| Basic information |
| Official Symbol | C1RL |
| Description | complement component 1, r subcomponent-like |
| Other Aliases | C1RL1, C1RLP, C1r-LP, CLSPa |
| Other Description | C1r-like protein; C1r-like serine protease analog protein; complement C1r subcomponent-like protein; complement C1r-like proteinase |
| Mutation type | Delete and frame-shift 8:G->G |
| Location | Scaffold149011_1:182943 194770 + |
| Wiki | Wikipedia GeneCard |
| Sequence |
| C1RL |
CCAGGTCCCAGAGTCTGGGAACTATCTCTGGAAAAGCCCTCACTCCGCAAGCTGCCCAGG CATGTGGTGGCTGCTCCTCTGGGGAGCCCTCCAGGCTTGCCCCACACAAACCTCTGTCCT CTTGGCCCAGCAGCTACCTCAGCAGCTGACATCCCCCAAGTACCCAGAACCGTATCTCAA AGGCCAAGAGAGCACCACTGACATCGAGGCTCCAGAAGGCTTTGCCGTGAGGCTCATCTT CCGGGACTTCGACCTGGAGCCATCCCAGGACTGTGAACAGGACTTTGTCACAATCTCGGC CCACGGGATAGAGCCAAGCCGGTTCTGTGGCCAGCAGGAGCCCCCTCTGGGCAGCCCTCC TGGTCACAGGGAGTTCGTGTCCTCAGGGAGGACTCTGCGGCTGACCTTCCATGCACACAG CTCCTCCAAGGACAAGAGCACCCCCCTCCACAAGGGCTTCTTGGCCCTCTACCAGGCCGT GGTGAACTGTAGCCAGCCCATCGGCAAGGCCAGCGGCAGCTCGGAGGCTGTCGGCACACC TGCAGATGACCCCTCTGAGACCCAGAACCACTGCCAAGAACCCTATTACCAGACGGTACC AGCAACACTCACCTGCACAGACCGGGGAACCCGGAAGGACAGACAGGATGGGGAGCAGGC ACCTCGGTGTGAGCCTTGTGGACGGCCGGTCATCCCCATTGCCCAGAACCACAAGACCCA TGGCTCCTCCAGAGCTAAGCCAGGCAACTTCCCCTGGCAAGCCTTCACCAACATCTATGG CCGTGGAGGCGGAGCCCTGCTGGGCGACAGATGGATCCTCACCGCCGCCCATACCATCTA CCCCAAGGACAGCATCTCTGCCAGGAGGAACCTGAGCGTGGATGTCTTCCTGGGCCACAC AGACATCGAAGAGATGCTGAAACGGGGAAACCATCCCGTCCGCCGCGTTGTTGTGCATCC AGACTACCGTCAGGACGAGTCCCACAACTTTGATGGGGACATCGCACTCCTGGAGCTCCA GCACCAGGTCCCCCTGGGCCCCCATGTCCTCCCGGTCTGTCTGCCTGACAACGAGACTTT CTACCGCAGCGGCTTGTTGGGCTACGTCAGTGGGTTTGGGGTGGAGGCAGGCTGGTTAAC GACCAAGCTGAAGTACTCCAGGCTGCCCGTGGCTCCGAGAGAGGCCTGTGAGGCCTGGCT CCGACAGAGGCAGAGCACTGAGGTGTTTTCCGGCAACATGTTCTGCGTCGGAAATGAGAC GCAGATACACAGTGCCTGCCAGGGGGACAGTGGTAGTGTCTATGTGGTATGGGATGACCA TGCCCATCGCTGGGTGGCCACGGGTATCGTATCTTGGGGCATTGGGTGTGGCAAGGGGTA TGACTTCTACACCAAAGTTCTCAGCTACGTGGACTGGATCCGGAGAGTGATGGATGGCAG GGAC |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 487 | 2 | 487 | Delete and frame-shift 8:G->G |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
ProGlyProArgValTrpGlyLysTyrLeuTrpArgSerProHisSerLysGlyCysProGly
|||||||||||||||||| ||||||||| |||||||||||| |||||||||
ProGlyProArgValTrp---AsnTyrLeuTrpLysSerProHisSerAlaSerCysProGly
CCAGGTCCCAGAGTCTGGG##AACTATCTCTGGAAAAGCCCTCACTCCGCAAGCTGCCCAGGC
Ala{Me} >>>> Target Intron 1 >>>> {t}TrpTrpLeuLeuLeuTrpGlyVal
{||} 480 bp {|}|||||||||||||||||||||
Met{Me}++ ++{t}TrpTrpLeuLeuLeuTrpGlyAla
ATG{AT}gt ag{G}TGGTGGCTGCTCCTCTGGGGAGCC
LeuGlnAlaCysProThrArgGlySerValLeuLeuAlaGlnGluLeuProGlnGlnLeuThr
|||||||||||||||||| |||||||||||||||||| ||||||||||||||||||
LeuGlnAlaCysProThrGlnThrSerValLeuLeuAlaGlnGlnLeuProGlnGlnLeuThr
CTCCAGGCTTGCCCCACACAAACCTCTGTCCTCTTGGCCCAGCAGCTACCTCAGCAGCTGACA
SerProGlyTyrProGluProTyrGlyLysGlyGlnGluSerSerThrAspIleLysAlaPro
|||||| ||||||||||||||| ||||||||||||||| ||||||||| ||||||
SerProLysTyrProGluProTyrLeuLysGlyGlnGluSerThrThrAspIleGluAlaPro
TCCCCCAAGTACCCAGAACCGTATCTCAAAGGCCAAGAGAGCACCACTGACATCGAGGCTCCA
GluGlyPheAlaValArgLeuValPheGlnAspPheAspLeuGluProSerGlnAspCysAla
||||||||||||||||||||| ||| ||||||||||||||||||||||||||||||
GluGlyPheAlaValArgLeuIlePheArgAspPheAspLeuGluProSerGlnAspCysGlu
GAAGGCTTTGCCGTGAGGCTCATCTTCCGGGACTTCGACCTGGAGCCATCCCAGGACTGTGAA
GlyAspSerValThr >>>> Target Intron 2 >>>> IleSerPheValGlySerA
||| |||||| 4690 bp |||||| |||
GlnAspPheValThr++ ++IleSerAlaHisGlyIleG
CAGGACTTTGTCACAgt agATCTCGGCCCACGGGATAG
spProSerGlnPheCysGlyGlnGlnGlySerProLeuGlyArgProProGlyGlnArgG
|||||| ||||||||||||||| ||||||||| ||||||||| ||||
luProSerArgPheCysGlyGlnGlnGluProProLeuGlySerProProGlyHisArgG
AGCCAAGCCGGTTCTGTGGCCAGCAGGAGCCCCCTCTGGGCAGCCCTCCTGGTCACAGGG
luPheValSerSerGlyArgSerLeuArgLeuThrPheArgThrGlnProSerSerGluA
|||||||||||||||||||| ||||||||||||||| ||||||
luPheValSerSerGlyArgThrLeuArgLeuThrPheHisAlaHisSerSerSerLysA
AGTTCGTGTCCTCAGGGAGGACTCTGCGGCTGACCTTCCATGCACACAGCTCCTCCAAGG
snLysThrAlaHisLeuHisLysGlyPheLeuAlaLeuTyrGlnThrVal{A} >>>>
||| |||||||||||||||||||||||||||||| |||{|}
spLysSerThrProLeuHisLysGlyPheLeuAlaLeuTyrGlnAlaVal{A}++
ACAAGAGCACCCCCCTCCACAAGGGCTTCTTGGCCCTCTACCAGGCCGTG{G}gt
Target Intron 3 >>>> {la}ValAsnTyrSerGlnProIleSerGluAlaSerA
823 bp {||}|||||| |||||||||||| ||||||
++{la}ValAsnCysSerGlnProIleGlyLysAlaSerG
ag{CT}GTGAACTGTAGCCAGCCCATCGGCAAGGCCAGCG
rgGlySerGluAlaIleAsnAlaProGlyAspAsnProAlaLysValGlnAsnHisCysG
||||||||| ||| ||| ||| |||||||||||||
lySerSerGluAlaValGlyThrProAlaAspAspProSerGluThrGlnAsnHisCysG
GCAGCTCGGAGGCTGTCGGCACACCTGCAGATGACCCCTCTGAGACCCAGAACCACTGCC
lnGluProTyrTyrGlnAlaAlaAlaAla{G} >>>> Target Intron 4 >>>>
||||||||||||||||| |||{|} 138 bp
lnGluProTyrTyrGlnThrValProAla{G}++ +
AAGAACCCTATTACCAGACGGTACCAGCA{G}gt a
{ly}AlaLeuThrCysAlaThrProGlyThrTrpLysAspArgGlnAspGlyGluGluV
{||} ||||||||| |||||| |||||||||||||||||||||
+{ly}ThrLeuThrCysThrAspArgGlyThrArgLysAspArgGlnAspGlyGluGlnA
g{GG}ACACTCACCTGCACAGACCGGGGAACCCGGAAGGACAGACAGGATGGGGAGCAGG
alLeuGlnCysMetPro{V} >>>> Target Intron 5 >>>> {al}CysGlyA
||| |||{|} 4241 bp {||}|||||||
laProArgCysGluPro{V}++ ++{al}CysGlyA
CACCTCGGTGTGAGCCT{G}gt ag{TC}TGTGGAC
rgProValThrProIleAlaGlnAsnGlnThrThrLeuGlySerSerArgAlaLysLeuG
|||||||| ||||||||||||||| ||| |||||||||||||||||| |
rgProValIleProIleAlaGlnAsnHisLysThrHisGlySerSerArgAlaLysProG
GGCCGGTCATCCCCATTGCCCAGAACCACAAGACCCATGGCTCCTCCAGAGCTAAGCCAG
lyAsnPheProTrpGlnAlaPheThrSerIleHisGlyArgGlyGlyGlyAlaLeuLeuG
|||||||||||||||||||||||||| ||| |||||||||||||||||||||||||
lyAsnPheProTrpGlnAlaPheThrAsnIleTyrGlyArgGlyGlyGlyAlaLeuLeuG
GCAACTTCCCCTGGCAAGCCTTCACCAACATCTATGGCCGTGGAGGCGGAGCCCTGCTGG
lyAspArgTrpIleLeuThrAlaAlaHisThrIleTyrProLysAspSerValSerLeuA
|||||||||||||||||||||||||||||||||||||||||||||||||| ||| |
lyAspArgTrpIleLeuThrAlaAlaHisThrIleTyrProLysAspSerIleSerAlaA
GCGACAGATGGATCCTCACCGCCGCCCATACCATCTACCCCAAGGACAGCATCTCTGCCA
rgLysAsnGlnSerValAsnValPheLeuGlyHisThrAlaIleAspGluMetLeuLysL
|| ||| |||||| |||||||||||||||||| ||| ||||||||||||
rgArgAsnLeuSerValAspValPheLeuGlyHisThrAspIleGluGluMetLeuLysA
GGAGGAACCTGAGCGTGGATGTCTTCCTGGGCCACACAGACATCGAAGAGATGCTGAAAC
euGlyAsnHisProValHisArgValValValHisProAspTyrArgGlnAsnGluSerH
||||||||||||||| |||||||||||||||||||||||||||||| |||||||
rgGlyAsnHisProValArgArgValValValHisProAspTyrArgGlnAspGluSerH
GGGGAAACCATCCCGTCCGCCGCGTTGTTGTGCATCCAGACTACCGTCAGGACGAGTCCC
isAsnPheSerGlyAspIleAlaLeuLeuGluLeuGlnHisSerIleProLeuGlyProA
|||||||| |||||||||||||||||||||||||||||| ||||||||||||
isAsnPheAspGlyAspIleAlaLeuLeuGluLeuGlnHisGlnValProLeuGlyProH
ACAACTTTGATGGGGACATCGCACTCCTGGAGCTCCAGCACCAGGTCCCCCTGGGCCCCC
snValLeuProValCysLeuProAspAsnGluThrLeuTyrArgSerGlyLeuLeuGlyT
||||||||||||||||||||||||||||||||| ||||||||||||||||||||||
isValLeuProValCysLeuProAspAsnGluThrPheTyrArgSerGlyLeuLeuGlyT
ATGTCCTCCCGGTCTGTCTGCCTGACAACGAGACTTTCTACCGCAGCGGCTTGTTGGGCT
yrValSerGlyPheGlyMetGluMetGlyTrpLeuThrThrGluLeuLysTyrSerArgL
||||||||||||||||| ||| ||||||||||||||| ||||||||||||||||
yrValSerGlyPheGlyValGluAlaGlyTrpLeuThrThrLysLeuLysTyrSerArgL
ACGTCAGTGGGTTTGGGGTGGAGGCAGGCTGGTTAACGACCAAGCTGAAGTACTCCAGGC
euProValAlaProArgGluAlaCysAsnAlaTrpLeuGlnLysArgGlnArgProGluV
|||||||||||||||||||||||||| ||||||||| |||||| ||||
euProValAlaProArgGluAlaCysGluAlaTrpLeuArgGlnArgGlnSerThrGluV
TGCCCGTGGCTCCGAGAGAGGCCTGTGAGGCCTGGCTCCGACAGAGGCAGAGCACTGAGG
alPheSerAspAsnMetPheCysValGlyAspGluThrGlnArgHisSerValCysGlnG
|||||||| |||||||||||||||||| ||||||||| |||||| |||||||
alPheSerGlyAsnMetPheCysValGlyAsnGluThrGlnIleHisSerAlaCysGlnG
TGTTTTCCGGCAACATGTTCTGCGTCGGAAATGAGACGCAGATACACAGTGCCTGCCAGG
lyAspSerGlySerValTyrValValTrpAspAsnHisAlaHisHisTrpValAlaThrG
|||||||||||||||||||||||||||||||| ||||||||| |||||||||||||
lyAspSerGlySerValTyrValValTrpAspAspHisAlaHisArgTrpValAlaThrG
GGGACAGTGGTAGTGTCTATGTGGTATGGGATGACCATGCCCATCGCTGGGTGGCCACGG
lyIleValSerTrpGlyIleGlyCysGlyGluGlyTyrAspPheTyrThrLysValLeuS
||||||||||||||||||||||||||||| ||||||||||||||||||||||||||||
lyIleValSerTrpGlyIleGlyCysGlyLysGlyTyrAspPheTyrThrLysValLeuS
GTATCGTATCTTGGGGCATTGGGTGTGGCAAGGGGTATGACTTCTACACCAAAGTTCTCA
erTyrValAspTrpIleLysGlyValMetAsnGlyLysAsn
||||||||||||||||| |||||| |||
erTyrValAspTrpIleArgArgValMetAspGlyArgAsp
GCTACGTGGACTGGATCCGGAGAGTGATGGATGGCAGGGAC
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