| Basic information |
| Official Symbol | CCDC28A |
| Description | coiled-coil domain containing 28A |
| Other Aliases | RP3-509I19.10-001, C6orf80, CCRL1AP |
| Other Description | chemokine C-C motif receptor-like 1 adjacent; coiled-coil domain-containing protein 28A |
| Mutation type | Insert and frame-shift 27-28:L-L^C |
| Location | Scaffold000313_1:657152 670255 + |
| Wiki | Wikipedia GeneCard |
| Sequence |
| CCDC28A |
GTGCCGAGGGCGGAGACGGCAGCGACGCAGGCTGAACAGGAAGAGGCGGG GCTCCCGCCTGGCGCACGGAGGCCCCGCCTTTTACGTCACTTCCGTAAAC AAAGGCAGCTGCGGAGGCGCGGGTCCCGGGATGTGATTTGGGCCCTCGCT GCAGCAGCGGCGGTGGCTTCCGAGGCTCCCAGGTCTTTGCACGTTGACGG AGGGGACCCCCATCCCCTTCTTCCTCGGGTCCTAAGAAGCTGGCCTTGGT GCAATAAGGAACTTAAAACTATGGAGGAACGGAAAGCAAAGAGGAGGAGT CCTAAGTCTTTTAGTGCCCACTCTTCTCAAGTTGTTAATGCCAAAAAAAA TGCCATTCCAGTTAGTAAAAGCACAGGGTTTTCAAATCCTGCATCACAGT CAACTTCACAGCGGCCAAAGTTAAAAAGAGTAATGAAAGAGAAGACCAAA CCTCAGGCTGGAGAAGGAAAAGGTGCTCAATCAACTCCGATTCAGCATTC CTTCCTCACTGATGTCTCAGACGTTCAGGAGATGGAGAGGGGGCTCCTAA GTCTGCTGAACGACTTCCACTCTGGAAAACTTCAGGCATTTGGAAATGAA TGTTCCATTGAACAGATGGAACATGTTCGGGGAATGCAGGAGAAACTAGC TCGCTTGAATTTGGAGCTCTATGGGGAGTTAGAGGAACTTCCTGAGGATA AAAGAAAGACAGCTAGTGACTCCAATCTGGATAGGCTTCTGTCTGATTTA GAAGAGTTGAATTCTTCCATACAAAAACTCCACTTGGCAGATACACAAGA CGTTCCCAATACTTCTTCCAGC |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 274 | 1 | 274 | Insert and frame-shift 27-28:L-L^C |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
MetProArgAlaGluProArgAlaThrLeuGlyGluGlnGluLysAlaGlyLeuProLeu
|||||||||||| |||||| ||||||||| ||||||||||||
ValProArgAlaGluThrAlaAlaThrGlnAlaGluGlnGluGluAlaGlyLeuProPro
GTGCCGAGGGCGGAGACGGCAGCGACGCAGGCTGAACAGGAAGAGGCGGGGCTCCCGCCT
GlyAlaTrpArgLeuTyrLeu-LeuArgHisPheArgLysGlnThrGluLeuArgArgSe
|||||| ||| |||#||||||||||||||||||||| |||||||||
GlyAlaArgArgProArgLeu#LeuArgHisPheArgLysGlnArgGlnLeuArgArgAr
GGCGCACGGAGGCCCCGCCTTCTTACGTCACTTCCGTAAACAAAGGCAGCTGCGGAGGCG
rGlySerArgAspValThrGlyAlaLeuLeuValAlaAlaAlaValAlaSerGluAlaVa
||||||||||||||| |||||| ||||||||||||||||||||||||
gGlySerArgAspValIleTrpAlaLeuAlaAlaAlaAlaAlaValAlaSerGluAlaPr
CGGGTCCCGGGATGTGATTTGGGCCCTCGCTGCAGCAGCGGCGGTGGCTTCCGAGGCTCC
lGlySerLeuArgValAlaGluGlyGlyProAsnThrLeuLeuLeuGln >>>> Targ
|||||| ||| ||| ||| ||||||
oArgSerLeuHisValAspGlyGlyAspProHisProLeuLeuProArg++
CAGGTCTTTGCACGTTGACGGAGGGGACCCCCATCCCCTTCTTCCTCGGgt
et Intron 1 >>>> ValLeuArgSerTrpProTrpCysAsnLysGluLeuLysThr
1278 bp ||||||||||||||||||||||||||||||||||||||||||
++ValLeuArgSerTrpProTrpCysAsnLysGluLeuLysThr
agGTCCTAAGAAGCTGGCCTTGGTGCAATAAGGAACTTAAAACT
MetGluGluArgLysValLysArgArgSerProLysSerPheSerAlaHisCysThrGln
||||||||||||||| ||||||||||||||||||||||||||||||||| |||
MetGluGluArgLysAlaLysArgArgSerProLysSerPheSerAlaHisSerSerGln
ATGGAGGAACGGAAAGCAAAGAGGAGGAGTCCTAAGTCTTTTAGTGCCCACTCTTCTCAA
ValValAsnAlaLysLysAsnAlaIleProValSerLysSerThrGlyPheSerAsnPro
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ValValAsnAlaLysLysAsnAlaIleProValSerLysSerThrGlyPheSerAsnPro
GTTGTTAATGCCAAAAAAAATGCCATTCCAGTTAGTAAAAGCACAGGGTTTTCAAATCCT
AlaSerGlnSerThrSerGlnArgProLysLeuLys{Ar} >>>> Target Intron
||||||||||||||||||||||||||||||||||||{||} 2973 bp
AlaSerGlnSerThrSerGlnArgProLysLeuLys{Ar}++
GCATCACAGTCAACTTCACAGCGGCCAAAGTTAAAA{AG}gt
2 >>>> {g}ValMetLysGluLysThrLysProGlnGlyGlyGluGlyLysGlyAla
{|}||||||||||||||||||||||||||| ||||||||||||||||||
++{g}ValMetLysGluLysThrLysProGlnAlaGlyGluGlyLysGlyAla
ag{A}GTAATGAAAGAGAAGACCAAACCTCAGGCTGGAGAAGGAAAAGGTGCT
GlnSerThrProIleGlnHisSerPheLeuThrAspValSerAspValGlnGluMetGlu
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GlnSerThrProIleGlnHisSerPheLeuThrAspValSerAspValGlnGluMetGlu
CAATCAACTCCGATTCAGCATTCCTTCCTCACTGATGTCTCAGACGTTCAGGAGATGGAG
ArgGlyLeuLeuSerLeuLeuAsnAspPheHisSerGlyLysLeuGlnAlaPhe{G} >
||||||||||||||||||||||||||||||||||||||||||||||||||||||{|}
ArgGlyLeuLeuSerLeuLeuAsnAspPheHisSerGlyLysLeuGlnAlaPhe{G}++
AGGGGGCTCCTAAGTCTGCTGAACGACTTCCACTCTGGAAAACTTCAGGCATTT{G}gt
>>> Target Intron 3 >>>> {ly}AsnGluCysSerIleGluGlnMetGluHis
3602 bp {||}||||||||||||||||||||||||||||||
++{ly}AsnGluCysSerIleGluGlnMetGluHis
ag{GA}AATGAATGTTCCATTGAACAGATGGAACAT
ValArgGlyMetGlnGluLysLeuAlaArgLeuAsnLeuGluLeuTyrGlyGluLeuGlu
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ValArgGlyMetGlnGluLysLeuAlaArgLeuAsnLeuGluLeuTyrGlyGluLeuGlu
GTTCGGGGAATGCAGGAGAAACTAGCTCGCTTGAATTTGGAGCTCTATGGGGAGTTAGAG
GluLeuProGluAspLysArgLysThrAlaSerAspSerAsnLeuAspArgLeuLeuSer
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GluLeuProGluAspLysArgLysThrAlaSerAspSerAsnLeuAspArgLeuLeuSer
GAACTTCCTGAGGATAAAAGAAAGACAGCTAGTGACTCCAATCTGGATAGGCTTCTGTCT
Asp >>>> Target Intron 4 >>>> LeuGluGluLeuAsnSerSer{Il} >
||| 1454 bp |||||||||||||||||||||{||}
Asp++ ++LeuGluGluLeuAsnSerSer{Il}++
GATgt agTTAGAAGAGTTGAATTCTTCC{AT}gt
>>> Target Intron 5 >>>> {e}GlnLysLeuHisLeuAlaAspAlaGlnAspV
2974 bp {|}||||||||||||||||||||| |||||||
++{e}GlnLysLeuHisLeuAlaAspThrGlnAspV
ag{A}CAAAAACTCCACTTGGCAGATACACAAGACG
alProAsnThrSerAlaSer
|||||||||||||| |||
alProAsnThrSerSerSer
TTCCCAATACTTCTTCCAGC
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