| Basic information |
| Official Symbol | CABIN1 |
| Description | calcineurin binding protein 1 |
| Other Aliases | CAIN, PPP3IN |
| Other Description | calcineurin binding protein cabin 1; calcineurin inhibitor; calcineurin-binding protein cabin-1 |
| Mutation type | premature termination 1590:D->TGA, premature termination 1958:R->TGA, premature termination 2020:R->TGA, premature termination 2091:P->TGA |
| Location | Scaffold000531_1:49426 203892 + |
| Wiki | Wikipedia GeneCard |
| Sequence |
| CABIN1 |
CAGATTCGAATTGCAGCCTTAAATGCCAGTTCCACCGTTGAAGATGATCA TGAAGGAAGCTTTAAAAGTCACAAAACTCAGACGAAGGAGGCCCAGGAAG CAGAGGCTTTCGCCTTATACCACAAGGCCCTGGATCTGCAGAAACACGAC CGGTTCGAGGAGTCTGCCAAAGCCTACCACGAGCTCCTGGAGGCACGCCT GCTGAGGGAGGTGGTTTCATCAGGGGATGAGAAAGAGGGATTGAAACACC CGGGACTGATACTGAAATATTCCACGTATAAGAACCTGGCCCAGCTGGCA GCTCAGAGAGAAGATCTGGAGACGGCCATGGAGTTCTACTTGGAGGCAGT GATGCTGGACTCCACGGATGTCAACCTCTGGTATAAAATTGGACACGTGG CCTTGAGGCTCATCCGGGTCCCCCTGGCTCGCCATGCTTTTGAGGAAGGG CTGCGGTGCAATCCTGACCACTGGCCCTGCCTGGACAACCTCATCACCGT CCTGTACACCCTCAGTGATTACACAACATGTCTGTACTTCATCTGCAAAG CCTTGGAGAAGGACTGCCGGTACAGCAAGGGGCTGGTTCTCAAGGAGAAG ATCTTTGAGGAGCAGCCTTGTCTCCGTAAGGACTCTCTCCGAATGTTCCT CAAGTGTGACATGTCCATCCACGATGTGTCAGTGAGTGCCGCAGAGACAC AGGCCATCGTGGACGAGGCCCTGGGGCTGCGGAAGAAGAGGCAGGCCCTG ACCACGCGGGAGAAGGAGCCCGACCTGAAGCTGGTGCAGCCCATCCCCTT CTTCACGTGGAAGTGCCTTGGAGAGAGCTTGCTGGCCATGTACAACCACC TGACCACCTGCGAGCCCCCACGGCCCAGCCTCGGCAAGAGGATCGACCTG TCCGACTACCAGGACCCCAGCCCACCTCTCGTGTCCTCCATGGTGACGCC TGTCAGTGTGATCCAGCCCAGCCCTGTCAGCGCCAACCCAGCCGTGACCG TGGCTGAGCCCGTGGTCTCTTACGCCTCCGTGCCCACCACCAGTTTCCCG CTGCACACTCCCAGCCTGTTGGAGACTGGCACTGCAGTGGGCGACGTGTC TGGGGGTGATAAATCCAAGAAAGGAGTGAAGCGGAAGAAGATCTCGGAAG AGAGTGGGGAGACAGCAAAGCGGCGGTCTGCGCGTGTCCGGAACACCAAG TGCAAAAAGGAGGAGAAAGTAGACTTCCAGGAGCTTCTGGTGAAGTTCTT GCCGTCCCGGCTGAGAAAGCTGGACCCCGAGGAGGAAGATGACCCCTTCA ATAACTACGAAGTCCAGTCCGAGGCCAAACTGGAAAGCTTCCCGAGCATC GGGCCCCACAGGCTGTCGTTTGACTCGGCCACATTCATGGAATCGGAGAA GCAGGACGTGCACGAGTTCCTGCTGGAGAACCTGACCAACGGGGGCATCC TGGAGCTGATGATGCGCTACCTGAAGGGCATGGGCCACAAGTTCCTGCTG CGCTGGCCGCCGGGGCTGGCGGAGGTCGTGCTCAGCGTCTACCACAGCTG GAGGAGGCACAGCACCAGCCTGCCCAACCCGCTGCTGAGGGACTGCAGCA ACCAGCACATCAAGGACATGATGCTGATGTCCCTGTCCTGCATGGAGCTG CAGCTGGACCAGTGGCTGCTGACCAGAGGCAGAGGCTCTGCAGTGTCTCC TCGGAACTGCCCCACTGGTGTGGTGAATGGCAGGTTTGGGCCCGACTTCC CGGGAACCCACTGCCTGGGTGACCTCCTGCAGCTGTCCTTCGCCTCGTCT CAGCGCGACTTGTTTGAGGATGGCTGGCTGGAGTTCGTGGTCCGTGTTTA CTGGCTGAAGGCCCGCTTCCTGGCATTGCAGGGGGACATGGAGCAGGCCC TGGAGAACTACGACGTCTGCACCGAGGTGCTCCAGAGCTCCCCTGCCACG CAGGGCGAGGCCGGCACCGAGCCCAGGGGCATTGTCATCTGCCTGCCCAA CCTCCACAACGACTCCGTCGTCTCCCTGGAGGAGATCGATAAGAACCTGA AGTCGCTGGAGCGGTGCCAGTCCCTGGAGGAGATTCAGCGGCTGTACGAG GCCGGCGACTACAAGGCAGTGGTGCATCTGCTCCGCCCCACCTTGTGCAC CAGTGGGTTCGACCGGGCCAAGCACCTGGAGTTCATGACGTCCATCCCCG AGAGGCCAGCCCAGCTGCTGCTGCTGCAGGACTCCTTGCTCCGGCTGAAG GACCATCACCAGTGTTTCGAGTGCTCCGAAGTGGCTCTGAACGAGGCCGT CCAGCAGATGGTGAACTCGAGCGAGGCTGCAGCCAAGGAGGAGTGGGTGG CCACGGTGACCCAGCTGCTGCTGGGCATCGAGCAGGCGCTGTCTGCTGAC AGCAGTGGCACCATCCTGAAGGACTCGTCCTCCTCCACCGGCCTGGTCCG CCTCACCAACAACCTCATCCAGGTCATCGATTGCAGCATGGCTGTGCAGG AGGAGCCCAAGGAACCCCACGTCTCCTCGGTGCTGCCCTGGATCACCCTG CACCGCATCATCTGGCAGGAGGAGGACACCTTCCGCTCCCTCTGCCATCA GCAGCAGCTCCAGAACCCAGTGGAGGACGGGATGTCGGAGACGCCCATGC TCCCATCCTCCCTCATGCTGCTCAACACGGCCCACGAGTACCTGGGCAGG AGGTCCTGGTGCTGCAATTCCGACGGGGCTCTGCTGCGATTCTACGTGCG GGTTCTACAGAAGGAGCTCGCCGCGTCTACCTCGGAAGACACACACCCCT ACAAGGAGGAGCTGGAGACGGCCCTGGAGCAGTGCTTCTACTGCCTCTAC AGCTTCCCCAGCAAGAAGAGCAAGGCTCGGTACCTGGAGGAGCACTCGGC CCAGCAGGTGGATCTTGTGTGGGAAGATGCCCTGTTCATGTTTGAGTATT TTAAGCCCAAGACCCTTCCTGAATTTGACAGCTACAAGACCAGCACAGTG TCTGCCGACTTGGCCAACCTCCTGAAGAGGATCGCCACCATCGTGCCACG CACAGAGAGGCCGTCACTGAGCCTGGACAGAGTCTCTGCCTACATCGAGG GGACCACAGCCGAGGTGCCCTGCCTCCCAGAGGGGGCAGACCCCGCCCCT CCGGTGGTGAATGAACTCTACTACCTCCTGGCCGATTACCACTTCAAGAA CAAGGAGCAGTCCAAGGCCATCAAGTTCTACATGCACGACATCTGCATCT GCCCCAACAGGTTCGATTCCTGGGCAGGCATGGCCCTGGCCCGGGCCAGC CGCATTCAGGACAAGCTCAACTCCAACGAGCTGAAGAGCGACGGGCCCAT CTGGAAGCATGCCACGCCCGTCCTGAACTGCTTCCGGCGGGCCCTGGAGA TTGACAGCTCCAACCTGTCCCTGTGGATCGAGTACGGCACCATGTCCTAC GCCCTGCACTCGTTCGCCTCCCGCCAGCTGAAGCAATGGCGGGCAGAGCT GCCACCCGAGCTCGTGCAGCAGATGGAGAGCCGGCGCGACAGCATGCTGG AGACAGCCAGGCACTGTTTCACGTCGGCGGCCGGCTGCGAGGGAGACGGC GACGAGGAGGAGTGGCTCATCCACTACATGCTGGGCAAGGTGNNNNNNCC ACGCCGCTCCCCCCCCGTGTCCCTGCGCCACTCCCGGCAGGCCGGCCACT ACCTGCACGAGGAGGCGGCCCGCTACCCCAAGAAGATCCACTACCACAAC CCCCCCGAGCTGGCCATGGAGGCCCTGGAGGTGTACTTCCGGCTCCACGC ATCCATCCTCAAGCTCCTGGGGAAGCCCGATTCTGGGGTCGGTGCAGAGG TCCTGGTCAACTTTATGAAGGAGGCGGCAGAAGGACCCTTTGCCAGGGGC GAGGAGAAGAACACCCCCAAAGCTTCAGAAAAGGAGAAGGCCTGCCTGGT GGATGAGGACTCCCACTCTTCAGCTGGGACACTGCCGGGCCCCGGAGCCT CCCTCCCCTCCTCCTCTGGCCCAGGTCTGACATCCCCACCTTACACAGCC ACTCCGATTGACCACGATTACGTCAAATGTAAAAAACCCCACCAGCAGGC GACGCCGGACGACCGCAGCCAGGACAGCACAGCCGTGGCCCTCTCGGACT CCAGCTCAACGCAGGACTTCTTTAACGAGCCCACCAGCTCACTGGAAGGC TCACGTAAGCCTTACACAGAGAAGAGGCCGCCCGTTCTCAGTTCCCAAGG AGGACCCAGCGGCAAAGACCTGCAGGGGGCCACCGAGGAAAGAGGAAAAC CCGAGGAGTCCTTGGAGAGTACAGAAGGCTTCCGGGCTGCAGAGCAAGGT GGCCAGAAGCCCTTGGCGGAGCCCCCTGCGTCCACCTGCATGCCTGCCAA GCCCCTGGCCTCTGCACCTGGCCTGTGGGAAGGGAAGAAGAGAGGGGACC CCCCTGGGGAGCCAGCAGCCTTCCCCCAGGGGCTGCCGGCCGGTGCCGAG GAGCAGCGGCAATTCCTCACGGAGCAGTGCATCGCCTCCTTCCGCCTGTG CCTGAGCCGCTTCCCCCAGCACTACAAGAGCCTCTACCGCCTGGCCTTCC TCTACACCCACAGCAAGACCCACCGGAACCTCCAGTGGGCCCGCGACGTG TTGCTAGGCAGCAGTATCCCGTGGCAACAGCTGCAGCACATGCCGGCACA GGGGCTCTTCTGCGAGAGGAACAAGACCAATTTCTTCAACGTGAGTACTT TGCCTTGTTGATCTCTGCGCCCCCTCCCCCNNNNNNCCTGCCCCGTGAAC CGCCCCATCGTGCTGCTGCTCAAGGTGCTGGCCCAGCTGCGGGACCACAG CACGCTGCTGAAGGTGTCCTCCATGCTGCAACGGACCCCGGACCAGGGCA AGAAGTACCTGCGAGATGCCGACCGCCAGGTCCTGGCGCAGCGGGCCTTC ATCCTCACCGTGAAGGTGCTGGAGGACACGCTGAGCGAGCTTGCCGAGGG CTCAGAACGTCCGGGGCCCAAGGCCTGCAGCCTCCCCGGAGCCAGGATGA CCAGTGACATCTCACACAAGGCCAGTCCCGAGGATGGCCAGGAAGGCCTC CCCAATGCCAAGAAGCCGCCTCTGGCTGACGGCTCAGGGCCAGGGCCCGA GCCAGGGGGCAAAGGGGGCTCCCTCAACCACCGGCCTGTGGCTATGGACG CAGGAGACAGCACAGACCAGGCCGGGGAGCGGAAGGACAAAGAGAGCCCC CGGGCAGGGCCCACCGAGCCCATGGATGTGGGGGAGGCCGCTGCTCGCTG CTCAGACTTGGAGCGGACGCCATCCCTGCTGCCCGGACGCCCCCCAAGGG ACCGGGGCCCCGAGAGCCGGCCCGCGGAGCTGTCCCTGGAGGAACTGAGC ATCAGCGCCCGGCAACAGCCCACCACGCTCACACCAGCCCAGCCAGTCCC CACCCCGGCTCCCGCTACCCCCCCTGCCACGGGGACCAGGGCGGGCAGCC ACCCCGAGGAGCCACCCCCACGGCCCAGCCGCAAGAGGAAGCTCCTGGAG GACACGGAGTCGGGCAAGACGCTCCTGCTAGACGCCTACCGCGTGTGGCA GCAGGGCCAGAAAGGCGTGGCCCACGACCTGGGGCGCATCGAGAGGGTCA TGTCCGAAACCTACATGCTCATCAAGCAGGTGGACGAGGAGGCTGCGCTG GAGCAGGCCGTGAAGTTCTGCCAGGTGCACCTCGGAGCCGCCGCCCAGAG ACAGGCCTCGGGGGACACGCCTACCACCCCAAAGCACCCCAAGGACAGCC GGGAGAACTTCTTTCCTGCGGCAGCGGTCCCCACAGCCCCCGACCCCGTG CCCGCTGATGCTCTCCAGTGAACCAGCGACACCCACACCAAGCCTCGCCC CGCACTGTCTGCCACCGTCATCCCCTGTCCTCCCTCGGCGTCCGCCTCCA CCCCAGACCCATCCAAGGATCCCGGGCCTCCCCGGCCACACAGACCCGAG GCCACCCCCAGCACAGCCTCTGTGGGCCCAGGTGAGTCCTGTCCTTGAGC TCCTGGAGNNNNNNNNNNCCCCCCGCACGAGCCACGCCGCAGCCAGCAGG TGAAGACGACCCCCACAGGCCCCCCAGGAGAGCCGCACTGCTGGCCAGCC GAGACTGCCCCGCGCACAGGTGCCGAGCCCCCCAGCAGCCAGGGTAAGTT GAGTCAGGAGCAGCCCCTCCCTGCCCACAGGCTGCCCCATGGCCTGCAGC GAGGCTGAGCCCAGGTCTCCCCCACAGCTGCCAGCTCCAAGGTCCCCAGC AGTGGGAATGCTCAGGCACCCGAGGGCCACCCGGGTAAGGCAGAGCCCGG CCGCACCAAGGCACGCCTGCTGCCCAACATGCCGAAGCTGGTCATCCCCT CGGCCGCCACCAAGTTCCCGCCCGAGATCACCGTCACGCCGCCCACCCCG ACCCTGCTGTCCCCCAAAGGCAGCATCTCCGAGGAGACCAAGCAGAAGCT GAAGTCGGCCATCCTGTCTGCCCAGTCGGCCGCCAACGTGCGGAAGGAGA GCCTGTGCCAGCCAGCCCTGGAGGTCCTGGAGACGTCCAGCCAGGAGTCC TCGCTGGAGAGCGAGACGGACGAGGACGACGACTACATGGACATC |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 2220 | 1 | 2220 | Premature termination 1590:D->TGA, Premature termination 1958:R->TGA, Premature termination 2020:R->TGA, Premature termination 2091:P->TGA |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
MetIleArgIleAlaAlaLeuAsnAlaSerSerThrIleGluAspAspHisGluGlyS
||||||||||||||||||||||||||||||||| |||||||||||||||||||
GlnIleArgIleAlaAlaLeuAsnAlaSerSerThrValGluAspAspHisGluGlyS
CAGATTCGAATTGCAGCCTTAAATGCCAGTTCCACCGTTGAAGATGATCATGAAGGAA
erPheLysSerHisLysThrGlnThrLysGluAlaGln >>>> Target Intron
|||||||||||||||||||||||||||||||||||||| 1114 bp
erPheLysSerHisLysThrGlnThrLysGluAlaGln++
GCTTTAAAAGTCACAAAACTCAGACGAAGGAGGCCCAGgt
1 >>>> GluAlaGluAlaPheAlaLeuTyrHisLysAlaLeuAspLeuGlnLysH
|||||||||||||||||||||||||||||||||||||||||||||||||
++GluAlaGluAlaPheAlaLeuTyrHisLysAlaLeuAspLeuGlnLysH
agGAAGCAGAGGCTTTCGCCTTATACCACAAGGCCCTGGATCTGCAGAAAC
isAspArgPheGluGluSerAlaLysAlaTyrHisGluLeuLeuGluAlaSerLeuLe
|||||||||||||||||||||||||||||||||||||||||||||||||| |||||
isAspArgPheGluGluSerAlaLysAlaTyrHisGluLeuLeuGluAlaArgLeuLe
ACGACCGGTTCGAGGAGTCTGCCAAAGCCTACCACGAGCTCCTGGAGGCACGCCTGCT
uArgGlu >>>> Target Intron 2 >>>> AlaValSerSerGlyAspGluL
||||||| 2850 bp |||||||||||||||||||
uArgGlu++ ++ValValSerSerGlyAspGluL
GAGGGAGgt agGTGGTTTCATCAGGGGATGAGA
ysGluGlyLeuLysHisProGlyLeuIleLeuLysTyrSerThrTyrLysAsnLeuAl
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ysGluGlyLeuLysHisProGlyLeuIleLeuLysTyrSerThrTyrLysAsnLeuAl
AAGAGGGATTGAAACACCCGGGACTGATACTGAAATATTCCACGTATAAGAACCTGGC
aGlnLeuAlaAlaGlnArgGluAspLeuGluThrAlaMetGluPheTyrLeuGlu >
|||||||||||||||||||||||||||||||||||||||||||||||||||||||
aGlnLeuAlaAlaGlnArgGluAspLeuGluThrAlaMetGluPheTyrLeuGlu++
CCAGCTGGCAGCTCAGAGAGAAGATCTGGAGACGGCCATGGAGTTCTACTTGGAGgt
>>> Target Intron 3 >>>> AlaValMetLeuAspSerThrAspValAsnLe
892 bp ||||||||||||||||||||||||||||||||
++AlaValMetLeuAspSerThrAspValAsnLe
agGCAGTGATGCTGGACTCCACGGATGTCAACCT
uTrpTyrLysIleGlyHisValAlaLeuArgLeuIleArgIleProLeuAlaArgHis
|||||||||||||||||||||||||||||||||||||||| |||||||||||||||
uTrpTyrLysIleGlyHisValAlaLeuArgLeuIleArgValProLeuAlaArgHis
CTGGTATAAAATTGGACACGTGGCCTTGAGGCTCATCCGGGTCCCCCTGGCTCGCCAT
AlaPheGluGluGlyLeuArgCysAsnProAspHisTrpProCysLeuAspAsnLeuI
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
AlaPheGluGluGlyLeuArgCysAsnProAspHisTrpProCysLeuAspAsnLeuI
GCTTTTGAGGAAGGGCTGCGGTGCAATCCTGACCACTGGCCCTGCCTGGACAACCTCA
leThrValLeuTyrThrLeuSerAspTyrThr{T} >>>> Target Intron 4
||||||||||||||||||||||||||||||||{|} 9091 bp
leThrValLeuTyrThrLeuSerAspTyrThr{T}++
TCACCGTCCTGTACACCCTCAGTGATTACACA{A}gt
>>>> {hr}CysLeuTyrPheIleCysLysAlaLeuGluLysAspCysArgTyrSer
{||}||||||||||||||||||||||||||||||||||||||||||||||||
++{hr}CysLeuTyrPheIleCysLysAlaLeuGluLysAspCysArgTyrSer
ag{CA}TGTCTGTACTTCATCTGCAAAGCCTTGGAGAAGGACTGCCGGTACAGC
LysGlyLeuValLeuLysGluLysIlePheGluGluGlnProCysLeuArgLysAspS
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
LysGlyLeuValLeuLysGluLysIlePheGluGluGlnProCysLeuArgLysAspS
AAGGGGCTGGTTCTCAAGGAGAAGATCTTTGAGGAGCAGCCTTGTCTCCGTAAGGACT
erLeuArgMetPheLeuLys{Cy} >>>> Target Intron 5 >>>> {s}As
||||||||||||||||||||{||} 1232 bp {|}||
erLeuArgMetPheLeuLys{Cy}++ ++{s}As
CTCTCCGAATGTTCCTCAAG{TG}gt ag{T}GA
pMetSerIleHisAspValSerValSerAlaAlaGluThrGlnAlaIleValAspGlu
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
pMetSerIleHisAspValSerValSerAlaAlaGluThrGlnAlaIleValAspGlu
CATGTCCATCCACGATGTGTCAGTGAGTGCCGCAGAGACACAGGCCATCGTGGACGAG
AlaLeuGlyLeuArgLysLysArgGlnAlaLeuIleValArgGluLysGluProAspL
||||||||||||||||||||||||||||||||| |||||||||||||||||||
AlaLeuGlyLeuArgLysLysArgGlnAlaLeuThrThrArgGluLysGluProAspL
GCCCTGGGGCTGCGGAAGAAGAGGCAGGCCCTGACCACGCGGGAGAAGGAGCCCGACC
euLysLeuValGlnProIleProPhePhe{Th} >>>> Target Intron 6 >>
|||||||||||||||||||||||||||||{||} 5572 bp
euLysLeuValGlnProIleProPhePhe{Th}++
TGAAGCTGGTGCAGCCCATCCCCTTCTTC{AC}gt
>> {r}TrpLysCysLeuGlyGluSerLeuLeuAlaMetTyrAsnHisLeuThrThr
{|}|||||||||||||||||||||||||||||||||||||||||||||||||||
++{r}TrpLysCysLeuGlyGluSerLeuLeuAlaMetTyrAsnHisLeuThrThr
ag{G}TGGAAGTGCCTTGGAGAGAGCTTGCTGGCCATGTACAACCACCTGACCACC
CysGluProProArgProSerLeuGlyLysArgIleAspLeuSerAspTyrGlnAspP
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
CysGluProProArgProSerLeuGlyLysArgIleAspLeuSerAspTyrGlnAspP
TGCGAGCCCCCACGGCCCAGCCTCGGCAAGAGGATCGACCTGTCCGACTACCAGGACC
roSerGlnProLeuGluSerSerMetValValThrProValAsnValIleGlnProSe
||||| |||||| ||||||||| |||||||||||| ||||||||||||||
roSerProProLeuValSerSerMet---ValThrProValSerValIleGlnProSe
CCAGCCCACCTCTCGTGTCCTCCATG---GTGACGCCTGTCAGTGTGATCCAGCCCAG
rThrValSerThrAsnProAlaValAlaValAlaGluProValValSerTyrThrSer
| |||||| |||||||||||| |||||||||||||||||||||||| |||
rProValSerAlaAsnProAlaValThrValAlaGluProValValSerTyrAlaSer
CCCTGTCAGCGCCAACCCAGCCGTGACCGTGGCTGAGCCCGTGGTCTCTTACGCCTCC
ValAlaThrThrSerPheProLeuHisSerProGlyLeuLeuGluThrGlyAlaProV
||| ||||||||||||||||||||| ||| ||||||||||||||| |
ValProThrThrSerPheProLeuHisThrProSerLeuLeuGluThrGlyThrAlaV
GTGCCCACCACCAGTTTCCCGCTGCACACTCCCAGCCTGTTGGAGACTGGCACTGCAG
al{G} >>>> Target Intron 7 >>>> {ly}AspIleSerGlyGlyAspLy
||{|} 2063 bp {||}||| ||||||||||||||
al{G}++ ++{ly}AspValSerGlyGlyAspLy
TG{G}gt ag{GC}GACGTGTCTGGGGGTGATAA
sSerLysLysGlyValLysArgLysLysIleSerGluGluSerGlyGluThrAlaLys
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
sSerLysLysGlyValLysArgLysLysIleSerGluGluSerGlyGluThrAlaLys
ATCCAAGAAAGGAGTGAAGCGGAAGAAGATCTCGGAAGAGAGTGGGGAGACAGCAAAG
ArgArgSerAlaArgValArgAsnThrLysCysLysLysGluGluLysValAspPheG
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ArgArgSerAlaArgValArgAsnThrLysCysLysLysGluGluLysValAspPheG
CGGCGGTCTGCGCGTGTCCGGAACACCAAGTGCAAAAAGGAGGAGAAAGTAGACTTCC
lnGluLeuLeuMetLysPheLeuProSer{Ar} >>>> Target Intron 8 >>
||||||||||| |||||||||||||||{||} 1728 bp
lnGluLeuLeuValLysPheLeuProSer{Ar}++
AGGAGCTTCTGGTGAAGTTCTTGCCGTCC{CG}gt
>> {g}LeuArgLysLeuAspProGluGluGluAspAspSerPheAsnAsnTyrGlu
{|}||||||||||||||||||||||||||||||||| |||||||||||||||
++{g}LeuArgLysLeuAspProGluGluGluAspAspProPheAsnAsnTyrGlu
ag{G}CTGAGAAAGCTGGACCCCGAGGAGGAAGATGACCCCTTCAATAACTACGAA
ValGlnSerGluAlaLysLeuGluSerPheProSerIleGlyProGlnArgLeuSerP
||||||||||||||||||||||||||||||||||||||||||||| ||||||||||
ValGlnSerGluAlaLysLeuGluSerPheProSerIleGlyProHisArgLeuSerP
GTCCAGTCCGAGGCCAAACTGGAAAGCTTCCCGAGCATCGGGCCCCACAGGCTGTCGT
heAspSerAlaThrPheMetGluSer{G} >>>> Target Intron 9 >>>>
||||||||||||||||||||||||||{|} 825 bp
heAspSerAlaThrPheMetGluSer{G}++ ++
TTGACTCGGCCACATTCATGGAATCG{G}gt ag
{lu}LysGlnAspValHisGluPheLeuLeuGluAsnLeuThrAsnGlyGlyIleLeu
{||}||||||||||||||||||||||||||||||||||||||||||||||||||||||
{lu}LysGlnAspValHisGluPheLeuLeuGluAsnLeuThrAsnGlyGlyIleLeu
{AG}AAGCAGGACGTGCACGAGTTCCTGCTGGAGAACCTGACCAACGGGGGCATCCTG
GluLeuMetMetArgTyrLeuLysAlaMetGlyHisLysPheLeuValArgTrpProP
|||||||||||||||||||||||| |||||||||||||||||| ||||||||||
GluLeuMetMetArgTyrLeuLysGlyMetGlyHisLysPheLeuLeuArgTrpProP
GAGCTGATGATGCGCTACCTGAAGGGCATGGGCCACAAGTTCCTGCTGCGCTGGCCGC
roGlyLeuAlaGluValValLeuSerValTyrHisSerTrpArgArgHisSerThrSe
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
roGlyLeuAlaGluValValLeuSerValTyrHisSerTrpArgArgHisSerThrSe
CGGGGCTGGCGGAGGTCGTGCTCAGCGTCTACCACAGCTGGAGGAGGCACAGCACCAG
rLeuProAsnProLeuLeuArgAspCysSerAsnLysHisIleLys >>>> Targe
|||||||||||||||||||||||||||||||||| |||||||||
rLeuProAsnProLeuLeuArgAspCysSerAsnGlnHisIleLys++
CCTGCCCAACCCGCTGCTGAGGGACTGCAGCAACCAGCACATCAAGgt
t Intron 10 >>>> AspMetMetLeuMetSerLeuSerCysMetGluLeuGlnL
1394 bp ||||||||||||||||||||||||||||||||||||||||
++AspMetMetLeuMetSerLeuSerCysMetGluLeuGlnL
agGACATGATGCTGATGTCCCTGTCCTGCATGGAGCTGCAGC
euAspGlnTrpLeuLeuThrLysGlyArgSerSerAla{V} >>>> Target Int
|||||||||||||||||||| |||||| ||||||{|} 550 b
euAspGlnTrpLeuLeuThrArgGlyArgGlySerAla{V}++
TGGACCAGTGGCTGCTGACCAGAGGCAGAGGCTCTGCA{G}gt
ron 11 >>>> {al}SerProArgAsnCysProAlaGlyMetValAsnGlyArgPh
p {||}|||||||||||||||||| ||| ||||||||||||||
++{al}SerProArgAsnCysProThrGlyValValAsnGlyArgPh
ag{TG}TCTCCTCGGAACTGCCCCACTGGTGTGGTGAATGGCAGGTT
eGlyProAspPheProGlyThrHisCysLeuGlyAspLeuLeuGlnLeuSerPheAla
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
eGlyProAspPheProGlyThrHisCysLeuGlyAspLeuLeuGlnLeuSerPheAla
TGGGCCCGACTTCCCGGGAACCCACTGCCTGGGTGACCTCCTGCAGCTGTCCTTCGCC
SerSerGlnArgAspLeuPheGluAspGlyTrpLeuGluPheValValArgValTyrT
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
SerSerGlnArgAspLeuPheGluAspGlyTrpLeuGluPheValValArgValTyrT
TCGTCTCAGCGCGACTTGTTTGAGGATGGCTGGCTGGAGTTCGTGGTCCGTGTTTACT
rpLeuLysAlaArgPheLeuAlaLeuGln >>>> Target Intron 12 >>>>
||||||||||||||||||||||||||||| 1075 bp
rpLeuLysAlaArgPheLeuAlaLeuGln++ +
GGCTGAAGGCCCGCTTCCTGGCATTGCAGgt a
GlyAspMetGluGlnAlaLeuGluAsnTyrAspIleCysThrGluMetLeuGlnSer
||||||||||||||||||||||||||||||||| ||||||||| |||||||||
+GlyAspMetGluGlnAlaLeuGluAsnTyrAspValCysThrGluValLeuGlnSer
gGGGGACATGGAGCAGGCCCTGGAGAACTACGACGTCTGCACCGAGGTGCTCCAGAGC
SerThrAlaIleGlnValGluAlaGlyAlaGluArgArgAspIleValIleArgLeuP
||| ||| ||| ||||||||| ||| ||| ||||||||| ||||
SerProAlaThrGlnGlyGluAlaGlyThrGluProArgGlyIleValIleCysLeuP
TCCCCTGCCACGCAGGGCGAGGCCGGCACCGAGCCCAGGGGCATTGTCATCTGCCTGC
roAsnLeuHisAsnAspSerValValSerLeuGluGlu >>>> Target Intron
|||||||||||||||||||||||||||||||||||||| 931 bp
roAsnLeuHisAsnAspSerValValSerLeuGluGlu++
CCAACCTCCACAACGACTCCGTCGTCTCCCTGGAGGAGgt
13 >>>> IleAspLysAsnLeuLysSerLeuGluArgCysGlnSerLeuGluGlu
||||||||||||||||||||||||||||||||||||||||||||||||
++IleAspLysAsnLeuLysSerLeuGluArgCysGlnSerLeuGluGlu
agATCGATAAGAACCTGAAGTCGCTGGAGCGGTGCCAGTCCCTGGAGGAG
IleGlnArgLeuTyrGluAlaGlyAspTyrLysAlaValValHisLeuLeuArgProT
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
IleGlnArgLeuTyrGluAlaGlyAspTyrLysAlaValValHisLeuLeuArgProT
ATTCAGCGGCTGTACGAGGCCGGCGACTACAAGGCAGTGGTGCATCTGCTCCGCCCCA
hrLeuCysThrSerGlyPheAspArgAlaLysHisLeuGluPheMetThrSerIlePr
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hrLeuCysThrSerGlyPheAspArgAlaLysHisLeuGluPheMetThrSerIlePr
CCTTGTGCACCAGTGGGTTCGACCGGGCCAAGCACCTGGAGTTCATGACGTCCATCCC
oGluArgProAlaGlnLeuLeuLeuLeuGln >>>> Target Intron 14 >>>
||||||||||||||||||||||||||||||| 6457 bp
oGluArgProAlaGlnLeuLeuLeuLeuGln++
CGAGAGGCCAGCCCAGCTGCTGCTGCTGCAGgt
> AspSerLeuLeuArgLeuLysAspTyrArgGlnCysPheGluCysSerAspValA
|||||||||||||||||||||||| |||||||||||||||||| ||||
++AspSerLeuLeuArgLeuLysAspHisHisGlnCysPheGluCysSerGluValA
agGACTCCTTGCTCCGGCTGAAGGACCATCACCAGTGTTTCGAGTGCTCCGAAGTGG
laLeuAsnGluAlaValGlnGlnMetValAsnSerGlyGluAlaAlaAlaLysGluGl
||||||||||||||||||||||||||||||||||| ||||||||||||||||||||
laLeuAsnGluAlaValGlnGlnMetValAsnSerSerGluAlaAlaAlaLysGluGl
CTCTGAACGAGGCCGTCCAGCAGATGGTGAACTCGAGCGAGGCTGCAGCCAAGGAGGA
uTrpValAlaThrValThrGlnLeuLeuMetGlyIleGluGlnAlaLeuSerAlaAsp
|||||||||||||||||||||||||||| |||||||||||||||||||||||||||
uTrpValAlaThrValThrGlnLeuLeuLeuGlyIleGluGlnAlaLeuSerAlaAsp
GTGGGTGGCCACGGTGACCCAGCTGCTGCTGGGCATCGAGCAGGCGCTGTCTGCTGAC
SerSerGlySerIleLeuLysValSerSerSerThrThrGlyLeuValArgLeuThrA
||||||||| ||||||||| ||||||||| ||||||||||||||||||||||
SerSerGlyThrIleLeuLysAspSerSerSerSerThrGlyLeuValArgLeuThrA
AGCAGTGGCACCATCCTGAAGGACTCGTCCTCCTCCACCGGCCTGGTCCGCCTCACCA
snAsnLeuIleGln >>>> Target Intron 15 >>>> ValIleAspCysSe
|||||||||||||| 647 bp ||||||||||||||
snAsnLeuIleGln++ ++ValIleAspCysSe
ACAACCTCATCCAGgt agGTCATCGATTGCAG
rMetAlaValGlnGluGluAlaLysGluProHisValSerSerValLeuProTrpIle
||||||||||||||||||| ||||||||||||||||||||||||||||||||||||
rMetAlaValGlnGluGluProLysGluProHisValSerSerValLeuProTrpIle
CATGGCTGTGCAGGAGGAGCCCAAGGAACCCCACGTCTCCTCGGTGCTGCCCTGGATC
IleLeuHisArgIleIleTrpGlnGluGluAspThrPheHisSerLeuCysHisGlnG
|||||||||||||||||||||||||||||||||||| ||||||||||||||||
ThrLeuHisArgIleIleTrpGlnGluGluAspThrPheArgSerLeuCysHisGlnG
ACCCTGCACCGCATCATCTGGCAGGAGGAGGACACCTTCCGCTCCCTCTGCCATCAGC
lnGlnLeuGlnAsnProAlaGluGlu{G} >>>> Target Intron 16 >>>>
||||||||||||||||| ||| {|} 2739 bp
lnGlnLeuGlnAsnProValGluAsp{G}++ +
AGCAGCTCCAGAACCCAGTGGAGGAC{G}gt a
{ly}MetSerGluThrProMetLeuProSerSerLeuMetLeuLeuAsnThrAlaHi
{||}|||||||||||||||||||||||||||||||||||||||||||||||||||||
+{ly}MetSerGluThrProMetLeuProSerSerLeuMetLeuLeuAsnThrAlaHi
g{GG}ATGTCGGAGACGCCCATGCTCCCATCCTCCCTCATGCTGCTCAACACGGCCCA
sGluTyrLeuGlyArgArgSerTrpCysCysAsnSerAspGlyAlaLeuLeuArgPhe
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
sGluTyrLeuGlyArgArgSerTrpCysCysAsnSerAspGlyAlaLeuLeuArgPhe
CGAGTACCTGGGCAGGAGGTCCTGGTGCTGCAATTCCGACGGGGCTCTGCTGCGATTC
Tyr >>>> Target Intron 17 >>>> ValArgValLeuGlnLysGluLeuA
||| 3649 bp |||||||||||||||||||||||||
Tyr++ ++ValArgValLeuGlnLysGluLeuA
TACgt agGTGCGGGTTCTACAGAAGGAGCTCG
laAlaSerThrSerGluAspThrHisProTyrLysGluGluLeuGluThrAlaLeuGl
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
laAlaSerThrSerGluAspThrHisProTyrLysGluGluLeuGluThrAlaLeuGl
CCGCGTCTACCTCGGAAGACACACACCCCTACAAGGAGGAGCTGGAGACGGCCCTGGA
uGlnCysPheTyrCysLeuTyrSerPheProSerLysLysSerLysAlaArgTyrLeu
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
uGlnCysPheTyrCysLeuTyrSerPheProSerLysLysSerLysAlaArgTyrLeu
GCAGTGCTTCTACTGCCTCTACAGCTTCCCCAGCAAGAAGAGCAAGGCTCGGTACCTG
GluGluHisSerAlaGlnGln >>>> Target Intron 18 >>>> ValAspL
||||||||||||||||||||| 1002 bp |||||||
GluGluHisSerAlaGlnGln++ ++ValAspL
GAGGAGCACTCGGCCCAGCAGgt agGTGGATC
euIleTrpGluAspAlaLeuPheMetPheGluTyrPheLysProLysThrLeuProGl
|| |||||||||||||||||||||||||||||||||||||||||||||||||||||
euValTrpGluAspAlaLeuPheMetPheGluTyrPheLysProLysThrLeuProGl
TTGTGTGGGAAGATGCCCTGTTCATGTTTGAGTATTTTAAGCCCAAGACCCTTCCTGA
uPheAspSerTyrLysThrSerThrValSerAlaAspLeuAlaAsnLeuLeuLysArg
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
uPheAspSerTyrLysThrSerThrValSerAlaAspLeuAlaAsnLeuLeuLysArg
ATTTGACAGCTACAAGACCAGCACAGTGTCTGCCGACTTGGCCAACCTCCTGAAGAGG
IleAlaThrIleValProArgThrGluArgProAlaLeuSerLeuAspLysValSerA
||||||||||||||||||||||||||||||||| |||||||||||| |||||||
IleAlaThrIleValProArgThrGluArgProSerLeuSerLeuAspArgValSerA
ATCGCCACCATCGTGCCACGCACAGAGAGGCCGTCACTGAGCCTGGACAGAGTCTCTG
laTyrIleGluGlyThrSerThrGlu >>>> Target Intron 19 >>>> Va
||||||||||||||||| ||| 159 bp ||
laTyrIleGluGlyThrThrAlaGlu++ ++Va
CCTACATCGAGGGGACCACAGCCGAGgt agGT
lProCysLeuProGluGlyAlaAspProSerProProValValAsnGluLeuTyrTyr
|||||||||||||||||||||||||||| |||||||||||||||||||||||||||
lProCysLeuProGluGlyAlaAspProAlaProProValValAsnGluLeuTyrTyr
GCCCTGCCTCCCAGAGGGGGCAGACCCCGCCCCTCCGGTGGTGAATGAACTCTACTAC
LeuLeuAlaAspTyrHisPheLysAsnLysGluGlnSerLysAlaIleLysPheTyrM
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
LeuLeuAlaAspTyrHisPheLysAsnLysGluGlnSerLysAlaIleLysPheTyrM
CTCCTGGCCGATTACCACTTCAAGAACAAGGAGCAGTCCAAGGCCATCAAGTTCTACA
etHisAspIleCysIleCysProAsn{Ar} >>>> Target Intron 20 >>>>
||||||||||||||||||||||||||{||} 3527 bp
etHisAspIleCysIleCysProAsn{Ar}++
TGCACGACATCTGCATCTGCCCCAAC{AG}gt
{g}PheAspSerTrpAlaGlyMetAlaLeuAlaArgAlaSerArgIleGlnAspLy
{|}|||||||||||||||||||||||||||||||||||||||||||||||||||||
++{g}PheAspSerTrpAlaGlyMetAlaLeuAlaArgAlaSerArgIleGlnAspLy
ag{G}TTCGATTCCTGGGCAGGCATGGCCCTGGCCCGGGCCAGCCGCATTCAGGACAA
sLeuAsnSerAsnGluLeuLysSerAspGlyProIleTrpLysHisAlaThrProVal
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
sLeuAsnSerAsnGluLeuLysSerAspGlyProIleTrpLysHisAlaThrProVal
GCTCAACTCCAACGAGCTGAAGAGCGACGGGCCCATCTGGAAGCATGCCACGCCCGTC
LeuAsnCysPheArgArgAlaLeuGluIleAspSerSerAsnLeuSerLeuTrpIleG
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
LeuAsnCysPheArgArgAlaLeuGluIleAspSerSerAsnLeuSerLeuTrpIleG
CTGAACTGCTTCCGGCGGGCCCTGGAGATTGACAGCTCCAACCTGTCCCTGTGGATCG
luTyrGlyThrMetSerTyrAlaLeuHisSerPheAlaSerArgGlnLeuLysGlnTr
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
luTyrGlyThrMetSerTyrAlaLeuHisSerPheAlaSerArgGlnLeuLysGlnTr
AGTACGGCACCATGTCCTACGCCCTGCACTCGTTCGCCTCCCGCCAGCTGAAGCAATG
pArgGlyGluLeuProProGluLeuValGlnGln >>>> Target Intron 21
|||| ||||||||||||||||||||||||||| 2423 bp
pArgAlaGluLeuProProGluLeuValGlnGln++
GCGGGCAGAGCTGCCACCCGAGCTCGTGCAGCAGgt
>>>> MetGluGlyArgArgAspSerMetLeuGluThrAlaLysHisCysPheThrS
|||||| ||||||||||||||||||||||||||| |||||||||||||
++MetGluSerArgArgAspSerMetLeuGluThrAlaArgHisCysPheThrS
agATGGAGAGCCGGCGCGACAGCATGCTGGAGACAGCCAGGCACTGTTTCACGT
erAlaAlaArgCysGluGlyAspGlyAspGluGluGluTrpLeuIleHisTyrMetLe
|||||||| |||||||||||||||||||||||||||||||||||||||||||||||
erAlaAlaGlyCysGluGlyAspGlyAspGluGluGluTrpLeuIleHisTyrMetLe
CGGCGGCCGGCTGCGAGGGAGACGGCGACGAGGAGGAGTGGCTCATCCACTACATGCT
uGlyLysValAla{G} >>>> Target Intron 22 >>>> {lu}LysGlnGl
|||||||||| { } 31 bp { }
uGlyLysValUnk{U}-- --{nk}ProArgAr
GGGCAAGGTGNNN{N}nn nn{NN}CCACGCCG
nGlnProProThrValTyrLeuLeuHisTyrArgGlnAlaGlyHisTyrLeuHisGlu
|||||| ||| ||| ||| |||||||||||||||||||||||||||
gSerProPro---ValSerLeuArgHisSerArgGlnAlaGlyHisTyrLeuHisGlu
CTCCCCCCCC---GTGTCCCTGCGCCACTCCCGGCAGGCCGGCCACTACCTGCACGAG
GluAlaAlaArgTyrProLysLysIleHisTyrHisAsnProProGluLeuAlaMetG
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GluAlaAlaArgTyrProLysLysIleHisTyrHisAsnProProGluLeuAlaMetG
GAGGCGGCCCGCTACCCCAAGAAGATCCACTACCACAACCCCCCCGAGCTGGCCATGG
luAlaLeuGlu >>>> Target Intron 23 >>>> ValTyrPheArgLeuHi
||||||||||| 3088 bp |||||||||||||||||
luAlaLeuGlu++ ++ValTyrPheArgLeuHi
AGGCCCTGGAGgt agGTGTACTTCCGGCTCCA
sAlaSerIleLeuLysLeuLeuGlyLysProAspSerGlyValGlyAlaGluValLeu
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
sAlaSerIleLeuLysLeuLeuGlyLysProAspSerGlyValGlyAlaGluValLeu
CGCATCCATCCTCAAGCTCCTGGGGAAGCCCGATTCTGGGGTCGGTGCAGAGGTCCTG
ValAsnPheMetLysGluAlaAlaGluGlyProPheAlaArgGlyGluGluLysAsnT
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ValAsnPheMetLysGluAlaAlaGluGlyProPheAlaArgGlyGluGluLysAsnT
GTCAACTTTATGAAGGAGGCGGCAGAAGGACCCTTTGCCAGGGGCGAGGAGAAGAACA
hrProLysAlaSerGlu{Ly} >>>> Target Intron 24 >>>> {s}GluL
|||||||||||||||||{||} 2492 bp {|}||||
hrProLysAlaSerGlu{Ly}++ ++{s}GluL
CCCCCAAAGCTTCAGAA{AA}gt ag{G}GAGA
ysAlaCysLeuValAspGluAspSerHisSerSerAlaGlyThrLeuProGlyProGl
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ysAlaCysLeuValAspGluAspSerHisSerSerAlaGlyThrLeuProGlyProGl
AGGCCTGCCTGGTGGATGAGGACTCCCACTCTTCAGCTGGGACACTGCCGGGCCCCGG
yAlaSerLeuProSerSerSerGlyProGlyLeuThrSerProProTyrThrAlaThr
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
yAlaSerLeuProSerSerSerGlyProGlyLeuThrSerProProTyrThrAlaThr
AGCCTCCCTCCCCTCCTCCTCTGGCCCAGGTCTGACATCCCCACCTTACACAGCCACT
ProIleAspHisAspTyrValLysCysLysLysProHisGlnGlnAlaThrProAsp{
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||{
ProIleAspHisAspTyrValLysCysLysLysProHisGlnGlnAlaThrProAsp{
CCGATTGACCACGATTACGTCAAATGTAAAAAACCCCACCAGCAGGCGACGCCGGAC{
A} >>>> Target Intron 25 >>>> {sp}ArgSerGlnAspSerThrAlaV
|} 15069 bp {||}||||||||||||||||||||||
A}++ ++{sp}ArgSerGlnAspSerThrAlaV
G}gt ag{AC}CGCAGCCAGGACAGCACAGCCG
alAlaLeuSerAspSerSerSerThrGlnAspPhePheAsnGluProThrSerLeuLe
||||||||||||||||||||||||||||||||||||||||||||||||||||| ||
alAlaLeuSerAspSerSerSerThrGlnAspPhePheAsnGluProThrSerSerLe
TGGCCCTCTCGGACTCCAGCTCAACGCAGGACTTCTTTAACGAGCCCACCAGCTCACT
uGluGlySerArgLysSerTyrThrGluLysArgLeuProIleLeuSerSerGlnAla
|||||||||||||||| ||||||||||||||| ||| ||||||||||||
uGluGlySerArgLysProTyrThrGluLysArgProProValLeuSerSerGlnGly
GGAAGGCTCACGTAAGCCTTACACAGAGAAGAGGCCGCCCGTTCTCAGTTCCCAAGGA
GlyAlaThrGlyLysAspLeuGlnGlyAlaThrGluGluArg{G} >>>> Target
||| |||||||||||||||||||||||||||||||||{|} 5
GlyProSerGlyLysAspLeuGlnGlyAlaThrGluGluArg{G}++
GGACCCAGCGGCAAAGACCTGCAGGGGGCCACCGAGGAAAGA{G}gt
Intron 26 >>>> {ly}LysAsnGluGluSerLeuGluSerThrGluGlyPheA
361 bp {||}||| |||||||||||||||||||||||||||||||
-+{ly}LysProGluGluSerLeuGluSerThrGluGlyPheA
tg{GA}AAACCCGAGGAGTCCTTGGAGAGTACAGAAGGCTTCC
rgAlaAlaGluGlnGlyValGlnLysProAlaAlaGluThrProAlaSerAlaCysIl
||||||||||||||||| ||||||||| |||||| ||||||||| |||
rgAlaAlaGluGlnGlyGlyGlnLysProLeuAlaGluProProAlaSerThrCysMe
GGGCTGCAGAGCAAGGTGGCCAGAAGCCCTTGGCGGAGCCCCCTGCGTCCACCTGCAT
eProGlyLysProSerAlaSerThrProThrLeuTrpAspGlyLysLysArgGlyAsp
||| |||||| |||||| ||| |||||| ||||||||||||||||||
tProAlaLysProLeuAlaSerAlaProGlyLeuTrpGluGlyLysLysArgGlyAsp
GCCTGCCAAGCCCCTGGCCTCTGCACCTGGCCTGTGGGAAGGGAAGAAGAGAGGGGAC
LeuProGlyGluProValAlaPheProGlnGlyLeuProAlaGlyAlaGluGluGlnA
|||||||||||| ||||||||||||||||||||||||||||||||||||||||
ProProGlyGluProAlaAlaPheProGlnGlyLeuProAlaGlyAlaGluGluGlnA
CCCCCTGGGGAGCCAGCAGCCTTCCCCCAGGGGCTGCCGGCCGGTGCCGAGGAGCAGC
rgGlnPheLeuThrGluGlnCysIleAlaSerPheArgLeuCysLeuSerArgPhePr
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
rgGlnPheLeuThrGluGlnCysIleAlaSerPheArgLeuCysLeuSerArgPhePr
GGCAATTCCTCACGGAGCAGTGCATCGCCTCCTTCCGCCTGTGCCTGAGCCGCTTCCC
oGlnHisTyrLysSerLeuTyrArgLeuAlaPheLeuTyrThrTyrSerLysThrHis
||||||||||||||||||||||||||||||||||||||||||| ||||||||||||
oGlnHisTyrLysSerLeuTyrArgLeuAlaPheLeuTyrThrHisSerLysThrHis
CCAGCACTACAAGAGCCTCTACCGCCTGGCCTTCCTCTACACCCACAGCAAGACCCAC
Arg >>>> Target Intron 27 >>>> AsnLeuGlnTrpAlaArgAspValL
||| 14368 bp |||||||||||||||||||||||||
Arg++ ++AsnLeuGlnTrpAlaArgAspValL
CGGgt agAACCTCCAGTGGGCCCGCGACGTGT
euLeuGlySerSerIleProTrpGlnGlnLeuGlnHisMetProAlaGlnGlyLeuPh
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
euLeuGlySerSerIleProTrpGlnGlnLeuGlnHisMetProAlaGlnGlyLeuPh
TGCTAGGCAGCAGTATCCCGTGGCAACAGCTGCAGCACATGCCGGCACAGGGGCTCTT
eCysGluArgAsnLysThrAsnPhePheAsnGlyIleTrpArgIleProValAspGlu
||||||||||||||||||||||||||||||| |||
eCysGluArgAsnLysThrAsnPhePheAsn---ValSerThrLeuProCys***Ser
CTGCGAGAGGAACAAGACCAATTTCTTCAAC---GTGAGTACTTTGCCTTGTTGATCT
Ile{A} >>>> Target Intron 28 >>>> {sp}ArgProGlySerPheAla
{ } 42932 bp { }
Leu{A}+- -+{rg}ProLeuProUnkUnkUnk
CTG{C}gg gg{GC}CCCCTCCCCCNNNNNNCC
TrpHisMetAsnArgSerIleValLeuLeuLeuLysValLeuAlaGlnLeuArgAspH
|||||| ||||||||||||||||||||||||||||||||||||||||
CysProValAsnArgProIleValLeuLeuLeuLysValLeuAlaGlnLeuArgAspH
TGCCCCGTGAACCGCCCCATCGTGCTGCTGCTCAAGGTGCTGGCCCAGCTGCGGGACC
isSerThrLeuLeuLysValSerSerMetLeuGlnArgThrProAspGlnGly{Ly}
|||||||||||||||||||||||||||||||||||||||||||||||||||||{||}
isSerThrLeuLeuLysValSerSerMetLeuGlnArgThrProAspGlnGly{Ly}+
ACAGCACGCTGCTGAAGGTGTCCTCCATGCTGCAACGGACCCCGGACCAGGGC{AA}g
>>>> Target Intron 29 >>>> {s}LysTyrLeuArgAspAlaAspArgGl
897 bp {|}||||||||||||||||||||||||||
+ ++{s}LysTyrLeuArgAspAlaAspArgGl
t ag{G}AAGTACCTGCGAGATGCCGACCGCCA
nValLeuAlaGlnArgAlaPheIleLeuThrValLysValLeuGluAspThrLeuSer
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
nValLeuAlaGlnArgAlaPheIleLeuThrValLysValLeuGluAspThrLeuSer
GGTCCTGGCGCAGCGGGCCTTCATCCTCACCGTGAAGGTGCTGGAGGACACGCTGAGC
GluLeuAlaGlu >>>> Target Intron 30 >>>> GlySerGluArgProG
|||||||||||| 854 bp ||||||||||||||||
GluLeuAlaGlu++ ++GlySerGluArgProG
GAGCTTGCCGAGgt agGGCTCAGAACGTCCGG
lyProLysValCysGlyLeuProGlyAlaArgMetThrThrAspValSerHisLysAl
|||||||| ||| ||||||||||||||||||||| ||| |||||||||||
lyProLysAlaCysSerLeuProGlyAlaArgMetThrSerAspIleSerHisLysAl
GGCCCAAGGCCTGCAGCCTCCCCGGAGCCAGGATGACCAGTGACATCTCACACAAGGC
aSerProGluAspGlyGlnGluGlyLeuProGlnProLysLysProProLeuAlaAsp
||||||||||||||||||||||||||||||| |||||||||||||||||||||
aSerProGluAspGlyGlnGluGlyLeuProAsnAlaLysLysProProLeuAlaAsp
CAGTCCCGAGGATGGCCAGGAAGGCCTCCCCAATGCCAAGAAGCCGCCTCTGGCTGAC
GlySerGlyProGlyProGluProGlyGlyLysValGlyLeuLeuAsnHisArgProV
||||||||||||||||||||||||||||||||| ||| ||||||||||||||||
GlySerGlyProGlyProGluProGlyGlyLysGlyGlySerLeuAsnHisArgProV
GGCTCAGGGCCAGGGCCCGAGCCAGGGGGCAAAGGGGGCTCCCTCAACCACCGGCCTG
alAlaMetAspAlaGlyAspSerAlaAspGlnSerGlyGluArgLysAspLysGluSe
||||||||||||||||||||||| |||||| |||||||||||||||||||||||
alAlaMetAspAlaGlyAspSerThrAspGlnAlaGlyGluArgLysAspLysGluSe
TGGCTATGGACGCAGGAGACAGCACAGACCAGGCCGGGGAGCGGAAGGACAAAGAGAG
rProArgAlaGlyProThrGluProMetAspThrSerGluAlaThrValCysHisSer
||||||||||||||||||||||||||||||| |||||| |||
rProArgAlaGlyProThrGluProMetAspValGlyGluAlaAlaAlaArgCysSer
CCCCCGGGCAGGGCCCACCGAGCCCATGGATGTGGGGGAGGCCGCTGCTCGCTGCTCA
AspLeuGluArgThrProProLeuLeuProGlyArgProAlaArgAspArgGlyProG
|||||||||||||||||| |||||||||||||||||| ||||||||||||||||
AspLeuGluArgThrProSerLeuLeuProGlyArgProProArgAspArgGlyProG
GACTTGGAGCGGACGCCATCCCTGCTGCCCGGACGCCCCCCAAGGGACCGGGGCCCCG
luSerArgProThrGluLeuSerLeuGluGluLeuSerIleSerAlaArgGlnGlnPr
||||||||||| ||||||||||||||||||||||||||||||||||||||||||||
luSerArgProAlaGluLeuSerLeuGluGluLeuSerIleSerAlaArgGlnGlnPr
AGAGCCGGCCCGCGGAGCTGTCCCTGGAGGAACTGAGCATCAGCGCCCGGCAACAGCC
oThrProLeuThrProAlaGlnProAlaProAlaProAlaProAlaThr<-><->Thr
|||| |||||||||||||||||| ||| |||||||||||||||
oThrThrLeuThrProAlaGlnProValProThrProAlaProAlaThrProProAla
CACCACGCTCACACCAGCCCAGCCAGTCCCCACCCCGGCTCCCGCTACCCCCCCTGCC
ThrGlyThrArgAlaGlyGlyHisProGluGluProLeuSerArgLeuSerArgLysA
|||||||||||||||||| ||||||||||||||| ||| ||||||||||
ThrGlyThrArgAlaGlySerHisProGluGluProProProArgProSerArgLysA
ACGGGGACCAGGGCGGGCAGCCACCCCGAGGAGCCACCCCCACGGCCCAGCCGCAAGA
rgLysLeuLeuGluAspThrGluSerGlyLysThrLeuLeuLeuAspAlaTyrArgVa
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
rgLysLeuLeuGluAspThrGluSerGlyLysThrLeuLeuLeuAspAlaTyrArgVa
GGAAGCTCCTGGAGGACACGGAGTCGGGCAAGACGCTCCTGCTAGACGCCTACCGCGT
lTrpGlnGlnGlyGlnLysGlyValAlaTyrAspLeuGlyArgValGluArgIleMet
|||||||||||||||||||||||||||| |||||||||||| |||||| |||
lTrpGlnGlnGlyGlnLysGlyValAlaHisAspLeuGlyArgIleGluArgValMet
GTGGCAGCAGGGCCAGAAAGGCGTGGCCCACGACCTGGGGCGCATCGAGAGGGTCATG
SerGluThrTyrMetLeuIleLysGln >>>> Target Intron 31 >>>> V
||||||||||||||||||||||||||| 3481 bp |
SerGluThrTyrMetLeuIleLysGln++ ++V
TCCGAAACCTACATGCTCATCAAGCAGgt agG
alAspGluGluAlaAlaLeuGluGlnAlaValLysPheCysGlnValHisLeuGlyAl
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
alAspGluGluAlaAlaLeuGluGlnAlaValLysPheCysGlnValHisLeuGlyAl
TGGACGAGGAGGCTGCGCTGGAGCAGGCCGTGAAGTTCTGCCAGGTGCACCTCGGAGC
aAlaAlaGlnArgGln >>>> Target Intron 32 >>>> AlaSerGlyAsp
|||||||||||||||| 2942 bp ||||||||||||
aAlaAlaGlnArgGln++ ++AlaSerGlyAsp
CGCCGCCCAGAGACAGgt agGCCTCGGGGGAC
ThrProThrThrProLysHisProLysAspSerArgGluAsnPhePheProValThrV
|||||||||||||||||||||||||||||||||||||||||||||||||||
ThrProThrThrProLysHisProLysAspSerArgGluAsnPhePheProAlaAlaA
ACGCCTACCACCCCAAAGCACCCCAAGGACAGCCGGGAGAACTTCTTTCCTGCGGCAG
alValProThrAlaProAspProValProAlaAspSerValGlnArgProSerAspAl
||||||||||||||||||||||||||||||||| ||| ||||||
laValProThrAlaProAspProValProAlaAspAlaLeuGln***ThrSerAspTh
CGGTCCCCACAGCCCCCGACCCCGTGCCCGCTGATGCTCTCCAGTGAACCAGCGACAC
aHisThrLysProArgProAlaLeuAlaAlaAlaThrThrIleIleThrCysProPro
|||||||||||||||||||||||| ||| ||| ||| |||||||||
rHisThrLysProArgProAlaLeuSerAla------ThrValIleProCysProPro
CCACACCAAGCCTCGCCCCGCACTGTCTGCC------ACCGTCATCCCCTGTCCTCCC
SerAlaSerAlaSerThrLeuAspGlnSerLysAspProGlyProProArgProHisA
|||||||||||||||||| ||| |||||||||||||||||||||||||||||||
SerAlaSerAlaSerThrProAspProSerLysAspProGlyProProArgProHisA
TCGGCGTCCGCCTCCACCCCAGACCCATCCAAGGATCCCGGGCCTCCCCGGCCACACA
rgProGluAlaThrProSerMetAlaSerLeuGlyProGluGlyGluGluLeuAlaAr
|||||||||||||||||||| |||||| |||||| ||||||
rgProGluAlaThrProSerThrAlaSerValGlyPro---GlyGluSerCysPro**
GACCCGAGGCCACCCCCAGCACAGCCTCTGTGGGCCCA---GGTGAGTCCTGTCCTTG
gValAlaGlu{G} >>>> Target Intron 33 >>>> {ly}ThrSerPhePr
{ } 5369 bp { } ||
*AlaProGly{U}++ --{nk}UnkUnkUnkPr
AGCTCCTGGA{G}gt nn{NN}NNNNNNNNCCC
oProGlnGluProArgHisSerProGlnValLysMetAlaProThrSerSerProAla
|||| ||||||||| ||| ||||||||| |||||| |||
oProHisGluProArgArgSerGlnGlnValLysThrThrProThrGlyProProGly
CCCGCACGAGCCACGCCGCAGCCAGCAGGTGAAGACGACCCCCACAGGCCCCCCAGGA
GluProHisCysTrpProAlaGluAlaAlaLeuGlyThrGlyAlaGluProThrCysS
|||||||||||||||||||||||| ||| ||||||||||||||| |
GluProHisCysTrpProAlaGluThrAlaProArgThrGlyAlaGluProProSerS
GAGCCGCACTGCTGGCCAGCCGAGACTGCCCCGCGCACAGGTGCCGAGCCCCCCAGCA
erGlnGluGlyLysLeuArgProGluProArgArgAspGlyGluAlaGlnGluAlaAl
||||| ||||||||| |||
erGln---GlyLysLeuSerGlnGluGlnProLeuProAlaHisArgLeuProHisGl
GCCAG---GGTAAGTTGAGTCAGGAGCAGCCCCTCCCTGCCCACAGGCTGCCCCATGG
aSer{Gl} >>>> Target Intron 34 >>>> {u}ThrGlnProLeuSerSe
{ } 922 bp { }
yLeu{Gl}+- -+{n}ArgGly***AlaGlnVa
CCTG{CA}gc gg{G}CGAGGCTGAGCCCAGGT
rProProThrAlaAlaSerSerLysAlaProSerSerGlySerAlaGlnProProGlu
||||||||||||||||||||| |||||||||||| |||||| ||||||
lSerProThrAlaAlaSerSerLysValProSerSerGlyAsnAlaGlnAlaProGlu
CTCCCCCACAGCTGCCAGCTCCAAGGTCCCCAGCAGTGGGAATGCTCAGGCACCCGAG
GlyHisProGlyLysProGluProSerArgAlaLysSerArgProLeuProAsnMetP
||||||||||||||| |||||| ||| ||| ||| |||||||||||||
GlyHisProGlyLysAlaGluProGlyArgThrLysAlaArgLeuLeuProAsnMetP
GGCCACCCGGGTAAGGCAGAGCCCGGCCGCACCAAGGCACGCCTGCTGCCCAACATGC
roLysLeuValIleProSerAlaAlaThrLysPheProProGluIleThrValThrPr
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
roLysLeuValIleProSerAlaAlaThrLysPheProProGluIleThrValThrPr
CGAAGCTGGTCATCCCCTCGGCCGCCACCAAGTTCCCGCCCGAGATCACCGTCACGCC
oProThrProThrLeuLeuSerProLysGlySerIleSerGluGluThrLysGlnLys
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
oProThrProThrLeuLeuSerProLysGlySerIleSerGluGluThrLysGlnLys
GCCCACCCCGACCCTGCTGTCCCCCAAAGGCAGCATCTCCGAGGAGACCAAGCAGAAG
LeuLys >>>> Target Intron 35 >>>> SerAlaIleLeuSerAlaGlnS
|||||| 96 bp ||||||||||||||||||||||
LeuLys++ ++SerAlaIleLeuSerAlaGlnS
CTGAAGgt agTCGGCCATCCTGTCTGCCCAGT
erAlaAlaAsnValArgLysGluSerLeuCysGlnProAlaLeuGluValLeuGluTh
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
erAlaAlaAsnValArgLysGluSerLeuCysGlnProAlaLeuGluValLeuGluTh
CGGCCGCCAACGTGCGGAAGGAGAGCCTGTGCCAGCCAGCCCTGGAGGTCCTGGAGAC
rSerSerGlnGluSerSerLeuGluSerGluThrAspGluAspAspAspTyrMetAsp
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
rSerSerGlnGluSerSerLeuGluSerGluThrAspGluAspAspAspTyrMetAsp
GTCCAGCCAGGAGTCCTCGCTGGAGAGCGAGACGGACGAGGACGACGACTACATGGAC
Ile
|||
Ile
ATC
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