| Basic information |
| Official Symbol | CLEC5A |
| Description | C-type lectin domain family 5, member A |
| Other Aliases | CLECSF5, MDL-1, MDL1 |
| Other Description | C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 5; C-type lectin domain family 5 member A; C-type lectin superfamily member 5; myeloid DAP12-associating lectin 1; myeloid DAP12-associating lectin-1 |
| Mutation type | premature termination 43:S->TGA |
| Location | Scaffold000140_1:9398877 9390834 - |
| Wiki | Wikipedia GeneCard |
| Sequence |
| CLEC5A |
ATGAACTGGCACATGATCATGTCTGGGCTTATTGTAGTAGTCCTTAAAGT TGTTGGAATGACCTTATTTCTGTTGCATTGTGAGTATTTTAGCAACCTCT TACCCCAGCTTTCTTGTCTTACTCTGTGATTCTTCTCAGTCTCACAGATT TTTGGGAGCAACTCCCCAAGTCCCATCAGCTTCGTTCCCACAAGGAGCTA TGGAACAGTCTGCCCCAAAGGTTGGGATCTTCATCAAGGAAGATGCTTTT TCTTATCCTCCTTTGAATTGTCTTGGAATAAAAGCAGGGACTCTTGTGAA GCAGAAGGATCCACTTTGGCCATTGTCAACACTCCAGAGAAACTGAAGTT TCTTCAAGTCATAACTGGAGCTGAGAAGTATTTTATTGGCTTAATGTATC AGCAGGCAGAGAAAAGGTGGCGTTGGATCAACAATGCTGTGTTCAATGGC AATGTTACCAATCAGAATCAGAATTTCAACTGTGTGACCATCGGCCTCAC AAAGACATTTGATGCCGCATCATGTGACATCAACTACCGTTGGATCTGCG AGAAGAATGCCAAA |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 188 | 1 | 188 | Premature termination 43:S->TGA |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
MetAsnTrpHisMetIleIleSerGlyLeuIleValValValLeuLysValValGlyMet
|||||||||||||||||| |||||||||||||||||||||||||||||||||||||||
MetAsnTrpHisMetIleMetSerGlyLeuIleValValValLeuLysValValGlyMet
ATGAACTGGCACATGATCATGTCTGGGCTTATTGTAGTAGTCCTTAAAGTTGTTGGAATG
ThrLeuPheLeuLeuTyrPheProGlnIlePheAsnLysSerAsnAspGlyPheThrThr
||||||||||||||| |||
ThrLeuPheLeuLeuHisCysGluTyrPheSerAsnLeuLeuProGlnLeuSerCysLeu
ACCTTATTTCTGTTGCATTGTGAGTATTTTAGCAACCTCTTACCCCAGCTTTCTTGTCTT
ThrArgSerTyrGly{T} >>>> Target Intron 1 >>>> {hr}ValSerGln
||| { } 2660 bp { }|||||||||
ThrLeu***PhePhe{S}++ --{er}ValSerGln
ACTCTGTGATTCTTC{T}gt tt{CA}GTCTCACAG
IlePheGlySerSerSerProSerProAsnGlyPheIleThrThrArgSerTyrGlyThr
|||||||||||| |||||||||||| ||| ||||||||||||||||||
IlePheGlySerAsnSerProSerProIleSerPheValProThrArgSerTyrGlyThr
ATTTTTGGGAGCAACTCCCCAAGTCCCATCAGCTTCGTTCCCACAAGGAGCTATGGAACA
{V} >>>> Target Intron 2 >>>> {al}CysProLysAspTrpGluPheTyr
{|} 1105 bp {||}||||||||| |||
{V}++ ++{al}CysProLysGlyTrpAspLeuHis
{G}gt ag{TC}TGCCCCAAAGGTTGGGATCTTCAT
GlnAlaArgCysPhePheLeuSerThrSerGluSerSerTrpAsnGluSerArgAspPhe
||| |||||||||||||||||| ||| ||||||||| |||||||||
GlnGlyArgCysPhePheLeuSerSerPheGluLeuSerTrpAsnLysSerArgAspSer
CAAGGAAGATGCTTTTTCTTATCCTCCTTTGAATTGTCTTGGAATAAAAGCAGGGACTCT
CysLysGlyLysGlySerThrLeuAlaIleValAsnThrProGluLysLeu >>>> Ta
||| |||||||||||||||||||||||||||||||||||||||
CysGluAlaGluGlySerThrLeuAlaIleValAsnThrProGluLysLeu++
TGTGAAGCAGAAGGATCCACTTTGGCCATTGTCAACACTCCAGAGAAACTGgt
rget Intron 3 >>>> LysPheLeuGlnAspIleThrAspAlaGluLysTyrPheI
1856 bp |||||||||||| |||||| ||||||||||||||||
++LysPheLeuGlnValIleThrGlyAlaGluLysTyrPheI
agAAGTTTCTTCAAGTCATAACTGGAGCTGAGAAGTATTTTA
leGlyLeuIleTyrHisArgGluGluLysArgTrpArgTrpIleAsnAsnSerValPheA
|||||||| ||| ||||||||||||||||||||||||||| |||||||
leGlyLeuMetTyrGlnGlnAlaGluLysArgTrpArgTrpIleAsnAsnAlaValPheA
TTGGCTTAATGTATCAGCAGGCAGAGAAAAGGTGGCGTTGGATCAACAATGCTGTGTTCA
snGly{As} >>>> Target Intron 4 >>>> {n}ValThrAsnGlnAsnGlnA
|||||{||} 1859 bp {|}|||||||||||||||||||
snGly{As}++ ++{n}ValThrAsnGlnAsnGlnA
ATGGC{AA}gt ag{T}GTTACCAATCAGAATCAGA
snPheAsnCysAlaThrIleGlyLeuThrLysThrPheAspAlaAlaSerCysAspIleS
||||||||||| |||||||||||||||||||||||||||||||||||||||||||||
snPheAsnCysValThrIleGlyLeuThrLysThrPheAspAlaAlaSerCysAspIleA
ATTTCAACTGTGTGACCATCGGCCTCACAAAGACATTTGATGCCGCATCATGTGACATCA
erTyrArgArgIleCysGluLysAsnAlaLys
|||||| |||||||||||||||||||||
snTyrArgTrpIleCysGluLysAsnAlaLys
ACTACCGTTGGATCTGCGAGAAGAATGCCAAA
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