| Basic information |
| Official Symbol | ARHGAP5 |
| Description | Rho GTPase activating protein 5 |
| Other Aliases | GFI2, RhoGAP5, p190-B, p190BRhoGAP |
| Other Description | growth factor independent 2; p100 RasGAP-associated p105 protein; p105 RhoGAP; rho GTPase-activating protein 5; rho-type GTPase-activating protein 5 |
| Mutation type | Insert and frame-shift 1162-1163: S-K^A |
| Location | Scaffold000350_1:8569586 8631209 - |
| Wiki | Wikipedia GeneCard |
| Sequence |
| ARHGAP5 |
ATGATGGCAAAAAACAAAGAGCCTCGTCCCCCATCCTATACTATCAGTGTAGTTGGACTC TCTGGGACTGAAAAAGACAAAGGTAACTGTGGAGTTGGAAAGTCTTGTTTGTGCAATAGA TTTGTACGCTCAAAAGCAGATGAATATTATCCAGAGCATACTTCTGTGCTTAGCACCATT GACTTTGGAGGACGAGTTGTAAACAATGATCACTTCTTGTACTGGGGTGACATAACACAA AATGGTGAAGATGGAGTAGAATGCAAAATACATGTTATTGAGCAAACAGAATTCATTGAT GACCAGACTTTCTTGCCTCATCGGAGTACAAATTTGCAACCATATATAAAACGTGCAGCT GCCTCTAAATTACAGTCAGCAGAAAAACTCATGTACATTTGCACTGATCAGCTAGGCTTG GAGCAAGACTTTGAACAGAAGCAAATGCCTGAAGGGAAGCTCAGTGTAGATGGATTTTTA TTGTGCATTGATGTAAGTCAGGGATGCAATAGAAAGTTTGATGATCAACTTAAATTTGTG AATAACCTTTTTGTCCAGCTATCAAAATCAAAAAAACCTGTAATAATAGCAGCAACTAAA TGTGATGAATGTGTGGATCACTATCTTAGAGAAGTTCAGGCATTTGCTTCAAACAAAAAG AACCTTCTTGTAGTAGAAACATCAGCACGATTTAATGTCAACATTGAGACATGTTTCACT GCACTGATACAAATGTTGGATAAAACTCGTGGAAAACCTAAAATTATTCCCTATCTGGAT GCTTATAAAACACAGAGACAACTTGTTGTAACAGCAACAGATAAGTTTGAAAAACTTGTG CAGACTGTGAGAGATTATCATGCAACTTGGAAAACTGTTAGTAATAAATTAAAAAATCAT CCTGATTATGAAGAATACATCAACTTAGAAGGAACAAGAAAGGCCAGAAATACATTCTCA AAACATATAGAACAACTGAAACAGGAACATATAAGAAAAAGGAGAGAAGAATATATCAAT ACTTTACCAAGAGCTTTTAATACACTTTTGCCAAATCTAGAAGAGATTGAACATTTGAAT TGGTCAGAAGCTTTGAAGTTAATGGAAAAAAGAACAGATTTCCAGTTATGTTTTGTGGTG CTAAAAAAAACACCTTGGGATAAAACTGACCATATAGACAAAATTAATGATAGACGGATC CCATTTGACCTCTTGAGCACTTTAGAAGCTGAAAAAGTCTATCAAAACCATGTACAACAT CTAATATCGGAGAAGAGGAGGGTAGAAATGAAGGAAAAATTCAAAAAGACCTTGGAAAAA ATTCAGTTTATTTCACCTGGGCAGCCATGGGAGGAAGTTATGTGCTTTGTTATGGAAGAT GAAGCTTTCAAATATATCACTGAGACAGATAGCAAAGAGGTATATGGTAGGCATCAGCGA GAAATAGTTGAAAAAGCCAAAGAAGAGTTTCAGGAAATGCTCTTTGAACATTCTGAACTT TTTTATGATTTAGATCTTAATGCAACACCAAGTTCAGATAAAATGAGTGAAATTCACACA GTTCTGAGTGAAGAACCTAGATATAAAGCTTTACAGAAACTTGCACCTGATAGGGAATCG CTTCTACTTAAGCATATAGGATTTGTTTATCATCCCACTAAAGAAACATGTCTTAGTGGC CTAAATTGTACAGATATTAAAGTGGAGCAGGTACTTGCCAGTAGAATTTTGCAGTTGGAT CATGGCCGTTCACGGTTGTATCATGACTTCTCAGATCAGAAAAGATAAATATATGGCTAA TCTTCCATTTACATTAATTCTGGCTAATCAGAGAGATTCCATCGGTAAGAATCTGCCCAT TCTTAGGCACCAAAGGCAGCATAAGTTACAGTGTCCTTTTGTAGATGTACCTGCTGGGAC ATACCCTCGTAAATTTAATGAAACCCAAATAAAGCAAGCCCTCAGAGGAGTATTAGAATC AGTTAAACACAATTTGGATGTGGTGAGCCCAGTTCCTACCAATAAGGATGTATCAGAAGC TGACTTGAGAATTGTGATGTGTGCCATGTGTGGTGATCCATTTAGTGTGGATCTTATTCT TTCACCCTTCCTTGATTCTCATTCTTGCAGTGCTGCTCAAGCTGGACAGAATAATTCCTT AATGCTTGATAAAATCATTGGTGAAAAAAGGAGGCGAATACAGATCACGATATTATCATA CCACTCCTCAATTGGAGTAAGAAAAGATGAGCTGGTTCATGGGTATATATTAGTTTACTC TGCCAAACGGAAAGCGTCAATGGGAATGCTTCGAGCATTTCTTTCAGAAGTTCAGGACAC TATTCCTGTACAACTGGTGGCAGTTACTGACAGCCAAGCAGATTTTTTTGAAAATGAGGC TATCAAAGAGTTAATGACTGAAGGAGAACACATTGCAACTGAGATCACTGCTAAATTTAC AGCATTGTATTCTTTATCTCAGTATCATCGGCAAACTGAGGTCTTTACATTGTTTTTCAG TGATGTTCTAGAGAAAAAAAATATGATAGAAAATTCCTATTTGTCTGATAGTACAAGGGA ATCAACCCATCAAAGTGAAGATGTTTTTCTACCATCTCCCAGAGACTGTTATCCCTATAA CAACTACCCTGATTCAGATGATGACACAGAAGCACCACCTCCTTACAGTCCTATTGGGGA TGATGTACAGTTGCTTCCAACACCCAGTGACCGGTCTAGATACAGGTTAGATTTGGAAGG AAATGAATACCCTGTTCATAGCACCCCAAACTGTCATGACCATGAACGCAACCATAAAGT GCCTCCACCCATTAAACCTAAACCAGTTGTACCTAAGACAAATGTGAAAAAACTGGGTCC AAACCTTTTGAAAACAATTGAAGCTGGTATTGGTAAAAATCCAAGAAAACAGACTTCCCG TGTGCCTTTGGCACATCCTGAAGATATGGATCCTACAGATAACTATGCGGAACCCGTTGA CGCAATTTTTAAACAAAAAGGCTATCCCGATGAGATTTATGTTGTCCCAGATGATAGTCA GAATCGTATTATTAAAATTAGAAATTCATTTGTAAATAACACCCAAGGAGATGAAGAAAA TGGATTTTCTGATAGAACCTCAAAAAGTCATGGGGAACGGAGACCTTCAAAATACAAATA TAAATCTAAAACCTTATTTAGTAAAAGCCAAATCATACTACAGAAGAACACATTCAGATG CAAGTGATGATGAGGCTTTCACTATTTTTTTTTTTTTGAGAGGTTTTCTCTATAGGGAGA TAGAAAGCAAAAATATCACCCCCCCCCCACGGGGGATGGCCACACTGCAATCCCTTCTCC TTTCTTCCCTTGGGATTTTGGGCACACACACACACACACACACACACACACACACACACA CACACACACCTCGCCAGAAAAAGAAAACTAAGAACTTCAATCCACCAACACGTAGAAATT GGGAAAGTAATTACTTTGGGATGCCCCTCCAGGATCTGGTTACAGCTGAGAAGCCCATAC CACTATTTGTTGAAAAGTGTGTGGCATTTATTGAAGATACATTATGTACTGAAGGACTCT ACCGTGTTAGCGGAAACAAAACTGATCAAGACAATATTCAAAAGCAGTTTGATCAACATA ATATCAATCTTGTATCAATGGAAGTAACAGTAAATGCTGTAGCTGGAGCTCTTAAAGCTT TCTTTGCAGATCTGCCAGATCCTTTAATTCCATATTCTCTTCATCCAGAACTGTTGGAAG CAGCAATCCCGGATAAGACAGAACGTCTTCATGCCTTGAAAGAAATTGTTAAAAAATTTC ATCCTGTAAACTATGATGTATTTAGATATATAATAACACATCTTAACGTGAGTCAGCAAA ATAAAATCAACCTCATGACAGCAGACAACTTGTCCATCTGCTTTTGGCCAACCTTGATGA GACCTGATTTTGAAAATCGAGAGTTTCTGTCTACCACCAAGATACATCAATCTGTTGTTG AAACATTCATTCAACAGTGTCAGTTTTTCTTTTACAATGGAGAAATTGTTGAAACTGTGA ACACTGTGGCTCCACCACCTTCAAATCCAGGACAGTTGGTGGAACCAATGGTACCACTTC AGTTACCACCACCATTGCAACCTCAGCTAATACAACCACAATTACAGACGGATCCTCTTG GAATTATA |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 1502 | 1 | 1502 | Insert and frame-shift 1162-1163: S-K^A |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
MetMetAlaLysAsnLysGluProArgProProSerTyrThrIleSerIleValGlyLeu
|||||||||||||||||||||||||||||||||||||||||||||||| |||||||||
MetMetAlaLysAsnLysGluProArgProProSerTyrThrIleSerValValGlyLeu
ATGATGGCAAAAAACAAAGAGCCTCGTCCCCCATCCTATACTATCAGTGTAGTTGGACTC
SerGlyThrGluLysAspLysGlyAsnCysGlyValGlyLysSerCysLeuCysAsnArg
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
SerGlyThrGluLysAspLysGlyAsnCysGlyValGlyLysSerCysLeuCysAsnArg
TCTGGGACTGAAAAAGACAAAGGTAACTGTGGAGTTGGAAAGTCTTGTTTGTGCAATAGA
PheValArgSerLysAlaAspGluTyrTyrProGluHisThrSerValLeuSerThrIle
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
PheValArgSerLysAlaAspGluTyrTyrProGluHisThrSerValLeuSerThrIle
TTTGTACGCTCAAAAGCAGATGAATATTATCCAGAGCATACTTCTGTGCTTAGCACCATT
AspPheGlyGlyArgValValAsnAsnAspHisPheLeuTyrTrpGlyAspIleIleGln
|||||||||||||||||||||||||||||||||||||||||||||||||||||| |||
AspPheGlyGlyArgValValAsnAsnAspHisPheLeuTyrTrpGlyAspIleThrGln
GACTTTGGAGGACGAGTTGTAAACAATGATCACTTCTTGTACTGGGGTGACATAACACAA
AsnSerGluAspGlyValGluCysLysIleHisValIleGluGlnThrGluPheIleAsp
||| ||||||||||||||||||||||||||||||||||||||||||||||||||||||
AsnGlyGluAspGlyValGluCysLysIleHisValIleGluGlnThrGluPheIleAsp
AATGGTGAAGATGGAGTAGAATGCAAAATACATGTTATTGAGCAAACAGAATTCATTGAT
AspGlnThrPheLeuProHisArgSerThrAsnLeuGlnProTyrIleLysArgAlaAla
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
AspGlnThrPheLeuProHisArgSerThrAsnLeuGlnProTyrIleLysArgAlaAla
GACCAGACTTTCTTGCCTCATCGGAGTACAAATTTGCAACCATATATAAAACGTGCAGCT
AlaSerLysLeuGlnSerAlaGluLysLeuMetTyrIleCysThrAspGlnLeuGlyLeu
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
AlaSerLysLeuGlnSerAlaGluLysLeuMetTyrIleCysThrAspGlnLeuGlyLeu
GCCTCTAAATTACAGTCAGCAGAAAAACTCATGTACATTTGCACTGATCAGCTAGGCTTG
GluGlnAspPheGluGlnLysGlnMetProGluGlyLysLeuAsnValAspGlyPheLeu
|||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
GluGlnAspPheGluGlnLysGlnMetProGluGlyLysLeuSerValAspGlyPheLeu
GAGCAAGACTTTGAACAGAAGCAAATGCCTGAAGGGAAGCTCAGTGTAGATGGATTTTTA
LeuCysIleAspValSerGlnGlyCysAsnArgLysPheAspAspGlnLeuLysPheVal
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
LeuCysIleAspValSerGlnGlyCysAsnArgLysPheAspAspGlnLeuLysPheVal
TTGTGCATTGATGTAAGTCAGGGATGCAATAGAAAGTTTGATGATCAACTTAAATTTGTG
AsnAsnLeuPheValGlnLeuSerLysSerLysLysProValIleIleAlaAlaThrLys
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
AsnAsnLeuPheValGlnLeuSerLysSerLysLysProValIleIleAlaAlaThrLys
AATAACCTTTTTGTCCAGCTATCAAAATCAAAAAAACCTGTAATAATAGCAGCAACTAAA
CysAspGluCysValAspHisTyrLeuArgGluValGlnAlaPheAlaSerAsnLysLys
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
CysAspGluCysValAspHisTyrLeuArgGluValGlnAlaPheAlaSerAsnLysLys
TGTGATGAATGTGTGGATCACTATCTTAGAGAAGTTCAGGCATTTGCTTCAAACAAAAAG
AsnLeuLeuValValGluThrSerAlaArgPheAsnValAsnIleGluThrCysPheThr
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
AsnLeuLeuValValGluThrSerAlaArgPheAsnValAsnIleGluThrCysPheThr
AACCTTCTTGTAGTAGAAACATCAGCACGATTTAATGTCAACATTGAGACATGTTTCACT
AlaLeuValGlnMetLeuAspLysThrArgSerLysProLysIleIleProTyrLeuAsp
|||||| ||||||||||||||||||||| |||||||||||||||||||||||||||
AlaLeuIleGlnMetLeuAspLysThrArgGlyLysProLysIleIleProTyrLeuAsp
GCACTGATACAAATGTTGGATAAAACTCGTGGAAAACCTAAAATTATTCCCTATCTGGAT
AlaTyrLysThrGlnArgGlnLeuValValThrAlaThrAspLysPheGluLysLeuVal
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
AlaTyrLysThrGlnArgGlnLeuValValThrAlaThrAspLysPheGluLysLeuVal
GCTTATAAAACACAGAGACAACTTGTTGTAACAGCAACAGATAAGTTTGAAAAACTTGTG
GlnThrValArgAspTyrHisAlaThrTrpLysThrValSerAsnLysLeuLysAsnHis
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GlnThrValArgAspTyrHisAlaThrTrpLysThrValSerAsnLysLeuLysAsnHis
CAGACTGTGAGAGATTATCATGCAACTTGGAAAACTGTTAGTAATAAATTAAAAAATCAT
ProAspTyrGluGluTyrIleAsnLeuGluGlyThrArgLysAlaArgAsnThrPheSer
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ProAspTyrGluGluTyrIleAsnLeuGluGlyThrArgLysAlaArgAsnThrPheSer
CCTGATTATGAAGAATACATCAACTTAGAAGGAACAAGAAAGGCCAGAAATACATTCTCA
LysHisIleGluGlnLeuLysGlnGluHisIleArgLysArgArgGluGluTyrIleAsn
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
LysHisIleGluGlnLeuLysGlnGluHisIleArgLysArgArgGluGluTyrIleAsn
AAACATATAGAACAACTGAAACAGGAACATATAAGAAAAAGGAGAGAAGAATATATCAAT
ThrLeuProArgAlaPheAsnThrLeuLeuProAsnLeuGluGluIleGluHisLeuAsn
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ThrLeuProArgAlaPheAsnThrLeuLeuProAsnLeuGluGluIleGluHisLeuAsn
ACTTTACCAAGAGCTTTTAATACACTTTTGCCAAATCTAGAAGAGATTGAACATTTGAAT
TrpSerGluAlaLeuLysLeuMetGluLysArgAlaAspPheGlnLeuCysPheValVal
||||||||||||||||||||||||||||||||| ||||||||||||||||||||||||
TrpSerGluAlaLeuLysLeuMetGluLysArgThrAspPheGlnLeuCysPheValVal
TGGTCAGAAGCTTTGAAGTTAATGGAAAAAAGAACAGATTTCCAGTTATGTTTTGTGGTG
LeuGluLysThrProTrpAspGluThrAspHisIleAspLysIleAsnAspArgArgIle
||| ||||||||||||||| ||||||||||||||||||||||||||||||||||||
LeuLysLysThrProTrpAspLysThrAspHisIleAspLysIleAsnAspArgArgIle
CTAAAAAAAACACCTTGGGATAAAACTGACCATATAGACAAAATTAATGATAGACGGATC
ProPheAspLeuLeuSerThrLeuGluAlaGluLysValTyrGlnAsnHisValGlnHis
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ProPheAspLeuLeuSerThrLeuGluAlaGluLysValTyrGlnAsnHisValGlnHis
CCATTTGACCTCTTGAGCACTTTAGAAGCTGAAAAAGTCTATCAAAACCATGTACAACAT
LeuIleSerGluLysArgArgValGluMetLysGluLysPheLysLysThrLeuGluLys
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
LeuIleSerGluLysArgArgValGluMetLysGluLysPheLysLysThrLeuGluLys
CTAATATCGGAGAAGAGGAGGGTAGAAATGAAGGAAAAATTCAAAAAGACCTTGGAAAAA
IleGlnPheIleSerProGlyGlnProTrpGluGluValMetCysPheValMetGluAsp
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
IleGlnPheIleSerProGlyGlnProTrpGluGluValMetCysPheValMetGluAsp
ATTCAGTTTATTTCACCTGGGCAGCCATGGGAGGAAGTTATGTGCTTTGTTATGGAAGAT
GluAlaTyrLysTyrIleThrGluAlaAspSerLysGluValTyrGlyArgHisGlnArg
|||||| ||||||||||||||| |||||||||||||||||||||||||||||||||
GluAlaPheLysTyrIleThrGluThrAspSerLysGluValTyrGlyArgHisGlnArg
GAAGCTTTCAAATATATCACTGAGACAGATAGCAAAGAGGTATATGGTAGGCATCAGCGA
GluIleValGluLysAlaLysGluGluPheGlnGluMetLeuPheGluHisSerGluLeu
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GluIleValGluLysAlaLysGluGluPheGlnGluMetLeuPheGluHisSerGluLeu
GAAATAGTTGAAAAAGCCAAAGAAGAGTTTCAGGAAATGCTCTTTGAACATTCTGAACTT
PheTyrAspLeuAspLeuAsnAlaThrProSerSerAspLysMetSerGluIleHisThr
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
PheTyrAspLeuAspLeuAsnAlaThrProSerSerAspLysMetSerGluIleHisThr
TTTTATGATTTAGATCTTAATGCAACACCAAGTTCAGATAAAATGAGTGAAATTCACACA
ValLeuSerGluGluProArgTyrLysAlaLeuGlnLysLeuAlaProAspArgGluSer
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ValLeuSerGluGluProArgTyrLysAlaLeuGlnLysLeuAlaProAspArgGluSer
GTTCTGAGTGAAGAACCTAGATATAAAGCTTTACAGAAACTTGCACCTGATAGGGAATCG
LeuLeuLeuLysHisIleGlyPheValTyrHisProThrLysGluThrCysLeuSerGly
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
LeuLeuLeuLysHisIleGlyPheValTyrHisProThrLysGluThrCysLeuSerGly
CTTCTACTTAAGCATATAGGATTTGTTTATCATCCCACTAAAGAAACATGTCTTAGTGGC
GlnAsnCysThrAspIleLysValGluGlnLeuLeuAlaSerSerLeuLeuGlnLeuAsp
||||||||||||||||||||||||||| ||||||||| ||||||||||||
LeuAsnCysThrAspIleLysValGluGlnValLeuAlaSerArgIleLeuGlnLeuAsp
CTAAATTGTACAGATATTAAAGTGGAGCAGGTACTTGCCAGTAGAATTTTGCAGTTGGAT
HisGlyArgLeuArgLeuTyrHisAspSerThrAsnIleAspLysValAsnLeuPheIle
||||||||| |||||||||||||||
HisGlyArgSerArgLeuTyrHisAsp---------------------------------
CATGGCCGTTCACGGTTGTATCATGACT##------------------------------
LeuGlyLysAspGlyLeuAlaGlnGluLeuAlaAsnGluIleArgThrGlnSerThrAsp
------------------------------------------------------------
------------------------------------------------------------
AspGluTyrAlaLeuAspGlyLysIleTyrGluLeuAspLeuArgProValAspAlaLys
------------------------------------------------------------
------------------------------------------------------------
SerProTyrPheLeuSerGlnLeuTrpThrAlaAlaPheLysProHisGlyCysPheCys
------------------------------------------------------------
------------------------------------------------------------
ValPheAsnSerIleGluSerLeuSerPheIleGlyGluPheIleGlyLysIleArgThrGlu
---------------------------------------------------------------
---------------------------------------------------------------
AlaSerGlnIleArgLysAspLysTyrMetAlaAsnLeuProPheThrLeuIleLeuAla
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||
---SerGlnIleArgLysAspLysTyrMetAlaAsnLeuProPheThrLeuIleLeuAla
---TCTCAGATCAGAAAAGATAAATATATGGCTAATCTTCCATTTACATTAATTCTGGCT
AsnGlnArgAspSerIleSerLysAsnLeuProIleLeuArgHisGlnGlyGlnGlnLeu
|||||||||||||||||| ||||||||||||||||||||||||||| |||
AsnGlnArgAspSerIleGlyLysAsnLeuProIleLeuArgHisGlnArgGln------
AATCAGAGAGATTCCATCGGTAAGAATCTGCCCATTCTTAGGCACCAAAGGCAG------
AlaAsnLysLeuGlnCysProPheValAspValProAlaGlyThrTyrProArgLysPhe
||||||||||||||||||||||||||||||||||||||||||||||||||||||
---HisLysLeuGlnCysProPheValAspValProAlaGlyThrTyrProArgLysPhe
---CATAAGTTACAGTGTCCTTTTGTAGATGTACCTGCTGGGACATACCCTCGTAAATTT
AsnGluThrGlnIleLysGlnAlaLeuArgGlyValLeuGluSerValLysHisAsnLeu
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
AsnGluThrGlnIleLysGlnAlaLeuArgGlyValLeuGluSerValLysHisAsnLeu
AATGAAACCCAAATAAAGCAAGCCCTCAGAGGAGTATTAGAATCAGTTAAACACAATTTG
AspValValSerProIleProAlaAsnLysAspLeuSerGluAlaAspLeuArgIleVal
||||||||||||||| ||| ||||||||| ||||||||||||||||||||||||
AspValValSerProValProThrAsnLysAspValSerGluAlaAspLeuArgIleVal
GATGTGGTGAGCCCAGTTCCTACCAATAAGGATGTATCAGAAGCTGACTTGAGAATTGTG
MetCysAlaMetCysGlyAspProPheSerValAspLeuIleLeuSerProPheLeuAsp
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
MetCysAlaMetCysGlyAspProPheSerValAspLeuIleLeuSerProPheLeuAsp
ATGTGTGCCATGTGTGGTGATCCATTTAGTGTGGATCTTATTCTTTCACCCTTCCTTGAT
SerHisSerCysSerAlaAlaGlnAlaGlyGlnAsnAsnSerLeuMetLeuAspLysIle
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
SerHisSerCysSerAlaAlaGlnAlaGlyGlnAsnAsnSerLeuMetLeuAspLysIle
TCTCATTCTTGCAGTGCTGCTCAAGCTGGACAGAATAATTCCTTAATGCTTGATAAAATC
IleGlyGluLysArgArgArgIleGlnIleThrIleLeuSerTyrHisSerSerIleGly
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
IleGlyGluLysArgArgArgIleGlnIleThrIleLeuSerTyrHisSerSerIleGly
ATTGGTGAAAAAAGGAGGCGAATACAGATCACGATATTATCATACCACTCCTCAATTGGA
ValArgLysAspGluLeuValHisGlyTyrIleLeuValTyrSerAlaLysArgLysAla
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ValArgLysAspGluLeuValHisGlyTyrIleLeuValTyrSerAlaLysArgLysAla
GTAAGAAAAGATGAGCTGGTTCATGGGTATATATTAGTTTACTCTGCCAAACGGAAAGCG
SerMetGlyMetLeuArgAlaPheLeuSerGluValGlnAspThrIleProValGlnLeu
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
SerMetGlyMetLeuArgAlaPheLeuSerGluValGlnAspThrIleProValGlnLeu
TCAATGGGAATGCTTCGAGCATTTCTTTCAGAAGTTCAGGACACTATTCCTGTACAACTG
ValAlaValThrAspSerGlnAlaAspPhePheGluAsnGluAlaIleLysGluLeuMet
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ValAlaValThrAspSerGlnAlaAspPhePheGluAsnGluAlaIleLysGluLeuMet
GTGGCAGTTACTGACAGCCAAGCAGATTTTTTTGAAAATGAGGCTATCAAAGAGTTAATG
ThrGluGlyGluHisIleAlaThrGluIleThrAlaLysPheThrAlaLeuTyrSerLeu
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ThrGluGlyGluHisIleAlaThrGluIleThrAlaLysPheThrAlaLeuTyrSerLeu
ACTGAAGGAGAACACATTGCAACTGAGATCACTGCTAAATTTACAGCATTGTATTCTTTA
SerGlnTyrHisArgGlnThrGluValPheThrLeuPhePheSerAspValLeuGluLys
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
SerGlnTyrHisArgGlnThrGluValPheThrLeuPhePheSerAspValLeuGluLys
TCTCAGTATCATCGGCAAACTGAGGTCTTTACATTGTTTTTCAGTGATGTTCTAGAGAAA
LysAsnMetIleGluAsnSerTyrLeuSerAspAsnThrArgGluSerThrHisGlnSer
||||||||||||||||||||||||||||||||| ||||||||||||||||||||||||
LysAsnMetIleGluAsnSerTyrLeuSerAspSerThrArgGluSerThrHisGlnSer
AAAAATATGATAGAAAATTCCTATTTGTCTGATAGTACAAGGGAATCAACCCATCAAAGT
GluAspValPheLeuProSerProArgAspCysPheProTyrAsnAsnTyrProAspSer
||||||||||||||||||||||||||||||||| ||||||||||||||||||||||||
GluAspValPheLeuProSerProArgAspCysTyrProTyrAsnAsnTyrProAspSer
GAAGATGTTTTTCTACCATCTCCCAGAGACTGTTATCCCTATAACAACTACCCTGATTCA
AspAspAspThrGluAlaProProProTyrSerProIleGlyAspAspValGlnLeuLeu
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
AspAspAspThrGluAlaProProProTyrSerProIleGlyAspAspValGlnLeuLeu
GATGATGACACAGAAGCACCACCTCCTTACAGTCCTATTGGGGATGATGTACAGTTGCTT
ProThrProSerAspArgSerArgTyrArgLeuAspLeuGluGlyAsnGluTyrProIle
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ProThrProSerAspArgSerArgTyrArgLeuAspLeuGluGlyAsnGluTyrProVal
CCAACACCCAGTGACCGGTCTAGATACAGGTTAGATTTGGAAGGAAATGAATACCCTGTT
HisSerThrProAsnCysHisAspHisGluArgAsnHisLysValProProProIleLys
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
HisSerThrProAsnCysHisAspHisGluArgAsnHisLysValProProProIleLys
CATAGCACCCCAAACTGTCATGACCATGAACGCAACCATAAAGTGCCTCCACCCATTAAA
ProLysProValValProLysThrAsnValLysLysLeuAspProAsnLeuLeuLysThr
||||||||||||||||||||||||||||||||||||||| ||||||||||||||||||
ProLysProValValProLysThrAsnValLysLysLeuGlyProAsnLeuLeuLysThr
CCTAAACCAGTTGTACCTAAGACAAATGTGAAAAAACTGGGTCCAAACCTTTTGAAAACA
IleGluAlaGlyIleGlyLysAsnProArgLysGlnThrSerArgValProLeuAlaHis
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
IleGluAlaGlyIleGlyLysAsnProArgLysGlnThrSerArgValProLeuAlaHis
ATTGAAGCTGGTATTGGTAAAAATCCAAGAAAACAGACTTCCCGTGTGCCTTTGGCACAT
ProGluAspMetAspProSerAspAsnTyrAlaGluProIleAspThrIlePheLysGln
|||||||||||||||||| |||||||||||||||||| ||| ||||||||||||
ProGluAspMetAspProThrAspAsnTyrAlaGluProValAspAlaIlePheLysGln
CCTGAAGATATGGATCCTACAGATAACTATGCGGAACCCGTTGACGCAATTTTTAAACAA
LysGlyTyrSerAspGluIleTyrValValProAspAspSerGlnAsnArg<->IleLys
||||||||| ||||||||||||||||||||||||||||||||||||||| ||||||
LysGlyTyrProAspGluIleTyrValValProAspAspSerGlnAsnArgIleIleLys
AAAGGCTATCCCGATGAGATTTATGTTGTCCCAGATGATAGTCAGAATCGTATTATTAAA
IleArgAsnSerPheValAsnAsnThrGlnGlyAspGluGluAsnGlyPheSerAspArg
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
IleArgAsnSerPheValAsnAsnThrGlnGlyAspGluGluAsnGlyPheSerAspArg
ATTAGAAATTCATTTGTAAATAACACCCAAGGAGATGAAGAAAATGGATTTTCTGATAGA
ThrSerLysSerHisGlyGluArgArgProSerLysTyrLysTyrLysSerLysThrLeu
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ThrSerLysSerHisGlyGluArgArgProSerLysTyrLysTyrLysSerLysThrLeu
ACCTCAAAAAGTCATGGGGAACGGAGACCTTCAAAATACAAATATAAATCTAAAACCTTA
PheSer-LysAlaLysSerTyrTyrArgArgThrHisSerAspAlaSerAspAspGluAl
||||||#|||||||||||||||||||||||||||||||||||||||||||||||||||||
PheSer#LysAlaLysSerTyrTyrArgArgThrHisSerAspAlaSerAspAspGluAl
TTTAGTAAAAGCCAAATCATACTACAGAAGAACACATTCAGATGCAAGTGATGATGAGGC
aPheThrThrSerLysThrLysArgLysGlyArgHisArg >>>> Target
||||||| ||| |||
aPheThrIlePhePhePheLeuArgGlyPheLeuTyrArg++
TTTCACTATTTTTTTTTTTTTGAGAGGTTTTCTCTATAGGgc
Intron 1 >>>> SerGluGluAspProLeuLeuSerProValGluThrTrpLysGly
||| |||
++GluIleGluSerLysAsnIleThrProProProArgGlyMetAla
gaGAGATAGAAAGCAAAAATATCACCCCCCCCCCACGGGGGATGGCC
GlyIleAspAsnProAlaIleThrSerAspGlnGluLeuAspAspLysLysMetLysLys
||| |||
ThrLeuGlnSerLeuLeuLeuSerSerLeuGlyIleLeuGlyThrHis ThrHisThr
ACACTGCAATCCCTTCTCCTTTCTTCCCTTGGGATTTTGGGCACACAC ACACACACA
LysThrHisLysValLysValLysGluAspLysLys >>>> Target Intron 1 >>>>
||||||
HisThrHisThrHisThrHisThrHisThrProArg
CACACACACACACACACACACACACACACACCTCGC
GlnLysLysLysThrLysAsnPheAsnProProThrArgArgAsnTrpGluSerAsnTyr
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GlnLysLysLysThrLysAsnPheAsnProProThrArgArgAsnTrpGluSerAsnTyr
CAGAAAAAGAAAACTAAGAACTTCAATCCACCAACACGTAGAAATTGGGAAAGTAATTAC
PheGlyMetProLeuGlnAspLeuValThrAlaGluLysProIleProLeuPheValGlu
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
PheGlyMetProLeuGlnAspLeuValThrAlaGluLysProIleProLeuPheValGlu
TTTGGGATGCCCCTCCAGGATCTGGTTACAGCTGAGAAGCCCATACCACTATTTGTTGAA
LysCysValGluPheIleGluAspThr{G} >>>> Target Intron 1 >>>> {
||||||||| |||||||||||||||{|} 14909 bp {
LysCysValAlaPheIleGluAspThr{G}++ ++{
AAGTGTGTGGCATTTATTGAAGATACA{G}gt ag{
ly}LeuCysThrGluGlyLeuTyrArgValSerGlyAsnLysThrAspGlnAspAsnIle
||}|||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ly}LeuCysThrGluGlyLeuTyrArgValSerGlyAsnLysThrAspGlnAspAsnIle
GG}TTATGTACTGAAGGACTCTACCGTGTTAGCGGAAACAAAACTGATCAAGACAATATT
GlnLysGlnPheAspGln{A} >>>> Target Intron 2 >>>> {sp}HisAsn
||||||||||||||||||{|} 3897 bp {||}||||||
GlnLysGlnPheAspGln{A}++ ++{sp}HisAsn
CAAAAGCAGTTTGATCAA{G}gt ag{AC}CATAAT
IleAsnLeuValSerMetGluValThrValAsnAlaValAlaGlyAlaLeuLysAlaPhe
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
IleAsnLeuValSerMetGluValThrValAsnAlaValAlaGlyAlaLeuLysAlaPhe
ATCAATCTTGTATCAATGGAAGTAACAGTAAATGCTGTAGCTGGAGCTCTTAAAGCTTTC
PheAlaAspLeuProAspProLeuIleProTyrSerLeuHisProGluLeuLeuGluAla
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
PheAlaAspLeuProAspProLeuIleProTyrSerLeuHisProGluLeuLeuGluAla
TTTGCAGATCTGCCAGATCCTTTAATTCCATATTCTCTTCATCCAGAACTGTTGGAAGCA
Ala{L} >>>> Target Intron 3 >>>> {ys}IleProAspLysThrGluArg
|||{|} 2992 bp {||}|||||||||||||||||||||
Ala{L}++ ++{ys}IleProAspLysThrGluArg
GCA{A}gt ag{AA}ATCCCGGATAAGACAGAACGT
LeuHisAlaLeuLysGluIleValLysLysPheHisProValAsnTyrAspValPheArg
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
LeuHisAlaLeuLysGluIleValLysLysPheHisProValAsnTyrAspValPheArg
CTTCATGCCTTGAAAGAAATTGTTAAAAAATTTCATCCTGTAAACTATGATGTATTTAGA
TyrValIleThrHisLeuAsn{Ar} >>>> Target Intron 4 >>>> {g}Val
||| |||||||||||||||{||} 4691 bp {|}|||
TyrIleIleThrHisLeuAsn{Ar}++ ++{g}Val
TATATAATAACACATCTTAAC{AG}gt ag{G}GTG
SerGlnGlnHisLysIleAsnLeuMetThrAlaAspAsnLeuSerIleCysPheTrpPro
||||||||| ||||||||||||||||||||||||||||||||||||||||||||||||
SerGlnGlnAsnLysIleAsnLeuMetThrAlaAspAsnLeuSerIleCysPheTrpPro
AGTCAGCAAAATAAAATCAACCTCATGACAGCAGACAACTTGTCCATCTGCTTTTGGCCA
ThrLeuMetArgProAspPheGluAsnArgGluPheLeuSerThrThrLysIleHisGln
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ThrLeuMetArgProAspPheGluAsnArgGluPheLeuSerThrThrLysIleHisGln
ACCTTGATGAGACCTGATTTTGAAAATCGAGAGTTTCTGTCTACCACCAAGATACATCAA
SerValValGluThrPheIleGlnGlnCysGlnPhePhePheTyrAsnGlyGluIleVal
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
SerValValGluThrPheIleGlnGlnCysGlnPhePhePheTyrAsnGlyGluIleVal
TCTGTTGTTGAAACATTCATTCAACAGTGTCAGTTTTTCTTTTACAATGGAGAAATTGTT
GluThrThrAsnIleValAlaProProProProSerAsnProGlyGlnLeuValGluPro
|||||| ||| |||||| ||||||||||||||||||||||||||||||||||||
GluThrValAsnThrValAla---ProProProSerAsnProGlyGlnLeuValGluPro
GAAACTGTGAACACTGTGGCT---CCACCACCTTCAAATCCAGGACAGTTGGTGGAACCA
MetValProLeuGlnLeuProProProLeuGlnProGlnLeuIleGlnProGlnLeuGln
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
MetValProLeuGlnLeuProProProLeuGlnProGlnLeuIleGlnProGlnLeuGln
ATGGTACCACTTCAGTTACCACCACCATTGCAACCTCAGCTAATACAACCACAATTACAG
ThrAspProLeuGlyIleIle
|||||||||||||||||||||
ThrAspProLeuGlyIleIle
ACGGATCCTCTTGGAATTATA
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