| Basic information |
| Official Symbol | BCL2L12 |
| Description | BCL2-like 12 (proline rich) |
| Other Aliases | NA |
| Other Description | Bcl-2 related proline-rich protein; bcl-2-like protein 12; bcl-2-related proline-rich protein; bcl2-L-12 |
| Mutation type | Insert and frame-shift 45-46:R-P^C |
| Location | Scaffold000673_1:605088 596825 - |
| Wiki | Wikipedia GeneCard |
| Sequence |
| BCL2L12 |
CCCCCCTCATGCCCATTTTCGGCTTTCCGGCCACGGGCATGCTGGGAACG TCATATGCAAATTAGGATGTGGCTTAGCGCTCCGCCCCCTCCACGTTGGG GCGGTTACCAGCCTGCCTTAGTGCGCAGGCGCGGGAAAGTTGAACTAATA AAGTTGGTACAAGTTGAGTGGCGGCGGGGGCGGAGGCGGAGACGGAGGCG GAGTCGGTGGGGCCCTGGGCCAGGTGCCTCCATGGCAGGCTCTGGAGAGC TGAGAGTCCAGGAGGACACACTGCGGGTCCTAGATGCCTTCCATAGGCGC CGTGAGGCTGCCAGGACCCCTGTCCCAACCCCACCCAGGAGTCCTGCCCA AGAGGAACCAACAGACTTCCTGAGCCGCCTTCGAAGATGTCTCCCCTGCC CCCTGGGGCAGGGAGCAGCTCTCCCTGAGTCCCCGCGGCCTTGCTCTCTG CCCCTCCAGCCCTGCTATGATTCAGAGCCTGGCCCAGCTACTCCACACTT CTACGCCCTGGTCGCCCAGCGGCTGGAACAGCTAGTCCAAGAGCAACTGA GATCTCCACCCAGCCCAGAGTTACAGGGTCCCCCACCCACAGAGAAGGAA GCCCTGCTGCGAAGACTGGTGGCCTTGCTGGAGGAGGAGGCAGAAGTCAT CAACCAGAAGCTGGCCTCAGACCCTGCTCTTCGCCGGAAGCTCGTCCGTC TGTCTGCTGGTTCTTTCGCTCGCCTCTTGGAGCTGTTCTTCAGCCGGTCC GGCAGCCCTTGCTCCCGACGCTCAAGCCAAACGCTGCTGTGCCCTGGACC CCCGCCGCCATCCCCAGAGCCCCTGGCCCGCCTGGCCCTTGCCATGGAGC TGAGCCGGCGCGTGGCCCGACTGGGGGGCACCCTGGCTGGACTCAGCGTG GAGCATGTGCACAGCTTTGCTCCCTGGATCCAGGCCCAAGGGGGCTGGGA GGGTGTCCTGGCCGTTTCTCCTGTGGACTTGAACTTGCCCCTGGAC |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 334 | 9 | 334 | Insert and frame-shift 45-46:R-P^C |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
ProProLeuCysProPheLeuGlyPheArgProGluAlaCysTrpGluArgHisMetGlnIl
|||||| ||||||||| ||||||||| ||||||||||||||||||||||||||
ProProSerCysProPheSerAlaPheArgProArgAlaCysTrpGluArgHisMetGlnIl
CCCCCCTCATGCCCATTTTCGGCTTTCCGGCCACGGGCATGCTGGGAACGTCATATGCAAAT
eGluArgAlaProSerValProProPheLeuArgTrpAlaGlyTyrArg-ProGlyProVal
| ||| |||||| |||||| |||||| #||| |||
eArgMetTrpLeuSerAlaProProProProArgTrpGlyGlyTyrGln#ProAlaLeuVal
TAGGATGTGGCTTAGCGCTCCGCCCCCTCCACGTTGGGGCGGTTACCAGCCCTGCCTTAGTG
ArgArgArgGlyLysValGluLeuIleLysPheValArgValGln >>>> Target Int
|||||||||||||||||||||||||||||| ||| ||| 33 bp
ArgArgArgGlyLysValGluLeuIleLysLeuValGlnValGlu--
CGCAGGCGCGGGAAAGTTGAACTAATAAAGTTGGTACAAGTTGAGcc
ron 1 >>>> TrpArgArgProGlnValGluTrpArgArgArg<->ArgTrpGlyProGl
||||||||| ||||||||| ||||||||||||||
-+TrpArgArgGlyArgArgArgArgArgArgArgSerArgTrpGlyProGl
ggTGGCGGCGGGGGCGGAGGCGGAGACGGAGGCGGAGTCGGTGGGGCCCTGG
yPro{G} >>>> Target Intron 2 >>>> {ly}AlaSerMetAlaGlySerGluG
||||{|} 557 bp {||}|||||||||||||||||| |
yPro{G}++ ++{ly}AlaSerMetAlaGlySerGlyG
GCCA{G}gt ag{GT}GCCTCCATGGCAGGCTCTGGAG
luLeuGlyLeuArgGluAspThrLeuArgValLeuAlaAlaPheLeuArgArgGlyGluAla
||||| ||||||||||||||||||||| |||||| |||||| ||||||
luLeuArgValGlnGluAspThrLeuArgValLeuAspAlaPheHisArgArgArgGluAla
AGCTGAGAGTCCAGGAGGACACACTGCGGGTCCTAGATGCCTTCCATAGGCGCCGTGAGGCT
AlaGlySerProValProThrProPro{Ar} >>>> Target Intron 3 >>>> {g
||| ||||||||||||||||||{||} 1318 bp {|
AlaArgThrProValProThrProPro{Ar}++ ++{g
GCCAGGACCCCTGTCCCAACCCCACCC{AG}gt ag{G
}SerProAlaGlnGluGluProThrAspPheLeuSerArgLeuArgArgCysLeuProCysS
}||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
}SerProAlaGlnGluGluProThrAspPheLeuSerArgLeuArgArgCysLeuProCysP
}AGTCCTGCCCAAGAGGAACCAACAGACTTCCTGAGCCGCCTTCGAAGATGTCTCCCCTGCC
erLeuGlyArgGlyAlaAlaProSerGluSerProArgProCysSerLeuProIleArgPro
|||||| ||||||||| ||||||||||||||||||||||||||| |||
roLeuGlyGlnGlyAlaAlaLeuProGluSerProArgProCysSerLeuProLeuGlnPro
CCCTGGGGCAGGGAGCAGCTCTCCCTGAGTCCCCGCGGCCTTGCTCTCTGCCCCTCCAGCCC
CysTyrGlyLeuGluPro{G} >>>> Target Intron 4 >>>> {ly}ProAlaTh
|||||| ||||||{|} 485 bp {||}||||||||
CysTyrAspSerGluPro{G}++ ++{ly}ProAlaTh
TGCTATGATTCAGAGCCT{G}gt ag{GC}CCAGCTAC
rProAspPheTyrAlaLeuValAlaGlnArgLeuGluGlnLeuValGlnGluGlnLeuLysS
|||| ||||||||||||||||||||||||||||||||||||||||||||||||||| |
rProHisPheTyrAlaLeuValAlaGlnArgLeuGluGlnLeuValGlnGluGlnLeuArgS
TCCACACTTCTACGCCCTGGTCGCCCAGCGGCTGGAACAGCTAGTCCAAGAGCAACTGAGAT
erProProSerPro{G} >>>> Target Intron 5 >>>> {lu}LeuGlnGlyPro
||||||||||||||{|} 84 bp {||}||||||||||||
erProProSerPro{G}++ ++{lu}LeuGlnGlyPro
CTCCACCCAGCCCA{G}gt ag{AG}TTACAGGGTCCC
ProSerThrGluLysGluAlaIleLeuArgArgLeuValAlaLeuLeuGluGluGluAlaGl
||| ||||||||||||||| ||||||||||||||||||||||||||||||||||||||
ProProThrGluLysGluAlaLeuLeuArgArgLeuValAlaLeuLeuGluGluGluAlaGl
CCACCCACAGAGAAGGAAGCCCTGCTGCGAAGACTGGTGGCCTTGCTGGAGGAGGAGGCAGA
uValIleAsnGlnLys >>>> Target Intron 6 >>>> LeuAlaSerAspProAl
|||||||||||||||| 514 bp |||||||||||||||||
uValIleAsnGlnLys++ ++LeuAlaSerAspProAl
AGTCATCAACCAGAAGgt agCTGGCCTCAGACCCTGC
aLeuArgSerLysLeuValArgLeuSerSerAspSerPheAlaArgLeuValGluLeuPheC
||||||| |||||||||||||||||| ||||||||||||||| |||||||||
aLeuArgArgLysLeuValArgLeuSerAlaGlySerPheAlaArgLeuLeuGluLeuPheP
TCTTCGCCGGAAGCTCGTCCGTCTGTCTGCTGGTTCTTTCGCTCGCCTCTTGGAGCTGTTCT
ysSerArgAspAspSer<-><-><-><-><->SerArgProSerArgAlaCysProGlyPro
|||||| ||| ||| ||||||||||||
heSerArgSerGlySerProCysSerArgArgSerSerGlnThrLeuLeuCysProGlyPro
TCAGCCGGTCCGGCAGCCCTTGCTCCCGACGCTCAAGCCAAACGCTGCTGTGCCCTGGACCC
ProProProSerProGluProLeuAlaArgLeuAlaLeuAlaMetGluLeuSerArgArgVa
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ProProProSerProGluProLeuAlaArgLeuAlaLeuAlaMetGluLeuSerArgArgVa
CCGCCGCCATCCCCAGAGCCCCTGGCCCGCCTGGCCCTTGCCATGGAGCTGAGCCGGCGCGT
lAlaGlyLeuGlyGlyThrLeuAlaGlyLeuSerValGluHisValHisSerPheThrProT
|||| |||||||||||||||||||||||||||||||||||||||||||||||| ||||
lAlaArgLeuGlyGlyThrLeuAlaGlyLeuSerValGluHisValHisSerPheAlaProT
GGCCCGACTGGGGGGCACCCTGGCTGGACTCAGCGTGGAGCATGTGCACAGCTTTGCTCCCT
rpIleGlnAlaHisGlyGlyTrp >>>> Target Intron 7 >>>> GluGlyIleL
||||||||||| ||||||||| 4276 bp |||||| |
rpIleGlnAlaGlnGlyGlyTrp++ ++GluGlyValL
GGATCCAGGCCCAAGGGGGCTGGgt agGAGGGTGTCC
euAlaValSerProValAspLeuAsnLeuProLeuAsp
||||||||||||||||||||||||||||||||||||||
euAlaValSerProValAspLeuAsnLeuProLeuAsp
TGGCCGTTTCTCCTGTGGACTTGAACTTGCCCCTGGAC
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