||||||||||||||||||||||||||||||||||
AspAspAsnHisAspValSerAlaHisArgAlaValGlyMetTyrSerLysGluLysG
GATGATAATCACGATGTTTCTGCACATCGAGCAGTTGGAATGTACAGCAAAGAAAAGG
luTyrValProPheGlnAlaGluCysGluCysValGlyHis >>>> Target Int
|||||||||||||||||||||||||||||||| |||||| 3691
luTyrValProPheGlnAlaGluCysGluCysIleGlyHis++
AATATGTCCCATTCCAAGCTGAGTGTGAATGCATAGGCCATgt
ron 29 >>>> ValGluThrTrpLeuLeuGlnLeuGluGlnThrMetGlnGluThr
bp ||||||||||||||| |||||||||||| ||||||||||||
++ValGluThrTrpLeuGlnGlnLeuGluGlnAlaMetGlnGluThr
agGTGGAAACATGGCTTCAGCAACTTGAACAGGCCATGCAAGAAACA
ValArgHisSerIleThrGluAlaIleValAlaTyrGluGluLysProArgGluLeuT
||||||||||||||||||||||||||| ||||||||| ||||||||||||||||
ValArgHisSerIleThrGluAlaIleAlaAlaTyrGluAspLysProArgGluLeuT
GTGCGTCATTCTATCACAGAAGCCATAGCGGCCTATGAGGACAAACCCAGGGAACTGT
rpIlePheAspPheProAlaGlnValAlaLeuThrSerSerGlnIleTrpTrpThrTh
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
rpIlePheAspPheProAlaGlnValAlaLeuThrSerSerGlnIleTrpTrpThrTh
GGATTTTTGATTTCCCAGCTCAAGTTGCCCTAACCAGCTCACAAATATGGTGGACTAC
rAspValGlyIleAlaPheSerArgLeuGluGluGlyTyrGluThrAlaLeuLysAsp
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
rAspValGlyIleAlaPheSerArgLeuGluGluGlyTyrGluThrAlaLeuLysAsp
AGATGTAGGAATAGCCTTCAGTAGACTAGAGGAAGGCTATGAAACGGCTCTAAAGGAT
PheHisLysLysGln >>>> Target Intron 30 >>>> IleSerGlnLeuA
||||||||||||||| 21797 bp |||||||||||||
PheHisLysLysGln++ ++IleSerGlnLeuA
TTCCATAAAAAACAGgt agATTTCCCAGTTGA
snThrLeuIleThrLeuLeuLeuGlyGluLeuProProGlyAspArgGlnLysIleMe
||||||||||||||||||||||||||||||||||| ||||||||||||||||||||
snThrLeuIleThrLeuLeuLeuGlyGluLeuProSerGlyAspArgGlnLysIleMe
ATACACTGATTACCCTTTTGCTCGGAGAACTCCCATCTGGAGACAGGCAGAAGATCAT
tThrIleCysThrIleAspValHisAlaArgAspValValAlaLysLeuIleSerGln
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||
tAlaIleCysThrIleAspValHisAlaArgAspValValAlaLysLeuIleSerGln
GGCAATTTGTACTATAGATGTCCATGCCAGAGATGTGGTGGCTAAACTTATTTCACAG
Lys >>>> Target Intron 31 >>>> GlnValValValSerProGlnAlaP
||| 2068 bp |||||||||||||||||||
Lys+- -+PheGlnValValSerProGlnAlaP
AAGgc ggTTTCAGGTTGTCAGTCCCCAGGCTT
heThrTrpLeuSerGlnLeuArgHisArgTrpGluAspThrGlnLysHisCysPheVa
|| ||||||||||||||||||||| |||||||||||||||||||||||| ||
heAlaTrpLeuSerGlnLeuArgHisGlnTrpGluAspThrGlnLysHisCysTyrVa
TCGCTTGGCTATCTCAACTTCGTCACCAGTGGGAAGACACCCAGAAGCACTGTTATGT
lAsnIleCysAspAlaGlnPheGlnTyrPheTyrGluTyrLeuGlyAsnSerProArg
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
lAsnIleCysAspAlaGlnPheGlnTyrPheTyrGluTyrLeuGlyAsnSerProArg
CAATATTTGCGATGCCCAGTTCCAGTACTTCTATGAATACTTAGGAAATAGTCCTCGA
LeuValIleThrProLeuThrAsp{Ar} >>>> Target Intron 32 >>>>
||||||||||||||||||||||||{||} 4462 bp
LeuValIleThrProLeuThrAsp{Ar}++ ++
TTGGTGATCACTCCTCTGACTGAC{AG}gt ag
{g}CysTyrIleThrLeuThrGlnSerLeuHisLeuThrMetSerGlyAlaProAlaG
{|}|||||||||||||||||||||||||||||||||||||||||||||||||||||||
{g}CysTyrIleThrLeuThrGlnSerLeuHisLeuThrMetSerGlyAlaProAlaG
{A}TGTTATATTACCTTGACTCAGTCACTTCATCTGACCATGAGTGGGGCTCCAGCTG
lyProAlaGlyThrGlyLysThrGluThrThrLysAspLeuGlyArgAlaLeuGlyMe
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
lyProAlaGlyThrGlyLysThrGluThrThrLysAspLeuGlyArgAlaLeuGlyMe
GCCCAGCTGGTACAGGGAAAACAGAAACCACCAAAGATCTGGGCCGTGCCCTTGGCAT
tMetValTyrValPheAsnCysSerGluGlnMetAspTyrLys >>>> Target I
||||||||||||||||||||||||||||||||||||||||||| 115
tMetValTyrValPheAsnCysSerGluGlnMetAspTyrLys++
GATGGTTTATGTCTTCAACTGTTCAGAGCAAATGGACTACAAAgt
ntron 33 >>>> SerIleGlyAsnIleTyrLysGlyLeuValGlnThrGlyAlaT
bp |||||||||||||||||||||||||||||||||||||||||||
++SerIleGlyAsnIleTyrLysGlyLeuValGlnThrGlyAlaT
agTCCATAGGAAATATCTATAAGGGACTGGTGCAGACAGGAGCTT
rpGlyCysPheAspGluPheAsnArgIleSerValGluValLeuSerValValAlaVa
||||||||||||||||||||||||||||| ||||||||||||||||||||||||||
rpGlyCysPheAspGluPheAsnArgIleAlaValGluValLeuSerValValAlaVa
GGGGCTGTTTTGATGAGTTCAATCGAATCGCTGTGGAAGTTCTGTCGGTGGTCGCAGT
lGlnValLysMetIleHisAspAlaIleArgAsnArgLysLys{Ar} >>>> Targ
|||||||||||||||||||||||||||||||||||||||||||{||}
lGlnValLysMetIleHisAspAlaIleArgAsnArgLysLys{Ar}++
ACAAGTGAAAATGATTCACGATGCTATCAGGAACAGGAAAAAG{AG}gt
et Intron 34 >>>> {g}PheValPheLeuGlyGluAlaIleThrLeuLysPro
3659 bp {|}||||||||||||||||||||||||||||||||||||
++{g}PheValPheLeuGlyGluAlaIleThrLeuLysPro
ag{A}TTTGTATTTCTTGGGGAAGCTATCACGCTCAAGCCA
SerValGlyIlePheIleThrMetAsnProGlyTyrAlaGlyArgThrGluLeuProG
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
SerValGlyIlePheIleThrMetAsnProGlyTyrAlaGlyArgThrGluLeuProG
TCAGTTGGAATATTTATTACCATGAACCCAGGATACGCTGGTCGAACTGAATTACCAG
luAsnLeuLysAlaLeuPhe{Ar} >>>> Target Intron 35 >>>> {g}P
||||||||||||||||||||{||} 6084 bp {|}|
luAsnLeuLysAlaLeuPhe{Ar}+- ++{g}P
AAAATCTCAAAGCTCTTTTC{AG}gc ag{A}C
roCysAlaMetValAlaProAspIleGluLeuIleCysGluIleLeuLeuValAlaGl
|||||||||||||||||||||||||||||||||||||||||||| |||||||||||
roCysAlaMetValAlaProAspIleGluLeuIleCysGluIleMetLeuValAlaGl
CCTGTGCCATGGTGGCCCCTGACATTGAGCTAATATGTGAAATCATGTTAGTTGCTGA
uGlyPheValAspAlaArgAlaLeuAlaArgLysPheIleThrLeuTyrThrLeuCys
||||||||||||||||||| ||||||||||||||||||||||||||||||||||||
uGlyPheValAspAlaArgSerLeuAlaArgLysPheIleThrLeuTyrThrLeuCys
AGGATTTGTGGATGCACGCTCTCTGGCCCGGAAATTCATTACATTGTACACGCTCTGC
LysGluLeuLeuSerLysGln >>>> Target Intron 36 >>>> AspHisT
||||||||||||||||||||| 3421 bp |||||||
LysGluLeuLeuSerLysGln++ ++AspHisT
AAAGAACTCCTCTCCAAGCAGgt agGATCATT
yrAspTrpGlyLeuArgAlaIleLysSerValLeuValValAlaGlySerLeuLysAr
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
yrAspTrpGlyLeuArgAlaIleLysSerValLeuValValAlaGlySerLeuLysAr
ATGATTGGGGACTTCGTGCTATTAAATCTGTCTTGGTTGTAGCCGGCTCTCTGAAACG
gGlyAspLysAsnArgProGluAspGln >>>> Target Intron 37 >>>>
|||||||||||||||||||||||||||| 2175 bp
gGlyAspLysAsnArgProGluAspGln++ ++
AGGAGATAAAAATAGACCTGAAGATCAGgt ag
ValLeuMetArgAlaLeuArgAspPheAsnMetProLysIleValThrAspAspIleP
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ValLeuMetArgAlaLeuArgAspPheAsnMetProLysIleValThrAspAspIleP
GTACTCATGAGAGCACTGAGGGACTTCAATATGCCTAAAATAGTGACTGACGACATCC
roValPheLeuGlyLeuValGlyAspLeuPheProAlaLeuAspValProArgArgAr
||||||||||||||||| |||||||||||||||||||||||||||||||||||
roValPheLeuGlyLeuIleSerAspLeuPheProAlaLeuAspValProArgArgAr
CAGTGTTTCTGGGCCTGATCAGTGACCTGTTTCCAGCCTTGGATGTGCCCCGGAGAAG
gLysLeuHisPheGluGlnMetValArgGlnSerThrLeuGluLeuArgLeuGlnPro
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
gLysLeuHisPheGluGlnMetValArgGlnSerThrLeuGluLeuArgLeuGlnPro
GAAACTACACTTTGAACAGATGGTCAGGCAGTCTACCCTGGAGCTCCGCCTGCAGCCT
GluGluSerPheIleLeuLys >>>> Target Intron 38 >>>> ValValG
||| ||||||||||||||| 1400 bp |||||||
GluAspSerPheIleLeuLys++ ++ValValG
GAAGATAGCTTCATCCTCAAAgt agGTTGTCC
lnLeuGluGluLeuLeuAlaValArgHisSerValPheValValGlyAsnAlaGlyTh
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
lnLeuGluGluLeuLeuAlaValArgHisSerValPheValValGlyAsnAlaGlyTh
AGCTTGAGGAGCTGTTGGCTGTGCGGCATTCTGTCTTTGTGGTTGGAAATGCGGGCAC
rGlyLysSerLys >>>> Target Intron 39 >>>> IleLeuArgThrLeu
|||||||||| 2145 bp |||||||||||||||
rGlyLysSerGln++ ++IleLeuArgThrLeu
AGGAAAGAGCCAGgt agATTTTGCGAACACTG
AsnArgThrTyrValAsnMetLysGlnLysProValTrpAsnAspLeuAsnProLysA
||| ||||||||||||||||||||||||||||||||||||||||||||||||||||
AsnGlnThrTyrValAsnMetLysGlnLysProValTrpAsnAspLeuAsnProLysA
AACCAAACATATGTTAACATGAAACAGAAACCCGTTTGGAATGACTTAAACCCTAAAG
laValThrThrAspGluLeuPheGlyPheIleHisHisAlaThrArgGluTrpLysAs
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
laValThrThrAspGluLeuPheGlyPheIleHisHisAlaThrArgGluTrpLysAs
CTGTAACAACAGATGAACTCTTTGGTTTCATACATCATGCTACCCGAGAATGGAAAGA
pGly{Ly} >>>> Target Intron 40 >>>> {s}IleValTyrSerTyrPh
||||{||} 2591 bp {|}
pGly{Ly}++ +-{s}His***AspCysLeuLe
TGGC{AA}gt at{A}CACTAGGATTGTTTACT
eIleGlyLeuPheSerSerIleLeuArgGluGlnAlaAsnLeuLysHisAspGlyPro
||||||||||||||||||||||||||||||||||||||| ||||||||||||
uValGlyLeuPheSerSerIleLeuArgGluGlnAlaAsnLeuMetHisAspGlyPro
TGTAGGTCTCTTCTCATCCATTCTGCGGGAACAAGCAAATCTTATGCATGATGGACCG
LysTrpIleValLeuAspGlyAspIleAspProMetTrpIleGluSerLeuAsnThrV
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
LysTrpIleValLeuAspGlyAspIleAspProMetTrpIleGluSerLeuAsnThrV
AAATGGATAGTGCTGGATGGAGATATTGACCCCATGTGGATTGAATCACTAAATACTG
alMetAspAspAsnLys >>>> Target Intron 41 >>>> ValLeuThrLe
||||||||||||||||| 4847 bp |||||||||||
alMetAspAspAsnLys++ ++ValLeuThrLe
TCATGGATGACAACAAGgt agGTGCTGACCCT
uAlaSerAsnGluArgIleAlaLeuThrProPheMetArgLeuLeuPheGluIleHis
|||||||||||||||| ||||||||||||||||||||||||||||||||||||
uAlaSerAsnGluArgValAlaLeuThrProPheMetArgLeuLeuPheGluIleSer
CGCCAGCAATGAGCGTGTAGCCCTCACTCCTTTCATGAGGCTCCTGTTCGAGATAAGC
HisLeuArgSerAlaThrProAlaThrValSerArgAlaGlyIleLeuTyrValAsnP
||||||||| ||||||||||||||||||||||||||||||||||||||||||||||
HisLeuArgThrAlaThrProAlaThrValSerArgAlaGlyIleLeuTyrValAsnP
CACTTGAGAACGGCAACCCCAGCGACTGTATCCAGAGCTGGTATTCTGTATGTGAACC
roGlnAspLeuGlyTrpAsn{Pr} >>>> Target Intron 42 >>>> {o}T
||||||||||||||||||||{||} 14724 bp {|}|
roGlnAspLeuGlyTrpAsn{Pr}++ ++{o}T
CACAAGATTTGGGCTGGAAT{CC}gt ag{G}T
yrValAlaSerTrpIleAspArgArgArgHisGlnSerGluLysAlaAsnLeuThrIl
|||||||||||||||||||||||||| |||||||||||||||||||||||||||||
yrValAlaSerTrpIleAspArgArgGlnHisGlnSerGluLysAlaAsnLeuThrIl
ATGTGGCCAGTTGGATAGACAGAAGGCAACATCAATCAGAAAAGGCTAATTTAACTAT
eLeuPheAspLysTyrValProAlaCysLeuAspLysLeuArgThrSerPheLysThr
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
eLeuPheAspLysTyrValProAlaCysLeuAspLysLeuArgThrSerPheLysThr
CCTTTTCGATAAATACGTCCCTGCATGTTTGGATAAGCTGAGAACAAGCTTTAAGACT
IleThrSerIleProGluSerSerLeuValGln >>>> Target Intron 43 >
||||||||||||||||||||||||||||||||| 2801 bp
IleThrSerIleProGluSerSerLeuValGln++
ATCACTTCAATTCCAGAGAGTAGCCTGGTGCAGgt
>>> ThrLeuCysValLeuLeuGluCysLeuLeuThrProGluAsnValProSerAs
|||||||||||||||||||||||||||||||||||||||||||||||||||||
++ThrLeuCysValLeuLeuGluCysLeuLeuThrProGluAsnValProSerAs
agACTCTCTGTGTTCTTTTGGAGTGTTTGTTGACTCCTGAAAATGTACCATCTGA
pSerProLysGluValTyrGluValTyrPheValPheAlaCysIleTrpAlaPheGly
||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
pSerProLysGluIleTyrGluValTyrPheValPheAlaCysIleTrpAlaPheGly
CAGCCCAAAAGAAATCTATGAAGTCTATTTTGTCTTTGCTTGTATCTGGGCCTTTGGA
GlyThrLeuLeuGlnAspGln >>>> Target Intron 44 >>>> IleSerA
||||||||||||||||||||| 4106 bp |
GlyThrLeuLeuGlnAspGln++ ++LeuPheA
GGCACCCTGCTACAAGACCAGgt agCTTTTTG
spTyrGlnAlaAspPheSerArgTrpTrpGlnLysGluMetLysAlaValLysPhePr
||||||||||||||||||||||||||||| ||||||||||||||||||||||||||
spTyrGlnAlaAspPheSerArgTrpTrpHisLysGluMetLysAlaValLysPhePr
ATTATCAAGCTGATTTCAGCCGGTGGTGGCATAAAGAGATGAAGGCGGTGAAGTTTCC
oSerGlnGlyThrIlePheAspTyrTyrValAspHisLysThrLysLysLeuLeuPro
| |||||||||||||||||||||||| |||||||||||||||||| ||||||
oPheGlnGlyThrIlePheAspTyrTyrLeuAspHisLysThrLysLysPheLeuPro
ATTCCAGGGGACAATCTTTGACTATTACTTGGACCATAAGACTAAGAAATTCTTGCCT
TrpAlaAspLysIleAlaGlnPheThrMetAspProAspValProLeuGln
|||||| |||||| |||||||||||| ||||||||||||||||||
TrpAlaGluLysIleProGlnPheThrMetGluProAspValProLeuGln
TGGGCTGAAAAAATTCCCCAGTTTACTATGGAGCCTGATGTACCTCTTCAG
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