| Basic information |
| Official Symbol | DCBLD1 |
| Description | discoidin, CUB and LCCL domain containing 1 |
| Other Aliases | RP1-94G16.1, dJ94G16.1 |
| Other Description | discoidin, CUB and LCCL domain-containing protein 1 |
| Mutation type | Insert and frame-shift 435-436:K-K^G |
| Location | Scaffold000563_1:2605226 2548511 - |
| Wiki | Wikipedia GeneCard |
| Sequence |
| DCBLD1 |
GGTGATGGCTGTGGGCACATAGTGACCTCTCAGGACAGTGGCACAGTGAC ATCTAAGAATTATCCAGGGACTTACCCCAATCACACTTTCTGTGAAAGGA CTATCACGGTACCAAAGGGGAAGAGACTAATCCTGAAGTTGGGAGATTTG GACATCGAATCCCAGACCTGTGCTTCTGACTATCTTCTCTTCACCAGCTC TTCAGATCAGTATGGTCCATATTGTGGACGTGTGACCGTTCCCAGAGAAC TCTTACTGAACACAAGTGAAGTAACCATCCGCTTTGAGAGTGGAACCCAC ATCTCTGGTCGGGGTTTTTTGCTGACCTATGCCAGCAGCGACCATCCAGA TTTAATAACGTGTTTGGAACGAGGTAACCATTATTTGAAGGCAGAATTCA GCAAATTCTGCCCAGCTGGTTGTAGAGACGTAGCAGGAGACATTTCTGGG AACATGGAAGATGGATATAGAGATACTTCTGTATTGTGCAAAGCTGCCAT CCATGCGGGGGTGATCGCAGATGAGCTGGGCGGCCAGATCAGCGTGCTGC AGCACAAAGGGATCAGCCACTACGAAGGCATCCTGGCCAATGGCGTGCTC TCCCGAGATGGCTCCCTGTCACACAAGCGATTTCTGTTCACCTCCGATGA TTGCAGCAGATCCTTGAGTTTGGAATCTGATGGGCAAATAAGAGCTTCTT CTTCTTGGCAGTGGGTCAGCGAAACAGGAGAACAAGTTCATTGGTCTCCT GACCATGCCCGCCTTCAGGACCAAGGTCTTTCGTGGGCTTCAGGAGATAG CAACAACCGCAAACGAGAATGGCTAGAGATAGATTTGGGCGAGAAAAAGA AAATAACAGGAATTAGGACTACAGGATCCACACAGTCAAATTTCAACTTT TATGTTAAGAGTTTCATGATGAGCTTCAAAAACAGCAACTCCAAGTGGAG GACCTATAAAGGAGTTACAAAAACTGAAGAAAAGGTATTTCAGGGTAACT CCAACTTTCGGGACCCAGTGCAGAACAATTTTATCCCTCCCATTGTGGCC AGATACGTGCGAGTTGTCCCCCAGACGTGGCACCAGAGGATAGCCTTGAA AGTGGAGCTCATTGGTTGCCAGATTACACAAGGTAATGATTCACTTATGT GGCACAAAACAAGTTCAAACACTGCTATTTCAACTAGAGAAGATGAGACA ATGACAAATCCTGTCTCGTCAGAAGAAATGCCCACAGGAATAAACATTAT AACCGTGGCTGTTCCACTGGTGCTCCTCGTGGTCCTGTTACTTGCCGGAA TGGGAATCTTCGCAGCCTTTAAAAAGTGGAAGAAGAAAGGAAATCCTTAT GGATCAGCTGATGCTCAGAAAATGGGCTGTTGGAAGCAAATGAAATACCC CTTTATCCGACATCACTCAGCCGAGTTTACCATCAGCTATGATAATGAGA AGGAGATGACACAAAAGTTAGATCTCATCACGAGTGACATGGCAGATTAC CAGCAGCCTCTCATGATTGGCACCGGGACAGTCACGAGGAAGGGCTCCAC CTTCCGGCCCATGGACACGGACGCGGACGCGGCTGGGACGAACGCGGAGT CTGGCGGCCACTACGACTGCCCCCCGCGCGCCGGCCTCCCAGAGTACGGC TACCGCGTCCCCGGGCCCCGGCCCGCACAC |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 715 | 38 | 600 | Insert and frame-shift 435-436:K-K^G |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
GlyAspGlyCysGlyHisLeuValThrTyrGlnAspSerGlyThrMetThrSerLysAsn
|||||||||||||||||| |||||| ||||||||||||||| ||||||||||||
GlyAspGlyCysGlyHisIleValThrSerGlnAspSerGlyThrValThrSerLysAsn
GGTGATGGCTGTGGGCACATAGTGACCTCTCAGGACAGTGGCACAGTGACATCTAAGAAT
TyrProGlyThrTyrProAsnHisThrValCysGluLysThrIleThrValProLysGly
||||||||||||||||||||||||||| |||||| |||||||||||||||||||||
TyrProGlyThrTyrProAsnHisThrPheCysGluArgThrIleThrValProLysGly
TATCCAGGGACTTACCCCAATCACACTTTCTGTGAAAGGACTATCACGGTACCAAAGGGG
LysArgLeuIleLeuArgLeuGlyAspLeuAspIleGluSerGlnThrCysAlaSerAsp
||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
LysArgLeuIleLeuLysLeuGlyAspLeuAspIleGluSerGlnThrCysAlaSerAsp
AAGAGACTAATCCTGAAGTTGGGAGATTTGGACATCGAATCCCAGACCTGTGCTTCTGAC
TyrLeuLeuPheThrSerSerSerAspGlnTyr{G} >>>> Target Intron 1 >
|||||||||||||||||||||||||||||||||{|} 21481 bp
TyrLeuLeuPheThrSerSerSerAspGlnTyr{G}++
TATCTTCTCTTCACCAGCTCTTCAGATCAGTAT{G}gt
>>> {ly}ProTyrCysGlySerMetThrValProLysGluLeuLeuLeuAsnThrSer
{||}|||||||||||| ||||||||| |||||||||||||||||||||
++{ly}ProTyrCysGlyArgValThrValProArgGluLeuLeuLeuAsnThrSer
ag{GT}CCATATTGTGGACGTGTGACCGTTCCCAGAGAACTCTTACTGAACACAAGT
GluValThrValArgPheGluSerGlySerHisIleSerGlyArgGlyPheLeuLeuThr
||||||||| ||||||||||||||| ||||||||||||||||||||||||||||||
GluValThrIleArgPheGluSerGlyThrHisIleSerGlyArgGlyPheLeuLeuThr
GAAGTAACCATCCGCTTTGAGAGTGGAACCCACATCTCTGGTCGGGGTTTTTTGCTGACC
TyrAlaSerSerAspHisPro{A} >>>> Target Intron 2 >>>> {sp}Leu
|||||||||||||||||||||{|} 1945 bp {||}|||
TyrAlaSerSerAspHisPro{A}++ ++{sp}Leu
TATGCCAGCAGCGACCATCCA{G}gt ag{AT}TTA
IleThrCysLeuGluArgAlaSerHisTyrLeuLysThrGluTyr{Se} >>>> Targ
|||||||||||||||||| |||||||||||| ||| {||}
IleThrCysLeuGluArgGlyAsnHisTyrLeuLysAlaGluPhe{Se}++
ATAACGTGTTTGGAACGAGGTAACCATTATTTGAAGGCAGAATTC{AG}gt
et Intron 3 >>>> {r}LysPheCysProAlaGlyCysArgAspValAlaGlyAsp
5670 bp {|}|||||||||||||||||||||||||||||||||||||||
++{r}LysPheCysProAlaGlyCysArgAspValAlaGlyAsp
ag{C}AAATTCTGCCCAGCTGGTTGTAGAGACGTAGCAGGAGAC
IleSerGlyAsnMetValAspGlyTyrArgAsp >>>> Target Intron 4 >>>>
||||||||||||||| ||||||||||||||| 6388 bp
IleSerGlyAsnMetGluAspGlyTyrArgAsp++
ATTTCTGGGAACATGGAAGATGGATATAGAGATgt
ThrSerLeuLeuCysLysAlaAlaIleHisAlaGlyIleIleAlaAspGluLeuGlyG
|||||| ||||||||||||||||||||||||||| |||||||||||||||||||
++ThrSerValLeuCysLysAlaAlaIleHisAlaGlyValIleAlaAspGluLeuGlyG
agACTTCTGTATTGTGCAAAGCTGCCATCCATGCGGGGGTGATCGCAGATGAGCTGGGCG
lyGlnIleSerValLeuGlnArgLysGlyIleSerArgTyrGluGlyIleLeuAlaAsnG
|||||||||||||||||||| |||||||||||| ||||||||||||||||||||||
lyGlnIleSerValLeuGlnHisLysGlyIleSerHisTyrGluGlyIleLeuAlaAsnG
GCCAGATCAGCGTGCTGCAGCACAAAGGGATCAGCCACTACGAAGGCATCCTGGCCAATG
lyValLeuSerArg{As} >>>> Target Intron 5 >>>> {p}GlySerLeuS
||||||||||||||{||} 4665 bp {|}||||||||||
lyValLeuSerArg{As}++ ++{p}GlySerLeuS
GCGTGCTCTCCCGA{GA}gt ag{T}GGCTCCCTGT
erAspLysArgPheLeuPheThrSerAsn{G} >>>> Target Intron 6 >>>>
|| ||||||||||||||||||||| { } 1573 bp
erHisLysArgPheLeuPheThrSerAsp{A}++ +
CACACAAGCGATTTCTGTTCACCTCCGAT{G}gt a
{ly}CysSerArgSerLeuSerPheGluProAspGlyGlnIleArgAlaSerSerSerT
{ }|||||||||||||||||| ||| ||||||||||||||||||||||||||||
+{sp}CysSerArgSerLeuSerLeuGluSerAspGlyGlnIleArgAlaSerSerSerT
g{AT}TGCAGCAGATCCTTGAGTTTGGAATCTGATGGGCAAATAAGAGCTTCTTCTTCTT
rpGlnSerValAsnGluSerGlyAspGlnValHisTrpSerProGlyGlnAlaArgLeuG
||||| ||| ||| ||| |||||||||||||||||| ||||||||||
rpGlnTrpValSerGluThrGlyGluGlnValHisTrpSerProAspHisAlaArgLeuG
GGCAGTGGGTCAGCGAAACAGGAGAACAAGTTCATTGGTCTCCTGACCATGCCCGCCTTC
lnAspGlnGlyProSerTrpAlaSerGlyAspSerSerAsnAsnHisLysProArgGluT
||||||||||| ||||||||||||||||||||| ||| |||||||
lnAspGlnGlyLeuSerTrpAlaSerGlyAspSer------AsnAsnArgLysArgGluT
AGGACCAAGGTCTTTCGTGGGCTTCAGGAGATAGC------AACAACCGCAAACGAGAAT
rpLeuGluIleAspLeuGlyGluLysLysLysIleThr{G} >>>> Target Intro
||||||||||||||||||||||||||||||||||||||{|} 889 bp
rpLeuGluIleAspLeuGlyGluLysLysLysIleThr{G}++
GGCTAGAGATAGATTTGGGCGAGAAAAAGAAAATAACA{G}gt
n 7 >>>> {ly}IleArgThrThrGlySerThrGlnSerAsnPheAsnPheTyrValL
{||}||||||||||||||||||||||||||||||||||||||||||||||
++{ly}IleArgThrThrGlySerThrGlnSerAsnPheAsnPheTyrValL
ag{GA}ATTAGGACTACAGGATCCACACAGTCAAATTTCAACTTTTATGTTA
ysSerPheValMetAsnPheLysAsnAsnAsnSerLysTrpLysThrTyrLysGlyIleV
|||||||| ||| ||||||||| |||||||||||| ||||||||||||
ysSerPheMetMetSerPheLysAsnSerAsnSerLysTrpArgThrTyrLysGlyValT
AGAGTTTCATGATGAGCTTCAAAAACAGCAACTCCAAGTGGAGGACCTATAAAGGAGTTA
alAsnAsnGluGluLys >>>> Target Intron 8 >>>> ValPheGlnGlyAs
||||||||| 1470 bp ||||||||||||||
hrLysThrGluGluLys++ ++ValPheGlnGlyAs
CAAAAACTGAAGAAAAGgt agGTATTTCAGGGTAA
nSerAsnPheArgAspProValGlnAsnAsnPheIleProProIleValAlaArgTyrVa
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
nSerAsnPheArgAspProValGlnAsnAsnPheIleProProIleValAlaArgTyrVa
CTCCAACTTTCGGGACCCAGTGCAGAACAATTTTATCCCTCCCATTGTGGCCAGATACGT
lArgValValProGlnThrTrpHisGlnArgIleAlaLeuLysValGluLeuIleGlyCy
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
lArgValValProGlnThrTrpHisGlnArgIleAlaLeuLysValGluLeuIleGlyCy
GCGAGTTGTCCCCCAGACGTGGCACCAGAGGATAGCCTTGAAAGTGGAGCTCATTGGTTG
sGlnIleThrGln{G} >>>> Target Intron 9 >>>> {ly}AsnAspSerLe
|||||||||||||{|} 98 bp {||}|||||||||||
sGlnIleThrGln{G}++ ++{ly}AsnAspSerLe
CCAGATTACACAA{G}gt ag{GT}AATGATTCACT
uValTrpArgLysThrSerGlnSerThrSerValSerThrLys-LysGluAspGluThrI
| ||| ||||||||| ||| |||||| # ||||||||||||
uMetTrpHisLysThrSerSerAsnThrAlaIleSerThr---#ArgGluAspGluThrM
TATGTGGCACAAAACAAGTTCAAACACTGCTATTTCAACT---GAGAGAAGATGAGACAA
leThrArgProIleProSerGluGluThrSerThr{G} >>>> Target Intron 1
||| ||| ||||||||| |||{|} 2978 bp
etThrAsnProValSerSerGluGluMetProThr{G}-+
TGACAAATCCTGTCTCGTCAGAAGAAATGCCCACA{G}at
0 >>>> {ly}IleAsnIleThrThrValAlaIleProLeuValLeuLeuValValLeu
{||}||||||||| ||||||||| ||||||||||||||||||||||||
++{ly}IleAsnIleIleThrValAlaValProLeuValLeuLeuValValLeu
ag{GA}ATAAACATTATAACCGTGGCTGTTCCACTGGTGCTCCTCGTGGTCCTG
ValPheAlaGlyMetGlyIlePheAlaAlaPheArg{Ly} >>>> Target Intron
||||||||||||||||||||||||||| {||} 2182 bp
LeuLeuAlaGlyMetGlyIlePheAlaAlaPheLys{Ly}++
TTACTTGCCGGAATGGGAATCTTCGCAGCCTTTAAA{AA}gt
11 >>>> {s}LysLysLysLysGlySerProTyrGlySerAlaGluAlaGlnLysTh
{|} |||||||||||| ||||||||||||||| |||||||||
++{s}TrpLysLysLysGlyAsnProTyrGlySerAlaAspAlaGlnLysMe
ag{G}TGGAAGAAGAAAGGAAATCCTTATGGATCAGCTGATGCTCAGAAAAT
r{A} >>>> Target Intron 12 >>>> {sp}CysTrpLysGlnIleLysTyrP
{ } 1581 bp { }|||||||||||| |||||||
t{G}++ ++{ly}CysTrpLysGlnMetLysTyrP
G{G}gt ag{GC}TGTTGGAAGCAAATGAAATACC
roPheAlaArgHisGlnSerAlaGluPheThrIleSerTyrAspAsnGluLysGluMetT
||||| |||||| |||||||||||||||||||||||||||||||||||||||||||
roPheIleArgHisHisSerAlaGluPheThrIleSerTyrAspAsnGluLysGluMetT
CCTTTATCCGACATCACTCAGCCGAGTTTACCATCAGCTATGATAATGAGAAGGAGATGA
hrGlnLysLeuAspLeuIleThrSerAspMetAla{A} >>>> Target Intron 1
|||||||||||||||||||||||||||||||||||{|} 4115 bp
hrGlnLysLeuAspLeuIleThrSerAspMetAla{A}++
CACAAAAGTTAGATCTCATCACGAGTGACATGGCA{G}gt
3 >>>> {sp}TyrGlnGlnProLeuMetIleGlyThrGlyThrValThrArgLysGly
{||}||||||||||||||||||||||||||||||||||||||||||||||||
++{sp}TyrGlnGlnProLeuMetIleGlyThrGlyThrValThrArgLysGly
ag{AT}TACCAGCAGCCTCTCATGATTGGCACCGGGACAGTCACGAGGAAGGGC
SerThrPheArgProMetAspThrAspAlaGluGluAlaGlyValSerThrAspAlaGly
|||||||||||||||||||||||||||||| |||||| |||
SerThrPheArgProMetAspThrAspAlaAspAlaAlaGlyThrAsnAlaGluSerGly
TCCACCTTCCGGCCCATGGACACGGACGCGGACGCGGCTGGGACGAACGCGGAGTCTGGC
GlyHisTyrAspCysProGlnArgAlaGlyArgHisGluTyrAlaLeuProLeuAlaPro
|||||||||||||||||| ||||||||| ||||||
GlyHisTyrAspCysProProArgAlaGlyLeuProGluTyrGlyTyrArgValProGly
GGCCACTACGACTGCCCCCCGCGCGCCGGCCTCCCAGAGTACGGCTACCGCGTCCCCGGG
ProGluProGluTyr
||| |||
ProArgProAlaHis
CCCCGGCCCGCACAC
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